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Y. Daali · SciRah

Researcher profile · Semantic Scholar

Y. Daali

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Y. Daali — researcher profile on SciRah

h-index: 40
Works: 198
Citations: 5,719

Most-cited papers

Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy.
A. Darwich, T. Polasek, J. Aronson, K. Ogungbenro +9 more
2020Annual Review of Pharmacology and Toxicology193 citations Open access
Semantic Scholar
Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice.
Julia Wagner, Dorothée Gößl, Natasha Ustyanovska, Meng-Yao Xiong +10 more
2021ACS Nano157 citations Open access
Semantic Scholar
Impact of Acute Inflammation on Cytochromes P450 Activity Assessed by the Geneva Cocktail
Camille Lenoir, Y. Daali, V. Rollason, F. Curtin +8 more
2020Clinical pharmacology and therapy89 citations Open access
Semantic Scholar
Dynamics of active pharmaceutical ingredients loads in a Swiss university hospital wastewaters and prediction of the related environmental risk for the aquatic ecosystems.
S. Daouk, N. Chèvre, N. Vernaz, C. Widmer +2 more
2016Science of the Total Environment88 citations
Semantic Scholar
Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites
N. Marsousi, Y. Daali, P. Fontana, J. Reny +5 more
2018Clinical Pharmacokinetics67 citations Open access
Semantic Scholar
Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine.
N. Marsousi, J. Desmeules, S. Rudaz, Y. Daali
2017Journal of Pharmacy and Science65 citations Open access
Semantic Scholar
Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug–Drug Interactions
F. Storelli, A. Matthey, S. Lenglet, A. Thomas +2 more
2018Clinical pharmacology and therapy64 citations Open access
Semantic Scholar
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis.
T. Seredenina, Z. Nayernia, S. Sorce, G. Maghzal +12 more
2016Free Radical Biology & Medicine57 citations Open access
Semantic Scholar
Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends
Kenza Abouir, C. Samer, Y. Gloor, J. Desmeules +1 more
2021Frontiers in Pharmacology52 citations Open access
Semantic Scholar
Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches
G. Magliocco, A. Thomas, J. Desmeules, Y. Daali
2019Clinical Pharmacokinetics51 citations Open access
Semantic Scholar
Evaluation of Mutual Drug–Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method
M. Bosilkovska, C. Samer, J. Déglon, A. Thomas +3 more
2016Basic & Clinical Pharmacology & Toxicology50 citations Open access
Semantic Scholar
Impact of SARS‐CoV‐2 Infection (COVID‐19) on Cytochromes P450 Activity Assessed by the Geneva Cocktail
Camille Lenoir, J. Terrier, Y. Gloor, F. Curtin +5 more
2021Clinical pharmacology and therapy49 citations Open access
Semantic Scholar
Complex Drug–Drug–Gene–Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives
F. Storelli, C. Samer, J. Reny, J. Desmeules +1 more
2018Clinical Pharmacokinetics44 citations Open access
Semantic Scholar
The tyrosine kinase inhibitor nilotinib inhibits SARS‐CoV‐2 in vitro
V. Cagno, G. Magliocco, C. Tapparel, Y. Daali
2020Basic & Clinical Pharmacology & Toxicology42 citations Open access
Semantic Scholar
Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity
G. Magliocco, J. Desmeules, A. Matthey, L. Quirós-Guerrero +8 more
2021British Journal of Pharmacology39 citations Open access
Semantic Scholar
Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach
N. Marsousi, C. Samer, P. Fontana, J.-L. Reny +3 more
2016Clinical pharmacology and therapy39 citations Open access
Semantic Scholar
Prediction of drug‐drug interactions using physiologically‐based pharmacokinetic models of CYP450 modulators included in Simcyp software
N. Marsousi, J. Desmeules, S. Rudaz, Y. Daali
2018Biopharmaceutics & drug disposition38 citations Open access
Semantic Scholar
Liquid Biopsy for Patient Characterization in Cardiovascular Disease: Verification against Markers of Cytochrome P450 and P‐Glycoprotein Activities
B. Achour, P. Gosselin, Jean Terrier, Y. Gloor +5 more
2022Clinical pharmacology and therapy35 citations Open access
Semantic Scholar
The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesia
William T. Ralvenius, Mario A. Acuña, D. Benke, A. Matthey +5 more
2016Neuropharmacology31 citations Open access
Semantic Scholar
Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP‐glucuronosyltransferases
Stéphanie Romand, D. Spaggiari, N. Marsousi, C. Samer +3 more
2017Journal of Pharmaceutical and Biomedical Analysis28 citations Open access
Semantic Scholar
Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting
Camille Lenoir, Jean Terrier, Y. Gloor, P. Gosselin +6 more
2022Journal of Personalized Medicine27 citations Open access
Semantic Scholar
Drug metabolic enzyme genotype-phenotype discrepancy: High phenoconversion rate in patients treated with antidepressants.
Y. Gloor, C. Lloret-Linares, M. Bosilkovska, N. Perroud +5 more
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie27 citations Open access
Semantic Scholar
CYP450 Genotype—Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting
Kuntheavy Ing Lorenzini, J. Desmeules, V. Rollason, Stéphane Bertin +3 more
2021Frontiers in Pharmacology24 citations Open access
Semantic Scholar
Hepatocyte Concentrations of Indocyanine Green Reflect Transfer Rates Across Membrane Transporters
Fabien Cusin, Liliana Fernandes Azevedo, Pierre Bonnaventure, J. Desmeules +2 more
2017Basic & Clinical Pharmacology & Toxicology24 citations
Semantic Scholar
Precision dosing of intravenous busulfan in pediatric hematopoietic stem cell transplantation: Results from a multicenter population pharmacokinetic study
Khalil Ben Hassine, T. Nava, Y. Théorêt, C. Nath +9 more
2021CPT: Pharmacometrics & Systems Pharmacology23 citations Open access
Semantic Scholar
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment
Marloes Zoetemelk, George Ramzy, M. Rausch, T. Koessler +19 more
2020Molecular Oncology23 citations Open access
Semantic Scholar
Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS.
G. Magliocco, F. Le Bloc'h, A. Thomas, J. Desmeules +1 more
2021Journal of chromatography. B, Analytical technologies in the biomedical and life sciences22 citations Open access
Semantic Scholar
Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics
Camille Lenoir, Amine Niederer, V. Rollason, J. Desmeules +2 more
2021CPT: Pharmacometrics & Systems Pharmacology20 citations Open access
Semantic Scholar
Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins
V. Rollason, M. Mouterde, Y. Daali, Martina Čížková +16 more
2020Drug Safety20 citations Open access
Semantic Scholar
Cannabinoids for behavioral symptoms in severe dementia: Safety and feasibility in a long-term pilot observational study in nineteen patients
S. Pautex, F. Bianchi, Y. Daali, M. Augsburger +5 more
2022Frontiers in Aging Neuroscience19 citations Open access
Semantic Scholar
Frequency of Important CYP450 Enzyme Gene Polymorphisms in the Iranian Population in Comparison with Other Major Populations: A Comprehensive Review of the Human Data
Navid Neyshaburinezhad, Hengameh Ghasim, M. Rouini, Y. Daali +1 more
2021Journal of Personalized Medicine19 citations Open access
Semantic Scholar
Physiologically‐Based Pharmacokinetic Modeling for the Prediction of CYP2D6‐Mediated Gene–Drug–Drug Interactions
F. Storelli, J. Desmeules, Y. Daali
2019CPT: Pharmacometrics & Systems Pharmacology19 citations Open access
Semantic Scholar
Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of life
A. Wilhelm-Bals, C. Combescure, H. Chehade, Y. Daali +1 more
2019Pediatric nephrology (Berlin, West)19 citations Open access
Semantic Scholar
An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposure.
D. Spaggiari, Y. Daali, S. Rudaz
2016Toxicology and Applied Pharmacology19 citations Open access
Semantic Scholar
Is pain temporary and glory for ever? Detection of tramadol using dried blood spot in cycling competitions.
O. Salamin, A. Garcia, Víctor González-Ruiz, Francesca Rossi +6 more
2020Drug Testing and Analysis17 citations Open access
Semantic Scholar
CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver content.
C. Lloret-Linares, Y. Daali, C. Abbara, C. Carette +4 more
2019Surgery for Obesity and Related Diseases16 citations Open access
Semantic Scholar
Perioperative intravenous low‐dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo‐controlled study
C. Czarnetzki, J. Desmeules, E. Tessitore, A. Faundez +6 more
2019European Journal of Pain15 citations Open access
Semantic Scholar
Genotype‐sensitive reversible and time‐dependent CYP2D6 inhibition in human liver microsomes
F. Storelli, J. Desmeules, Y. Daali
2018Basic & Clinical Pharmacology & Toxicology15 citations Open access
Semantic Scholar
Comparing dried blood spots and plasma concentrations for busulfan therapeutic drug monitoring in children.
Ana Dilo, Y. Daali, J. Desmeules, Y. Chalandon +2 more
2020Therapeutic Drug Monitoring14 citations Open access
Semantic Scholar
Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine‐3‐glucuronide and morphine‐6‐glucuronide in human astrocytes
V. Dozio, Y. Daali, J. Desmeules, Jean-Charles Sanchez
2020Journal of Neuroscience Research14 citations Open access
Semantic Scholar
Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study☆
C. Lloret-Linares, V. Rollason, K. I. Lorenzini, C. Samer +5 more
2017Pharmacological Research14 citations Open access
Semantic Scholar
Pharmacogenomics of Oral Antithrombotic Drugs.
F. Storelli, Y. Daali, J. Desmeules, J. Reny +1 more
2016Current pharmaceutical design14 citations Open access
Semantic Scholar
Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting.
C. Lloret-Linares, M. Bosilkovska, Y. Daali, M. Gex-fabry +8 more
2018Journal of Clinical Psychiatry13 citations Open access
Semantic Scholar
Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus).
Suzanne Osorio-Lujan, W. Habre, Y. Daali, Zhao-Xing Pan +1 more
2017Veterinary Anaesthesia and Analgesia13 citations
Semantic Scholar
Impact of Obesity and Bariatric Surgery on Metabolic Enzymes and P-Glycoprotein Activity Using the Geneva Cocktail Approach
Hengameh Ghasim, M. Rouini, Saeed Safari, F. Larti +6 more
2023Journal of Personalized Medicine12 citations Open access
Semantic Scholar
Population Pharmacokinetic Models for Direct Oral Anticoagulants: A Systematic Review and Clinical Appraisal Using Exposure Simulation
Jean Terrier, Frédéric Gaspar, M. Guidi, P. Fontana +3 more
2022Clinical pharmacology and therapy12 citations Open access
Semantic Scholar
The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker?
G. Magliocco, J. Desmeules, M. Bosilkovska, A. Thomas +1 more
2021Journal of Personalized Medicine11 citations Open access
Semantic Scholar
Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study
V. Rollason, C. Lloret-Linares, K. I. Lorenzini, Y. Daali +5 more
2020Journal of Personalized Medicine11 citations Open access
Semantic Scholar
Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling
G. Magliocco, F. Rodieux, J. Desmeules, C. Samer +1 more
2019Pediatric Research11 citations Open access
Semantic Scholar
Apixaban and rivaroxaban's physiologically‐based pharmacokinetic model validation in hospitalized patients: A first step for larger use of a priori modeling approach at bed side
Jean Terrier, Frédéric Gaspar, Pauline Gosselin, Olivier Raboud +7 more
2023CPT: Pharmacometrics & Systems Pharmacology10 citations Open access
Semantic Scholar

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