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C. Bertozzi · SciRah

Researcher profile · Semantic Scholar

C. Bertozzi

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C. Bertozzi — researcher profile on SciRah

h-index: 127
Works: 694
Citations: 70K

Most-cited papers

Small RNAs are modified with N-glycans and displayed on the surface of living cells
Ryan A. Flynn, Kayvon Pedram, S. Malaker, Pedro J. Batista +7 more
2021Cell529 citations Open access
Semantic Scholar
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
Green Ahn, Steven M. Banik, Caitlyn L. Miller, N. Riley +2 more
2021Nature Chemical Biology518 citations Open access
Semantic Scholar
The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans
Benjamin A. H. Smith, C. Bertozzi
2021Nature reviews. Drug discovery410 citations Open access
Semantic Scholar
Targeted glycan degradation potentiates the anticancer immune response in vivo
M. Gray, M. Stanczak, N. Mantuano, Han Xiao +9 more
2020Nature Chemical Biology305 citations Open access
Semantic Scholar
Mucus sialylation determines intestinal host-commensal homeostasis
Yikun Yao, Girak Kim, Samantha Shafer, Zuo-Jia Chen +46 more
2022Cell233 citations Open access
Semantic Scholar
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication
Johanna Theruvath, M. Menard, Benjamin A. H. Smith, Miles H. Linde +38 more
2022Nature Medicine218 citations Open access
Semantic Scholar
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
M. Stanczak, N. Mantuano, N. Kirchhammer, David E Sanin +20 more
2021bioRxiv211 citations Open access
Semantic Scholar
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming
Chien-Ting Wu, Peter V. Lidsky, Ying-Hong Xiao, Ran Cheng +18 more
2022Cell191 citations Open access
Semantic Scholar
O-Pair Search with MetaMorpheus for O-glycopeptide Characterization
Lei Lu, N. Riley, Michael R. Shortreed, C. Bertozzi +1 more
2020Nature Methods132 citations Open access
Semantic Scholar
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
Simon Wisnovsky, L. Möckl, S. Malaker, Kayvon Pedram +7 more
2021Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1
Nathaniel W. Mabe, Min Huang, G. N. Dalton, G. Alexe +22 more
2022Nature Cancer125 citations Open access
Semantic Scholar
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
Scott B. Biering, Sylvia A. Sarnik, Eleanor Wang, James R. Zengel +46 more
2022Nature Genetics115 citations Open access
Semantic Scholar
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
G. Forcina, Lauren E. Pope, Magdalena B. Murray, Wentao Dong +3 more
2021bioRxiv92 citations Open access
Semantic Scholar
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
Zheng-Ping Shao, Ryan A. Flynn, J. Crowe, Yimeng Zhu +10 more
2020Nature91 citations Open access
Semantic Scholar
Revealing the human mucinome
S. Malaker, N. Riley, D. J. Shon, Kayvon Pedram +3 more
2021Nature Communications85 citations Open access
Semantic Scholar
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
Kayvon Pedram, D. J. Shon, Gabrielle S. Tender, N. Mantuano +15 more
2022bioRxiv81 citations Open access
Semantic Scholar
Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responses
J. Daly, Subhashis Sarkar, A. Natoni, Jessica C. Stark +4 more
2022Blood Advances80 citations Open access
Semantic Scholar
Organism-wide cell type-specific secretome mapping of exercise training in mice
Wei Wei, N. Riley, Xuchao Lyu, Xiao-Tao Shen +13 more
2023Cell Metabolism79 citations Open access
Semantic Scholar
Degradation from the outside-in: targeting extracellular and membrane proteins for degradation through the endo-lysosomal pathway
Green Ahn, Steven M. Banik, C. Bertozzi
2021Cell Chemical Biology75 citations Open access
Semantic Scholar
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth
E. Scott, Kirsty Hodgson, Beatriz Calle, H. Turner +55 more
2023Oncogene70 citations Open access
Semantic Scholar
MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
Benjamin A. H. Smith, Anja Deutzmann, Kristina Correa, Corleone S. Delaveris +12 more
2023Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
Christopher M. Richards, S. Jabs, Wenjie Qiao, Lauren Varanese +21 more
2022Science66 citations Open access
Semantic Scholar
Butyrate Differentiates Permissiveness to Clostridioides difficile Infection and Influences Growth of Diverse C. difficile Isolates
D. Pensinger, Andrea T. Fisher, Horia A. Dobrila, W. V. Van Treuren +13 more
2022bioRxiv65 citations Open access
Semantic Scholar
Synthetic Siglec-9 Agonists Inhibit Neutrophil Activation Associated with COVID-19
Corleone S. Delaveris, Aaron J. Wilk, N. Riley, Jessica C. Stark +6 more
2020ChemRxiv65 citations Open access
Semantic Scholar
Membrane curvature regulates the spatial distribution of bulky glycoproteins
Chih-Hao Lu, Kayvon Pedram, Ching-Ting Tsai, Taylor Jones +4 more
2022Nature Communications56 citations Open access
Semantic Scholar
Cell-specific bioorthogonal tagging of glycoproteins
A. Cioce, Beatriz Calle, Tatiana Rizou, Sarah C. Lowery +27 more
2022Nature Communications55 citations Open access
Semantic Scholar
Reading the glyco-code: New approaches to studying protein–carbohydrate interactions
Simon Wisnovsky, C. Bertozzi
2022Current Opinion in Structural Biology49 citations Open access
Semantic Scholar
Capture and visualization of live Mycobacterium tuberculosis bacilli from tuberculosis patient bioaerosols
R. Dinkele, S. Gessner, A. McKerry, B. Leonard +15 more
2021PLoS Pathogens46 citations Open access
Semantic Scholar
Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer
Peter A. Szijj, M. Gray, Mikaela K. Ribi, Calise Bahou +3 more
2023Nature Chemistry40 citations Open access
Semantic Scholar
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase
A. Cioce, Ganka Bineva-Todd, A. J. Agbay, Junwon Choi +10 more
2021ACS Chemical Biology37 citations Open access
Semantic Scholar
A Special Virtual Issue Celebrating the 2022 Nobel Prize in Chemistry for the Development of Click Chemistry and Bioorthogonal Chemistry
C. Bertozzi
2022ACS Central Science35 citations Open access
Semantic Scholar
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
J. Pluvinage, Jerry Sun, C. Claes, Ryan A. Flynn +18 more
2021Science Translational Medicine32 citations Open access
Semantic Scholar
Antibody-lectin chimeras for glyco-immune checkpoint blockade
Jessica C. Stark, M. Gray, Itziar Ibarlucea-Benitez, M. Lustig +17 more
2024bioRxiv31 citations Open access
Semantic Scholar
Deacetylated sialic acids modulates immune mediated cytotoxicity via the sialic acid-Siglec pathway.
Susan Grabenstein, Karen N. Barnard, Mathias Tawiah Anim, Albert Armoo +4 more
2021Glycobiology30 citations Open access
Semantic Scholar
Systemic delivery of a targeted synthetic immunostimulant transforms the immune landscape for effective tumor regression
Caitlyn L. Miller, Idit Sagiv-Barfi, P. Neuhöfer, D. Czerwinski +4 more
2021Cell Chemical Biology29 citations Open access
Semantic Scholar
Comprehensive analysis of platelet glycoprotein Ibα ectodomain glycosylation
Marie A. Hollenhorst, Katherine H. Tiemeyer, Keira E. Mahoney, K. Aoki +5 more
2023Journal of Thrombosis and Haemostasis28 citations Open access
Semantic Scholar
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2020Nature Neuroscience27 citations Open access
Semantic Scholar
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
D. J. Shon, D. Fernandez, N. Riley, Michael J. Ferracane +1 more
2022Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection
Scott B. Biering, Sylvia A. Sarnik, Eleanor Wang, James R. Zengel +16 more
2021bioRxiv25 citations Open access
Semantic Scholar
Microglia Mediate Contact-Independent Neuronal Network Remodeling via Secreted Neuraminidase-3 Associated with Extracellular Vesicles
Corleone S. Delaveris, Catherine L. Wang, N. Riley, Sherry Li +2 more
2023ACS Central Science22 citations
Semantic Scholar
Deciphering O-glycoprotease substrate preferences with O-Pair Search†
N. Riley, C. Bertozzi
2022Molecular Omics22 citations Open access
Semantic Scholar
Author Correction: Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Julia Marschallinger, T. Iram, Macy E. Zardeneta, S. Lee +14 more
2020Nature Neuroscience19 citations Open access
Semantic Scholar
Analyzing nested experimental designs—A user-friendly resampling method to determine experimental significance
Rishikesh U. Kulkarni, Catherine L. Wang, C. Bertozzi
2021bioRxiv18 citations Open access
Semantic Scholar
Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection
Ryan A. Flynn, Julia A. Belk, Yan-Yan Qi, Yuki Yasumoto +12 more
2020bioRxiv18 citations Open access
Semantic Scholar
Bioluminogenic Probe for Rapid, Ultrasensitive Detection of β-Lactam-Resistant Bacteria
Tingting Dai, Jinghang Xie, Joseph A Buonomo, Angel Moreno +3 more
2023Analytical Chemistry17 citations Open access
Semantic Scholar
Differentially culturable tubercle bacteria as a measure of tuberculosis treatment response
Julian S. Peters, Amanda McIvor, A. O. Papadopoulos, Tshepiso Masangana +9 more
2023Frontiers in Cellular and Infection Microbiology17 citations Open access
Semantic Scholar
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE
Joann Chongsaritsinsuk, Alexandra D. Steigmeyer, Keira E. Mahoney, Mia A. Rosenfeld +13 more
2023bioRxiv16 citations Open access
Semantic Scholar
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
Kayvon Pedram, N. Laqtom, D. J. Shon, A. Di Spiezio +4 more
2022Proceedings of the National Academy of Sciences of the United States of America15 citations Open access
Semantic Scholar
Multi-omics analysis of spatially distinct stromal cells reveals tumor-induced O-glycosylation of the CDK4-pRB axis in fibroblasts at the invasive tumor edge
G. Bouchard, Fernando Jose Garcia Marques, L. Karacosta, Weiruo Zhang +10 more
2021Cancer Research14 citations Open access
Semantic Scholar
Serial measurement of M. tuberculosis in blood from critically-ill patients with HIV-associated tuberculosis
D. Barr, C. Schutz, Avuyonke Balfour, M. Shey +14 more
2022EBioMedicine13 citations Open access
Semantic Scholar

Frequent co-authors

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N. Riley×17
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N. Riley — researcher profile on SciRah
S. Malaker×9
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S. Malaker — researcher profile on SciRah
D. J. Shon×7
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D. J. Shon — researcher profile on SciRah
Kayvon Pedram×6
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Kayvon Pedram — researcher profile on SciRah

Benjamin A. H. Smith

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M. Gray — researcher profile on SciRah

Simon Wisnovsky×6

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Simon Wisnovsky — researcher profile on SciRah

Jessica C. Stark×6

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Jessica C. Stark — researcher profile on SciRah

Ryan A. Flynn×5

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Ryan A. Flynn — researcher profile on SciRah

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J. Carette — researcher profile on SciRah

Caitlyn L. Miller×4

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Caitlyn L. Miller — researcher profile on SciRah

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B. Schumann — researcher profile on SciRah