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R. Gherzi · SciRah

Researcher profile · Semantic Scholar

R. Gherzi

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R. Gherzi — researcher profile on SciRah

h-index: 34
Works: 92
Citations: 5,880

Most-cited papers

AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.
Ching-Yi Chen, R. Gherzi, Shao-En Ong, E. L. Chan +6 more
2001Cell933 citations Open access
Semantic Scholar
A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery.
R. Gherzi, Kyung-Yeol Lee, P. Briata, Daniel Wegmüller +3 more
2004Molecules and Cells488 citations Open access
Semantic Scholar
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.
C.-K. Chou, Thomas J. Dull, D. S. Russell, R. Gherzi +3 more
1987Journal of Biological Chemistry474 citations Open access
Semantic Scholar
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation.
Ching-Yi Chen, R. Gherzi, J. Andersen, G. Gaietta +4 more
2000Genes & Development416 citations Open access
Semantic Scholar
The RNA-binding Protein KSRP Promotes the Biogenesis of a Subset of miRNAs
M. Trabucchi, P. Briata, M. García-Mayoral, A. Haase +4 more
2009Nature328 citations Open access
Semantic Scholar
p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.
P. Briata, S. Forcales, M. Ponassi, G. Corte +4 more
2005Molecules and Cells248 citations Open access
Semantic Scholar
LPS induces KH‐type splicing regulatory protein‐dependent processing of microRNA‐155 precursors in macrophages
Tina Ruggiero, M. Trabucchi, F. De Santa, S. Zupo +5 more
2009The FASEB Journal224 citations
Semantic Scholar
The Wnt/beta-catenin-->Pitx2 pathway controls the turnover of Pitx2 and other unstable mRNAs.
P. Briata, Cristina Ilengo, G. Corte, C. Moroni +3 more
2003Molecules and Cells174 citations Open access
Semantic Scholar
The ARE‐dependent mRNA‐destabilizing activity of BRF1 is regulated by protein kinase B
M. Schmidlin, Min-Ren Lu, S. Leuenberger, G. Stoecklin +6 more
2004EMBO Journal154 citations Open access
Semantic Scholar
KH domains with impaired nucleic acid binding as a tool for functional analysis
D. Hollingworth, A. M. Candel, G. Nicastro, Stephen R. Martin +3 more
2012Nucleic Acids Research136 citations Open access
Semantic Scholar
Tethering KSRP, a Decay-Promoting AU-Rich Element-Binding Protein, to mRNAs Elicits mRNA Decay
C. Chou, Alok Mulky, Sushmit Maitra, Wei-Jye Lin +3 more
2006Molecular and Cellular Biology125 citations
Semantic Scholar
The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation.
M. García-Mayoral, D. Hollingworth, L. Masino, I. Díaz-Moreno +5 more
2007Structure121 citations Open access
Semantic Scholar
H19 long noncoding RNA controls the mRNA decay promoting function of KSRP
M. Giovarelli, Gabriele Bucci, A. Ramos, D. Bordo +5 more
2014Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation.
D. S. Russell, R. Gherzi, E. L. Johnson, C.-K. Chou +1 more
1987Journal of Biological Chemistry116 citations Open access
Semantic Scholar
PHOSPHORYLATION-MEDIATED UNFOLDING OF A KH DOMAIN REGULATES KSRP LOCALISATION VIA 14-3-3 BINDING
I. Díaz-Moreno, D. Hollingworth, T. Frenkiel, G. Kelly +6 more
2009Nature Structural &Molecular Biology101 citations Open access
Semantic Scholar
The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling
R. Gherzi, M. Trabucchi, M. Ponassi, Tina Ruggiero +6 more
2006PLoS Biology95 citations Open access
Semantic Scholar
Posttranscriptional Control of Type I Interferon Genes by KSRP in the Innate Immune Response against Viral Infection
Wei Lin, Xiaojia Zheng, Chen-Chung Lin, J. Tsao +8 more
2011Molecular and Cellular Biology88 citations Open access
Semantic Scholar
Diverse roles of the nucleic acid binding protein KHSRP in cell differentiation and disease
P. Briata, D. Bordo, Margherita Puppo, Franco Gorlero +3 more
2015Wiley Interdisciplinary Reviews - RNA85 citations Open access
Semantic Scholar
PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis
P. Briata, W.-J. Lin, M. Giovarelli, M. Pasero +5 more
2011Cell Death and Differentiation84 citations Open access
Semantic Scholar
Functional and molecular insights into KSRP function in mRNA decay.
P. Briata, Ching-Yi Chen, A. Ramos, R. Gherzi
2013Biochimica et Biophysica Acta75 citations
Semantic Scholar
LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β
M. Rossi, Gabriele Bucci, D. Rizzotto, D. Bordo +11 more
2019Nature Communications74 citations Open access
Semantic Scholar
The role of KSRP in mRNA decay and microRNA precursor maturation
R. Gherzi, Ching-Yi Chen, M. Trabucchi, A. Ramos +1 more
2010Wiley Interdisciplinary Reviews - RNA72 citations
Semantic Scholar
miRNA-Mediated KHSRP Silencing Rewires Distinct Post-transcriptional Programs during TGF-β-Induced Epithelial-to-Mesenchymal Transition.
Margherita Puppo, Gabriele Bucci, M. Rossi, M. Giovarelli +5 more
2016Cell Reports63 citations Open access
Semantic Scholar
Destabilization of Nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fiber formation
A. Cammas, B. J. Sánchez, Xian J. Lian, V. Dormoy-Raclet +11 more
2014Nature Communications63 citations Open access
Semantic Scholar
The mRNA decay promoting factor K‐homology splicing regulator protein post‐transcriptionally determines parathyroid hormone mRNA levels
Morris Nechama, I. Ben-Dov, P. Briata, R. Gherzi +1 more
2008The FASEB Journal61 citations
Semantic Scholar
KSRP, many functions for a single protein.
P. Briata, Ching-Yi Chen, M. Giovarelli, M. Pasero +3 more
2011Frontiers in Bioscience56 citations Open access
Semantic Scholar
KSRP and MicroRNA 145 Are Negative Regulators of Lipolysis in White Adipose Tissue
Yi-Yu Lin, C. Chou, M. Giovarelli, P. Briata +2 more
2014Molecular and Cellular Biology54 citations Open access
Semantic Scholar
KSRP Ablation Enhances Brown Fat Gene Program in White Adipose Tissue Through Reduced miR-150 Expression
C. Chou, Yi-Yu Lin, Hsu-Kun Wang, Xiaolin Zhu +5 more
2014Diabetes53 citations Open access
Semantic Scholar
AP-1 activity during normal human keratinocyte differentiation: evidence for a cytosolic modulator of AP-1/DNA binding.
P. Briata, F. D'Anna, A. Franzi, R. Gherzi
1993Experimental Cell Research51 citations
Semantic Scholar
KSRP controls pleiotropic cellular functions.
R. Gherzi, Ching-Yi Chen, A. Ramos, P. Briata
2014Seminars in Cell and Developmental Biology48 citations
Semantic Scholar
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.
R. Gherzi, D. S. Russell, Simeon I. Taylor, O. Rosen
1987Journal of Biological Chemistry44 citations Open access
Semantic Scholar
“HepG2/erythroid/brain” type glucose transporter (GLUT1) is highly expressed in human epidermis: Keratinocyte differentiation affects glut1 levels in reconstituted epidermis
R. Gherzi, G. Melioli, M. De Luca, A. d'Agostino +5 more
1992Journal of Cellular Physiology42 citations Open access
Semantic Scholar
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets
I. Díaz-Moreno, D. Hollingworth, G. Kelly, Stephen R. Martin +4 more
2010Nucleic Acids Research41 citations Open access
Semantic Scholar
Long Non-Coding RNA-Ribonucleoprotein Networks in the Post-Transcriptional Control of Gene Expression
P. Briata, R. Gherzi
2020Non-Coding RNA40 citations Open access
Semantic Scholar
How to control miRNA maturation? Co-activators and co-repressors take the stage
M. Trabucchi, P. Briata, W. Filipowicz, M. Rosenfeld +2 more
200934 citations Open access
Semantic Scholar
Non-canonical Guanine recognition mediates KSRP regulation of Let-7 biogenesis
G. Nicastro, M. García-Mayoral, D. Hollingworth, G. Kelly +4 more
2012Nature Structural &Molecular Biology33 citations Open access
Semantic Scholar
How to control miRNA maturation?
M. Trabucchi, P. Briata, W. Filipowicz, M. Rosenfeld +2 more
2009RNA Biology33 citations
Semantic Scholar
KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells
Morris Nechama, Yong Peng, O. Bell, P. Briata +3 more
2009BMC Cell Biology31 citations Open access
Semantic Scholar
High expression levels of the "erythroid/brain" type glucose transporter (GLUT1) in the basal cells of human eye conjunctiva and oral mucosa reconstituted in culture.
R. Gherzi, G. Melioli, M. De Luca, A. d'Agostino +5 more
1991Experimental Cell Research31 citations Open access
Semantic Scholar
Let-7b/c Enhance the Stability of a Tissue-Specific mRNA during Mammalian Organogenesis as Part of a Feedback Loop Involving KSRP
Emanuela Repetto, P. Briata, Nathalie Kuziner, B. Harfe +4 more
2012PLoS Genetics29 citations Open access
Semantic Scholar
Glucose starvation and glycosylation inhibitors reduce insulin receptor gene expression: characterization and potential mechanism in human cells.
P. Briata, L. Briata, R. Gherzi
1990Biochemical and Biophysical Research Communications - BBRC28 citations
Semantic Scholar
Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.
M. Pasero, M. Giovarelli, Gabriele Bucci, R. Gherzi +1 more
2012Cell Reports27 citations Open access
Semantic Scholar
KSRP Promotes the Maturation of a Group of miRNA Precuresors.
M. Trabucchi, P. Briata, W. Filipowicz, A. Ramos +2 more
2011Advances in Experimental Medicine and Biology27 citations
Semantic Scholar
Androgens increase insulin receptor mRNA levels, insulin binding, and insulin responsiveness in HEp-2 larynx carcinoma cells.
G. Sesti, M. Marini, P. Briata, A. N. Tullio +5 more
1992Molecular and Cellular Endocrinology22 citations
Semantic Scholar
Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.
Arfa Moshiri, Margherita Puppo, M. Rossi, R. Gherzi +1 more
2017Biochimica et Biophysica Acta. Gene Regulatory Mechanisms19 citations
Semantic Scholar
c-myc gene expression in human cells is controlled by glucose.
P. Briata, Cinzia Laurino, R. Gherzi
1989Biochemical and Biophysical Research Communications - BBRC19 citations
Semantic Scholar
Comprehensive multi-omics analysis uncovers a group of TGF-β-regulated genes among lncRNA EPR direct transcriptional targets
Ettore Zapparoli, P. Briata, M. Rossi, Lorenzo Brondolo +2 more
2020Nucleic Acids Research18 citations Open access
Semantic Scholar
Bcl-2 Protein Is Required for the Adenine/Uridine-rich Element (ARE)-dependent Degradation of Its Own Messenger*
Annamaria Bevilacqua, Maria Cristina Ceriani, G. Canti, L. Asnaghi +6 more
2003Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Assignment of the tenascin-R gene (Tnr) to mouse chromosome 4 band E2 by fluorescence in situ hybridization; refinement of the human TNR location to chromosome 1q24.
Giulia Arrigo, R. Gherzi, M. Bonaglia, A. Leprini +2 more
1997Cytogenetics and Cell Genetics17 citations
Semantic Scholar
Rat tenascin-R gene: structure, chromosome location and transcriptional activity of promoter and exon 1
A. Leprini, R. Gherzi, E. Vecchi, L. Borsi +2 more
1999Cytogenetic and Genome Research14 citations
Semantic Scholar

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