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P. Gallipoli · SciRah

Researcher profile · Semantic Scholar

P. Gallipoli

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P. Gallipoli — researcher profile on SciRah

h-index: 25
Works: 88
Citations: 2,669

Most-cited papers

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
K. Tzelepis, Hiroko Koike-Yusa, E. De Braekeleer, Yi-Long Li +23 more
2016Cell Reports630 citations Open access
Semantic Scholar
Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
D. Forte, M. García-Fernández, Abel Sánchez-Aguilera, V. Stavropoulou +20 more
2020Cell Metabolism188 citations Open access
Semantic Scholar
JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.
P. Gallipoli, Amy Cook, S. Rhodes, L. Hopcroft +5 more
2014Blood143 citations Open access
Semantic Scholar
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition
P. Gallipoli, G. Giotopoulos, K. Tzelepis, Ana S. H. Costa +12 more
2018Blood132 citations Open access
Semantic Scholar
Epigenetic reprogramming sensitizes CML stem cells to combined EZH2 and tyrosine kinase inhibition
Mary T. Scott, K. Korfi, P. Saffrey, L. Hopcroft +13 more
2016Cancer Discovery126 citations Open access
Semantic Scholar
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML
Faisal Basheer, G. Giotopoulos, Eshwar Meduri, Hai-Yang Yun +20 more
2019Journal of Experimental Medicine106 citations Open access
Semantic Scholar
Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation.
P. Gallipoli, F. Pellicanò, H. Morrison, K. Laidlaw +5 more
2013Blood99 citations Open access
Semantic Scholar
The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia
G. Giotopoulos, Wai-In Chan, SJ Horton, D. Ruau +9 more
2015Oncogene92 citations Open access
Semantic Scholar
Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex
Min Chen, P. Gallipoli, Donna DeGeer, I. Sloma +18 more
2013Journal of the National Cancer Institute88 citations Open access
Semantic Scholar
C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia.
Marie Sabatier, R. Birsen, Laura Lauture, Sarah Mouche +53 more
2023Cancer Discovery80 citations Open access
Semantic Scholar
CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.
Anuradha Tarafdar, L. Hopcroft, P. Gallipoli, F. Pellicanò +7 more
2017Blood76 citations Open access
Semantic Scholar
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4
K. Tzelepis, E. De Braekeleer, Demetrios Aspris, I. Barbieri +31 more
2018Nature Communications74 citations Open access
Semantic Scholar
Molecular MRD is strongly prognostic in patients with NPM1-mutated AML receiving venetoclax-based non-intensive therapy.
J. Othman, I. Tiong, J. O'Nions, M. Dennis +32 more
2023Blood69 citations Open access
Semantic Scholar
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors
S. Horton, G. Giotopoulos, Hai-Yang Yun, S. Vohra +27 more
2017Nature Cell Biology65 citations Open access
Semantic Scholar
Thrombosis and hemostatic abnormalities in hematological malignancies.
R. Colombo, P. Gallipoli, R. Castelli
2014Clinical Lymphoma, Myeloma & Leukemia64 citations
Semantic Scholar
Epigenetic regulators as promising therapeutic targets in acute myeloid leukemia
P. Gallipoli, G. Giotopoulos, Brian J. P. Huntly
2015Therapeutic Advances in Hematology56 citations Open access
Semantic Scholar
Cohesin-dependent regulation of gene expression during differentiation is lost in Cohesin-mutated myeloid malignancies.
D. Sasca, Hai-Yang Yun, G. Giotopoulos, Jakub Szybinski +12 more
2019Blood47 citations Open access
Semantic Scholar
A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression
G. Giotopoulos, L. van der Weyden, H. Osaki, A. Rust +12 more
2015Journal of Experimental Medicine38 citations Open access
Semantic Scholar
Biosimilar epoetin in elderly patients with low-risk myelodysplastic syndromes improves anemia, quality of life, and brain function
R. Castelli, G. L. Deliliers, R. Colombo, G. Moreo +2 more
2014Annals of Hematology38 citations
Semantic Scholar
Targeted therapy in haematological malignancies
A. Hamilton, P. Gallipoli, E. Nicholson, T. Holyoake
2010Journal of Pathology38 citations
Semantic Scholar
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia
Hannah Lawson, J. Holt-Martyn, Vilma Dembitz, Y. Kabayama +24 more
2024Nature Cancer36 citations Open access
Semantic Scholar
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death
Keith T. Woodley, Laura S Dillingh, G. Giotopoulos, Pedro Madrigal +16 more
2023Nature Communications29 citations Open access
Semantic Scholar
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 mutated myelodysplasia
S. Mian, C. Philippe, E. Maniati, P. Protopapa +19 more
2023Science Translational Medicine27 citations Open access
Semantic Scholar
Novel epigenetic therapies in hematological malignancies: Current status and beyond.
P. Gallipoli, Brian J. P. Huntly
2017Seminars in Cancer Biology26 citations Open access
Semantic Scholar
A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies
M. Dawson, G. Borthakur, Brian J. P. Huntly, A. Karadimitris +27 more
2022Clinical Cancer Research25 citations Open access
Semantic Scholar
Hurdles toward a cure for CML: the CML stem cell.
P. Gallipoli, Sheela A. Abraham, T. Holyoake
2011Hematology/Oncology Clinics of North America23 citations
Semantic Scholar
Neutrophil‐specific granule deficiency
L. McIlwaine, A. Parker, G. Sandilands, P. Gallipoli +1 more
2013British Journal of Haematology20 citations Open access
Semantic Scholar
Histone modifiers are oxygen sensors
P. Gallipoli, Brian J. P. Huntly
2019Science19 citations Open access
Semantic Scholar
High Prevalence of Heparin Induced Thrombocytopenia with Thrombosis Among Patients with Essential Thrombocytemia Carrying V617F Mutation
R. Castelli, P. Gallipoli, Riccardo Schiavon, Thomas Teatini +2 more
2018Journal of Thrombosis and Thrombolysis18 citations Open access
Semantic Scholar
Mutational synergy during leukemia induction remodels chromatin accessibility, modification and 3-Dimensional DNA topology to alter gene expression
Hai-Yang Yun, N. Narayan, S. Vohra, G. Giotopoulos +18 more
2021Nature Genetics14 citations Open access
Semantic Scholar
Assessment of physical activity in an outpatient obesity clinic in southern Italy: results from a standardized questionnaire.
C. Finelli, P. Gallipoli, E. Celentano, G. Cacace +4 more
2006NMCD. Nutrition Metabolism and Cardiovascular Diseases13 citations
Semantic Scholar
A Phase I Study of Molibresib (GSK525762), a Selective Bromodomain (BRD) and Extra Terminal Protein (BET) Inhibitor: Results from Part 1 of a Phase I/II Open Label Single Agent Study in Subjects with Non-Hodgkin's Lymphoma (NHL)
M. Dickinson, M. Kamdar, Brian J. P. Huntly, Carlos Fernández de Larrea +19 more
2018Blood12 citations
Semantic Scholar
Laboratory and clinical risk assessment to treat myelodysplatic syndromes
A. Gidaro, G. L. Deliliers, P. Gallipoli, M. Arquati +2 more
2016Clinical Chemistry and Laboratory Medicine12 citations
Semantic Scholar
Introducing a Predictive Score for Successful Treatment Free Remission in Chronic Myeloid Leukemia (CML).
S. Claudiani, S. Metelli, Rafiee Kamvar, Richard Szydlo +12 more
2019Blood11 citations Open access
Semantic Scholar
Salvage therapy with bortezomib and dexamethasone in elderly patients with relapsed/refractory multiple myeloma
R. Castelli, G. Pantaleo, P. Gallipoli, A. Gidaro +3 more
2015Anti-Cancer Drugs10 citations
Semantic Scholar
Real-World Experience of Asciminib: Factors Associated with Response
A. Innes, C. Hayden, V. Orovboni, D. Rees +26 more
2022Blood9 citations
Semantic Scholar
Pseudotumour cerebri as a manageable side effect of prolonged all‐trans retinoic acid therapy in an adult patient with acute promyelocytic leukaemia
P. Gallipoli, M. Drummond
2009European Journal of Haematology9 citations
Semantic Scholar
Multiple splenic calcifications
Andrew J. Fyfe, P. Gallipoli
2009British Journal of Haematology9 citations
Semantic Scholar
The Role of Metabolism in the Development of Personalized Therapies in Acute Myeloid Leukemia
Vilma Dembitz, P. Gallipoli
2021Frontiers in Oncology8 citations Open access
Semantic Scholar
Safety and efficacy of pulsed imatinib with or without G‐CSF versus continuous imatinib in chronic phase chronic myeloid leukaemia patients at 5 years follow‐up
P. Gallipoli, J. Stobo, N. Heaney, F. Nicolini +9 more
2013British Journal of Haematology8 citations Open access
Semantic Scholar
Restricted access to second generation tyrosine kinase inhibitors in the UK could result in suboptimal treatment for almost half of chronic myeloid leukaemia patients: results from a West of Scotland and Lothian population study
P. Gallipoli, P. Shepherd, D. Irvine, M. Drummond +1 more
2011British Journal of Haematology8 citations
Semantic Scholar
P706: ASCIMINIB USE IN CML: THE UK EXPERIENCE
A. Innes, V. Orovboni, S. Claudiani, F. Fernando +19 more
2022HemaSphere7 citations Open access
Semantic Scholar
Design, implementation and clinical utility of next generation sequencing in myeloid malignancies: acute myeloid leukaemia and myelodysplastic syndrome.
Charlotte F. M. Hughes, P. Gallipoli, Rishu Agarwal
2021Pathology (Sydney)7 citations Open access
Semantic Scholar
Increased risk of heparin induced thrombocytopenia and thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation
R. Castelli, P. Gallipoli, Riccardo Schiavon, Thomas Teatini +2 more
2018Journal of Thrombosis and Thrombolysis6 citations
Semantic Scholar
JAK 2 / STAT 5 inhibition by nilotinib with ruxolitinib contributes to the elimination of chronic phase CML CD 34 + cells in vitro and in vivo
P. Gallipoli, Amy Cook, S. Rhodes, L. Hopcroft +6 more
20146 citations
Semantic Scholar
Effects of the novel aurora kinase/JAK inhibitor, AT9283 and imatinib on Philadelphia positive cells in vitro.
Mohsin Shah, P. Gallipoli, J. Lyons, T. Holyoake +1 more
2012Blood Cells, Molecules & Diseases6 citations Open access
Semantic Scholar
Real-World Effectiveness of Asciminib in Patients with Chronic Myeloid Leukemia (CML) Harboring the T315I Mutation: A Global Chart Review Study of Patients Treated in the Asciminib Managed Access Program (MAP)
D. Milojkovic, N. Blijlevens, Yok-Lam Kwong, U. Zaidi +14 more
2023Blood5 citations Open access
Semantic Scholar
Venetoclax with Azacitidine or Low Dose Cytarabine As an Alternative to Intensive Chemotherapy in Fit Adults during the COVID19 Pandemic: Real World Data from the UK National Health Service
J. Othman, M. Amér, Ruebina Amofa, Laura Anderson +49 more
2021Blood5 citations Open access
Semantic Scholar
Does Outcome/Survival of Patients With Myelodysplastic Syndromes Should Be Predicted by Reduced Levels of ADAMTS-13? Results From a Pilot Study.
R. Castelli, L. Bergamaschini, Thomas Teatini, Luca Cilumbriello +3 more
2020Clinical Lymphoma, Myeloma & Leukemia5 citations
Semantic Scholar
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient‐derived xenografts
Vilma Dembitz, Jozef Durko, Joana Campos, Sophie C. James +3 more
2024HemaSphere4 citations Open access
Semantic Scholar

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