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B. Larsen · SciRah

Researcher profile · Semantic Scholar

B. Larsen

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B. Larsen — researcher profile on SciRah

h-index: 22
Works: 69
Citations: 1,320

Most-cited papers

Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).
L. Axelsen, M. Stahlhut, S. Mohammed, B. Larsen +6 more
2006Journal of Molecular and Cellular Cardiology144 citations
Semantic Scholar
Glucagon-Like Peptide 1 Receptor Agonist ZP10A Increases Insulin mRNA Expression and Prevents Diabetic Progression in db/db Mice
C. Thorkildsen, S. Neve, B. Larsen, E. Meier +1 more
2003Journal of Pharmacology and Experimental Therapeutics99 citations
Semantic Scholar
Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs
J. Hennan, R. Swillo, G. A. Morgan, J. Keith +10 more
2006Journal of Pharmacology and Experimental Therapeutics97 citations
Semantic Scholar
Pharmacological Characterization of the New Stable Antiarrhythmic Peptide Analog Ac-d-Tyr-d-Pro-d-Hyp-Gly-d-Ala-Gly-NH2 (ZP123): In Vivo and in Vitro Studies
A. Kjølbye, Carsten Knudsen, T. Jepsen, B. Larsen +1 more
2003Journal of Pharmacology and Experimental Therapeutics76 citations
Semantic Scholar
Genome‐Wide Association Studies in Apple Reveal Loci for Aroma Volatiles, Sugar Composition, and Harvest Date
B. Larsen, Zoë Migicovsky, Anne Aae Jeppesen, Kyle M. Gardner +5 more
2019The Plant Genome74 citations Open access
Semantic Scholar
Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21.
R. Possenti, G. Muccioli, Pamela Petrocchi, C. Cero +23 more
2012Biochemical Journal61 citations
Semantic Scholar
Incomplete Fmoc deprotection in solid-phase synthesis of peptides.
B. Larsen, A. Holm
2009International journal of peptide & protein research51 citations
Semantic Scholar
Effects of the New Antiarrhythmic Peptide ZP123 on Epicardial Activation and Repolarization Pattern
S. Dhein, B. Larsen, J. Petersen, F. Mohr
2003Cell Communication & Adhesion51 citations Open access
Semantic Scholar
Population structure, relatedness and ploidy levels in an apple gene bank revealed through genotyping-by-sequencing
B. Larsen, Kyle M. Gardner, C. Pedersen, M. Ørgaard +3 more
2018PLoS ONE47 citations Open access
Semantic Scholar
Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice
A. Rizzi, Daniela Rizzi, G. Marzola, D. Regoli +3 more
2002British Journal of Pharmacology47 citations Open access
Semantic Scholar
Unravelling genetic diversity and cultivar parentage in the Danish apple gene bank collection
B. Larsen, T. Toldam-Andersen, C. Pedersen, M. Ørgaard
2017Tree Genetics & Genomes44 citations
Semantic Scholar
Gap junction modifier rotigaptide decreases the susceptibility to ventricular arrhythmia by enhancing conduction velocity and suppressing discordant alternans during therapeutic hypothermia in isolated rabbit hearts.
Yu-Cheng Hsieh, Jiunn-cherng Lin, Chen-Ying Hung, Cheng-Hung Li +7 more
2016Heart Rhythm42 citations
Semantic Scholar
Discovery of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride (GAP-134)13, an orally active small molecule gap-junction modifier for the treatment of atrial fibrillation.
J. Butera, B. Larsen, J. Hennan, E. Kerns +11 more
2009Journal of Medicinal Chemistry41 citations
Semantic Scholar
N-terminal 4-imidazolidinone prodrugs of Leu-enkephalin: synthesis, chemical and enzymatic stability studies.
A. Bak, Mette Fich, B. Larsen, Sven Frokjaer +1 more
1999European Journal of Pharmaceutical Sciences41 citations
Semantic Scholar
The Merrifield peptide synthesis studied by near-infrared Fourier-transform Raman spectroscopy
B. Larsen, D. Christensen, A. Holm, R. Zillmer +1 more
199339 citations
Semantic Scholar
A high-throughput method for genotyping S-RNase alleles in apple
B. Larsen, M. Ørgaard, T. Toldam-Andersen, C. Pedersen
2016Molecular breeding33 citations Open access
Semantic Scholar
Novel Pharmacophores of Connexin43 Based on the “RXP” Series of Cx43-binding Peptides
Vandana Verma, B. Larsen, W. Coombs, Xianming Lin +4 more
2009Circulation Research32 citations Open access
Semantic Scholar
Inhibition of Cx43 gap junction uncoupling prevents high glucose‐induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells
Dongjoon Kim, U. Mouritzen, B. Larsen, Sayon Roy
2018Experimental Eye Research31 citations
Semantic Scholar
The design and discovery of lixisenatide for the treatment of type 2 diabetes mellitus
M. Christensen, P. Miossec, B. Larsen, U. Werner +1 more
2014Expert Opinion on Drug Discovery31 citations
Semantic Scholar
Large intraspecific genetic variation within the Saffron-Crocus group (Crocus L., Series Crocus; Iridaceae)
B. Larsen, J. Orabi, C. Pedersen, M. Ørgaard
2014Plant Systematics and Evolution25 citations
Semantic Scholar
Design and characterization of the first peptidomimetic molecule that prevents acidification-induced closure of cardiac gap junctions
Vandana Verma, B. Larsen, W. Coombs, Xianming Lin +3 more
2010Heart Rhythm24 citations Open access
Semantic Scholar
Sequence-assisted peptide synthesis (SAPS).
B. Larsen, A. Holm
2009Journal of Peptide Research22 citations
Semantic Scholar
Stability, metabolism and transport of D-Asp(OBzl)-Ala--a model prodrug with affinity for the oligopeptide transporter.
Bente Steffansen, Eve-Irene Lepist, M. Taub, B. Larsen +2 more
1999European Journal of Pharmaceutical Sciences18 citations
Semantic Scholar
Osteoclastogenesis is Influenced by Modulation of Gap Junctional Communication with Antiarrhythmic Peptides
Elina Kylmäoja, H. Kokkonen, K. Kauppinen, P. Hussar +4 more
2012Calcified Tissue International16 citations
Semantic Scholar
Photolysis of 1,2,3-thiadiazole. Formation of thiirene by secondary photolysis of thioketene
B. Larsen, H. Eggert, N. Harrit, A. Holm +3 more
199216 citations Open access
Semantic Scholar
β-Carboxylic acid esterified D-Asp-Ala retains a high affinity for the oligopeptide transporter in Caco-2 monolayers
M. Taub, B. Larsen, B. Steffansen, S. Frokjaer
199714 citations
Semantic Scholar
Glepaglutide, a novel glucagon-like peptide-2 agonist, has anti-inflammatory and mucosal regenerative effects in an experimental model of inflammatory bowel disease in rats
J. Skarbaliene, J. M. Mathiesen, B. Larsen, C. Thorkildsen +1 more
2023BMC Gastroenterology12 citations Open access
Semantic Scholar
MONITORING OF A SOLID PHASE PEPTIDE SYNTHESIS BY NIR-FT-RAMAN SPECTROSCOPY
J. Ryttersgaard, B. Larsen, A. Holm, D. Christensen +1 more
199712 citations
Semantic Scholar
Pharmacological characterization of the new stable antiarrhythmic peptide analogue ZP 123 : In vivo and in vitro studies
A. Kjølbye, Carsten Knudsen, T. Jepsen, B. Larsen +1 more
20038 citations
Semantic Scholar
Glucagon-Like Peptide 1 Receptor Agonist ZP 10 A Increases Insulin mRNA Expression and Prevents Diabetic Progression in db / db Mice
C. Thorkildsen, S. Neve, B. Larsen, E. Meier +1 more
20038 citations
Semantic Scholar
Prodrugs of peptides obtained by derivatization of the C-terminal peptide bond in order to effect protection against degradation by carboxypeptidases
G. Friis, A. Bak, B. Larsen, S. Frokjaer
19968 citations
Semantic Scholar
Photolysis of 1,2,3-selenadiazole. Formation of selenirene by secondary photolysis of selenoketene
N. Harrit, Steen Rosenkilde, B. Larsen, A. Holm
19857 citations
Semantic Scholar
Recurrent hybridisation events between Primula vulgaris , P . veris and P . elatior (Primulaceae, Ericales) challenge the species boundaries: using molecular markers to re-evaluate morphological identifications
K. Tendal, M. Ørgaard, B. Larsen, C. Pedersen
2018Nordic Journal of Botany6 citations
Semantic Scholar
Discovery of a class of potent gap-junction modifiers as novel antiarrhythmic agents.
Eugene L. Piatnitski Chekler, J. Butera, L. Di, R. Swillo +5 more
2009Bioorganic & Medicinal Chemistry Letters5 citations
Semantic Scholar
Photochemical conjugation of peptides to carrier proteins using 1,2,3-thiadiazole-4-carboxylic acid. Immunoreactivity of free C-terminal epitope with specific antibodies.
P. R. Hansen, Hanne Flyge, A. Holm, E. Lauritzen +1 more
2009International journal of peptide & protein research5 citations
Semantic Scholar
Primula farinosa in Denmark; genetic diversity and population management
S. Sørensen, B. Larsen, J. Orabi, M. Ørgaard
20144 citations
Semantic Scholar
STRUCTURAL INDUCING PROBES (SIP) - BLOWS NEW HOPE INTO THE GENERAL USE OF PEPTIDES AS DRUGS.
B. Larsen, L. H. Jensen, N. Mørk, M. Bjerrum +3 more
20004 citations
Semantic Scholar
Incomplete Fmoc-deprotection in solid phase peptide synthesis
B. Larsen, Ch. Larsen, A. Holm
19914 citations
Semantic Scholar
PHOTOLYSIS OF 1,2,3‐SELENADIAZOLE. FORMATION OF SELENIRENE BY SECONDARY PHOTOLYSIS OF SELENOKETENE
N. Harrit, Steen Rosenkilde, B. Larsen, A. Holm
19854 citations
Semantic Scholar
Creating Glepaglutide, the First Long-Acting GLP-2 Analogue to Enable a Ready-to-Use Injection.
B. Larsen, Jesper Skodborg Villadsen, Jolanta Skarbaliene, Claes Melander +3 more
2025Journal of Medicinal Chemistry3 citations
Semantic Scholar
Ventricular divergence correlates with epicardial wavebreaks and predicts ventricular arrhythmia in isolated rabbit hearts during therapeutic hypothermia
Yu-Cheng Hsieh, W. Hsieh, Cheng-Hung Li, Ying-Chieh Liao +13 more
2020PLoS ONE3 citations Open access
Semantic Scholar
S-allele frequency and genetic diversity of Malus orientalis Uglitzk along an altitudinal gradient in the Hyrcanian forest
H. Yousefzadeh, R. Rajaei, B. Larsen, H. Bina +1 more
2020Forest Systems2 citations Open access
Semantic Scholar
Photolysis of N-2,4,6-trinitrophenyl substituted amino acids
J. Frederiksen, B. Larsen, N. Harrit
19912 citations
Semantic Scholar
1685-P: Dapiglutide Is a Dual Agonist on Human GLP-1- and GLP-2-Receptors with a Biased and Prolonged Signaling Profile at the GLP-1R
Louise Gjelstrup, Betina Kerstin Lundholt, B. Larsen, N. Johansen +2 more
2024Diabetes1 citations
Semantic Scholar
Administration of a gap junction coupler reduces retinal vascular cell loss associated with diabetic retinopathy
Dongjoon Kim, Dayeun Lee, U. Mouritzen, B. Larsen +1 more
20171 citations
Semantic Scholar
Danish apple cultivars: genetic diversity, parentage and breeding potential
B. Larsen, C. Pedersen, M. Ørgaard, T. Toldam-Andersen
20171 citations
Semantic Scholar
Sequence assisted peptide synthesis (SAPS): A structural evaluation of the technology
B. Larsen, A. Holm, D. Christensen, O. Nielsen
20021 citations
Semantic Scholar
4.19 – 1,2,3,4-Thiatriazoles
A. Holm, B. Larsen
19961 citations
Semantic Scholar
Creating Glepaglutide: The First Long-Acting GLP-2 Analogue to enable a Ready-to-Use Subcutaneous Injection
B. Larsen, Jesper Villadsen, Jolanta Skarbaliene, Claes Melander +3 more
2025Intestinal Failure0 citations Open access
Semantic Scholar
Comments on “Pharmacological Characterization of Apraglutide a Novel Long-Acting Peptidic Glucagon-Like Peptide-2 Agonist for the Treatment of Short Bowel Syndrome”
J. Skarbaliene, B. Larsen, M. Berner-Hansen, A. Steensberg
2021Journal of Pharmacology and Experimental Therapeutics0 citations Open access
Semantic Scholar

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