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D. Hollingworth · SciRah

Researcher profile · Semantic Scholar

D. Hollingworth

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D. Hollingworth — researcher profile on SciRah

h-index: 19
Works: 47
Citations: 1,335

Most-cited papers

KH domains with impaired nucleic acid binding as a tool for functional analysis
D. Hollingworth, A. M. Candel, G. Nicastro, Stephen R. Martin +3 more
2012Nucleic Acids Research136 citations Open access
Semantic Scholar
G-quartet-dependent recognition between the FMRP RGG box and RNA.
A. Ramos, D. Hollingworth, A. Pastore
2003RNA: A publication of the RNA Society126 citations Open access
Semantic Scholar
Key features of the interaction between Pcf11 CID and RNA polymerase II CTD
C. Noble, D. Hollingworth, S. Martin, Valerie Ennis-Adeniran +4 more
2005Nature Structural &Molecular Biology122 citations
Semantic Scholar
The structure of the C-terminal KH domains of KSRP reveals a noncanonical motif important for mRNA degradation.
M. García-Mayoral, D. Hollingworth, L. Masino, I. Díaz-Moreno +5 more
2007Structure121 citations Open access
Semantic Scholar
Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity
Nicolas Léveillé, Ran Elkon, V. Davalos, Vijayalaxmi Manoharan +10 more
2011Nature Communications112 citations Open access
Semantic Scholar
The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
A. Ramos, D. Hollingworth, S. Adinolfi, M. Castets +4 more
2006Structure112 citations Open access
Semantic Scholar
PHOSPHORYLATION-MEDIATED UNFOLDING OF A KH DOMAIN REGULATES KSRP LOCALISATION VIA 14-3-3 BINDING
I. Díaz-Moreno, D. Hollingworth, T. Frenkiel, G. Kelly +6 more
2009Nature Structural &Molecular Biology101 citations Open access
Semantic Scholar
The sequence selectivity of KSRP explains its flexibility in the recognition of the RNA targets
M. García-Mayoral, I. Díaz-Moreno, D. Hollingworth, A. Ramos
2008Nucleic Acids Research69 citations Open access
Semantic Scholar
Molecular basis of FIR-mediated c-myc transcriptional control
C. Cukier, D. Hollingworth, S. Martin, G. Kelly +2 more
2010Nature Structural &Molecular Biology65 citations Open access
Semantic Scholar
Cannabidiol interactions with voltage-gated sodium channels
L. G. Sait, A. Sula, Mohammad-Reza Ghovanloo, D. Hollingworth +2 more
2020bioRxiv60 citations Open access
Semantic Scholar
Mechanism of β-actin mRNA Recognition by ZBP1
G. Nicastro, A. M. Candel, Michael Uhl, A. Oregioni +4 more
2017Cell Reports56 citations Open access
Semantic Scholar
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets
I. Díaz-Moreno, D. Hollingworth, G. Kelly, Stephen R. Martin +4 more
2010Nucleic Acids Research41 citations Open access
Semantic Scholar
Role of dimerization in KH/RNA complexes: the example of Nova KH3.
A. Ramos, D. Hollingworth, Sarah Major, S. Adinolfi +3 more
2002Biochemistry38 citations
Semantic Scholar
Non-canonical Guanine recognition mediates KSRP regulation of Let-7 biogenesis
G. Nicastro, M. García-Mayoral, D. Hollingworth, G. Kelly +4 more
2012Nature Structural &Molecular Biology33 citations Open access
Semantic Scholar
RNA polymerase II CTD phosphopeptides compete with RNA for the interaction with Pcf11.
D. Hollingworth, C. Noble, I. Taylor, A. Ramos
2006RNA: A publication of the RNA Society31 citations Open access
Semantic Scholar
Mapping the interfaces of protein-nucleic acid complexes usingcross-saturation
A. Ramos, G. Kelly, D. Hollingworth, A. Pastore +1 more
200030 citations
Semantic Scholar
A tamoxifen receptor within a voltage-gated sodium channel
A. Sula, D. Hollingworth, Leo C. T. Ng, Megan Larmore +2 more
2021Molecules and Cells29 citations Open access
Semantic Scholar
The role of a clinically important mutation in the fold and RNA-binding properties of KH motifs.
A. Ramos, D. Hollingworth, A. Pastore
2003RNA: A publication of the RNA Society22 citations Open access
Semantic Scholar
Structural basis for the rescue of hyperexcitable cells by the amyotrophic lateral sclerosis drug Riluzole
D. Hollingworth, F. Thomas, Dana A Page, Mohamed A. Fouda +7 more
2024Nature Communications21 citations Open access
Semantic Scholar
Secondary structure and stability of the selenocysteine insertion sequences (SECIS) for human thioredoxin reductase and glutathione peroxidase.
A. Ramos, A. Lane, D. Hollingworth, T. Fan
2004Nucleic Acids Research8 citations Open access
Semantic Scholar
Functionally important binding site for a volatile anesthetic in a voltage-gated sodium channel identified by X-ray crystallography
D. Hollingworth, K. Herold, Geoff Kelly, V. Mykhaylyk +4 more
2024bioRxiv1 citations Open access
Semantic Scholar
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8 Angstrom resolution)
A. Sula, D. Hollingworth, B. Wallace
20211 citations
Semantic Scholar
Author response: Cannabidiol interactions with voltage-gated sodium channels
L. G. Sait, A. Sula, Mohammad-Reza Ghovanloo, D. Hollingworth +2 more
20201 citations Open access
Semantic Scholar
Backbone assignment of PCF11 CTD binding domain.
D. Hollingworth, G. Kelly, T. Frenkiel, C. Noble +2 more
2005Journal of Biomolecular NMR1 citations
Semantic Scholar
Volatile anaesthetics modulate voltage-gated sodium channel function at a site directly linked to channel gating
D. Hollingworth, K. Herold, Geoff Kelly, V. Mykhaylyk +2 more
2026Nature Communications0 citations Open access
Semantic Scholar
Tamoxifen complexes with the voltage-gated sodium channel reveal novel drug binding sites
D. Hollingworth, B. Wallace, A. Sula
2022Biophysical Journal0 citations Open access
Semantic Scholar
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution)
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) (2.2 Angstrom resolution)
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Crystal structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with 4-hydroxytamoxifen (2.5 Angstrom resolution)
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Full length Mutant Open-form Sodium Channel NavMs
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Crystal Structure of the Voltage-Gated Sodium Channel NavMs in complex with 4-hydroxytamoxifen (2.4 Angstrom resolution)
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Endoxifen (2.6 Angstrom resolution)
A. Sula, D. Hollingworth, B. Wallace
20210 citations
Semantic Scholar
Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD)
A. Sula, L. G. Sait, D. Hollingworth, B. Wallace
20200 citations
Semantic Scholar
Full length Open-form Sodium Channel NavMs F208L
A. Sula, L. G. Sait, D. Hollingworth, B. Wallace
20200 citations
Semantic Scholar
Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the RNA target CACACCC
G. Nicastro, A. M. Candel, A. Ramos, D. Hollingworth
20170 citations
Semantic Scholar
Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the RNA target UCGGACU
G. Nicastro, A. Ramos, A. M. Candel, D. Hollingworth
20170 citations
Semantic Scholar
Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target
G. Nicastro, A. M. Candel, A. Ramos, D. Hollingworth
20170 citations
Semantic Scholar
RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence.
G. Nicastro, M. García-Mayoral, D. Hollingworth, G. Kelly +4 more
20120 citations
Semantic Scholar
Solution structure of the first two RRM domains of FBP-interacting repressor (FIR)
C. Cukier, A. Ramos, D. Hollingworth, I. Díaz-Moreno +1 more
20100 citations
Semantic Scholar
Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide
C. Cukier, A. Ramos, D. Hollingworth, I. Díaz-Moreno +1 more
20100 citations
Semantic Scholar
Solution NMR Structure of the Second and Third KH Domains of KSRP
I. Díaz-Moreno, D. Hollingworth, M. García-Mayoral, G. Kelly +3 more
20090 citations
Semantic Scholar
Solution NMR Structure of the First Domain of KSRP
I. Díaz-Moreno, A. Ramos, M. García-Mayoral, D. Hollingworth
20080 citations
Semantic Scholar
Solution NMR Structure of the Second Domain of KSRP
I. Díaz-Moreno, A. Ramos, M. García-Mayoral, D. Hollingworth
20080 citations
Semantic Scholar
Structure of the N-terminal domain of Fragile X Mental Retardation Protein
A. Ramos, D. Hollingworth, S. Adinolfi, M. Castets +4 more
20060 citations
Semantic Scholar
Letters to the Editor
D. Hollingworth, G. Kelly, T. Frenkiel, C. Noble +2 more
20050 citations
Semantic Scholar
crystal structure of the rpr of pcf11
C. Noble, D. Hollingworth, S. Martin, V. E. Adeniran +4 more
20050 citations
Semantic Scholar
Mechanism of b-actin mRN A Recognition by ZBP 1 Graphical Abstract Highlights
G. Nicastro, A. M. Candel, Michael Uhl, A. Oregioni +4 more
0 citations
Semantic Scholar

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