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E. Dueber · SciRah

Researcher profile · Semantic Scholar

E. Dueber

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E. Dueber — researcher profile on SciRah

h-index: 18
Works: 35
Citations: 3,790

Most-cited papers

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
R. Aglietti, A. Estevez, Aaron Gupta, Monica L Gonzalez Ramirez +5 more
2016Proceedings of the National Academy of Sciences of the United States of America836 citations Open access
Semantic Scholar
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
I. Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto +23 more
2011Nature786 citations
Semantic Scholar
c‐IAP1 and UbcH5 promote K11‐linked polyubiquitination of RIP1 in TNF signalling
Jasmin N. Dynek, Tatiana Goncharov, E. Dueber, A. Fedorova +7 more
2010EMBO Journal365 citations Open access
Semantic Scholar
Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions.
R. Aglietti, E. Dueber
2017Trends in immunology356 citations
Semantic Scholar
Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation
Xiao-Lei Ma, E. Helgason, Q. Phung, C. Quan +5 more
2012Proceedings of the National Academy of Sciences of the United States of America250 citations Open access
Semantic Scholar
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
I. Wertz, K. Newton, D. Seshasayee, Saritha Kusam +30 more
2015Nature244 citations
Semantic Scholar
Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination
E. Dueber, A. Schoeffler, A. Lingel, J. Elliott +11 more
2011Science229 citations
Semantic Scholar
Recent insights into the complexity of Tank‐binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
E. Helgason, Q. Phung, E. Dueber
2013FEBS Letters184 citations Open access
Semantic Scholar
Targeted degradation via direct 26S proteasome recruitment
C. Bashore, Sumit Prakash, Matthew C. Johnson, Ryan J. Conrad +21 more
2022Nature Chemical Biology94 citations Open access
Semantic Scholar
Preparation of distinct ubiquitin chain reagents of high purity and yield.
Ken C. Dong, E. Helgason, Christine Yu, L. Phu +8 more
2011Structure93 citations Open access
Semantic Scholar
Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Jianping Yin, A. Schoeffler, Katherine E. Wickliffe, K. Newton +3 more
2015Structure72 citations Open access
Semantic Scholar
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449).
Anthony M. Giannetti, H. Wong, G. J. Dijkgraaf, E. Dueber +7 more
2011Journal of Medicinal Chemistry65 citations Open access
Semantic Scholar
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation
M. Holliday, Axel Witt, Alejandro Rodriguez Gama, Benjamin T. Walters +5 more
2019Nature Communications44 citations Open access
Semantic Scholar
c-IAP 1 and UbcH 5 promote K 11-linked polyubiquitination of RIP 1 in TNF signaling
Jasmin N. Dynek, E. Dueber, A. Fedorova, A. Izrael-Tomasevic +7 more
201032 citations
Semantic Scholar
Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
A. Özen, L. Rougé, C. Bashore, B. R. Hearn +2 more
2018Structure31 citations Open access
Semantic Scholar
Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine.
C. Bashore, P. Jaishankar, N. Skelton, J. Fuhrmann +4 more
2020ACS Chemical Biology26 citations Open access
Semantic Scholar
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
W. den Besten, K. Verma, Sayumi Yamazoe, N. Blaquiere +12 more
2021Journal of the American Chemical Society19 citations
Semantic Scholar
A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
M. Steffek, E. Helgason, N. Popovych, L. Rougé +22 more
2022Biochemistry18 citations Open access
Semantic Scholar
Internal motions prime cIAP1 for rapid activation
Aaron H. Phillips, A. Schoeffler, T. Matsui, T. Weiss +5 more
2014Nature Structural &Molecular Biology17 citations Open access
Semantic Scholar
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9
M. Holliday, R. Ferrao, Gladys de Leon Boenig, A. Estevez +4 more
2018Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Constitutive protein degradation induces acute cell death via proteolysis products
Si-Han Chen, Sumit Prakash, E. Helgason, Caroline L. Gilchrist +11 more
2023bioRxiv6 citations Open access
Semantic Scholar
Discovery and characterization of potent macrocycle inhibitors of ubiquitin-specific protease-7.
Rafael Miranda, Francesca Anson, Shannon T. Smith, M. Ultsch +7 more
2025Structure4 citations Open access
Semantic Scholar
Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays
A. Schoeffler, E. Helgason, N. Popovych, E. Dueber
2021Biophysics Reports3 citations Open access
Semantic Scholar
Helical assembly of the CARD9 CARD
M. Holliday, A. Rohou, C. Arthur, E. Dueber +1 more
20193 citations Open access
Semantic Scholar
Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
I. Wertz, K. Newton, D. Seshasayee, Saritha Kusam +30 more
2016Nature3 citations Open access
Semantic Scholar
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
I. Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto +23 more
2011Nature3 citations Open access
Semantic Scholar
N-tert-Butoxycarbonyl-N-(2-(tritylthio)ethoxy)glycine as a Building Block for Peptide Ubiquitination
Lingling Peng, E. Helgason, Rafael Miranda, Jeffrey Y. K. Tom +3 more
2024Bioconjugate chemistry2 citations Open access
Semantic Scholar
Erratum: Diagnosing and mitigating method-based avidity artifacts that confound polyubiquitin-binding assays.
A. Schoeffler, E. Helgason, N. Popovych, E. Dueber
2022Biophysics Reports1 citations Open access
Semantic Scholar
Thoughts for the future
Lona M. Alkhalaf, C. Arrowsmith, E. Balskus, Giovanna Bergamini +45 more
2024Nature Chemical Biology0 citations
Semantic Scholar
NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil
M. Holliday, W. Fairbrother, E. Dueber
20190 citations
Semantic Scholar
NMR solution structure of the CARD9 CARD bound to zinc
M. Holliday, E. Dueber, W. Fairbrother
20180 citations
Semantic Scholar
NMR solution structure of the CARD9 CARD
M. Holliday, E. Dueber, W. Fairbrother
20180 citations
Semantic Scholar
Structure of BX-795 Complexed with Human TBK1 Kinase Domain Phosphorylated on Ser172
X. Ma, E. Helgason, Q. Phung, C.-L. Quan +5 more
20120 citations
Semantic Scholar
Structure of BX-795 Complexed with Unphosphorylated Human TBK1 Kinase-ULD Domain
X. Ma, E. Helgason, Q. Phung, C. Quan +5 more
20120 citations
Semantic Scholar
IAP antagonist-induced conformational change in cIAP1 promotes E3 ligase activation via dimerization
E. Dueber, A. Schoeffler, A. Lingel, M. Elliott +11 more
20110 citations
Semantic Scholar

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