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R. Birsen · SciRah

Researcher profile · Semantic Scholar

R. Birsen

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R. Birsen — researcher profile on SciRah

h-index: 19
Works: 71
Citations: 1,468

Most-cited papers

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
N. Jacque, A. Ronchetti, C. Larrue, G. Meunier +19 more
2015Blood351 citations Open access
Semantic Scholar
APR-246 induces early cell death by ferroptosis in acute myeloid leukemia
R. Birsen, C. Larrue, J. Decroocq, Natacha Johnson +12 more
2021Haematologica173 citations Open access
Semantic Scholar
High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells
L. Poulain, P. Sujobert, F. Zylbersztejn, S. Barreau +22 more
2017Leukemia120 citations
Semantic Scholar
C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia.
Marie Sabatier, R. Birsen, Laura Lauture, Sarah Mouche +53 more
2023Cancer Discovery80 citations Open access
Semantic Scholar
Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein
E. Grignano, L. Cantero-Aguilar, Z. Tuerdi, T. Chabane +9 more
2023Cell Death Discovery57 citations Open access
Semantic Scholar
AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia.
Adrien Grenier, L. Poulain, J. Mondesir, A. Jacquel +18 more
2022Cell Reports51 citations Open access
Semantic Scholar
From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
E. Grignano, R. Birsen, N. Chapuis, D. Bouscary
2020Frontiers in Oncology51 citations Open access
Semantic Scholar
Management of central nervous system involvement in chronic lymphocytic leukaemia: a retrospective cohort of 30 patients
Anne Wanquet, R. Birsen, C. Bonnet, M. Boubaya +16 more
2017British Journal of Haematology47 citations Open access
Semantic Scholar
Pairing MCL‐1 inhibition with venetoclax improves therapeutic efficiency of BH3‐mimetics in AML
M. Hormi, R. Birsen, Maya Belhadj, Tony Huynh +11 more
2020European Journal of Haematology44 citations
Semantic Scholar
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia
C. Larrue, Sarah Mouche, Shan Lin, F. Simonetta +6 more
2023Leukemia43 citations Open access
Semantic Scholar
Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia
G. Meunier, R. Birsen, C. Cazelles, Maya Belhadj +8 more
2020Oncogenesis42 citations Open access
Semantic Scholar
Optical genome mapping refines cytogenetic diagnostics, prognostic stratification and provides new molecular insights in adult MDS/AML patients
Estelle Balducci, S. Kaltenbach, P. Villarese, E. Duroyon +20 more
2022Blood Cancer Journal37 citations Open access
Semantic Scholar
Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia
N. Chapuis, L. Poulain, R. Birsen, J. Tamburini +1 more
2019Frontiers in Oncology35 citations Open access
Semantic Scholar
Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models
Clément Larrue, Sarah Mouche, Paolo Angelino, Maxime Sajot +11 more
2024Science Translational Medicine30 citations Open access
Semantic Scholar
Ibrutinib responsive central nervous system involvement in chronic lymphocytic leukemia.
Anne Wanquet, R. Birsen, R. Lemal, M. Hunault +2 more
2016Blood30 citations Open access
Semantic Scholar
RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia
M. Hospital, A. Jacquel, F. Mazed, E. Saland +20 more
2018Leukemia29 citations
Semantic Scholar
RAS activation induces synthetic lethality of MEK inhibition with mitochondrial oxidative metabolism in acute myeloid leukemia
J. Decroocq, R. Birsen, C. Montersino, P. Chaskar +37 more
2022Leukemia28 citations Open access
Semantic Scholar
Efficacy and safety of high-dose etoposide cytarabine as consolidation following rituximab methotrexate temozolomide induction in newly diagnosed primary central nervous system lymphoma in immunocompetent patients
R. Birsen, L. Willems, J. Pallud, E. Blanc +16 more
2018Haematologica28 citations Open access
Semantic Scholar
Patients with Hematological Malignancies Treated with T-Cell or B-Cell Immunotherapy Remain at High Risk of Severe Forms of COVID-19 in the Omicron Era
J. Zerbit, Marion Detroit, A. Meyer, J. Decroocq +11 more
2022Viruses22 citations Open access
Semantic Scholar
Prognostic value of early 18F-FDG PET scanning evaluation in immunocompetent primary CNS lymphoma patients
R. Birsen, E. Blanc, L. Willems, B. Burroni +21 more
2018OncoTarget20 citations Open access
Semantic Scholar
Venetoclax combination therapy induces deep AML remission with eradication of leukemic stem cells and remodeling of clonal haematopoiesis
Romain Vazquez, C. Bréal, Loria Zalmai, C. Friedrich +17 more
2021Blood Cancer Journal16 citations Open access
Semantic Scholar
Severe bleeding events among critically ill patients with haematological malignancies
C. Vigneron, C. Devautour, J. Charpentier, R. Birsen +2 more
2024Annals of Intensive Care13 citations Open access
Semantic Scholar
Pharmaceutical cancer care for haematology patients on oral anticancer drugs: Findings from an economic, clinical and organisational analysis.
J. Zerbit, M. Kroemer, B. Fuchs, Marion Detroit +16 more
2022European Journal of Cancer Care13 citations
Semantic Scholar
Maternal and obstetric outcomes in women with pregnancy-associated haematological malignancies: an observational nationwide cohort study.
P. Pinson, Ismaël Boussaid, J. Decroocq, L. Chouchana +15 more
2024The Lancet Haematology12 citations Open access
Semantic Scholar
Prognostic value and oncogenic landscape of TP53 alterations in adult and pediatric T-ALL.
M. Simonin, G. Andrieu, R. Birsen, M. Balsat +17 more
2023Blood9 citations Open access
Semantic Scholar
Proton Therapy Reduces the Effective Dose to Immune Cells in Mediastinal Hodgkin Lymphoma Patients
P. Loap, L. de Marzi, J. Decroocq, R. Birsen +4 more
2024International Journal of Particle Therapy8 citations Open access
Semantic Scholar
Rare Germline Complement Factor H Variants in Patients with Paroxysmal Nocturnal Hemoglobinuria.
P. Prata, J. Galimard, F. Sicre de Fontbrune, Anna Duval +11 more
2023Blood8 citations Open access
Semantic Scholar
Multiple Myeloma in Patients over 80: A Real World Retrospective Study of First Line Conservative Approach with Bortezomib Dexamethasone Doublet Therapy and Mini-Review of Literature
Laurence Huynh, R. Birsen, L. Mora, A. Couderc +4 more
2022Cancers8 citations Open access
Semantic Scholar
A case of BK virus nephropathy without hemorrhagic cystitis after hematopoietic stem cell transplantation
M. Burbach, R. Birsen, B. Denis, A. Munier +3 more
2016Annals of Hematology7 citations
Semantic Scholar
Predictive Factors of Response to Immunotherapy in Lymphomas: A Multicentre Clinical Data Warehouse Study (PRONOSTIM)
Marion Detroit, Mathis Collier, N. Beeker, L. Willems +21 more
2023Cancers6 citations Open access
Semantic Scholar
Molecular profiling and risk stratification in solitary bone plasmacytoma
Barbara Burroni, S. Harel, R. Seror, S. Ascione +24 more
2025Leukemia5 citations
Semantic Scholar
Talc pleurodesis allows long-term remission in HIV-unrelated Human Herpesvirus 8-associated primary effusion lymphoma
R. Birsen, D. Boutboul, B. Crestani, A. Seguin-Givelet +6 more
2017Leukemia and Lymphoma5 citations
Semantic Scholar
Accuracy and safety of 101 consecutives neurosurgical procedures for newly diagnosed central nervous system lymphomas: a single-institution experience
I. Aliouat, Alessandro Moiraghi, G. Simboli, R. Birsen +13 more
2022Journal of Neuro-Oncology4 citations
Semantic Scholar
Establishing assay-specific 97.5th percentile upper reference limit for serum D-2-hydroxyglutarate for the management of patients with acute myeloid leukemia
P. Bories, S. Nakib, L. Cynober, A. Alary +6 more
2018Clinical Chemistry and Laboratory Medicine4 citations
Semantic Scholar
Tolerance of radiotherapy with concomitant glofitamab in diffuse large B cell lymphoma: a case report
P. Loap, Natacha Johnson, R. Birsen, J. Decroocq +1 more
2024Strahlentherapie und Onkologie (Print)3 citations
Semantic Scholar
Loss of hematopoietic progenitors heterogeneity is an adverse prognostic factor in lower-risk myelodysplastic neoplasms
Charles Dussiau, T. Comont, Camille Knosp, I. Vergnolle +18 more
2024Leukemia3 citations Open access
Semantic Scholar
Clinico‐biological features, treatment and prognosis of primary myeloid sarcoma: A French retrospective multi‐centric observational study
Maya Belhadj, B. Burroni, O. Kosmider, L. Willems +15 more
2023British Journal of Haematology3 citations
Semantic Scholar
AMP-Activated Protein Kinase Contributes to Apoptosis Induced by the Bcl-2 Inhibitor Venetoclax in Acute Myeloid Leukemia
Noémie Legrand, A. Pradier, L. Poulain, Sarah Mouche +4 more
2021Cancers3 citations Open access
Semantic Scholar
Exposure to the immune system during bridging radiotherapy for Car-T cells.
P. Loap, J. Decroocq, R. Birsen, Natacha Johnson +2 more
2025Cancer Radiothérapie2 citations
Semantic Scholar
Diffuse large B-cell lymphoma associated with chronic inflammation in a patient with aneurysmal thrombus of the abdominal aorta
Lucile Perrin, L. Gibault, Ismaël Boussaid, R. Birsen
2023BMJ Case Reports2 citations Open access
Semantic Scholar
[Ferroptosis, lipid metabolism, C/EBPα and therapeutic resistance in acute myeloid leukemia].
R. Birsen, Laura Lauture, J. Sarry, Jérôme Tamburini
2023Medecine sciences : M/S2 citations
Semantic Scholar
C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia
Marie Sabatier, R. Birsen, Laura Lauture, J. Dehairs +34 more
2022bioRxiv2 citations Open access
Semantic Scholar
When refeeding is not enough: severe and prolonged pancytopenia in an adolescent with anorexia nervosa
A. Loisel, A. Caunes, R. Birsen, M. Moro +2 more
2022Eating and Weight Disorders2 citations Open access
Semantic Scholar
Methaemoglobinaemia and haemolysis after rasburicase administration in a patient with G6PD deficiency
Ismaël Boussaid, J. Mondesir, N. Chapuis, R. Birsen
2022BMJ Case Reports2 citations Open access
Semantic Scholar
[Ferroptosis and cancer: Physiopathological and therapeutic implications].
R. Birsen, E. Grignano, N. Chapuis, D. Bouscary
2021Medecine sciences : M/S2 citations Open access
Semantic Scholar
Central Nervous System Involvement in Chronic Lymphocytic Leukemia: Diagnosis and Treatment in a Retrospective Cohort of Thirty Patients
Anne Wanquet, R. Birsen, S. Choquet, V. Lévy +19 more
20152 citations
Semantic Scholar
High frequency of CD95 +/CD45RA − regulatory T cells defines an immunosuppressive profile associated with MDS progression
Romain Vazquez, Nicolas Deredec, Ismael Boussaid, Pierre Boncoeur +15 more
2026British Journal of Haematology1 citations Open access
Semantic Scholar
Prevention and management of infectious diseases in pregnant women with haematological malignancies.
Sébastien Gaultier, Asmaa Tazi, Caroline Charre, André Paugam +14 more
2025The Lancet Haematology1 citations
Semantic Scholar
Persistent remission of severe rheumatoid arthritis associated with myelodysplastic syndrome upon treatment with lenalidomide.
S. Carvès, R. Birsen, J. Avouac
2024Joint Bone Spine1 citations
Semantic Scholar
Real-World Outcomes Using Front-Line Midostaurine in Combination with Intensive Chemotherapy for Patients Aged ≥ 60 Years Old with FLT3 Mutated Acute Myeloid Leukemia
Gaspar Aspas Requena, P. Dumas, Rebeca Rodriguez Veiga, S. Bertoli +27 more
2023Blood1 citations Open access
Semantic Scholar

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