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X. Declèves · SciRah

Researcher profile · Semantic Scholar

X. Declèves

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X. Declèves — researcher profile on SciRah

h-index: 41
Works: 166
Citations: 5,567

Most-cited papers

Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface
A. Boulay, B. Saubaméa, Nico Adam, Stéphanie Chasseigneaux +14 more
2017Cell Discovery169 citations Open access
Semantic Scholar
ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas
David Gomez-Zepeda, Méryam Taghi, J. Scherrmann, X. Declèves +1 more
2019Pharmaceutics110 citations Open access
Semantic Scholar
Purification of Mouse Brain Vessels.
A. Boulay, B. Saubaméa, X. Declèves, M. Cohen-Salmon
2015Journal of Visualized Experiments94 citations Open access
Semantic Scholar
Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects.
Eisuke Miyauchi, M. Tachikawa, X. Declèves, Yasuo Uchida +8 more
2016Molecular Pharmaceutics76 citations
Semantic Scholar
Classification of and risk factors for estrogen deprivation pain syndromes related to aromatase inhibitor treatments in women with breast cancer: a prospective multicenter cohort study.
F. Laroche, J. Coste, T. Medkour, P. Cottu +8 more
2014Journal of Pain73 citations Open access
Semantic Scholar
Cannabidiol Increases Proliferation, Migration, Tubulogenesis, and Integrity of Human Brain Endothelial Cells through TRPV2 Activation.
Hui-Long Luo, Elisa Rossi, B. Saubaméa, Stéphanie Chasseigneaux +11 more
2019Molecular Pharmaceutics66 citations
Semantic Scholar
Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity.
S. Mouly, V. Bloch, K. Peoc'h, P. Houzé +9 more
2015British Journal of Clinical Pharmacology66 citations Open access
Semantic Scholar
Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach
C. Lloret-Linares, D. Hirt, C. Bardin, J. Bouillot +7 more
2014Clinical Pharmacokinetics63 citations
Semantic Scholar
Isolation and differential transcriptome of vascular smooth muscle cells and mid-capillary pericytes from the rat brain
Stéphanie Chasseigneaux, Yasmine Moraca, Véronique Cochois-Guégan, A. Boulay +9 more
2018Scientific Reports60 citations Open access
Semantic Scholar
Blood–brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P‐glycoprotein on a novel verapamil influx carrier
H. Chapy, B. Saubaméa, N. Tournier, F. Bourasset +4 more
2016British Journal of Pharmacology56 citations Open access
Semantic Scholar
[18F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model
N. Vignal, S. Cisternino, N. Rizzo‐Padoin, C. San +5 more
2018Molecules44 citations Open access
Semantic Scholar
Functionalized PLA-PEG nanoparticles targeting intestinal transporter PepT1 for oral delivery of acyclovir.
Betty Gourdon, Caroline Chemin, A. Moreau, Thomas Arnauld +4 more
2017International journal of pharmaceutics43 citations
Semantic Scholar
RYGB and Drug Disposition: How to Do Better? Analysis of Pharmacokinetic Studies and Recommendations for Clinical Practice
L. Hachon, X. Declèves, P. Faucher, C. Carette +1 more
2017Obesity Surgery39 citations
Semantic Scholar
Human ABC transporters at blood-CNS interfaces as determinants of CNS drug penetration.
C. Chaves, R. Shawahna, Aude Jacob, J. Scherrmann +1 more
2014Current pharmaceutical design38 citations
Semantic Scholar
Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide
Agnès Dodacki, M. Wortman, B. Saubaméa, Stéphanie Chasseigneaux +8 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Exposure of human cerebral microvascular endothelial cells hCMEC/D3 to laminar shear stress induces vascular protective responses
Nina Choublier, Méryam Taghi, M. Menet, M. Le Gall +12 more
2022Fluids and Barriers of the CNS33 citations Open access
Semantic Scholar
Characterization of the Blood–Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma
C. Chaves, X. Declèves, Méryam Taghi, M. Menet +5 more
2020Pharmaceutics31 citations Open access
Semantic Scholar
Pharmacophore‐based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line
H. Chapy, Laura Goracci, P. Vayer, Y. Parmentier +5 more
2015British Journal of Pharmacology29 citations Open access
Semantic Scholar
Exposure–Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer
Thomas Rodier, A. Puszkiel, E. Cardoso, D. Balakirouchenane +14 more
2022Pharmaceutics28 citations Open access
Semantic Scholar
Megalencephalic leukoencephalopathy with subcortical cysts is a developmental disorder of the gliovascular unit
Alice Gilbert, Xabier Elorza-Vidal, A. Rancillac, Audrey Chagnot +18 more
2021bioRxiv27 citations Open access
Semantic Scholar
A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood‐retinal barrier
H. Chapy, Pascal André, X. Declèves, J. Scherrmann +1 more
2015British Journal of Pharmacology27 citations Open access
Semantic Scholar
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model
S. Dallas, L. Salphati, David Gomez-Zepeda, T. Wanek +20 more
2016Molecular Pharmacology26 citations Open access
Semantic Scholar
Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells
Aude Jacob, S. Potin, B. Saubaméa, D. Crété +4 more
2015Journal of Neurochemistry26 citations
Semantic Scholar
A physiologically based modeling strategy during preclinical CNS drug development.
Kathryn Ball, F. Bouzom, J. Scherrmann, B. Walther +1 more
2014Molecular Pharmaceutics26 citations
Semantic Scholar
Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells.
Hui-Long Luo, M. Gauthier, Xi Tan, C. Landry +7 more
2018Molecular Pharmaceutics24 citations
Semantic Scholar
Oral Morphine Pharmacokinetic in Obesity: The Role of P-Glycoprotein, MRP2, MRP3, UGT2B7, and CYP3A4 Jejunal Contents and Obesity-Associated Biomarkers.
C. Lloret-Linares, Eisuke Miyauchi, Hui-Long Luo, L. Labat +11 more
2016Molecular Pharmaceutics24 citations
Semantic Scholar
An Interspecies Molecular and Functional Study of Organic Cation Transporters at the Blood-Brain Barrier: From Rodents to Humans
C. Chaves, F. Campanelli, H. Chapy, David Gomez-Zepeda +8 more
2020Pharmaceutics23 citations Open access
Semantic Scholar
The Pharmacokinetics of Lithium
C. Couffignal, L. Chevillard, S. El Balkhi, S. Cisternino +1 more
201722 citations
Semantic Scholar
The effect of morbid obesity on morphine glucuronidation
C. Lloret-Linares, Hui-Long Luo, A. Rouquette, L. Labat +7 more
2016Pharmacological Research22 citations
Semantic Scholar
Fasting upregulates the monocarboxylate transporter MCT1 at the rat blood-brain barrier through PPAR δ activation
Stéphanie Chasseigneaux, Véronique Cochois-Guégan, Lucas Lecorgne, Murielle Lochus +12 more
2024Fluids and Barriers of the CNS21 citations Open access
Semantic Scholar
Molecular and Functional Study of Transient Receptor Potential Vanilloid 1-4 at the Rat and Human Blood–Brain Barrier Reveals Interspecies Differences
Hui-Long Luo, B. Saubaméa, Stéphanie Chasseigneaux, V. Cochois +6 more
2020Frontiers in Cell and Developmental Biology21 citations Open access
Semantic Scholar
Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure.
Aude Jacob, S. Potin, H. Chapy, D. Crété +5 more
2015Brain Research21 citations
Semantic Scholar
LC–MS/MS‐based quantification of efflux transporter proteins at the BBB
David Gomez-Zepeda, Méryam Taghi, M. Smirnova, P. Sergent +11 more
2019Journal of Pharmaceutical and Biomedical Analysis20 citations Open access
Semantic Scholar
Effect of Subchronic Intravenous Morphine Infusion and Naloxone-Precipitated Morphine Withdrawal on P-gp and Bcrp at the Rat Blood-Brain Barrier.
C. Chaves, David Gomez-Zepeda, Sylvain Auvity, M. Menet +5 more
2016Journal of Pharmacy and Science20 citations
Semantic Scholar
Diphenhydramine as a selective probe to study H+-antiporter function at the blood–brain barrier: Application to [11C]diphenhydramine positron emission tomography imaging
Sylvain Auvity, H. Chapy, S. Goutal, F. Caillé +5 more
2017Journal of Cerebral Blood Flow and Metabolism19 citations Open access
Semantic Scholar
Usefulness of plasma drug monitoring in severe baclofen poisoning
C. Cleophax, António Gonçalves, C. Chasport, Eugénie de Beaugrenier +3 more
2015Clinical toxicology19 citations
Semantic Scholar
Imaging Probes and Modalities for the Study of Solute Carrier O (SLCO)-Transport Function In Vivo.
S. Marié, S. Cisternino, I. Buvat, X. Declèves +1 more
2017Journal of Pharmacy and Science18 citations Open access
Semantic Scholar
Review of the Existing Translational Pharmacokinetics Modeling Approaches Specific to Monoclonal Antibodies (mAbs) to Support the First-In-Human (FIH) Dose Selection
B. Pasquiers, Salih Benamara, M. Felices, L. Nguyen +1 more
2022International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Report of severe accidental baclofen intoxication in a healthy 4-year-old boy and review of the literature.
C. de Marcellus, S. Le Bot, X. Declèves, F. Baud +2 more
2019Archives de pédiatrie17 citations Open access
Semantic Scholar
Liquid chromatography high resolution mass spectrometry for the determination of baclofen and its metabolites in plasma: Application to therapeutic drug monitoring.
L. Labat, António Gonçalves, A. R. Marques, B. Duretz +2 more
2017Biomedical chromotography17 citations
Semantic Scholar
The role of brain barriers in the neurokinetics and pharmacodynamics of lithium.
Hui-Long Luo, L. Chevillard, F. Bellivier, B. Mégarbane +3 more
2021Pharmacological Research16 citations Open access
Semantic Scholar
Blood–Brain Barrier Dynamic Device with Uniform Shear Stress Distribution for Microscopy and Permeability Measurements
Nina Choublier, Yoann Müller, Loris Gomez Baisac, Jeremy Laedermann +3 more
2021Applied Sciences16 citations Open access
Semantic Scholar
CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content.
C. Lloret-Linares, Y. Daali, C. Abbara, C. Carette +4 more
2019Surgery for Obesity and Related Diseases16 citations Open access
Semantic Scholar
Population pharmacokinetics of oral baclofen at steady‐state in alcoholic‐dependent adult patients
L. Chevillard, N. Sabo, M. Tod, L. Labat +12 more
2018Fundamental & Clinical Pharmacology16 citations
Semantic Scholar
Targeted unlabeled multiple reaction monitoring analysis of cell markers for the study of sample heterogeneity in isolated rat brain cortical microvessels
David Gomez-Zepeda, C. Chaves, Méryam Taghi, P. Sergent +11 more
2017Journal of Neurochemistry15 citations
Semantic Scholar
The use of levothyroxine absorption tests in clinical practice.
P. Caron, X. Declèves
2023Journal of Clinical Endocrinology and Metabolism14 citations
Semantic Scholar
Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
Thibaud Derippe, Sylvain Fouliard, Ibtissam Marchiq, S. Dupouy +5 more
2022Cancer Research Communications14 citations Open access
Semantic Scholar
Glucocorticoids dosing in obese subjects: A systematic review.
J. Delaleu, Alexandre Destère, L. Hachon, X. Declèves +1 more
2019The´rapie (Paris)14 citations
Semantic Scholar
Influence of PLA‐PEG nanoparticles manufacturing process on intestinal transporter PepT1 targeting and oxytocin transport
Betty Gourdon, Caroline Chemin, A. Moreau, Thomas Arnauld +3 more
2018European journal of pharmaceutics and biopharmaceutics14 citations
Semantic Scholar
Morphine and metabolites plasma levels after administration of sustained release morphine in Roux-en-Y gastric bypass subjects versus matched control subjects.
L. Hachon, Rafael Reis, L. Labat, C. Poitou +3 more
2017Surgery for Obesity and Related Diseases14 citations
Semantic Scholar

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