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J. Scherrmann · SciRah

Researcher profile · Semantic Scholar

J. Scherrmann

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J. Scherrmann — researcher profile on SciRah

h-index: 60
Works: 325
Citations: 12K

Most-cited papers

CNS Delivery Via Adsorptive Transcytosis
F. Hérve, N. Ghinea, J. Scherrmann
2008AAPS Journal608 citations Open access
Semantic Scholar
Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.
R. Shawahna, Yasuo Uchida, X. Declèves, S. Ohtsuki +8 more
2011Molecular Pharmaceutics369 citations
Semantic Scholar
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.
S. Ohtsuki, Chiemi Ikeda, Yasuo Uchida, Yumi Sakamoto +8 more
2013Molecular Pharmaceutics218 citations
Semantic Scholar
Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
Sandrine Dauchy, F. Miller, P. Couraud, R. Weaver +5 more
2009Biochemical Pharmacology201 citations
Semantic Scholar
Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2).
N. Tournier, L. Chevillard, B. Mégarbane, S. Pirnay +2 more
2010International Journal of Neuropsychopharmacology124 citations Open access
Semantic Scholar
ABC Transporters at the Blood–Brain Interfaces, Their Study Models, and Drug Delivery Implications in Gliomas
David Gomez-Zepeda, Méryam Taghi, J. Scherrmann, X. Declèves +1 more
2019Pharmaceutics110 citations Open access
Semantic Scholar
ABCG2- and ABCG4-Mediated Efflux of Amyloid-β Peptide 1-40 at the Mouse Blood-Brain Barrier
T. Do, M. Noel-Hudson, S. Ribes, Capucine Besengez +9 more
2012Journal of Alzheimer's Disease101 citations
Semantic Scholar
Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass.
Arnaud Bruyère, X. Declèves, F. Bouzom, Kathryn Ball +8 more
2010Molecular Pharmaceutics99 citations
Semantic Scholar
Interplay of drug metabolizing CYP450 enzymes and ABC transporters in the blood-brain barrier.
X. Declèves, Aude Jacob, S. Yousif, R. Shawahna +2 more
2011Current drug metabolism94 citations
Semantic Scholar
Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects.
Eisuke Miyauchi, M. Tachikawa, X. Declèves, Yasuo Uchida +8 more
2016Molecular Pharmaceutics76 citations
Semantic Scholar
Altered cerebral vascular volumes and solute transport at the blood-brain barriers of two transgenic mouse models of Alzheimer's disease.
T. Do, Wael Alata, Agnès Dodacki, M. Traversy +6 more
2014Neuropharmacology73 citations
Semantic Scholar
Heterogeneity in the Rat Brain Vasculature Revealed by Quantitative Confocal Analysis of Endothelial Barrier Antigen and P-Glycoprotein Expression
B. Saubaméa, Véronique Cochois-Guégan, S. Cisternino, J. Scherrmann
2012Journal of Cerebral Blood Flow and Metabolism72 citations Open access
Semantic Scholar
Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology.
N. Tournier, X. Declèves, B. Saubaméa, J. Scherrmann +1 more
2011Current pharmaceutical design68 citations
Semantic Scholar
Pharmacology of Morphine in Obese Patients
Célia Lloret Linares, X. Declèves, J. Oppert, A. Basdevant +6 more
2009Clinical Pharmacokinetics68 citations
Semantic Scholar
ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders
F. Dutheil, Aude Jacob, Sandrine Dauchy, P. Beaune +3 more
2010Expert Opinion on Drug Metabolism & Toxicology67 citations
Semantic Scholar
Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity.
S. Mouly, V. Bloch, K. Peoc'h, P. Houzé +9 more
2015British Journal of Clinical Pharmacology66 citations Open access
Semantic Scholar
Mechanistic modeling of hepatic transport from cells to whole body: application to napsagatran and fexofenadine.
A. Poirier, C. Funk, J. Scherrmann, T. Lavé
2009Molecular Pharmaceutics65 citations
Semantic Scholar
Effect of a Roux-en-Y Gastric Bypass on the Pharmacokinetics of Oral Morphine Using a Population Approach
C. Lloret-Linares, D. Hirt, C. Bardin, J. Bouillot +7 more
2014Clinical Pharmacokinetics63 citations
Semantic Scholar
Clonidine Transport at the Mouse Blood—Brain Barrier by a New H+ Antiporter that Interacts with Addictive Drugs
Pascal André, M. Debray, J. Scherrmann, S. Cisternino
2009Journal of Cerebral Blood Flow and Metabolism63 citations Open access
Semantic Scholar
Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer’s Disease (3xTg-AD)
T. Do, Agnès Dodacki, Wael Alata, F. Calon +4 more
2015Journal of Alzheimer's Disease60 citations
Semantic Scholar
Development of a physiologically based pharmacokinetic model for the rat central nervous system and determination of an in vitro-in vivo scaling methodology for the blood-brain barrier permeability of two transporter substrates, morphine and oxycodone.
Kathryn Ball, F. Bouzom, J. Scherrmann, B. Walther +1 more
2012Journal of Pharmacy and Science59 citations
Semantic Scholar
Hurdles with using in vitro models to predict human blood-brain barrier drug permeability: a special focus on transporters and metabolizing enzymes.
R. Shawahna, X. Declèves, J. Scherrmann
2012Current drug metabolism59 citations
Semantic Scholar
Effects of Selected OATP and/or ABC Transporter Inhibitors on the Brain and Whole-Body Distribution of Glyburide
N. Tournier, W. Saba, S. Cisternino, M. Peyronneau +8 more
2013AAPS Journal58 citations Open access
Semantic Scholar
Transport of Selected PET Radiotracers by Human P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2): An In Vitro Screening
N. Tournier, H. Valette, M. Peyronneau, W. Saba +6 more
2011Journal of Nuclear Medicine58 citations Open access
Semantic Scholar
Blood–brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P‐glycoprotein on a novel verapamil influx carrier
H. Chapy, B. Saubaméa, N. Tournier, F. Bourasset +4 more
2016British Journal of Pharmacology56 citations Open access
Semantic Scholar
Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood–brain barrier in mice
H. Al-Haddad, S. Cisternino, X. Declèves, N. Tournier +8 more
2012Critical Care Medicine56 citations
Semantic Scholar
Integrated Pharmacokinetic/Pharmacodynamic Model of a Bispecific CD3xCD123 DART Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity
O. Campagne, Audrey Delmas, Sylvain Fouliard, M. Chenel +5 more
2018Clinical Cancer Research55 citations
Semantic Scholar
Carrier-Mediated Cocaine Transport at the Blood-Brain Barrier as a Putative Mechanism in Addiction Liability
H. Chapy, M. Smirnova, Pascal André, J. Schlatter +5 more
2014International Journal of Neuropsychopharmacology52 citations Open access
Semantic Scholar
Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels
Aude Jacob, Anika M. S. Hartz, S. Potin, X. Coumoul +4 more
2011Fluids and Barriers of the CNS51 citations Open access
Semantic Scholar
Induction of P‐glycoprotein and Bcrp at the rat blood–brain barrier following a subchronic morphine treatment is mediated through NMDA/COX‐2 activation
S. Yousif, C. Chaves, S. Potin, I. Margaill +2 more
2012Journal of Neurochemistry48 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Modelling of Drug Penetration Across the Blood–Brain Barrier—Towards a Mechanistic IVIVE-Based Approach
Kathryn Ball, F. Bouzom, J. Scherrmann, B. Walther +1 more
2013AAPS Journal47 citations Open access
Semantic Scholar
Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research
Céline Passeleu-Le Bourdonnec, P. Carrupt, J. Scherrmann, Sophie Martel
2013Pharmaceutical Research45 citations Open access
Semantic Scholar
Coexistence of Passive and Proton Antiporter-Mediated Processes in Nicotine Transport at the Mouse Blood–Brain Barrier
S. Cisternino, H. Chapy, Pascal André, M. Smirnova +2 more
2012AAPS Journal40 citations Open access
Semantic Scholar
Human ABC transporters at blood-CNS interfaces as determinants of CNS drug penetration.
C. Chaves, R. Shawahna, Aude Jacob, J. Scherrmann +1 more
2014Current pharmaceutical design38 citations
Semantic Scholar
Impact of P-glycoprotein at the blood-brain barrier on the uptake of heroin and its main metabolites: behavioral effects and consequences on the transcriptional responses and reinforcing properties
Marianne Seleman, H. Chapy, S. Cisternino, C. Courtin +6 more
2014Psychopharmacology38 citations
Semantic Scholar
Transport of Biogenic Amine Neurotransmitters at the Mouse Blood–Retina and Blood–Brain Barriers by Uptake1 and Uptake2
Pascal André, B. Saubaméa, Véronique Cochois-Guégan, C. Marie-Claire +5 more
2012Journal of Cerebral Blood Flow and Metabolism38 citations Open access
Semantic Scholar
Expression and function of Abcg4 in the mouse blood-brain barrier: role in restricting the brain entry of amyloid-β peptide
Agnès Dodacki, M. Wortman, B. Saubaméa, Stéphanie Chasseigneaux +8 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Placental Transfer of Maraviroc in an Ex Vivo Human Cotyledon Perfusion Model and Influence of ABC Transporter Expression
Cécile Vinot, L. Gavard, Jean-Marc Tréluyer, S. Manceau +7 more
2013Antimicrobial Agents and Chemotherapy37 citations Open access
Semantic Scholar
Transporters in Absorption, Distribution, and Elimination
J. Scherrmann
2009Chemistry and Biodiversity37 citations
Semantic Scholar
ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: influence of spontaneous syncytialization and induction by glucocorticoids.
S. Manceau, C. Giraud, X. Declèves, J. Scherrmann +5 more
2012Placenta34 citations
Semantic Scholar
Is Lockdown Effective in Limiting SARS-CoV-2 Epidemic Progression?—a Cross-Country Comparative Evaluation Using Epidemiokinetic Tools
B. Mégarbane, F. Bourasset, J. Scherrmann
2021Journal of general internal medicine33 citations Open access
Semantic Scholar
Attention-Deficit and Disruptive Behavior Disorders
J. Scherrmann, K. Wolff, Christine A. Franco, M. Potenza +163 more
201433 citations
Semantic Scholar
Expression and induction by dexamethasone of ABC transporters and nuclear receptors in a human T-lymphocyte cell line
S. Manceau, C. Giraud, X. Declèves, F. Batteux +6 more
2012Journal of chemotherapy31 citations
Semantic Scholar
Discrepancies in the P-glycoprotein-Mediated Transport of 18F-MPPF: A Pharmacokinetic Study in Mice and Non-human Primates
N. Tournier, S. Cisternino, M. Peyronneau, S. Goutal +5 more
2012Pharmaceutical Research30 citations
Semantic Scholar
Pharmacophore‐based discovery of inhibitors of a novel drug/proton antiporter in human brain endothelial hCMEC/D3 cell line
H. Chapy, Laura Goracci, P. Vayer, Y. Parmentier +5 more
2015British Journal of Pharmacology29 citations Open access
Semantic Scholar
A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood‐retinal barrier
H. Chapy, Pascal André, X. Declèves, J. Scherrmann +1 more
2015British Journal of Pharmacology27 citations Open access
Semantic Scholar
Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA).
J. Fonsart, M. Menet, M. Debray, D. Hirt +3 more
2009Toxicology and Applied Pharmacology27 citations
Semantic Scholar
Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells
Aude Jacob, S. Potin, B. Saubaméa, D. Crété +4 more
2015Journal of Neurochemistry26 citations
Semantic Scholar
A physiologically based modeling strategy during preclinical CNS drug development.
Kathryn Ball, F. Bouzom, J. Scherrmann, B. Walther +1 more
2014Molecular Pharmaceutics26 citations
Semantic Scholar
Hydroxychloroquine and Azithromycin to Treat Patients With COVID‐19: Both Friends and Foes?
B. Mégarbane, J. Scherrmann
2020Journal of clinical pharmacology24 citations Open access
Semantic Scholar

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X. Declèves — researcher profile on SciRah
S. Cisternino×15
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S. Cisternino — researcher profile on SciRah
N. Tournier×7
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N. Tournier — researcher profile on SciRah
Aude Jacob×6
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Aude Jacob — researcher profile on SciRah

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M. Smirnova — researcher profile on SciRah

F. Bourasset×6

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F. Bourasset — researcher profile on SciRah

B. Saubaméa×6

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B. Saubaméa — researcher profile on SciRah

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H. Chapy — researcher profile on SciRah

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S. Mouly — researcher profile on SciRah

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Pascal André — researcher profile on SciRah

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R. Shawahna — researcher profile on SciRah

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S. Yousif — researcher profile on SciRah