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D. Morgens · SciRah

Researcher profile · Semantic Scholar

D. Morgens

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D. Morgens — researcher profile on SciRah

h-index: 25
Works: 69
Citations: 5,195

Most-cited papers

Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2019bioRxiv1,044 citations Open access
Semantic Scholar
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity
M. Burr, C. Sparbier, Yih-Chih Chan, J. Williamson +20 more
2017Nature864 citations Open access
Semantic Scholar
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
K. Han, E. Jeng, G. Hess, D. Morgens +2 more
2017Nature Biotechnology480 citations Open access
Semantic Scholar
CD22 blockade restores homeostatic microglial phagocytosis in aging brains
J. Pluvinage, Michael S. Haney, Benjamin A. H. Smith, Jerry Sun +14 more
2019Nature389 citations Open access
Semantic Scholar
Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens
D. Morgens, Michael Wainberg, E. Boyle, Oana Ursu +11 more
2017Nature Communications357 citations Open access
Semantic Scholar
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9orf72 dipeptide repeat protein toxicity
N. J. Kramer, Michael S. Haney, D. Morgens, A. Jovičić +12 more
2018Nature Genetics196 citations Open access
Semantic Scholar
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, S. Hoogendoorn, A. Kopp, D. Morgens +8 more
2018Nature Genetics177 citations Open access
Semantic Scholar
Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification
Richard M. Deans, D. Morgens, Ayşe Ökesli, S. Pillay +10 more
2016Nature Chemical Biology175 citations Open access
Semantic Scholar
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens
Michael S. Haney, Christopher J. Bohlen, D. Morgens, James Ousey +23 more
2018Nature Genetics166 citations Open access
Semantic Scholar
Mitigation of off-target toxicity in CRISPR-Cas9 screens for essential non-coding elements
Josh Tycko, Michael Wainberg, G. Marinov, Oana Ursu +17 more
2019Nature Communications147 citations Open access
Semantic Scholar
CRISPR-Cas9 screens identify the RNA helicase DDX3X as a repressor of C9ORF72 (GGGGCC)n repeat-associated non-AUG translation
Weiwei Cheng, Shao-Peng Wang, Zhe Zhang, D. Morgens +18 more
2019Neuron126 citations Open access
Semantic Scholar
Genome-wide CRISPR analysis identifies substrate-specific conjugation modules in ER-associated degradation
Dara E. Leto, D. Morgens, Lichao Zhang, C. P. Walczak +3 more
2018Molecules and Cells121 citations Open access
Semantic Scholar
Zmat3 is a key splicing regulator in the p53 tumor suppression program
Kathryn T Bieging-Rolett, A. Kaiser, D. Morgens, A. Boutelle +17 more
2020Molecules and Cells92 citations Open access
Semantic Scholar
CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity
C. K. Tsui, Robyn M. Barfield, Curt R. Fischer, D. Morgens +6 more
2019Nature Chemical Biology77 citations Open access
Semantic Scholar
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
Melissa A. Roberts, Kirandeep K. Deol, Alyssa J. Mathiowetz, M. Lange +12 more
2023Developmental Cell73 citations Open access
Semantic Scholar
Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
Michael M. Dubreuil, D. Morgens, Kanji Okumoto, Masanori Honsho +8 more
2020Cell Reports68 citations Open access
Semantic Scholar
CRISPR–Cas9 screens reveal regulators of ageing in neural stem cells
Tyson Ruetz, Angela N. Pogson, Chloe M. Kashiwagi, Stephanie D. Gagnon +10 more
2024Nature64 citations
Semantic Scholar
Systematic comparison of CRISPR-Cas9 and RNAi screens for essential genes
D. Morgens, Richard M. Deans, Amy Li, M. Bassik
2016Nature Biotechnology60 citations Open access
Semantic Scholar
Targeted genomic CRISPR-Cas9 screen identifies MAP4K4 as essential for glioblastoma invasion
L. Prolo, Amy Li, Scott F. Owen, J. Parker +13 more
2019Scientific Reports51 citations Open access
Semantic Scholar
The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
Masanori Yoshinaga, K. Han, D. Morgens, T. Horii +13 more
2022Nature Communications45 citations Open access
Semantic Scholar
Death-seq identifies regulators of cell death and senolytic therapies
A. Colville, Jie-Yu Liu, Cristina Rodríguez-Mateo, Samantha Thomas +15 more
2022bioRxiv36 citations Open access
Semantic Scholar
Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs
Albert Lu, Paulina S. Wawro, D. Morgens, Fernando Portela +2 more
2018eLife36 citations Open access
Semantic Scholar
High-Throughput Discovery and Characterization of Viral Transcriptional Effectors in Human Cells
Connor H. Ludwig, Abby R. Thurm, D. Morgens, Kevin Yang +4 more
2022bioRxiv31 citations Open access
Semantic Scholar
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2020Nature Neuroscience27 citations Open access
Semantic Scholar
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9orf72 dipeptide repeat protein toxicity
Michael S. Haney, N. J. Kramer, D. Morgens, A. Jovičić +7 more
2017bioRxiv27 citations Open access
Semantic Scholar
Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia
Patricia K. Grüninger, F. Uhl, Heike Herzog, Gaia Gentile +10 more
2022Cancer Gene Therapy25 citations Open access
Semantic Scholar
Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins
D. Morgens, Charlene Chan, Andrew J. Kane, N. Weir +16 more
2019eLife25 citations Open access
Semantic Scholar
Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72
Noori Chai, Michael S. Haney, Julien Couthouis, D. Morgens +7 more
2019bioRxiv22 citations Open access
Semantic Scholar
The Protein Invasion: A Broad Review on the Origin of the Translational System
D. Morgens
2013Journal of Molecular Evolution21 citations
Semantic Scholar
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2020Nature Neuroscience19 citations Open access
Semantic Scholar
An Alternative Look at Code Evolution: Using Non-canonical Codes to Evaluate Adaptive and Historic Models for the Origin of the Genetic Code
D. Morgens, Andre R. O. Cavalcanti
2013Journal of Molecular Evolution17 citations
Semantic Scholar
Protocol for performing pooled CRISPR-Cas9 loss-of-function screens.
Alyssa J. Mathiowetz, Melissa A. Roberts, D. Morgens, James A. Olzmann +1 more
2023STAR Protocols16 citations Open access
Semantic Scholar
CBP modulates sensitivity to dasatinib in pre-BCR+ acute lymphoblastic leukemia
J. Duque-Afonso, Chiou-Hong Lin, K. Han, D. Morgens +14 more
2018Cancer Research14 citations Open access
Semantic Scholar
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Alyssa J. Mathiowetz, Emily S. Meymand, Güneş Parlakgül, Niek van Hilten +22 more
2026Nature12 citations Open access
Semantic Scholar
A Two-tiered functional screen identifies herpesviral transcriptional modifiers and their essential domains
D. Morgens, Divya Nandakumar, A. Didychuk, Ke Yang +1 more
2021bioRxiv12 citations Open access
Semantic Scholar
A genome-wide analysis of targets of macrolide antibiotics in mammalian cells
Amita Gupta, Aye Ökesli-Armlovich, D. Morgens, M. Bassik +1 more
2020Journal of Biological Chemistry12 citations Open access
Semantic Scholar
CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Alyssa J. Mathiowetz, Emily S. Meymand, Kirandeep K. Deol, Güneş Parlakgül +17 more
2024bioRxiv11 citations Open access
Semantic Scholar
Ambushing the ambush hypothesis: predicting and evaluating off-frame codon frequencies in Prokaryotic Genomes
D. Morgens, Charlotte H. Chang, Andre R. O. Cavalcanti
2013BMC Genomics11 citations Open access
Semantic Scholar
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2020Nature Neuroscience10 citations Open access
Semantic Scholar
A Model for the Evolution of Extremely Fragmented Macronuclei in Ciliates
D. Morgens, Kristen M. Lindbergh, Marie Adachi, A. Radunskaya +1 more
2013PLoS ONE10 citations Open access
Semantic Scholar
In vitro and in vivo CRISPR-Cas9 screens reveal drivers of aging in neural stem cells of the brain
Tyson Ruetz, Chloe M. Kashiwagi, Bhek Morton, Robin W. Yeo +6 more
2021bioRxiv9 citations Open access
Semantic Scholar
Novel population genetics in ciliates due to life cycle and nuclear dimorphism.
D. Morgens, Timothy C Stutz, Andre R. O. Cavalcanti
2014Molecular biology and evolution8 citations Open access
Semantic Scholar
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL
Gaia Gentile, T. Poggio, A. Catalano, M. Voutilainen +23 more
2024Blood Advances6 citations Open access
Semantic Scholar
Amitotic chromosome loss predicts distinct patterns of senescence and non-senescence in ciliates.
D. Morgens, Andre R. O. Cavalcanti
2015Protist5 citations
Semantic Scholar
A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for Hedgehog signaling
David K. Breslow, S. Hoogendoorn, A. Kopp, D. Morgens +7 more
2017bioRxiv4 citations Open access
Semantic Scholar
Systematic identification of regulators of antibody-drug conjugate toxicity using CRISPR-Cas9 screens
C. K. Tsui, Robyn M. Barfield, Curt R. Fischer, D. Morgens +5 more
2019bioRxiv3 citations Open access
Semantic Scholar
Enhancers and genome conformation provide complex transcriptional control of a herpesviral gene
D. Morgens, L. Gulyas, Xiaowen Mao, Alejandro Rivera-Madera +2 more
2024Molecular Systems Biology2 citations Open access
Semantic Scholar
From enhancers to genome conformation: complex transcriptional control underlies expression of a single herpesviral gene
D. Morgens, L. Gulyas, Alejandro Rivera-Madera, Annabelle S Souza +1 more
2023bioRxiv2 citations Open access
Semantic Scholar
Parallel CRISPR-Cas9 screens reveal mechanisms of PLIN2 and lipid droplet regulation
Melissa A. Roberts, Kirandeep K. Deol, M. Lange, Dara E. Leto +12 more
2022bioRxiv2 citations Open access
Semantic Scholar
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements
Josh Tycko, Michael Wainberg, G. Marinov, Oana Ursu +17 more
2019bioRxiv2 citations Open access
Semantic Scholar

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