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A. Holmes · SciRah

Researcher profile · Semantic Scholar

A. Holmes

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A. Holmes — researcher profile on SciRah

h-index: 25
Works: 59
Citations: 6,333

Most-cited papers

BRAF MUTATIONS IN HAIRY CELL LEUKEMIA
E. Tiacci, V. Trifonov, G. Schiavoni, A. Holmes +32 more
2011New England Journal of Medicine1,067 citations Open access
Semantic Scholar
tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma
R. Maute, C. Schneider, P. Sumazin, A. Holmes +3 more
2013Proceedings of the National Academy of Sciences of the United States of America562 citations Open access
Semantic Scholar
Genetics of follicular lymphoma transformation
L. Pasqualucci, Hossein Khiabanian, Marco Fangazio, Mansi Vasishtha +15 more
2014Cell Reports553 citations Open access
Semantic Scholar
Combined Genetic Inactivation of Beta2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B-cell Lymphoma
Madhavi Challa-Malladi, Y. Lieu, Olivia Califano, A. Holmes +5 more
2011Cancer Cell436 citations Open access
Semantic Scholar
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
Jiyuan Zhang, D. Dominguez-Sola, Shafinaz Hussein, Ji-Eun Lee +9 more
2015Nature Medicine431 citations Open access
Semantic Scholar
Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas.
G. Victora, D. Dominguez-Sola, A. Holmes, S. Deroubaix +2 more
2012Blood392 citations Open access
Semantic Scholar
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development
D. Rossi, V. Trifonov, Marco Fangazio, A. Bruscaggin +36 more
2012Journal of Experimental Medicine386 citations Open access
Semantic Scholar
Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome
G. Fabbri, Hossein Khiabanian, A. Holmes, Ji-Guang Wang +5 more
2013Journal of Experimental Medicine296 citations Open access
Semantic Scholar
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype.
V. Grossmann, E. Tiacci, A. Holmes, A. Kohlmann +32 more
2011Blood252 citations Open access
Semantic Scholar
The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program.
D. Dominguez-Sola, Jennifer E. Kung, A. Holmes, Victoria A. Wells +3 more
2015Immunity232 citations Open access
Semantic Scholar
The Crebbp acetyltransferase is a haploinsufficient tumor suppressor in B cell lymphoma
Jiyuan Zhang, Sofija Vlasevska, Victoria A. Wells, Sarah Nataraj +9 more
2017Cancer Discovery196 citations Open access
Semantic Scholar
Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome
A. Holmes, C. Corinaldesi, Qiong Shen, Rahul Kumar +7 more
2020Journal of Experimental Medicine174 citations Open access
Semantic Scholar
The genetics of nodal marginal zone lymphoma.
V. Spina, Hossein Khiabanian, M. Messina, S. Monti +25 more
2016Blood162 citations Open access
Semantic Scholar
BCL6 positively regulates AID and germinal center gene expression via repression of miR-155
K. Basso, C. Schneider, Qiong Shen, A. Holmes +3 more
2012Journal of Experimental Medicine142 citations Open access
Semantic Scholar
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
Stefanie N. Meyer, C. Scuoppo, Sofija Vlasevska, E. Bal +10 more
2019Immunity135 citations Open access
Semantic Scholar
Common nonmutational NOTCH1 activation in chronic lymphocytic leukemia
G. Fabbri, A. Holmes, Mara Viganotti, C. Scuoppo +9 more
2017Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Super-Enhancer Hypermutation Alters Oncogene Expression in B-cell Lymphoma
E. Bal, Rahul Kumar, Mohammad Hadigol, A. Holmes +12 more
2022Nature111 citations Open access
Semantic Scholar
Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness.
M. Messina, I. Del Giudice, Hossein Khiabanian, D. Rossi +14 more
2014Blood96 citations Open access
Semantic Scholar
microRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas
C. Schneider, Manu Setty, A. Holmes, R. Maute +5 more
2014Proceedings of the National Academy of Sciences of the United States of America95 citations Open access
Semantic Scholar
MEF2B instructs germinal center development and acts as an oncogene in B cell lymphomagenesis
P. Brescia, C. Schneider, A. Holmes, Qiong Shen +4 more
2018Cancer Cell93 citations Open access
Semantic Scholar
Network Analysis of Global Influenza Spread
J. Chan, A. Holmes, R. Rabadán
2010PLoS Comput. Biol.53 citations Open access
Semantic Scholar
Discovering Disease Associations by Integrating Electronic Clinical Data and Medical Literature
A. Holmes, Alexander Hawson, Feng Liu, Carol Friedman +2 more
2011PLoS ONE51 citations Open access
Semantic Scholar
Spatial Simulations of Myxobacterial Development
A. Holmes, Sara Kalvala, D. Whitworth
2010PLoS Comput. Biol.33 citations Open access
Semantic Scholar
Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes
M. Messina, S. Chiaretti, Ji-Guang Wang, A. L. Fedullo +18 more
2016OncoTarget29 citations Open access
Semantic Scholar
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion
Demis Menolfi, Brian J. Lee, Hanwen Zhang, Wen-Xia Jiang +8 more
2023bioRxiv26 citations Open access
Semantic Scholar
Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
Mark P. Roberto, G. Varano, Rosa Viñas-Castells, A. Holmes +5 more
2021Immunity25 citations Open access
Semantic Scholar
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion
Demis Menolfi, Brian J. Lee, Hanwen Zhang, Wen-Xia Jiang +8 more
2023Nature Communications23 citations Open access
Semantic Scholar
Genomic and proteomic characterization of two novel siphovirus infecting the sedentary facultative epibiont cyanobacterium Acaryochloris marina.
Yi‐Wah Chan, A. Millard, P. Wheatley, A. Holmes +7 more
2015Environmental Microbiology19 citations Open access
Semantic Scholar
Discovery of cyanophage genomes which contain mitochondrial DNA polymerase.
Yi‐Wah Chan, Remus Mohr, A. Millard, A. Holmes +6 more
2011Molecular biology and evolution19 citations Open access
Semantic Scholar
Signs of the 2009 Influenza Pandemic in the New York-Presbyterian Hospital Electronic Health Records
Hossein Khiabanian, A. Holmes, Brendan J. Kelly, M. Gururaj +2 more
2010PLoS ONE18 citations Open access
Semantic Scholar
KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells
Sofija Vlasevska, L. Garcia-Ibanez, R. Duval, A. Holmes +9 more
2023Proceedings of the National Academy of Sciences of the United States of America14 citations Open access
Semantic Scholar
Tracking Immunoglobulin Repertoire and Transcriptomic Changes in Germinal Center B Cells by Single-Cell Analysis
C. Corinaldesi, A. Holmes, Qiong Shen, E. Grunstein +3 more
2022Frontiers in Immunology14 citations Open access
Semantic Scholar
The Coding Genome of Nodal Marginal Zone Lymphoma Reveals Recurrent Molecular Alterations of PTPRD and Other Jak/Stat Signaling Genes
V. Spina, Hossein Khiabanian, A. Bruscaggin, M. Messina +22 more
201413 citations Open access
Semantic Scholar
An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways
L. Mussolin, A. Holmes, C. Romualdi, G. Sales +5 more
2014Leukemia13 citations
Semantic Scholar
Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance
Clarissa Corinaldesi, A. Holmes, G. Martire, A. Tosato +21 more
2024Leukemia11 citations Open access
Semantic Scholar
miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma
A. Garbin, F. Lovisa, A. Holmes, C. C. Damanti +10 more
2020Haematologica11 citations Open access
Semantic Scholar
Deep learning-based classifier of diffuse large B-cell lymphoma cell-of-origin with clinical outcome.
A. Viswanathan, Kavita Kundal, A. Sengupta, Ambuj Kumar +3 more
2022Briefings in Functional Genomics9 citations Open access
Semantic Scholar
Phosphate Acquisition Components of the Myxococcus xanthus Pho Regulon Are Regulated by both Phosphate Availability and Development
D. Whitworth, A. Holmes, Alistair G. Irvine, D. Hodgson +1 more
2008Journal of Bacteriology9 citations Open access
Semantic Scholar
MEF2B C-terminal mutations enhance transcriptional activity and stability to drive B cell lymphomagenesis
Chuan-Jiang Yu, Qiong Shen, A. Holmes, Tongwei Mo +9 more
2024Nature Communications8 citations Open access
Semantic Scholar
Author Correction: Super-enhancer hypermutation alters oncogene expression in B cell lymphoma
E. Bal, Rahul Kumar, Mohammad Hadigol, A. Holmes +12 more
2022Nature2 citations Open access
Semantic Scholar
Role of FOXO1 in Germinal Center Development and Lymphomagenesis
D. Dominguez-Sola, Jennifer E. Kung, Victoria A. Wells, A. Holmes +3 more
20142 citations
Semantic Scholar
Differential Role of Crebbp Missense and Truncating Mutations in the Malignant Transformation of Germinal Center B Cells
Chuan-Jiang Yu, Mara Holloman, A. Kim, Yunchao Chang +8 more
2024Blood1 citations Open access
Semantic Scholar
17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023.
E. Bal, C. Corinaldesi, A. Holmes, L. Pasqualucci +2 more
2023Hematological Oncology1 citations Open access
Semantic Scholar
BTG2 Super-Enhancer Mutations Disrupt TFAP4 Binding and Deregulate BTG2 Expression in Diffuse Large B-Cell Lymphoma
Pantaleo De Simone, Elodie Bal, A. Holmes, L. Hilton +5 more
2023Blood1 citations
Semantic Scholar
PERVASIVE HYPERMUTATION OF SUPER‐ENHANCER REGIONS DYSREGULATES ONCOGENE EXPRESSION IN DIFFUSE LARGE B‐CELL LYMPHOMA
E. Bal, Rahul Kumar, M. Hadigo, A. Holmes +4 more
2021Hematological Oncology1 citations Open access
Semantic Scholar
Abstract PO-40: FOXO1 mutations mimic positive selection signals to promote germinal center B-cell expansion and lymphomagenesis
Mark P. Roberto, G. Varano, Rosa Viñas-Castells, A. Holmes +4 more
20201 citations
Semantic Scholar
Myxobacteria Motility: a novel 3D model of rippling behaviour in Myxococcus xanthus
A. Holmes, Sara Kalvala, D. Whitworth
20091 citations
Semantic Scholar
Single-Cell Transcriptomic Analysis of Normal and Malignant B Cells.
A. Holmes, Clarissa Corinaldesi, Katia Basso
2025Methods in molecular biology0 citations
Semantic Scholar
Role of Glucocorticoid Receptor in Normal and Malignant Germinal Center B Cells
Clarissa Corinaldesi, A. Holmes, Elodie Bal, Zeinab Amini-Farsani +4 more
2024Blood0 citations
Semantic Scholar
Abstract P04: Role of glucocorticoid receptor in normal and malignant germinal center B cells
Clarissa Corinaldesi, A. Holmes, Elodie Bal, L. Pasqualucci +2 more
2024Blood Cancer Discovery0 citations
Semantic Scholar

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L. Pasqualucci×27
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D. Dominguez-Sola×7

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Rahul Kumar — researcher profile on SciRah