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P. Oppezzo · SciRah

Researcher profile · Semantic Scholar

P. Oppezzo

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P. Oppezzo — researcher profile on SciRah

h-index: 23
Works: 89
Citations: 2,009

Most-cited papers

The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia.
P. Oppezzo, Y. Vasconcelos, C. Settegrana, D. Jeannel +10 more
2005Blood148 citations Open access
Semantic Scholar
Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation.
P. Oppezzo, F. Vuillier, Y. Vasconcelos, G. Dumas +4 more
2003Blood136 citations Open access
Semantic Scholar
Antibody-dependent cell cytotoxicity synapses form in mice during tumor-specific antibody immunotherapy.
P. Hubert, A. Heitzmann, S. Viel, André Nicolas +5 more
2011Cancer Research115 citations Open access
Semantic Scholar
Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia.
Y. Vasconcelos, F. Davi, V. Lévy, P. Oppezzo +8 more
2003Journal of Clinical Oncology96 citations
Semantic Scholar
High expression of AID and active class switch recombination might account for a more aggressive disease in unmutated CLL patients: link with an activated microenvironment in CLL disease.
F. Palacios, Pilar Moreno, P. Morande, C. Abreu +8 more
2010Blood93 citations Open access
Semantic Scholar
Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation and folding defects of the mu and CD79a chains.
F. Vuillier, G. Dumas, C. Magnac, M. Prevost +5 more
2005Blood88 citations
Semantic Scholar
S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression.
Daniel Prieto, Natalia Sotelo, Noé Seija, Sandra Sernbo +10 more
2017Blood84 citations Open access
Semantic Scholar
Predictive value of serum thymidine kinase level for Ig-V mutational status in B-CLL
C. Magnac, Raphaël Porcher, F. Davi, J. Nataf +6 more
2003Leukemia75 citations Open access
Semantic Scholar
Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase*
A. G. Watts, P. Oppezzo, S. Withers, P. Alzari +1 more
2006Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Activation of the PI3K/AKT pathway by microRNA-22 results in CLL B-cell proliferation
F. Palacios, C. Abreu, Daniel Prieto, P. Morande +9 more
2014Leukemia72 citations Open access
Semantic Scholar
Tuning different expression parameters to achieve soluble recombinant proteins in E. coli: Advantages of high‐throughput screening
A. Correa, P. Oppezzo
2011Biotechnology Journal65 citations
Semantic Scholar
Potent and Specific Inhibition of Glycosidases by Small Artificial Binding Proteins (Affitins)
A. Correa, S. Pacheco, A. Mechaly, G. Obal +5 more
2014PLoS ONE47 citations Open access
Semantic Scholar
“Role of the B-cell receptor and the microenvironment in chronic lymphocytic leukemia''
P. Oppezzo, G. Dighiero
2013Blood Cancer Journal47 citations Open access
Semantic Scholar
Gene expression profiling of chronic lymphocytic leukemia can discriminate cases with stable disease and mutated Ig genes from those with progressive disease and unmutated Ig genes
Y. Vasconcelos, J. de Vos, L. Vallat, T. Rème +13 more
2005Leukemia45 citations
Semantic Scholar
Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cells.
P. Oppezzo, G. Dumas, A. Lalanne, B. Payelle‐Brogard +4 more
2005Blood41 citations
Semantic Scholar
Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells
P. Oppezzo, C. Magnac, Sergio Bianchi, F. Vuillier +6 more
2002Leukemia40 citations Open access
Semantic Scholar
Overcoming the solubility problem in E. coli: available approaches for recombinant protein production.
A. Correa, P. Oppezzo
2015Methods in molecular biology37 citations
Semantic Scholar
Human endogenous retrovirus np9 gene is over expressed in chronic lymphocytic leukemia patients
Sabrina Fischer, N. Echeverría, G. Moratorio, A. I. Landoni +4 more
2014Leukemia Research Reports35 citations Open access
Semantic Scholar
Structure of a human IgA1 Fab fragment at 1.55 Å resolution: potential effect of the constant domains on antigen-affinity modulation.
A. Correa, F. Trajtenberg, G. Obal, O. Pritsch +3 more
2013Acta Crystallographica Section D: Biological Crystallography35 citations Open access
Semantic Scholar
Generation of a vector suite for protein solubility screening
A. Correa, Claudia K. Ortega, G. Obal, P. Alzari +2 more
2014Frontiers in Microbiology29 citations Open access
Semantic Scholar
GALNT11 as a new molecular marker in chronic lymphocytic leukemia.
M. Libisch, M. Casas, Ml Chiribao, Pilar Moreno +4 more
2014Gene28 citations
Semantic Scholar
Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen
C. Sedlik, A. Heitzmann, S. Viel, Rafik Ait Sarkouh +11 more
2016Oncoimmunology25 citations Open access
Semantic Scholar
Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity.
P. Oppezzo, G. Obal, M. Baraibar, O. Pritsch +2 more
2011Biochimica et Biophysica Acta25 citations
Semantic Scholar
AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression
P. Oppezzo, Marcelo A. Navarrete, N. Chiorazzi
2021Frontiers in Oncology23 citations Open access
Semantic Scholar
Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia: New Insights into Leukemic Progression
Daniel Prieto, P. Oppezzo
2017Molecules23 citations Open access
Semantic Scholar
Chronic Lymphocytic Leukemia Cells Bind and Present the Erythrocyte Protein Band 3: Possible Role as Initiators of Autoimmune Hemolytic Anemia1
J. Galletti, Cristian Cañones, P. Morande, Mercedes Borge +5 more
2008Journal of Immunology23 citations Open access
Semantic Scholar
Post-transcriptional regulation of inducible nitric oxide synthase in chronic lymphocytic leukemia B cells in pro- and antiapoptotic culture conditions
A. Tiscornia, Alfonso Cayota, A. I. Landoni, C. Brito +6 more
2004Leukemia23 citations Open access
Semantic Scholar
Docetaxel in chitosan-based nanocapsules conjugated with an anti-Tn antigen mouse/human chimeric antibody as a promising targeting strategy of lung tumors.
Analía Castro, N. Berois, A. Malanga, Claudia K. Ortega +5 more
2021International Journal of Biological Macromolecules22 citations
Semantic Scholar
Idiotype‐pulsed dendritic cells are able to induce antitumoral cytotoxic CD8 cells in chronic lymphocytic leukaemia
F. Vuillier, K. Maloum, E. Thomas, C. Magnac +5 more
2003British Journal of Haematology22 citations Open access
Semantic Scholar
The LPL / ADAM 29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia
P. Oppezzo, Y. Vasconcelos, C. Settegrana, D. Jeannel +10 more
200521 citations
Semantic Scholar
The Expression of Sphingosine-1 Phosphate Receptor-1 in Chronic Lymphocytic Leukemia Cells Is Impaired by Tumor Microenvironmental Signals and Enhanced by Piceatannol and R406
Mercedes Borge, Federico Remes Lenicov, P. Nannini, María M. de los Ríos Alicandú +9 more
2014Journal of Immunology20 citations Open access
Semantic Scholar
Methylation status regulates lipoprotein lipase expression in chronic lymphocytic leukemia
C. Abreu, Pilar Moreno, F. Palacios, Mercedes Borge +7 more
2013Leukemia and Lymphoma20 citations Open access
Semantic Scholar
What do somatic hypermutation and class switch recombination teach us about chronic lymphocytic leukaemia pathogenesis?
P. Oppezzo, G. Dighiero
2005Current Topics in Microbiology and Immunology20 citations
Semantic Scholar
Tn antigen is a pre‐cancerous biomarker in breast tissue and serum in n‐nitrosomethylurea‐induced rat mammary carcinogenesis
A. Babino, P. Oppezzo, S. Bianco, E. Barrios +3 more
200019 citations
Semantic Scholar
PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease
Maite Duhalde Vega, D. Olivera, Gustavo Gastão Davanzo, M. Bertullo +26 more
2022Science Advances18 citations Open access
Semantic Scholar
Lipoprotein lipase expression in unmutated CLL patients is the consequence of a demethylation process induced by the microenvironment
Pilar Moreno, C. Abreu, Mercedes Borge, F. Palacios +9 more
2013Leukemia18 citations Open access
Semantic Scholar
Somatic mutations can lead to a loss of superantigenic and polyreactive binding
P. Oppezzo, G. Dumas, J. Bouvet, C. Robello +4 more
2004European Journal of Immunology18 citations Open access
Semantic Scholar
Dissecting chronic lymphocytic leukemia microenvironment signals in patients with unmutated disease: microRNA-22 regulates phosphatase and tensin homolog/AKT/FOXO1 pathway in proliferative leukemic cells
F. Palacios, Daniel Prieto, C. Abreu, S. Ruiz +5 more
2015Leukemia and Lymphoma17 citations
Semantic Scholar
HSP90 inhibitors decrease AID levels and activity in mice and in human cells
D. Montamat-Sicotte, Ludivine C. Litzler, C. Abreu, Shiva Safavi +6 more
2015European Journal of Immunology16 citations Open access
Semantic Scholar
Naturally occurring mutation affecting the MyD88-binding site of TNFRSF13B impairs triggering of class switch recombination
M. B. Almejun, M. Cols, M. Zelazko, M. Oleastro +4 more
2013European Journal of Immunology16 citations Open access
Semantic Scholar
Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia.
P. Morande, M. Sivina, Angimar Uriepero, Noé Seija +6 more
2019Blood15 citations Open access
Semantic Scholar
Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells
M. B. Almejun, Mercedes Borge, Ana Colado, E. Elías +14 more
2017Haematologica13 citations Open access
Semantic Scholar
Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification
Claudia K. Ortega, Daniel Prieto, C. Abreu, P. Oppezzo +1 more
2018Frontiers in Microbiology12 citations Open access
Semantic Scholar
TGF-β/SMAD Pathway Is Modulated by miR-26b-5p: Another Piece in the Puzzle of Chronic Lymphocytic Leukemia Progression
M. Márquez, Sandra Sernbo, Eugenia Payque, Rita Uria +14 more
2022Cancers11 citations Open access
Semantic Scholar
Tn antigen is a pre-cancerous biomarker in breast tissue and serum in n-nitrosomethylurea-induced rat mammary carcinogenesis.
A. Babino, P. Oppezzo, S. Bianco, E. Barrios +3 more
2000International Journal of Cancer11 citations
Semantic Scholar
LPL protein in Chronic Lymphocytic Leukaemia have different origins in Mutated and Unmutated patients. Advances for a new prognostic marker in CLL
Daniel Prieto, Noé Seija, Angimar Uriepero, T. Souto-Padrón +9 more
2018British Journal of Haematology10 citations Open access
Semantic Scholar
Noninfectious complications in patients with pediatric‐onset common variable immunodeficiency correlated with defects in somatic hypermutation but not in class‐switch recombination
M. B. Almejun, B. Campos, V. Patiño, M. Galicchio +4 more
2017Journal of Allergy and Clinical Immunology10 citations Open access
Semantic Scholar
AID overexpression leads to aggressive murine CLL and non-Ig mutations that mirror human neoplasms.
P. Morande, Xiao-Jie Yan, Julieta Haydee Sepulveda-Yanez, Noé Seija +16 more
2021Blood9 citations Open access
Semantic Scholar
Overview of High-Throughput Cloning Methods for the Post-genomic Era.
Claudia K. Ortega, C. Abreu, P. Oppezzo, A. Correa
2019Methods in molecular biology9 citations
Semantic Scholar
Distinctive IGHV gene usage and stereotyped receptors in South American patients with chronic lymphocytic leukemia
Carmen Stanganelli, D. Torres, Claudia K. Ortega, Natalia Sotelo +26 more
2019Hematological Oncology9 citations
Semantic Scholar

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