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Sylvain Fouliard · SciRah

Researcher profile · Semantic Scholar

Sylvain Fouliard

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Sylvain Fouliard — researcher profile on SciRah

h-index: 12
Works: 30
Citations: 812

Most-cited papers

Genome-Edited, Donor-derived Allogeneic Anti-CD19 Chimeric Antigen Receptor T-cells in Paediatric and Adult B-Acute Lymphoblastic Leukaemia: Results of Two Phase I Studies
R. Benjamin, Charlotte E. Graham, D. Yallop, A. Jóźwik +25 more
2020The Lancet302 citations Open access
Semantic Scholar
UCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial
R. Benjamin, N. Jain, Marcela V. Maus, N. Boissel +18 more
2022The Lancet Haematology103 citations Open access
Semantic Scholar
Preliminary Data on Safety, Cellular Kinetics and Anti-Leukemic Activity of UCART19, an Allogeneic Anti-CD19 CAR T-Cell Product, in a Pool of Adult and Pediatric Patients with High-Risk CD19+ Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia
R. Benjamin, Charlotte E. Graham, D. Yallop, A. Jóźwik +22 more
2018Blood87 citations
Semantic Scholar
Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm
V. Chelliah, Georgia Lazarou, Sumit Bhatnagar, J. Gibbs +35 more
2020Clinical pharmacology and therapy69 citations Open access
Semantic Scholar
Integrated Pharmacokinetic/Pharmacodynamic Model of a Bispecific CD3xCD123 DART Molecule in Nonhuman Primates: Evaluation of Activity and Impact of Immunogenicity
O. Campagne, Audrey Delmas, Sylvain Fouliard, M. Chenel +5 more
2018Clinical Cancer Research55 citations
Semantic Scholar
Pharmacokinetic/pharmacodynamic modelling-based optimisation of administration schedule for the histone deacetylase inhibitor abexinostat (S78454/PCI-24781) in phase I.
Sylvain Fouliard, R. Robert, A. Jacquet-Bescond, Q. C. du Rieu +8 more
2013European Journal of Cancer30 citations
Semantic Scholar
Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment
Sophie Peigné, F. Bouzom, K. Brendel, C. Gesson +2 more
2015Journal of Pharmacokinetics and Pharmacodynamics19 citations
Semantic Scholar
Clinical Pharmacology and Determinants of Response to UCART19, an Allogeneic Anti-CD19 CAR-T Cell Product, in Adult B-cell Acute Lymphoblastic Leukemia
S. Dupouy, Ibtissam Marchiq, Thibaud Derippe, Maria Almena-Carrasco +13 more
2022Cancer Research Communications18 citations Open access
Semantic Scholar
Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology
Philippe B. Pierrillas, Sylvain Fouliard, M. Chenel, A. Hooker +2 more
2018AAPS Journal18 citations Open access
Semantic Scholar
Pharmacokinetic/Pharmacodynamic modeling of abexinostat-induced thrombocytopenia across different patient populations: application for the determination of the maximum tolerated doses in both lymphoma and solid tumour patients
Quentin Chalret du Rieu, Sylvain Fouliard, M. White-Koning, I. Kloos +2 more
2014Investigational new drugs17 citations
Semantic Scholar
Mechanistic Modeling of the Interplay Between Host Immune System, IL-7 and UCART19 Allogeneic CAR-T Cells in Adult B-cell Acute Lymphoblastic Leukemia
Thibaud Derippe, Sylvain Fouliard, Ibtissam Marchiq, S. Dupouy +5 more
2022Cancer Research Communications14 citations Open access
Semantic Scholar
Model-based approaches for ivabradine development in paediatric population, part II: PK and PK/PD assessment
Sophie Peigné, Sylvain Fouliard, Sophie Decourcelle, M. Chenel
2015Journal of Pharmacokinetics and Pharmacodynamics14 citations
Semantic Scholar
Application of Hematological Toxicity Modeling in Clinical Development of Abexinostat (S-78454, PCI-24781), A New Histone Deacetylase Inhibitor
Quentin Chalret du Rieu, Sylvain Fouliard, A. Jacquet-Bescond, R. Robert +4 more
2013Pharmaceutical Research10 citations
Semantic Scholar
Modeling and simulation of cell populations interaction
Sylvain Fouliard, S. Benhamida, Natacha Lenuzza, F. Xavier
2009Mathematical and computer modelling10 citations Open access
Semantic Scholar
Modeling restoration of gefitinib efficacy by co‐administration of MET inhibitors in an EGFR inhibitor‐resistant NSCLC xenograft model: A tumor‐in‐host DEB‐based approach
E. Tosca, Glenn Gauderat, Sylvain Fouliard, M. Burbridge +2 more
2021CPT: Pharmacometrics & Systems Pharmacology9 citations Open access
Semantic Scholar
Quantitative Analysis of Melanocyte Migration in vitro Based on Automated Cell Tracking under Phase Contrast Microscopy Considering the Combined Influence of Cell Division and Cell-Matrix Interactions
V. Letort, Sylvain Fouliard, G. Letort, Ivan Adanja +5 more
20108 citations Open access
Semantic Scholar
Accelerating robust plausible virtual patient cohort generation by substituting ODE simulations with parameter space mapping
Thibaud Derippe, Sylvain Fouliard, X. Declèves, D. Mager
2022Journal of Pharmacokinetics and Pharmacodynamics7 citations
Semantic Scholar
Influence of the Duration of Intravenous Drug Administration on Tumor Uptake
Sylvain Fouliard, M. Chenel, F. Marcucci
2013Frontiers in Oncology7 citations Open access
Semantic Scholar
The Evolving Role of In Vitro–In Vivo Correlation in Model‐Informed Drug Development: A Multi‐Stakeholder Perspective
M. Chenel, Sylvain Fouliard, Emma Hansson, K. Brendel +4 more
2025CPT: Pharmacometrics & Systems Pharmacology6 citations Open access
Semantic Scholar
Virtual patients inspired by multiomics predict the efficacy of an anti-IFNα mAb in cutaneous lupus
Vincent Hurez, Glenn Gauderat, Perrine Soret, Renee Myers +12 more
2025iScience5 citations Open access
Semantic Scholar
How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example
C. Meyer, Ines Dierick, Glenn Gauderat, J. Langenhorst +5 more
2022Clinical pharmacology and therapy4 citations Open access
Semantic Scholar
Quantitative systems pharmacology modeling of tumor heterogeneity in response to BH3‐mimetics using virtual tumors calibrated with cell viability assays
Thibaud Derippe, Sylvain Fouliard, X. Declèves, Donald E. Mager
2024CPT: Pharmacometrics & Systems Pharmacology1 citations Open access
Semantic Scholar
PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With Microdosing
Chloé Burlot, François Riglet, Mathilde Romagnoli, A. Leconte +3 more
2026CPT: Pharmacometrics & Systems Pharmacology0 citations Open access
Semantic Scholar
PKPD-Based Translational Modeling of Calaspargase Pegol Preclinical Activity in Hepatocellular Carcinoma
Eef Hoeben, V. Madelain, Chayan Acharya, Pierre Barbier Saint Hilaire +3 more
2026European journal of drug metabolism and pharmacokinetics0 citations Open access
Semantic Scholar
Peccary, a metaprogramming open-source R platform to improve pharmacometrics efficiency
Thibaud Derippe, X. Declèves, Sylvain Fouliard
2022F1000Research0 citations Open access
Semantic Scholar
Correction to: Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology
Philippe B. Pierrillas, Sylvain Fouliard, M. Chenel, A. Hooker +2 more
2018AAPS Journal0 citations Open access
Semantic Scholar
In Silico Comparison of Maximum Tolerated Dose Determination in a Phase I Dose-Finding Framework: Application to Hematological Toxicity for a Histone Deacetylase Inhibitor Abexinostat, Co-Administered with Free or Liposomal Doxorubicin in Solid Tumors
C. Vong, Sylvain Fouliard, Quentin Chalret de Rieu, Iona Kloos +2 more
20140 citations
Semantic Scholar
Schema d'administration du n- hydroxy - 4 - {2- [3- (n, n- dimethylaminomethyl) benzofuran- 2 - ylcarbonylamino] ethoxy} benzamide
I. Kloos, R. Robert, A. Jacquet-Bescond, S. Depil +3 more
20120 citations
Semantic Scholar
Abstract A192: PK/PD modeling-based optimization of administration schedule for the histone deacetylase inhibitor (HDACi) S78454/PCI-24781 in phase I.
R. Robert, A. Jacquet-Bescond, M. Chenel, Sylvain Fouliard +7 more
20110 citations
Semantic Scholar
Optimal design and QT-prolongation detection in oncology studies
Sylvain Fouliard, M. Chenel
20090 citations
Semantic Scholar

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