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M. Hellerstein · SciRah

Researcher profile · Semantic Scholar

M. Hellerstein

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M. Hellerstein — researcher profile on SciRah

h-index: 75
Works: 319
Citations: 24K

Most-cited papers

Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease.
Gordon I. Smith, M. Shankaran, M. Yoshino, G. Schweitzer +10 more
2019Journal of Clinical Investigation660 citations Open access
Semantic Scholar
Origin and differentiation of human memory CD8 T cells after vaccination
Rama S. Akondy, M. Fitch, S. Edupuganti, Shu Yang +20 more
2017Nature484 citations Open access
Semantic Scholar
Strong Relation Between Muscle Mass Determined by D3-creatine Dilution, Physical Performance, and Incidence of Falls and Mobility Limitations in a Prospective Cohort of Older Men.
Peggy M. Cawthon, E. Orwoll, K. Peters, K. Ensrud +11 more
2018The journals of gerontology. Series A, Biological sciences and medical sciences188 citations Open access
Semantic Scholar
Acetyl‐CoA Carboxylase Inhibitor GS‐0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis
E. Lawitz, A. Coste, F. Poordad, N. Alkhouri +17 more
2018Clinical Gastroenterology and Hepatology187 citations
Semantic Scholar
A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism
F. Fisher, Misung Kim, L. Doridot, Jeremy C. Cunniff +6 more
2016Molecular Metabolism159 citations Open access
Semantic Scholar
Adoptive Regulatory T Cell Therapy in a Patient with Systemic Lupus Erythematosus
M. Dall'Era, Mariela L. Pauli, Kelly A. Remedios, Keyon Taravati +12 more
2019Arthritis & Rheumatology156 citations Open access
Semantic Scholar
D3‐Creatine dilution and the importance of accuracy in the assessment of skeletal muscle mass
W. Evans, M. Hellerstein, E. Orwoll, S. Cummings +1 more
2019Journal of Cachexia, Sarcopenia and Muscle146 citations Open access
Semantic Scholar
Adhesion-mediated mechanosignaling forces mitohormesis
Kevin M. Tharp, Ryo Higuchi-Sanabria, G. Timblin, Breanna Ford +23 more
2021Cell Metabolism108 citations Open access
Semantic Scholar
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood
M. Decaris, Kelvin W. Li, C. Emson, Michelle Gatmaitan +13 more
2016Hepatology97 citations Open access
Semantic Scholar
Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib.
J. Burger, Kelvin W. Li, M. Keating, M. Sivina +14 more
2017JCI Insight90 citations Open access
Semantic Scholar
Dilution of oral D3‐Creatine to measure creatine pool size and estimate skeletal muscle mass: development of a correction algorithm
M. Shankaran, G. Czerwieniec, Chancy Fessler, P. A. Wong +4 more
2018Journal of Cachexia, Sarcopenia and Muscle88 citations Open access
Semantic Scholar
What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2?
M. Hellerstein
2020Vaccine: X84 citations Open access
Semantic Scholar
Circulating protein synthesis rates reveal skeletal muscle proteome dynamics.
M. Shankaran, C. King, Thomas E. Angel, W. Holmes +8 more
2015Journal of Clinical Investigation81 citations Open access
Semantic Scholar
Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans
Q. Tang, Joey C. Leung, Yani Peng, A. Sánchez-Fueyo +18 more
2022Science Translational Medicine77 citations Open access
Semantic Scholar
Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease.
C. Cohen, Kelvin W. Li, A. Alazraki, C. Beysen +14 more
2021Journal of Clinical Investigation73 citations Open access
Semantic Scholar
Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition
W. Esler, Gregory J. Tesz, M. Hellerstein, C. Beysen +19 more
2019Science Translational Medicine63 citations
Semantic Scholar
Turnover Rates of Hepatic Collagen and Circulating Collagen-Associated Proteins in Humans with Chronic Liver Disease
M. Decaris, C. Emson, Kelvin W. Li, Michelle Gatmaitan +8 more
2015PLoS ONE59 citations Open access
Semantic Scholar
PPARα inhibition modulates multiple reprogrammed metabolic pathways in kidney cancer and attenuates tumor growth.
Omran Abu Aboud, Dallas R. Donohoe, S. Bultman, M. Fitch +3 more
2015American Journal of Physiology - Cell Physiology56 citations Open access
Semantic Scholar
Comparison of muscle/lean mass measurement methods: correlation with functional and biochemical testing
B. Buehring, E. Siglinsky, D. Krueger, W. Evans +3 more
2018Osteoporosis International52 citations
Semantic Scholar
LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity.
Diego A. Miranda, William C. Krause, A. Cazenave-Gassiot, M. Suzawa +10 more
2018JCI Insight51 citations Open access
Semantic Scholar
Increased adipose tissue fibrogenesis, not impaired expandability, is associated with nonalcoholic fatty liver disease
Joseph W. Beals, Gordon I. Smith, M. Shankaran, A. Fuchs +9 more
2021Hepatology50 citations Open access
Semantic Scholar
Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption
D. Powell, B. Zambrowicz, L. Morrow, C. Beysen +6 more
2019Journal of Clinical Endocrinology and Metabolism49 citations Open access
Semantic Scholar
Inhibition of fatty acid synthase with FT‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with non‐alcoholic fatty liver disease: Results from two early‐phase randomized trials
C. Beysen, P. Schroeder, E. Wu, J. Brevard +10 more
2020Diabetes, obesity and metabolism47 citations Open access
Semantic Scholar
Effect of resistance training and protein intake pattern on myofibrillar protein synthesis and proteome kinetics in older men in energy restriction
C. Murphy, M. Shankaran, T. Churchward-Venne, C. Mitchell +9 more
2018Journal of Physiology45 citations Open access
Semantic Scholar
Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART
C. Bacchus-Souffan, M. Fitch, J. Symons, M. Abdel-Mohsen +20 more
2021PLoS Pathogens43 citations Open access
Semantic Scholar
De novo lipogenesis is essential for platelet production in humans
K. Kelly, W. Reagan, G. Sonnenberg, Michelle F. Clasquin +19 more
2020Nature Metabolism43 citations
Semantic Scholar
CD57+ Memory T Cells Proliferate In Vivo
Raya Ahmed, K. Miners, Julio Lahoz-Beneytez, Rhiannon E. Jones +11 more
2020Cell Reports42 citations Open access
Semantic Scholar
Adhesion-mediated mechanosignaling forces mitohormesis
Kevin M. Tharp, Ryo Higuchi-Sanabria, G. Timblin, Breanna Ford +21 more
2020bioRxiv40 citations Open access
Semantic Scholar
In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans1
Candice Allister, Li-Fen Liu, C. Lamendola, Colleen M. Craig +3 more
2015Journal of Lipid Research39 citations Open access
Semantic Scholar
Differences in In Vivo Cellular Kinetics in Abdominal and Femoral Subcutaneous Adipose Tissue in Women
Ursula A. White, M. Fitch, R. Beyl, M. Hellerstein +1 more
2016Diabetes38 citations Open access
Semantic Scholar
The Importance of Muscle Versus Fat Mass in Sarcopenic Obesity: A Re-evaluation Using D3-Creatine Muscle Mass Versus DXA Lean Mass Measurements.
E. Orwoll, K. Peters, M. Hellerstein, S. Cummings +2 more
2020The journals of gerontology. Series A, Biological sciences and medical sciences36 citations Open access
Semantic Scholar
Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients
E. Lawitz, Kelvin W. Li, E. Nyangau, T. Field +9 more
2022Journal of Lipid Research34 citations Open access
Semantic Scholar
Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans.
C. Beysen, M. Ruddy, A. Stoch, L. Mixson +5 more
2018American Journal of Physiology. Endocrinology and Metabolism32 citations Open access
Semantic Scholar
Adipose depot-specific effects of 16 weeks of pioglitazone on in vivo adipogenesis in women with obesity: a randomised controlled trial
Ursula A. White, M. Fitch, R. Beyl, M. Hellerstein +1 more
2020Diabetologia31 citations Open access
Semantic Scholar
Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice
Airlia C. S. Thompson, M. Bruss, J. C. Price, Cyrus F. Khambatta +7 more
2015Aging Cell31 citations Open access
Semantic Scholar
Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats.
M. Shankaran, Todd W. Shearer, S. Stimpson, S. Turner +9 more
2016American Journal of Physiology. Endocrinology and Metabolism30 citations Open access
Semantic Scholar
An ANGPTL4–ceramide–protein kinase Cζ axis mediates chronic glucocorticoid exposure–induced hepatic steatosis and hypertriglyceridemia in mice
Tzu-Chieh Chen, Rebecca A. Lee, S. Tsai, Deepthi Kanamaluru +8 more
2019Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia
E. Murphy, D. Neuberg, L. Rassenti, G. Hayes +16 more
2017Leukemia29 citations Open access
Semantic Scholar
Association of In Vivo Adipose Tissue Cellular Kinetics With Markers of Metabolic Health in Humans
Ursula A. White, M. Fitch, R. Beyl, M. Hellerstein +1 more
2017Journal of Clinical Endocrinology and Metabolism28 citations Open access
Semantic Scholar
RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding
C. Krois, Marta G. Vučković, Priscilla Huang, Claire Zaversnik +11 more
2019Cellular and Molecular Life Sciences27 citations Open access
Semantic Scholar
Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence
D. Reeves, C. Bacchus-Souffan, Mark Fitch, M. Abdel-Mohsen +10 more
2023Nature Communications25 citations Open access
Semantic Scholar
Acetyl-CoA carboxylase (ACC) inhibitor GS-0976 leads to suppression of hepatic de novo lipogenesis and significant improvements in MRI-PDFF, MRE, and markers of fibrosis after 12 weeks of therapy in patients with NASH
E. Lawitz, F. Poordad, A. Coste, N. Loo +13 more
201725 citations
Semantic Scholar
Transcriptome and proteome dynamics of cervical remodeling in the mouse during pregnancy
S. Nallasamy, Hector H. Palacios, Rohit Setlem, M. Caraballo +5 more
2021Biology of Reproduction24 citations Open access
Semantic Scholar
Profoundly lower muscle mass and rate of contractile protein synthesis in boys with Duchenne muscular dystrophy
W. Evans, M. Shankaran, E. Smith, Carl A. Morris +5 more
2021Journal of Physiology23 citations
Semantic Scholar
HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives
Vincent Morcilla, C. Bacchus-Souffan, K. Fisher, B. Horsburgh +12 more
2021mBio22 citations Open access
Semantic Scholar
D3-creatine dilution for the noninvasive measurement of skeletal muscle mass in premature infants
W. Evans, B. Scottoline, Faryal Imam, M. Hellerstein +4 more
2020Pediatric Research21 citations
Semantic Scholar
Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls
J. Nouws, M. Fitch, Mariana Mata, N. Santoro +8 more
2019Diabetes21 citations Open access
Semantic Scholar
Recent advances for measurement of protein synthesis rates, use of the ‘Virtual Biopsy’ approach, and measurement of muscle mass
M. Hellerstein, W. Evans
2017Current opinion in clinical nutrition and metabolic care21 citations
Semantic Scholar
Effects of testosterone on mixed-muscle protein synthesis and proteome dynamics during energy deficit.
Emily E. Howard, M. Shankaran, Willian J Evans, C. Berryman +13 more
2022Journal of Clinical Endocrinology and Metabolism19 citations Open access
Semantic Scholar
Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination
V. Zarnitsyna, Rama S. Akondy, H. Ahmed, Donald J. McGuire +7 more
2021bioRxiv17 citations Open access
Semantic Scholar

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