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N. Chiorazzi · SciRah

Researcher profile · Semantic Scholar

N. Chiorazzi

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N. Chiorazzi — researcher profile on SciRah

h-index: 70
Works: 494
Citations: 24K

Most-cited papers

iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL.
M. Hallek, B. Cheson, D. Catovsky, F. Caligaris-cappio +14 more
2018Blood1,610 citations
Semantic Scholar
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia
G. Fabbri, A. Holmes, Mara Viganotti, C. Scuoppo +9 more
2017Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia
C. Minici, M. Gounari, Rudolf Übelhart, L. Scarfò +11 more
2017Nature Communications121 citations Open access
Semantic Scholar
Direct in vivo Evidence for Increased Proliferation of CLL Cells in Lymph Nodes Compared to Bone Marrow and Peripheral Blood
T. Herndon, Shih-Shih Chen, N. Saba, Janet Valdez +16 more
2017Leukemia117 citations Open access
Semantic Scholar
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.
A. Agathangelidis, A. Chatzidimitriou, Katerina Gemenetzi, V. Giudicelli +79 more
2020Blood116 citations Open access
Semantic Scholar
Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib.
J. Burger, Kelvin W. Li, M. Keating, M. Sivina +14 more
2017JCI Insight90 citations Open access
Semantic Scholar
IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling
P. Maity, Mayas Bilal, M. Koning, Marc Young +34 more
2020Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer
B. Yigit, Ning-Hai Wang, E. ten Hacken, Shih-Shih Chen +10 more
2019Cancer immunology research59 citations Open access
Semantic Scholar
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia
E. Young, D. Noerenberg, L. Mansouri, V. Ljungström +39 more
2016Leukemia58 citations Open access
Semantic Scholar
Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment.
Sara Serra, T. Vaisitti, V. Audrito, Cinzia Bologna +13 more
2016Blood Advances58 citations Open access
Semantic Scholar
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
Gerardo Ferrer, Byeongho Jung, P. Chiu, Rukhsana Aslam +16 more
2021Leukemia54 citations Open access
Semantic Scholar
IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia.
A. Scheffold, B. Jebaraj, E. Tausch, J. Bloehdorn +16 more
2019Blood51 citations Open access
Semantic Scholar
IL-4 rescues surface IgM expression in chronic lymphocytic leukemia.
Benchang Guo, Lu Zhang, N. Chiorazzi, T. Rothstein
2016Blood51 citations Open access
Semantic Scholar
Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution
S. Vergani, I. Korsunsky, A. Mazzarello, Gerardo Ferrer +2 more
2017Frontiers in Immunology41 citations Open access
Semantic Scholar
AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes
Catherine Tang, D. Bagnara, N. Chiorazzi, M. Scharff +1 more
2020Frontiers in Immunology30 citations Open access
Semantic Scholar
Combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 improves survival and tumor control in CLL mouse model
C. Niemann, H. Mora-Jensen, Eman L. Dadashian, Fanny Krantz +8 more
2017Clinical Cancer Research30 citations Open access
Semantic Scholar
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes
A. Xochelli, P. Baliakas, Ioannis Kavakiotis, A. Agathangelidis +58 more
2017Clinical Cancer Research30 citations Open access
Semantic Scholar
Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia
E. Murphy, D. Neuberg, L. Rassenti, G. Hayes +16 more
2017Leukemia29 citations Open access
Semantic Scholar
Musashi 2 influences chronic lymphocytic leukemia cell survival and growth making it a potential therapeutic target
F. Palacios, Xiao-Jie Yan, Gerardo Ferrer, Shih-Shih Chen +12 more
2021Leukemia28 citations Open access
Semantic Scholar
Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: documentation and cautionary note regarding cell fraction purity
Sonia Marsilio, Hossein Khiabanian, Giulia Fabbri, S. Vergani +10 more
2017Leukemia25 citations Open access
Semantic Scholar
The role of CD180 in hematological malignancies and inflammatory disorders
Kurtis Edwards, P. Lydyard, N. Kulikova, T. Tsertsvadze +3 more
2023Molecular Medicine24 citations Open access
Semantic Scholar
CXCL13 plasma levels function as a biomarker for disease activity in patients with chronic lymphocytic leukemia
M. Sivina, L. Xiao, Ekaterina Kim, A. Vaca +9 more
2020Leukemia24 citations
Semantic Scholar
AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression
P. Oppezzo, Marcelo A. Navarrete, N. Chiorazzi
2021Frontiers in Oncology23 citations Open access
Semantic Scholar
Mechanistic insights into CpG DNA and IL-15 synergy in promoting B-cell chronic lymphocytic leukemia clonal expansion
Rashmi Gupta, Xiao-Jie Yan, J. Barrientos, J. Kolitz +4 more
2018Journal of Immunology22 citations Open access
Semantic Scholar
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
P. Baliakas, M. Mattsson, A. Hadzidimitriou, E. Minga +36 more
2017Haematologica22 citations Open access
Semantic Scholar
Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation
Rosa Catera, Yun Liu, Chao Gao, Xiao-Jie Yan +8 more
2017Molecular Medicine22 citations Open access
Semantic Scholar
The involvement of microRNA in the pathogenesis of Richter syndrome
K. Van Roosbroeck, R. Bayraktar, Steliana Calin, J. Bloehdorn +15 more
2018Haematologica21 citations Open access
Semantic Scholar
Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course
D. Bagnara, Catherine Tang, Jennifer R. Brown, Siddha N. Kasar +15 more
2021Frontiers in Oncology16 citations Open access
Semantic Scholar
Celebrating 20 Years of IGHV Mutation Analysis in CLL
N. Chiorazzi, F. Stevenson
2020HemaSphere16 citations Open access
Semantic Scholar
Mechanism for IL-15-driven B-CLL cycling: Roles for AKT and STAT5 in modulating Cyclin D2 and DNA damage response proteins 1
Rashmi Gupta, Wen-Tian Li, Xiao-Jie Yan, J. Barrientos +5 more
2019Journal of Immunology15 citations Open access
Semantic Scholar
Chronic lymphocytic leukemia immunoglobulins display bacterial reactivity that converges and diverges from auto-/poly-reactivity and IGHV mutation status.
K. Hatzi, Rosa Catera, Carolina Moreno Atanasio, V. Fischetti +5 more
2016Clinical Immunology15 citations
Semantic Scholar
B cell receptor isotypes differentially associate with cell signaling, kinetics, and outcome in chronic lymphocytic leukemia
A. Mazzarello, Eva Gentner-Göbel, Marcus Dühren-von Minden, Tatyana N. Tarasenko +11 more
2021Journal of Clinical Investigation14 citations Open access
Semantic Scholar
A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice
P. Patten, Gerardo Ferrer, Shih-Shih Chen, J. Kolitz +6 more
2021Frontiers in Immunology14 citations Open access
Semantic Scholar
On statistical modeling of sequencing noise in high depth data to assess tumor evolution
R. Rabadán, G. Bhanot, Sonia Marsilio, N. Chiorazzi +2 more
2017Journal of statistical physics14 citations Open access
Semantic Scholar
CLL intraclonal fractions exhibit established and recently acquired patterns of DNA methylation.
Boris A. Bartholdy, Xiahoua Wang, Xiao-Jie Yan, M. Pascual +8 more
2020Blood Advances12 citations Open access
Semantic Scholar
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
Eleftheria Polychronidou, Ilias Kalamaras, A. Agathangelidis, L. Sutton +15 more
2018BMC Bioinformatics12 citations Open access
Semantic Scholar
Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Xenograft Model
Shih-Shih Chen, J. Barrientos, Gerardo Ferrer, Morgan King-Richards +12 more
2023Clinical Cancer Research10 citations Open access
Semantic Scholar
An IgG1-like bispecific antibody targeting CD52 and CD20 for the treatment of B-cell malignancies.
Junpeng Qi, Shih-Shih Chen, N. Chiorazzi, C. Rader
2019Methods10 citations
Semantic Scholar
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms.
P. Morande, Xiao-Jie Yan, Julieta Haydee Sepulveda-Yanez, Noé Seija +16 more
2021Blood9 citations Open access
Semantic Scholar
Potential Relevance of B-cell Maturation Pathways in Defining the Cell(s) of Origin for Chronic Lymphocytic Leukemia.
A. Ng, N. Chiorazzi
2021Hematology/Oncology Clinics of North America9 citations Open access
Semantic Scholar
Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia.
Enrique Podaza, F. Palacios, D. Croci, D. Risnik +12 more
2020Haematologica8 citations Open access
Semantic Scholar
Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status
Lauren K. Shea, K. Honjo, D. Redden, E. Tabengwa +5 more
2019Blood Cancer Journal8 citations Open access
Semantic Scholar
CLL stereotyped B-cell receptor immunoglobulin sequences are recurrent in the B-cell repertoire of healthy individuals: Apparent lack of central and early peripheral tolerance censoring
S. Vergani, D. Bagnara, A. Agathangelidis, A. Ng +9 more
2023Frontiers in Oncology7 citations Open access
Semantic Scholar
Dual Inhibition of PI3K-δ and PI3K-γ By Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Patient-Derived Xenograft Model
Shih-Shih Chen, J. Kutok, Gerardo Ferrer, Priyadarshini Ravichandran +7 more
2018Blood7 citations
Semantic Scholar
Measurement of Leukemic B-Cell Growth Kinetics in Patients with Chronic Lymphocytic Leukemia.
A. Mazzarello, M. Fitch, M. Hellerstein, N. Chiorazzi
2018Methods in molecular biology7 citations
Semantic Scholar
CLL-like monoclonal B cell lymphocytosis displays an increased inflammatory signature that is reduced in early stage chronic lymphocytic leukemia
Gonzalo Blanco, A. Puiggros, B. Sherry, L. Nonell +17 more
2021Experimental Hematology6 citations Open access
Semantic Scholar
Functional consequences of inhibition of Bruton's tyrosine kinase by ibrutinib in chronic lymphocytic leukemia
Shih-Shih Chen, N. Chiorazzi
2023Hematological Oncology5 citations Open access
Semantic Scholar
FcγRIIb expression in early stage Chronic Lymphocytic Leukemia
Rosa Bosch, Alba Mora, Eva Puy Vicente, Gerardo Ferrer +18 more
2017Leukemia and Lymphoma5 citations Open access
Semantic Scholar
Characterization of the Intraclonal Complexity of Chronic Lymphocytic Leukemia B Cells: Potential Influences of B-Cell Receptor Crosstalk with Other Stimuli
A. Mazzarello, Mark Fitch, Martina Cardillo, A. Ng +10 more
2023Cancers4 citations Open access
Semantic Scholar
Activated CLL cells regulate IL17F producing Th17 cells in miR155 dependent and outcome specific manners.
Byeongho Jung, Gerardo Ferrer, P. Chiu, Rukhsana Aslam +10 more
2022JCI Insight4 citations Open access
Semantic Scholar

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