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James A. Olzmann · SciRah

Researcher profile · Semantic Scholar

James A. Olzmann

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James A. Olzmann — researcher profile on SciRah

h-index: 45
Works: 113
Citations: 21K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
The CoQ oxidoreductase FSP1 acts in parallel to GPX4 to inhibit ferroptosis
K. Bersuker, Joseph M. Hendricks, Zhipeng Li, Leslie Magtanong +10 more
2019Nature3,387 citations Open access
Semantic Scholar
Dynamics and functions of lipid droplets
James A. Olzmann, Pedro Carvalho
2018Nature reviews. Molecular cell biology2,390 citations Open access
Semantic Scholar
The cell biology of ferroptosis
S. Dixon, James A. Olzmann
2024Nature reviews. Molecular cell biology1,532 citations
Semantic Scholar
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State
Leslie Magtanong, Pin-Joe Ko, Milton To, J. Cao +8 more
2019Cell Chemical Biology1,071 citations Open access
Semantic Scholar
DGAT1-dependent lipid droplet biogenesis protects mitochondrial function during starvation-induced autophagy
Truc B Nguyen, Sharon M. Louie, J. Daniele, Quan Tran +4 more
2017Developmental Cell564 citations Open access
Semantic Scholar
Defining human ERAD networks through an integrative mapping strategy
J. C. Christianson, James A. Olzmann, T. Shaler, M. Sowa +6 more
2011Nature Cell Biology500 citations Open access
Semantic Scholar
Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation
Jessica N. Spradlin, Xirui Hu, Carl C. Ward, S. Brittain +14 more
2018bioRxiv359 citations Open access
Semantic Scholar
A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes
K. Bersuker, C. Peterson, Milton To, S. Sahl +4 more
2017Developmental Cell345 citations Open access
Semantic Scholar
The Mammalian Endoplasmic Reticulum-Associated Degradation System
James A. Olzmann, R. Kopito, J. C. Christianson
2013Cold Spring Harbor Perspectives in Biology336 citations Open access
Semantic Scholar
Ferroptosis in health and disease
C. Berndt, Hamed Alborzinia, Vera Skafar Amen, S. Ayton +90 more
2024Redox Biology288 citations Open access
Semantic Scholar
A Genome-wide ER-Phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
Jin-Rui Liang, Emily Lingeman, Thao Luong, Saba Ahmed +4 more
2020Cell283 citations Open access
Semantic Scholar
Lipid droplets and cellular lipid flux
Alyssa J. Mathiowetz, James A. Olzmann
2024Nature Cell Biology268 citations
Semantic Scholar
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
James A. Olzmann, C. Richter, R. Kopito
2013Proceedings of the National Academy of Sciences of the United States of America233 citations Open access
Semantic Scholar
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum
Ethan J. Greenblatt, James A. Olzmann, R. Kopito
2011Nature Structural &Molecular Biology197 citations Open access
Semantic Scholar
Covalent Targeting of the Vacuolar H+-ATPase Activates Autophagy Via mTORC1 Inhibition
C. Chung, Hijai R. Shin, Charles A. Berdan, Breanna Ford +4 more
2019Nature Chemical Biology172 citations Open access
Semantic Scholar
Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation
K. Bersuker, James A. Olzmann
2017Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids147 citations Open access
Semantic Scholar
Endoplasmic Reticulum–Associated Degradation and Lipid Homeostasis
J. Stevenson, Edmond Y. Huang, James A. Olzmann
2016Annual review of nutrition145 citations Open access
Semantic Scholar
Parkin-mediated ubiquitin signalling in aggresome formation and autophagy
L. Chin, James A. Olzmann, Lian Li
2010Biochemical Society Transactions138 citations Open access
Semantic Scholar
Context-Dependent Regulation of Ferroptosis Sensitivity
Leslie Magtanong, Grace D. Mueller, K. Williams, Maximillian Billmann +8 more
2022Cell Chemical Biology120 citations Open access
Semantic Scholar
Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability
Zhipeng Li, Lucas Ferguson, Kirandeep K. Deol, Melissa A. Roberts +11 more
2022Nature Chemical Biology115 citations Open access
Semantic Scholar
Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
Joseph M. Hendricks, Cody E Doubravsky, Eddie Wehri, Zhipeng Li +9 more
2022bioRxiv113 citations Open access
Semantic Scholar
Sensitization of Cancer Cells to Ferroptosis Coincident with Cell Cycle Arrest
Jason J. Rodencal, Nathan Kim, Andy L. He, Veronica L. Li +8 more
2023Cell Chemical Biology106 citations Open access
Semantic Scholar
Protein Quality Control and Lipid Droplet Metabolism
Melissa A. Roberts, James A. Olzmann
2020Annual Review of Cell and Developmental Biology98 citations Open access
Semantic Scholar
Lipid droplets and lipotoxicity during autophagy
Truc B Nguyen, James A. Olzmann
2017Autophagy98 citations Open access
Semantic Scholar
Unassembled CD147 is an endogenous endoplasmic reticulum–associated degradation substrate
R. E. Tyler, Margaret M. P. Pearce, T. Shaler, James A. Olzmann +2 more
2012Molecular Biology of the Cell88 citations Open access
Semantic Scholar
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells
Charles A. Berdan, R. Ho, H. Lehtola, Milton To +8 more
2019bioRxiv84 citations Open access
Semantic Scholar
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
Melissa A. Roberts, Kirandeep K. Deol, Alyssa J. Mathiowetz, M. Lange +12 more
2023Developmental Cell73 citations Open access
Semantic Scholar
Mutations associated with Charcot–Marie–Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome–autophagy pathways
Samuel M. Lee, James A. Olzmann, L. Chin, Lian Li
2011Journal of Cell Science73 citations Open access
Semantic Scholar
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology
N. Mejhert, Katlyn R. Gabriel, Scott Frendo-Cumbo, Natalie Krahmer +13 more
2021bioRxiv66 citations Open access
Semantic Scholar
Corneal Dystrophy-associated R124H Mutation Disrupts TGFBI Interaction with Periostin and Causes Mislocalization to the Lysosome*
Bong-yoon Kim, James A. Olzmann, Seung-Il Choi, S. Ahn +4 more
2009Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Lipid Quality Control and Ferroptosis: From Concept to Mechanism
Zhipeng Li, Mike Lange, S. Dixon, James A. Olzmann
2023Annual Review of Biochemistry63 citations Open access
Semantic Scholar
Chemoproteomics-Enabled Covalent Ligand Screen Reveals a Cysteine Hotspot in Reticulon 4 that Impairs ER Morphology and Cancer Pathogenicity
L. Bateman, Truc B Nguyen, Allison M. Roberts, David K. Miyamoto +8 more
2017Chemical Communications62 citations Open access
Semantic Scholar
Selenium reduction of ubiquinone via SQOR suppresses ferroptosis
Namgyu Lee, Sung Jin Park, M. Lange, T. Tseyang +8 more
2023bioRxiv61 citations Open access
Semantic Scholar
Lipid Droplet Formation Is Dispensable for Endoplasmic Reticulum-associated Degradation*
James A. Olzmann, R. Kopito
2011Journal of Biological Chemistry55 citations Open access
Semantic Scholar
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis
Mike Lange, Michele Wölk, V. Li, Cody E Doubravsky +12 more
2025Nature Cell Biology46 citations Open access
Semantic Scholar
Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1
Jiwon Hwang, C. P. Walczak, T. Shaler, James A. Olzmann +3 more
2017Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Diversity through equity and inclusion: The responsibility belongs to all of us
James A. Olzmann
2020Molecular Biology of the Cell34 citations Open access
Semantic Scholar
Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation
Milton To, C. Peterson, Melissa A. Roberts, Jessica L. Counihan +4 more
2017Molecular Biology of the Cell33 citations Open access
Semantic Scholar
SPFH1 and SPFH2 Mediate the Ubiquitination and Degradation of Inositol 1,4,5-Trisphosphate Receptors in Muscarinic Receptor-Expressing Hela Cells
Y. Wang, Margaret M. P. Pearce, D. Sliter, James A. Olzmann +7 more
2009Biochimica et Biophysica Acta33 citations Open access
Semantic Scholar
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates
Edmond Y. Huang, Milton To, Erica Tran, Lorraine T. Ador Dionisio +4 more
2018Molecular Biology of the Cell31 citations Open access
Semantic Scholar
Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity
K. Anderson, Milton To, James A. Olzmann, D. Nomura
2017ACS Chemical Biology31 citations Open access
Semantic Scholar
VPS13A and VPS13C Influence Lipid Droplet Abundance
Shu-Liang Chen, Melissa A. Roberts, Chun-Yuan Chen, Sebastian J. Markmiller +5 more
2022bioRxiv26 citations Open access
Semantic Scholar
FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis
Mike Lange, Michele Wölk, Cody E Doubravsky, Joseph M. Hendricks +6 more
2025bioRxiv25 citations Open access
Semantic Scholar
Hijacking Extracellular Targeted Protein Degrader–Drug Conjugates for Enhanced Drug Delivery
Fang-Zhu Zhao, Yan Wu, K. Schaefer, Yun Zhang +9 more
2025Journal of the American Chemical Society24 citations
Semantic Scholar
Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD
Ethan J. Greenblatt, James A. Olzmann, R. Kopito
2012Nature Structural &Molecular Biology24 citations Open access
Semantic Scholar
Ending on a sour note: Lipids orchestrate ferroptosis in cancer.
M. Lange, James A. Olzmann
2021Cell Metabolism23 citations Open access
Semantic Scholar
Cocrystal structure reveals the mechanism of FSP1 inhibition by FSEN1
Sitao Zhang, Amalia H. Megarioti, Joseph M. Hendricks, Junshuo Zhou +3 more
2025Proceedings of the National Academy of Sciences of the United States of America17 citations
Semantic Scholar
Optimized protocol for the identification of lipid droplet proteomes using proximity labeling proteomics in cultured human cells
C. Peterson, Kirandeep K. Deol, Milton To, James A. Olzmann
2021STAR Protocols17 citations Open access
Semantic Scholar
DCAF16-Based Covalent Degradative Handles for the Modular Design of Degraders
Lauren M Orr, Sydney J. Tomlinson, Hannah R. Grupe, Melissa Lim +6 more
2025bioRxiv16 citations Open access
Semantic Scholar

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