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M. Ahmadian · SciRah

Researcher profile · Semantic Scholar

M. Ahmadian

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M. Ahmadian — researcher profile on SciRah

h-index: 59
Works: 187
Citations: 12K

Most-cited papers

The RHO Family GTPases: Mechanisms of Regulation and Signaling
Niloufar Mosaddeghzadeh, M. Ahmadian
2021Cells328 citations Open access
Semantic Scholar
The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling
Paul Baran, S. Hansen, G. H. Waetzig, M. Akbarzadeh +5 more
2018Journal of Biological Chemistry206 citations Open access
Semantic Scholar
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network
A. Caye, M. Strullu, F. Guidez, B. Cassinat +29 more
2015Nature Genetics185 citations
Semantic Scholar
Illuminating the functional and structural repertoire of human TBC/RABGAPs
M. Frasa, Katja T. Koessmeier, M. Ahmadian, Vania M. M. Braga
2012Nature reviews. Molecular cell biology180 citations
Semantic Scholar
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function
Michael T. Lam, Simona Coppola, Oliver H. F. Krumbach, G. Prencipe +56 more
2019Journal of Experimental Medicine176 citations Open access
Semantic Scholar
Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes.
S. Martinelli, Oliver H. F. Krumbach, F. Pantaleoni, Simona Coppola +44 more
2018American Journal of Human Genetics170 citations Open access
Semantic Scholar
Rho-kinase: regulation, (dys)function, and inhibition
Ehsan Amin, B. Dubey, Si-Cai Zhang, L. Gremer +7 more
2013Biological chemistry162 citations Open access
Semantic Scholar
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis
E. Flex, M. Jaiswal, F. Pantaleoni, S. Martinelli +44 more
2014Human Molecular Genetics136 citations Open access
Semantic Scholar
Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases
R. Linka, Sarah L. Risse, K. Bienemann, M. Werner +21 more
2012Leukemia131 citations
Semantic Scholar
Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice.
M. Kraft, Ion C. Cirstea, A. Voss, T. Thomas +14 more
2011Journal of Clinical Investigation111 citations Open access
Semantic Scholar
Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins
Ehsan Amin, M. Jaiswal, U. Derewenda, K. Reis +6 more
2016Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Deciphering the Molecular and Functional Basis of Dbl Family Proteins
M. Jaiswal, R. Dvorský, M. Ahmadian
2012Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation.
M. Frasa, Filipe C. Maximiano, Kasia Smolarczyk, Richard E. Francis +7 more
2010Current Biology103 citations Open access
Semantic Scholar
The Microenvironment of the Pathogenesis of Cardiac Hypertrophy
Farhad Bazgir, Julia Nau, S. Nakhaei-Rad, Ehsan Amin +4 more
2023Cells93 citations Open access
Semantic Scholar
Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)*
M. Jaiswal, L. Gremer, R. Dvorský, L. Haeusler +3 more
2011Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Critical off‐target effects of the widely used Rac1 inhibitors NSC23766 and EHT1864 in mouse platelets
Sebastian Dütting, J. Heidenreich, Deya Cherpokova, E. Amin +4 more
2015Journal of Thrombosis and Haemostasis73 citations Open access
Semantic Scholar
The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions
H. Nakhaeizadeh, Ehsan Amin, S. Nakhaei-Rad, R. Dvorský +1 more
2016PLoS ONE70 citations Open access
Semantic Scholar
Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome.
Y. Capri, E. Flex, Oliver H. F. Krumbach, Giovanna Carpentieri +29 more
2019American Journal of Human Genetics68 citations Open access
Semantic Scholar
Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering
O. Blaževitš, Yonatan G. Mideksa, Maja Šolman, Alessio Ligabue +7 more
2016Scientific Reports66 citations Open access
Semantic Scholar
Specific mosaic KRAS mutations affecting codon 146 cause oculoectodermal syndrome and encephalocraniocutaneous lipomatosis
Sangamitra Boppudi, N. Bögershausen, Hanne B Hove, E. Perçin +15 more
2016Clinical Genetics64 citations
Semantic Scholar
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line
Silke Pudewell, Christoph Wittich, Neda S. Kazemein Jasemi, Farhad Bazgir +1 more
2021Communications Biology61 citations Open access
Semantic Scholar
Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin
M. S. Taha, K. Nouri, L. Milroy, Jens M. Moll +4 more
2014PLoS ONE61 citations Open access
Semantic Scholar
bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling
F. Haghighi, J. Dahlmann, S. Nakhaei-Rad, A. Lang +5 more
2018Cell Communication and Signaling54 citations Open access
Semantic Scholar
Rigosertib potently protects against colitis-associated intestinal fibrosis and inflammation by regulating PI3K/AKT and NF-κB signaling pathways.
F. Rahmani, F. Asgharzadeh, A. Avan, F. Barneh +8 more
2020Life Science47 citations Open access
Semantic Scholar
New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm
M. Jaiswal, E. Fansa, R. Dvorský, M. Ahmadian
2013Biological chemistry47 citations
Semantic Scholar
Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission
Simone Mayer, Rohit Kumar, M. Jaiswal, Tolga Soykan +5 more
2013Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Novel FMRP interaction networks linked to cellular stress
M. S. Taha, F. Haghighi, A. Stefanski, S. Nakhaei-Rad +9 more
2020The FEBS Journal46 citations
Semantic Scholar
Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy.
M. Motta, L. Sagi-Dain, Oliver H. F. Krumbach, A. Hahn +16 more
2020Human Molecular Genetics45 citations
Semantic Scholar
Optimization of Laminated Composites by Using Genetic Algorithm and the Polar Description of Plane Anisotropy
A. Vincenti, P. Vannucci, M. Ahmadian
201345 citations Open access
Semantic Scholar
Genotype and phenotype spectrum of NRAS germline variants
Franziska Altmüller, Christina Lissewski, D. Bertola, E. Flex +22 more
2017European Journal of Human Genetics44 citations Open access
Semantic Scholar
Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.
Ion C. Cirstea, L. Gremer, R. Dvorský, Si-Cai Zhang +3 more
2013Human Molecular Genetics44 citations
Semantic Scholar
The Centrosomal Adaptor TACC3 and the Microtubule Polymerase chTOG Interact via Defined C-terminal Subdomains in an Aurora-A Kinase-independent Manner*
H. C. Thakur, Madhurendra Singh, Luitgard Nagel-Steger, J. Kremer +10 more
2013Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoforms
S. Nakhaei-Rad, F. Haghighi, Parivash Nouri, Soheila Rezaei Adariani +4 more
2018Critical reviews in biochemistry and molecular biology40 citations
Semantic Scholar
Functional Cross-talk between Ras and Rho Pathways
M. Jaiswal, R. Dvorský, Ehsan Amin, Sarah L. Risse +11 more
2014Journal of Biological Chemistry39 citations Open access
Semantic Scholar
A Systematic Compilation of Human SH3 Domains: A Versatile Superfamily in Cellular Signaling
Mehrnaz Mehrabipour, Neda S. Kazemein Jasemi, R. Dvorský, M. Ahmadian
2023Cells37 citations Open access
Semantic Scholar
Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division
H. C. Thakur, Madhurendra Singh, Luitgard Nagel-Steger, Daniel Prumbaum +8 more
2013Biological chemistry34 citations Open access
Semantic Scholar
The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells*
S. Nakhaei-Rad, H. Nakhaeizadeh, S. Götze, C. Kordes +8 more
2016Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Selective inhibition of IL-6 trans-signaling by a miniaturized, optimized chimeric soluble gp130 inhibits TH17 cell expansion
Denise Heise, Alicia Derrac Soria, S. Hansen, Christine Dambietz +8 more
2021Science Signaling31 citations
Semantic Scholar
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues
S. Nakhaei-Rad, F. Haghighi, Farhad Bazgir, J. Dahlmann +26 more
2023Communications Biology30 citations Open access
Semantic Scholar
Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury
P. Bouvain, Z. Ding, Shiwa Kadir, Patricia Kleimann +25 more
2023Nature Cardiovascular Research30 citations Open access
Semantic Scholar
Optimizing the synthesis and purification of MS2 virus like particles
K. Hashemi, M. M. Ghahramani Seno, M. Ahmadian, Bizhan Malaekeh-Nikouei +3 more
2021Scientific Reports30 citations Open access
Semantic Scholar
Structural snapshots of RAF kinase interactions.
Soheila Rezaei Adariani, Marcel Buchholzer, M. Akbarzadeh, S. Nakhaei-Rad +2 more
2018Biochemical Society Transactions30 citations
Semantic Scholar
Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiation
Verena Ziegler, C. Henninger, I. Simiantonakis, Marcel Buchholzer +3 more
2017Cell Death and Disease29 citations Open access
Semantic Scholar
Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11
K. Nouri, Jens M. Moll, L. Milroy, Anika Hain +11 more
2015PLoS ONE29 citations Open access
Semantic Scholar
Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy
Franziska Altmüller, Santosh Pothula, Anil Annamneedi, S. Nakhaei-Rad +10 more
2017PLoS Genetics27 citations Open access
Semantic Scholar
The anticancer phytochemical rocaglamide inhibits Rho GTPase activity and cancer cell migration
Michael S. Becker, Paul M. Müller, J. Bajorat, Anne E. Schroeder +7 more
2016OncoTarget26 citations Open access
Semantic Scholar
Biochemical assays to characterize Rho GTPases.
M. Jaiswal, B. Dubey, Katja T. Koessmeier, L. Gremer +1 more
2012Methods in molecular biology26 citations
Semantic Scholar
New model for the interaction of IQGAP1 with CDC42 and RAC1
K. Nouri, D. Timson, M. Ahmadian
2020Small GTPases25 citations Open access
Semantic Scholar
Physical characterization and uptake of iron oxide nanoparticles of different prostate cancer cells
Maryam Youhannayee, S. Nakhaei-Rad, F. Haghighi, Karsten Klauke +5 more
2019Journal of Magnetism and Magnetic Materials25 citations
Semantic Scholar
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands.
Neda S. Kazemein Jasemi, C. Herrmann, E. Estirado, L. Gremer +4 more
2021Biochemical Journal24 citations Open access
Semantic Scholar

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