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O. Rosen · SciRah

Researcher profile · Semantic Scholar

O. Rosen

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O. Rosen — researcher profile on SciRah

h-index: 48
Works: 125
Citations: 9,020

Most-cited papers

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
A. Ullrich, J. R. Bell, E. Chen, R. Herrera +11 more
1985Nature1,922 citations
Semantic Scholar
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.
C.-K. Chou, Thomas J. Dull, D. S. Russell, R. Gherzi +3 more
1987Journal of Biological Chemistry474 citations Open access
Semantic Scholar
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.
M. Birnbaum, H. Haspel, O. Rosen
1986Proceedings of the National Academy of Sciences of the United States of America451 citations Open access
Semantic Scholar
Phosphorylation activates the insulin receptor tyrosine protein kinase.
O. Rosen, R. Herrera, Y. Olowe, L. Petruzzelli +1 more
1983Proceedings of the National Academy of Sciences of the United States of America368 citations Open access
Semantic Scholar
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.
R. Ballester, O. Rosen
1985Journal of Biological Chemistry290 citations Open access
Semantic Scholar
Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription.
M. J. Birnbaum, H. Haspel, O. Rosen
1987Science276 citations
Semantic Scholar
Growth factors rapidly induce expression of the glucose transporter gene.
Y. Hiraki, O. Rosen, M. Birnbaum
1988Journal of Biological Chemistry241 citations Open access
Semantic Scholar
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.
M. Makowske, R. Ballester, Y. Cayre, O. Rosen
1988Journal of Biological Chemistry211 citations Open access
Semantic Scholar
Glucose transporters serve as water channels.
J. Fischbarg, K. Kuang, J. Vera, Suzanne Arant +3 more
1990Proceedings of the National Academy of Sciences of the United States of America196 citations Open access
Semantic Scholar
Acquisition of increased hormone sensitivity during in vitro adipocyte development.
C. Rubin, E. Lai, O. Rosen
1977Journal of Biological Chemistry161 citations Open access
Semantic Scholar
Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A.
S. Majumdar, M. W. Rossi, T. Fujiki, Wayne A. Phillips +6 more
1991Journal of Biological Chemistry145 citations Open access
Semantic Scholar
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor.
L. Stadtmauer, O. Rosen
1986Journal of Biological Chemistry140 citations
Semantic Scholar
Glucose deprivation and hexose transporter polypeptides of murine fibroblasts.
H. Haspel, E. Wilk, Morris J. Birnbaum, S. W. Cushman +1 more
1986Journal of Biological Chemistry135 citations Open access
Semantic Scholar
Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle.
R. Rangel-Aldao, O. Rosen
1976Journal of Biological Chemistry135 citations
Semantic Scholar
Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein.
H. Haspel, M. Rosenfeld, O. Rosen
1988Journal of Biological Chemistry117 citations Open access
Semantic Scholar
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation.
D. S. Russell, R. Gherzi, E. L. Johnson, C.-K. Chou +1 more
1987Journal of Biological Chemistry116 citations Open access
Semantic Scholar
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product.
R. Ballester, M. Furth, O. Rosen
1987Journal of Biological Chemistry112 citations Open access
Semantic Scholar
Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.
L. Petruzzelli, R. Herrera, R. Arenas-Garcia, R. Fernandez +2 more
1986Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
Resolution of the phosphorylated and dephosphorylated cAMP-binding proteins of bovine cardiac muscle by affinity labeling and two-dimensional electrophoresis.
R. Rangel-Aldao, J. Kupiec, O. Rosen
1979Journal of Biological Chemistry104 citations
Semantic Scholar
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation.
R. Herrera, O. Rosen
1986Journal of Biological Chemistry101 citations Open access
Semantic Scholar
Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.
C. L. le Peuch, R. Ballester, O. Rosen
1983Proceedings of the National Academy of Sciences of the United States of America99 citations Open access
Semantic Scholar
Phosphorylation of exogenous substrates by the insulin receptor-associated protein kinase.
L. Stadtmauer, O. Rosen
1983Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Tunicamycin‐mediated depletion of insulin receptors in 3T3‐L1 adipocytes
O. Rosen, G. H. Chia, C. Fung, C. Rubin
1979Journal of Cellular Physiology94 citations
Semantic Scholar
Structure and ligand specificity of the Drosophila melanogaster insulin receptor
R. Fernandez-Almonacid, O. Rosen
1987Molecular and Cellular Biology91 citations Open access
Semantic Scholar
Mechanism of self-phosphorylation of adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle.
R. Rangel-Aldao, O. Rosen
1976Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Effect of cAMP and ATP on the reassociation of phosphorylated and nonphosphorylated subunits of the cAMP-dependent protein kinase from bovine cardiac muscle.
R. Rangel-Aldao, O. Rosen
1977Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Tissue localization of Drosophila melanogaster insulin receptor transcripts during development
R. Garofalo, O. Rosen
1988Molecular and Cellular Biology79 citations Open access
Semantic Scholar
Purification of phosphoprotein phosphatase from bovine cardiac muscle that catalyzes dephosphorylation of cyclic AMP-binding protein component of protein kinase.
Chen K. Chou, J. Alfano, O. Rosen
1977Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes.
O. Rosen, Charles J. Smith, C. Fung, C. Rubin
1978Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis.
L. Petruzzelli, R. Herrera, R. Garcia-Arenas, O. Rosen
1985Journal of Biological Chemistry76 citations
Semantic Scholar
Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope.
M. Makowske, O. Rosen
1989Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Dexamethasone regulates the beta-adrenergic receptor subtype expressed by 3T3 L1 preadipocytes and adipocytes.
E. Lai, O. Rosen, C. Rubin
1982Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Description of a protein kinase derived from insulin-treated 3T3-L1 cells that catalyzes the phosphorylation of ribosomal protein S6 and casein.
Melanie H. Cobb, O. Rosen
1983Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Synthesis, purification, and characterization of the cytoplasmic domain of the human insulin receptor using a baculovirus expression system.
R. Herrera, D. Lebwohl, A. G. de Herreros, R. Kallen +1 more
1988Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Purification of a phosphoinositide-specific phospholipase C from bovine brain.
M. Rebecchi, O. Rosen
1987Journal of Biological Chemistry68 citations Open access
Semantic Scholar
The role of insulin receptor autophosphorylation in signal transduction.
M. Murakami, O. Rosen
1991Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Insulin and insulinlike growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits
R. Garofalo, O. Rosen
1989Molecular and Cellular Biology67 citations Open access
Semantic Scholar
Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes.
H. Haspel, Morris J. Birnbaum, E. Wilk, O. Rosen
1985Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Latent insulin receptors and possible receptor precursors in 3T3-L1 adipocytes.
P. Deutsch, Catherine F. Wan, O. Rosen, C. Rubin
1983Proceedings of the National Academy of Sciences of the United States of America61 citations Open access
Semantic Scholar
Drosophila cAMP-dependent protein kinase.
J. L. Foster, J. Guttman, L. M. Hall, O. Rosen
1984Journal of Biological Chemistry60 citations
Semantic Scholar
Genetic analysis of the role of cAMP in mediating effects of interferon.
J. Schneck, Bracha Rager-Zisman, O. Rosen, Barry R. Bloom
1982Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Structure and Function of Insulin Receptors
O. Rosen
1989Diabetes56 citations
Semantic Scholar
Self-phosphorylation of cyclic guanosine 3':5'-monophosphate-dependent protein kinase from bovine lung. Effect of cyclic adenosine 3':5'-monophosphate, cyclic guanosine 3':5'-monophosphate and histone.
H. D. de Jonge, O. Rosen
1977Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Functional expression of mammalian glucose transporters in Xenopus laevis oocytes: evidence for cell-dependent insulin sensitivity
J. C. Vera, O. Rosen
1989Molecular and Cellular Biology52 citations Open access
Semantic Scholar
Regulation of fatty acid synthetase concentration and activity during adipocyte differentiation. Studies on 3T3-L1 cells.
G. Weiss, O. Rosen, C. Rubin
1980Journal of Biological Chemistry52 citations Open access
Semantic Scholar
A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells.
M. Makowske, M. J. Birnbaum, R. Ballester, O. Rosen
1986Journal of Biological Chemistry51 citations Open access
Semantic Scholar
An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity.
R. Herrera, L. Petruzzelli, N. Thomas, H. N. Bramson +2 more
1985Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Purification of a bovine liver S6 kinase.
Diane Tabarini, Antonio García de Herreros, Julia Heinrich, O. Rosen
1987Biochemical and Biophysical Research Communications - BBRC45 citations
Semantic Scholar
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.
R. Gherzi, D. S. Russell, Simeon I. Taylor, O. Rosen
1987Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Another version of the human insulin receptor kinase domain: expression, purification, and characterization.
M. Villalba, S. Wente, David S. Russell, Jongcheol Ahn +2 more
1989Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar

Frequent co-authors

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R. Herrera×7
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R. Herrera — researcher profile on SciRah
C. Rubin×6
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L. Petruzzelli×5
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H. Haspel×5
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R. Rangel-Aldao×4

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M. Birnbaum — researcher profile on SciRah

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