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D. Seshasayee · SciRah

Researcher profile · Semantic Scholar

D. Seshasayee

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D. Seshasayee — researcher profile on SciRah

h-index: 29
Works: 64
Citations: 4,614

Most-cited papers

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
N. Kayagaki, Minhong Yan, D. Seshasayee, Hua Wang +8 more
2002Immunity527 citations Open access
Semantic Scholar
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor.
D. Seshasayee, P. Valdez, Minhong Yan, V. Dixit +2 more
2003Immunity447 citations Open access
Semantic Scholar
Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus
Alexander R. Abbas, Kristen Wolslegel, D. Seshasayee, Z. Modrusan +1 more
2009PLoS ONE425 citations Open access
Semantic Scholar
Loss of the tumor suppressor BAP1 causes myeloid transformation
A. Dey, D. Seshasayee, R. Noubade, D. French +23 more
2012Science424 citations Open access
Semantic Scholar
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
I. Wertz, K. Newton, D. Seshasayee, Saritha Kusam +30 more
2015Nature244 citations
Semantic Scholar
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
D. Seshasayee, Wyne P. Lee, Mei-Juan Zhou, Jean Shu +17 more
2007Journal of Clinical Investigation215 citations Open access
Semantic Scholar
Antibody targeting of E3 ubiquitin ligases for receptor degradation
Hadir Marei, Wen-Ting K. Tsai, Y. Kee, Karen Ruiz +34 more
2022Nature213 citations Open access
Semantic Scholar
APRIL-Deficient Mice Have Normal Immune System Development
E. Varfolomeev, F. Kischkel, F. Martin, D. Seshasayee +9 more
2004Molecular and Cellular Biology210 citations Open access
Semantic Scholar
Monoclonal antibody targeting the β-barrel assembly machine of Escherichia coli is bactericidal
K. M. Storek, Marcy R. Auerbach, Han-Duo Shi, N. Garcia +14 more
2018Proceedings of the National Academy of Sciences of the United States of America160 citations Open access
Semantic Scholar
Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
N. Kayagaki, I. Stowe, K. Alegre, I. Deshpande +25 more
2023Nature154 citations Open access
Semantic Scholar
Massively parallel single-cell B-cell receptor sequencing enables rapid discovery of diverse antigen-reactive antibodies
Leonard D. Goldstein, Y. Chen, Jia Wu, Subhra Chaudhuri +13 more
2019Communications Biology148 citations Open access
Semantic Scholar
Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis
Chia-Lin Hsu, Wei-Yu Lin, D. Seshasayee, Yung-Hsiang Chen +19 more
2012Science137 citations
Semantic Scholar
Functional interaction of GATA1 with erythroid Krüppel-like factor and Sp1 at defined erythroid promoters.
Richard C. Gregory, D. J. Taxman, D. Seshasayee, M. Kensinger +2 more
1996Blood135 citations
Semantic Scholar
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation
D. Choy, D. Hsu, D. Seshasayee, M. Fung +4 more
2012Journal of Allergy and Clinical Immunology124 citations Open access
Semantic Scholar
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Tianhe Sun, Zhiyu Huang, Wei-Ching Liang, Jianping Yin +31 more
2021Science Translational Medicine119 citations Open access
Semantic Scholar
Structure of the core human NADPH oxidase NOX2
S. Noreng, Naruhisa Ota, Yong-Lian Sun, H. Ho +12 more
2022Nature Communications101 citations Open access
Semantic Scholar
A Novel in Vivo Role for Osteoprotegerin Ligand in Activation of Monocyte Effector Function and Inflammatory Response*
D. Seshasayee, Hua Wang, Wyne P. Lee, P. Gribling +4 more
2004Journal of Biological Chemistry84 citations Open access
Semantic Scholar
A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys.
Y. Vugmeyster, D. Seshasayee, Wesley S. Chang, Anahid Storn +13 more
2006American Journal of Pathology83 citations Open access
Semantic Scholar
NTB-A, a New Activating Receptor in T Cells That Regulates Autoimmune Disease*
P. Valdez, Hua Wang, D. Seshasayee, M. van Lookeren Campagne +3 more
2004Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.
Wei-Yu Lin, Qian Gong, D. Seshasayee, Zhonghua Lin +21 more
2007Blood62 citations
Semantic Scholar
Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus
Wei-Yu Lin, D. Seshasayee, Wyne P. Lee, P. Caplazi +9 more
2014Arthritis & Rheumatology53 citations Open access
Semantic Scholar
GATA-1 Dominantly Activates a Program of Erythroid Gene Expression in Factor-Dependent Myeloid FDCW2 Cells
D. Seshasayee, Peter C. W. Gaines, D. Wojchowski
1998Molecular and Cellular Biology51 citations Open access
Semantic Scholar
GATA-1- and FOG-dependent Activation of Megakaryocytic αIIB Gene Expression*
Peter C. W. Gaines, Justin N. Geiger, G. Knudsen, D. Seshasayee +1 more
2000Journal of Biological Chemistry46 citations Open access
Semantic Scholar
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
R. Vij, Zhonghua Lin, Nancy Chiang, Jean-Michel Vernes +21 more
2018Scientific Reports34 citations Open access
Semantic Scholar
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes
Teresita L. Arenzana, Steve Lianoglou, A. Seki, Celine Eidenschenk +19 more
2018Science immunology32 citations Open access
Semantic Scholar
Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate
Kimberly K. Kajihara, Homer Pantua, Hilda Hernandez-Barry, Meredith Hazen +19 more
2021mBio31 citations Open access
Semantic Scholar
Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD
K. M. Storek, Joyce Chan, R. Vij, Nancy Chiang +18 more
2019eLife31 citations Open access
Semantic Scholar
In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells
Zhonghua Lin, Nancy Chiang, Ning Chai, D. Seshasayee +4 more
2014Nature Protocols29 citations
Semantic Scholar
Intron 1 Elements Promote Erythroid-specific GATA-1 Gene Expression*
D. Seshasayee, Justin N. Geiger, Peter C. W. Gaines, D. Wojchowski
2000Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters
Richard C. Gregory, D. J. Taxman, D. Seshasayee, M. Kensinger +2 more
199629 citations
Semantic Scholar
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity
Aurélie Hérault, Judy Mak, Josefa Dela Cruz-Chuh, Michael Dillon +25 more
2024Cancer Immunology and Immunotherapy24 citations
Semantic Scholar
Development of an ^18F-labeled anti-human CD8 VHH for same-day immunoPET imaging
S. Sriraman, C. Davies, H. Gill, J. Kiefer +12 more
2022European Journal of Nuclear Medicine and Molecular Imaging23 citations
Semantic Scholar
Immune repertoire mining for rapid affinity optimization of mouse monoclonal antibodies
Yi-Chun Hsiao, Yonglei Shang, D. Dicara, Angie Yee +10 more
2019mAbs21 citations Open access
Semantic Scholar
The Adaptor Protein Sh2d3c Is Critical for Marginal Zone B Cell Development and Function
Amin Al-Shami, C. Wilkins, J. Crisostomo, D. Seshasayee +5 more
2010Journal of Immunology16 citations
Semantic Scholar
Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
Josefa Dela Cruz-Chuh, M. Go, Yvonne M. Chen, Jun Guo +23 more
2020mAbs15 citations Open access
Semantic Scholar
Extracellular BMP1 is the major proteinase for C-terminal proteolysis of type I procollagen in lung fibroblasts.
E. N'Diaye, R. Cook, Hua Wang, Ping Wu +13 more
2020American Journal of Physiology - Cell Physiology15 citations
Semantic Scholar
Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease.
R. Brendza, Xiaoying Gao, K. Stark, Han Lin +16 more
2022Neurobiology of Disease11 citations Open access
Semantic Scholar
Restricted epitope specificity determined by variable region germline segment pairing in rodent antibody repertoires
Yi-Chun Hsiao, Y. Chen, Leonard D. Goldstein, Jia Wu +9 more
2020mAbs10 citations Open access
Semantic Scholar
Analysis of the effect of promoter type and skin pretreatment on antigen expression and antibody response after gene gun-based immunization
R. Vij, Zhonghua Lin, Kellen Schneider, D. Seshasayee +1 more
2018PLoS ONE8 citations Open access
Semantic Scholar
Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining
Yi-Chun Hsiao, H. Wallweber, R. Alberstein, Zhong-Hua Lin +11 more
2024Nature Communications7 citations Open access
Semantic Scholar
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development
Elaine Mai, Joyce Chan, L. Goon, Braeden K. Ego +14 more
2021Journal of Translational Medicine7 citations Open access
Semantic Scholar
A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies
R. Vij, Zhonghua Lin, Nancy Chiang, Jean-Michel Vernes +21 more
2018Scientific Reports6 citations Open access
Semantic Scholar
Erratum: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
I. Wertz, K. Newton, D. Seshasayee, Saritha Kusam +30 more
2016Nature3 citations Open access
Semantic Scholar
A Co-culture Cell-Based Reporter Assay for Quantitative Measurement of Integrin αvβ8–Mediated Activation of Latent TGF-β1
Jianhuan Zhang, Minh Thai, Matthieu Masureel, Cecilia Chiu +5 more
2026bioRxiv1 citations Open access
Semantic Scholar
Blocking OX40L Function Inhibits TSLP-Induced Atopic Disease In Lung And Skin (37.11)
D. Seshasayee, Mei-Juan Zhou, Jean Shu, Eric Suto +6 more
2007Journal of Immunology1 citations
Semantic Scholar
A Novel in vivo Role For OPGL in Activation Of Monocyte Effector Function and Inflammatory Response
D. Seshasayee, Hua Wang, Wyne P. Lee, P. Gribling +4 more
20041 citations
Semantic Scholar
A modular platform for Sterically Masked Activated Cytokines (SMACks)
T. Morgenstern, Naruhisa Ota, Zhonghua Lin, Laura M. Lechermann +9 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
TREM1 signaling amplifies neutrophil-mediated inflammation in inflammatory bowel disease
Warrison A. Andrade, Hao Xu, Yutian Peng, Zhiyuan Yao +20 more
2026Nature Communications0 citations Open access
Semantic Scholar
A single MHCII neoepitope mRNA vaccine elicits CD4 T- and B- cell responses promoting endogenous CD8 anti-tumor immunity
A. Capietto, Camille-Charlotte Balança, Romain Bouziat, Thomas D. Wu +37 more
2025bioRxiv0 citations Open access
Semantic Scholar
Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury
N. Kayagaki, I. Stowe, K. Alegre, I. Deshpande +25 more
2025Nature0 citations
Semantic Scholar

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