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W. Coombs · SciRah

Researcher profile · Semantic Scholar

W. Coombs

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W. Coombs — researcher profile on SciRah

h-index: 22
Works: 39
Citations: 2,381

Most-cited papers

Loss of Plakophilin-2 Expression Leads to Decreased Sodium Current and Slower Conduction Velocity in Cultured Cardiac Myocytes
Priscila Y. Sato, H. Musa, W. Coombs, Guadalupe Guerrero-Serna +4 more
2009Circulation Research326 citations Open access
Semantic Scholar
Interactions between Ankyrin-G, Plakophilin-2 and Connexin43 at the cardiac intercalated disc
Priscila Y. Sato, W. Coombs, Xianming Lin, O. Nekrasova +4 more
2011Circulation Research247 citations Open access
Semantic Scholar
Connexin43 Remodeling Caused by Inhibition of Plakophilin-2 Expression in Cardiac Cells
Eva M. Oxford, H. Musa, Karen Maass, W. Coombs +2 more
2007Circulation Research246 citations Open access
Semantic Scholar
Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin43 Indicates Signaling between Binding Domains for c-Src and Zonula Occludens-1*
P. Sorgen, H. Duffy, P. Sahoo, W. Coombs +2 more
2004Journal of Biological Chemistry191 citations Open access
Semantic Scholar
pH-Dependent Intramolecular Binding and Structure Involving Cx43 Cytoplasmic Domains*
H. Duffy, P. Sorgen, M. Girvin, Phyllis M. O'Donnell +4 more
2002Journal of Biological Chemistry185 citations Open access
Semantic Scholar
PH regulation of connexin43: molecular analysis of the gating particle.
J. Ek-Vitorin, Guillermo Calero, Gregory E. Morley, W. Coombs +2 more
1996Biophysical Journal173 citations Open access
Semantic Scholar
Regulation of Connexin43 Protein Complexes by Intracellular Acidification
H. Duffy, A. Ashton, Phyllis M. O'Donnell, W. Coombs +3 more
2004Circulation Research134 citations Open access
Semantic Scholar
Structural bases for the chemical regulation of Connexin43 channels.
M. Delmar, W. Coombs, P. Sorgen, H. Duffy +1 more
2004Cardiovascular Research110 citations
Semantic Scholar
A particle-receptor model for the insulin-induced closure of connexin43 channels.
N. Homma, J. L. Alvarado, W. Coombs, K. Stergiopoulos +3 more
1998Circulation Research95 citations Open access
Semantic Scholar
Gap Junction Protein Cx37 Interacts With Endothelial Nitric Oxide Synthase in Endothelial Cells
Anna Pfenniger, Jean-Paul Derouette, Vandana Verma, Xianming Lin +9 more
2010Arteriosclerosis, Thrombosis and Vascular Biology83 citations Open access
Semantic Scholar
Molecular composition of the intercalated disc in a spontaneous canine animal model of arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Eva M. Oxford, M. Everitt, W. Coombs, Philip R. Fox +6 more
2007Heart Rhythm83 citations Open access
Semantic Scholar
Modifications in the Biophysical Properties of Connexin43 Channels by a Peptide of the Cytoplasmic Loop Region
A. Seki, H. Duffy, W. Coombs, D. Spray +2 more
2004Circulation Research73 citations Open access
Semantic Scholar
Characterization of the molecular phenotype of two ARVC-related PKP2 mutations
Rosy Joshi-Mukherjee, W. Coombs, H. Musa, Eva M. Oxford +2 more
2008Heart Rhythm61 citations Open access
Semantic Scholar
Loss of electrical communication, but not plaque formation, after mutations in the cytoplasmic loop of connexin43.
A. Seki, W. Coombs, S. Taffet, M. Delmar
2004Heart Rhythm60 citations
Semantic Scholar
Identification of a Novel Peptide That Interferes With the Chemical Regulation of Connexin43
Junko Shibayama, Rebecca Lewandowski, Fabien Kieken, W. Coombs +4 more
2006Circulation Research44 citations Open access
Semantic Scholar
Evidence for the Presence of a Free C-Terminal Fragment of Cx43 in Cultured Cells
Rosy Joshi-Mukherjee, W. Coombs, Christine M. Burrer, Isabel Alvarez de Mora +2 more
2007Cell Communication & Adhesion40 citations Open access
Semantic Scholar
Letter to the Editor: Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43
P. Sorgen, H. Duffy, S. Cahill, W. Coombs +3 more
2002Journal of Biomolecular NMR38 citations
Semantic Scholar
Immunohistochemical Localization of Gap Junction Protein Channels in Hamster Sinoatrial Node in Correlation with Electrophysiologic Mapping of the Pacemaker Region
E. Trabka-Janik, W. Coombs, L. Lemanski, M. Delmar +1 more
1994Cardiovascular Electrophysiology37 citations
Semantic Scholar
RXP-E: A CX43-BINDING PEPTIDE THAT PREVENTS ACTION POTENTIAL PROPAGATION BLOCK
Rebecca Lewandowski, Kristina Procida, R. Vaidyanathan, W. Coombs +4 more
2008Circulation Research34 citations Open access
Semantic Scholar
Novel Pharmacophores of Connexin43 Based on the “RXP” Series of Cx43-binding Peptides
Vandana Verma, B. Larsen, W. Coombs, Xianming Lin +4 more
2009Circulation Research32 citations Open access
Semantic Scholar
Spontaneous cardiac calcinosis in BALB/cByJ mice.
A. Glass, W. Coombs, S. Taffet
2013Comparative medicine25 citations
Semantic Scholar
Design and characterization of the first peptidomimetic molecule that prevents acidification-induced closure of cardiac gap junctions
Vandana Verma, B. Larsen, W. Coombs, Xianming Lin +3 more
2010Heart Rhythm24 citations Open access
Semantic Scholar
Functional Demonstration of Connexin—Protein Binding Using Surface Plasmon Resonance
H. Duffy, M. Delmar, W. Coombs, Steven M. Tafftet +2 more
2001Cell Communication & Adhesion13 citations Open access
Semantic Scholar
DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses
T. Keil, Dong-Mei Liu, M. Lloyd, W. Coombs +2 more
2020Frontiers in Microbiology10 citations Open access
Semantic Scholar
Surface Plasmon Resonance as a Method to Study the Kinetics and Amplitude of Protein- Protein Binding
B. Lang, M. Delmar, W. Coombs
20057 citations
Semantic Scholar
Chemical Gating of Connexin Channels
Rebecca Lewandowski, Junko Shibayama, Eva M. Oxford, Rosy Joshi-Mukherjee +4 more
20095 citations
Semantic Scholar
Kinetics of Protein-Protein Interactions of Connexins: Use of Enzyme Linked Sorbent Assays
H. Duffy, Phyllis M. O'Donnell, W. Coombs, S. Taffet +2 more
2003Cell Communication & Adhesion4 citations Open access
Semantic Scholar
Characterization of the molecular phenotype of two ARVC-related PKP2 mutations
Rosy Joshi-Mukherjee, W. Coombs, H. Musa, Eva M. Oxford +2 more
20091 citations
Semantic Scholar
Acidification-induced changes in Cx43 protein–protein interactions
H. Duffy, P. Sorgen, W. Coombs, S. Taffet +3 more
20081 citations Open access
Semantic Scholar
Microenvironment regulates antibody secretion by IgA+ plasma cells.
Victoria Zoccoli-Rodriguez, W. Coombs, Joshua Harris, Mara Delaney +1 more
2023Journal of Immunology0 citations Open access
Semantic Scholar
Severity of autoimmune myocarditis is influenced by Connexin43 expression (171.23)
A. Glass, W. Coombs, S. Taffet
2012Journal of Immunology0 citations
Semantic Scholar
Humanized mice and in vivo bioluminescence imaging: tools for testing antiviral drugs for varicella-zoster virus
J. Moffat, C. De, Dong-Mei Liu, N. Fiore +2 more
20110 citations
Semantic Scholar
Abstract 18393: Plakophilin-2, Ankyrin-G and Connexin43 Mutually Interact to Regulate Intercellular Coupling and Sodium Channel Function. Implications to Arrhythmogenic Cardiomyopathies?
Priscila Y. Sato, Xianming Lin, H. Musa, W. Coombs +3 more
20100 citations
Semantic Scholar
Abstract 2814: Loss of Plakophilin-2 Expression Leads to Decreased Sodium Current and Slower Conduction Velocity in Cultured Cardiac Myocytes
Priscila Y. Sato, H. Musa, W. Coombs, Guadalupe Guerrero-Serna +4 more
20090 citations
Semantic Scholar
Redefining The Interaction Domain Of Cx43CT With RXP-E And Cx43CL
Gaelle Spagnol, W. Coombs, S. Taffet, B. Larsen +2 more
20090 citations Open access
Semantic Scholar
Abstract 1911: eNOS is a Binding Partner for the Gap Junction Protein Cx37 in Endothelial Cells
Anna Pfenniger, Jean-Paul Derouette, Vandana Verma, B. Foglia +6 more
20080 citations
Semantic Scholar
Manipulation of gap junction proteins: effect on cellular coupling and impulse propagation
S. Taffet, S. Shah, Rebecca Lewandowski, W. Coombs +3 more
20050 citations
Semantic Scholar
Symposium S6: Junctional Complexes in the Nervous System in Health & Disease
H. Duffy, A. Ashton, W. Coombs, S. Taffet +11 more
20040 citations
Semantic Scholar
Connexin 43 Carboxyl Terminal Domain
P. Sorgen, H. Duffy, D. Mario, P. Sahoo +3 more
20040 citations
Semantic Scholar

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