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M. Holliday · SciRah

Researcher profile · Semantic Scholar

M. Holliday

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M. Holliday — researcher profile on SciRah

h-index: 16
Works: 39
Citations: 1,139

Most-cited papers

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.
Simon Schenk, C. McCurdy, A. Philp, Mark Z. Chen +5 more
2011Journal of Clinical Investigation197 citations Open access
Semantic Scholar
Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity
Marie-Eve Lalonde, N. Avvakumov, K. Glass, France-Hélène Joncas +10 more
2013Genes & Development174 citations Open access
Semantic Scholar
Dynamical network of residue–residue contacts reveals coupled allosteric effects in recognition, catalysis, and mutation
U. Doshi, M. Holliday, E. Eisenmesser, D. Hamelberg
2016Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Kα inhibitor that decouples anti-tumor activity from hyperinsulinemia
A. Varkaris, Ermira Pazolli, Hakan Gunaydin, Qi Wang +48 more
2023Cancer Discovery74 citations Open access
Semantic Scholar
Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism
C. Camilloni, A. B. Sahakyan, M. Holliday, N. Isern +3 more
2014Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Networks of Dynamic Allostery Regulate Enzyme Function
M. Holliday, C. Camilloni, G. Armstrong, M. Vendruscolo +1 more
2017Structure70 citations Open access
Semantic Scholar
Attenuated Pik3r1 Expression Prevents Insulin Resistance and Adipose Tissue Macrophage Accumulation in Diet-Induced Obese Mice
C. McCurdy, Simon Schenk, M. Holliday, A. Philp +6 more
2012Diabetes63 citations Open access
Semantic Scholar
Allosteric Inhibitors of the Eya2 Phosphatase Are Selective and Inhibit Eya2-mediated Cell Migration*
Aaron B. Krueger, David J. Drasin, W. Lea, A. Patrick +16 more
2014Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B
K. Bahmed, Curtis J. Henry, M. Holliday, J. Redzic +6 more
2012Cancer Cell International46 citations Open access
Semantic Scholar
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation
M. Holliday, Axel Witt, Alejandro Rodriguez Gama, Benjamin T. Walters +5 more
2019Nature Communications44 citations Open access
Semantic Scholar
The dynamics of interleukin‐8 and its interaction with human CXC receptor I peptide
Agnieszka A. Kendrick, M. Holliday, Nancy G. Isern, Fengli Zhang +5 more
2014Protein Science33 citations Open access
Semantic Scholar
Characterisation of wood combustion and emission under varying moisture contents using multiple imaging techniques
Yu-Feng Lai, Xuan-Qi Liu, Matthew Davies, Callum Fisk +4 more
2024Fuel32 citations Open access
Semantic Scholar
Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro
Ying-Chih Chi, Jeremy T. Rahkola, Agnieszka A. Kendrick, M. Holliday +4 more
2017Protein Science23 citations Open access
Semantic Scholar
Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures
M. Holliday, C. Camilloni, G. Armstrong, N. Isern +3 more
2015Biochemistry20 citations Open access
Semantic Scholar
A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands.
M. Steffek, E. Helgason, N. Popovych, L. Rougé +22 more
2022Biochemistry18 citations Open access
Semantic Scholar
Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif
M. Ultsch, M. Holliday, S. Gerhardy, P. Moran +7 more
2021Communications Biology18 citations Open access
Semantic Scholar
Determination of the Full Catalytic Cycle among Multiple Cyclophilin Family Members and Limitations on the Application of CPMG-RD in Reversible Catalytic Systems
M. Holliday, G. Armstrong, E. Eisenmesser
2015Biochemistry13 citations Open access
Semantic Scholar
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9
M. Holliday, R. Ferrao, Gladys de Leon Boenig, A. Estevez +4 more
2018Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Nanoscale Direct-to-Biology Optimization of Cdk2 Inhibitors.
James L. Douthwaite, Damian Houde, E. Pardo, Mark Moran +16 more
2026Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
Hydrogen/Deuterium Exchange and Protein Oxidative Footprinting with Mass Spectrometry Collectively Discriminate the Binding of Small-Molecule Therapeutics to Bcl-2
Yan Sun, Damian Houde, Roxana E. Iacob, J. Baird +5 more
2025Analytical Chemistry5 citations Open access
Semantic Scholar
Inherent dynamics within the Crimean‐Congo Hemorrhagic fever virus protease are localized to the same region as substrate interactions
E. Eisenmesser, G. Capodagli, G. Armstrong, M. Holliday +3 more
2015Protein Science5 citations Open access
Semantic Scholar
1H, 13C, and 15N backbone and side chain resonance assignments of thermophilic Geobacillus kaustophilus cyclophilin-A
M. Holliday, Fengli Zhang, N. Isern, G. Armstrong +1 more
2012Biomolecular NMR Assignments4 citations Open access
Semantic Scholar
Helical assembly of the CARD9 CARD
M. Holliday, A. Rohou, C. Arthur, E. Dueber +1 more
20193 citations Open access
Semantic Scholar
First bromo-adjacent homology (BAH) domain of human Polybromo-1 (PBRM1)
T. Petojevic, M. Holliday, W. Fairbrother, A. Cochran
20201 citations
Semantic Scholar
Measurement and Characterization of Hydrogen-Deuterium Exchange Chemistry Using Relaxation Dispersion NMR Spectroscopy.
Gennady Khirich, M. Holliday, Jasper C. Lin, Aditya Nandy
2018Journal of Physical Chemistry B1 citations
Semantic Scholar
Abstract 887: Novel role of CD147 in chemoresistance in pancreatic cancer.
K. Bahmed, M. Holliday, Agnieszka A. Kendrick, E. Eisenmesser
20131 citations
Semantic Scholar
Cryptic small-molecule binding sites in the ARID1B DNA-binding domain.
C. Carbone, Heike Schönherr, Victor Y. Zhao, Levi Pierce +8 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
ApoL1 N-terminal domain
M. Holliday, M. Ultsch, P. Moran, W. Fairbrother +1 more
20210 citations
Semantic Scholar
NMR solution structure of the homodimeric, autoinhibited state of the CARD9 CARD and first coiled-coil
M. Holliday, W. Fairbrother, E. Dueber
20190 citations
Semantic Scholar
The CARD9 CARD domain-swapped dimer with a zinc ion bound to one of the two zinc binding sites
M. Holliday, R. Ferrao, G. Boenig, E. C. Deuber +1 more
20180 citations
Semantic Scholar
NMR solution structure of the CARD9 CARD bound to zinc
M. Holliday, E. Dueber, W. Fairbrother
20180 citations
Semantic Scholar
The CARD9 CARD domain-swapped dimer
M. Holliday, R. Ferrao, G. Boenig, E. C. Deuber +1 more
20180 citations
Semantic Scholar
NMR solution structure of the CARD9 CARD
M. Holliday, E. Dueber, W. Fairbrother
20180 citations
Semantic Scholar
Protein Science: In This Issue
J. Werner, Joshua M. Mitchell, M. Taracila, R. Bonomo +10 more
2017Protein Science0 citations Open access
Semantic Scholar
Allosteric communication networks and enzymatic regulation as mediated by conformational dynamics in the cyclophilin family of peptidyl-prolyl isomerases
M. Holliday
20170 citations
Semantic Scholar
Solution Structure for Cyclophilin A from Geobacillus Kaustophilus
M. Holliday, N. G. Isern, A. Geoffrey, F. Zhang +1 more
20150 citations
Semantic Scholar
Backbone amide assignments for human Cyclophilin C with saturating concentrations of the model peptide GSFGPDLRAGD
M. Holliday, C. Camilloni, G. Armstrong, N. Isern +3 more
20140 citations
Semantic Scholar
Probing the Biophysical Mechanisms of Extracellular Cyclophilin-A in Cancer
M. Holliday, K. Bahmed
20130 citations
Semantic Scholar
Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B
K. Bahmed, Curtis J. Henry, M. Holliday, J. Redzic +6 more
2012Cancer Cell International0 citations Open access
Semantic Scholar

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