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S. Frokjaer · SciRah

Researcher profile · Semantic Scholar

S. Frokjaer

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S. Frokjaer — researcher profile on SciRah

h-index: 37
Works: 119
Citations: 7,271

Most-cited papers

Effect of environmental factors on the kinetics of insulin fibril formation: elucidation of the molecular mechanism.
Liza Nielsen, R. Khurana, Alisa C. Coats, S. Frokjaer +4 more
2001Biochemistry1,148 citations
Semantic Scholar
Protein drug stability: a formulation challenge
S. Frokjaer, D. Otzen
2005Nature reviews. Drug discovery1,069 citations
Semantic Scholar
Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model.
C. Foged, B. Brodin, S. Frokjaer, A. Sundblad
2005International journal of pharmaceutics879 citations
Semantic Scholar
A Helical Structural Nucleus Is the Primary Elongating Unit of Insulin Amyloid Fibrils
B. Vestergaard, M. Groenning, M. Roessle, J. Kastrup +5 more
2007PLoS Biology255 citations Open access
Semantic Scholar
Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII.
Lotte Krielgaard, Latoya S. Jones, T. Randolph, S. Frokjaer +3 more
1998Journal of Pharmacy and Science242 citations
Semantic Scholar
Study on the binding of Thioflavin T to β-sheet-rich and non- β-sheet cavities
M. Groenning, L. Olsen, M. van de Weert, J. Flink +2 more
2007232 citations
Semantic Scholar
Binding mode of Thioflavin T in insulin amyloid fibrils.
M. Groenning, M. Norrman, J. Flink, M. van de Weert +3 more
2007Journal of Structural Biology227 citations
Semantic Scholar
Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition.
C. Foged, C. Arigita, A. Sundblad, W. Jiskoot +2 more
2004Vaccine209 citations
Semantic Scholar
Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
D. K. Jensen, Dongmei Cun, M. Maltesen, S. Frokjaer +2 more
2009Journal of Controlled Release197 citations Open access
Semantic Scholar
Intestinal solute carriers: an overview of trends and strategies for improving oral drug absorption.
B. Steffansen, C. U. Nielsen, B. Brodin, A. H. Eriksson +2 more
2004European Journal of Pharmaceutical Sciences149 citations
Semantic Scholar
Thermal dissociation and unfolding of insulin.
Kasper Huus, S. Havelund, H. Olsen, M. van de Weert +1 more
2005Biochemistry134 citations
Semantic Scholar
Transport of peptidomimetic drugs by the intestinal Di/tri-peptide transporter, PepT1.
B. Brodin, C. U. Nielsen, B. Steffansen, S. Frokjaer
2002Acta Pharmacologica et Toxicologica129 citations Open access
Semantic Scholar
Preparation and characterization of poly(DL-lactide-co-glycolide) nanoparticles for siRNA delivery.
Dongmei Cun, C. Foged, Ming-Shi Yang, S. Frokjaer +1 more
2010International journal of pharmaceutics108 citations
Semantic Scholar
Pharmaceutical Formulation Development Of Peptides And Proteins
L. Hovgaard, S. Frokjaer, M. van de Weert
2009103 citations
Semantic Scholar
Calcipotriol delivery into the skin with PEGylated liposomes.
N. Knudsen, S. Rønholt, R. Salte, L. Jorgensen +5 more
2012European journal of pharmaceutics and biopharmaceutics94 citations
Semantic Scholar
Loading into and electro-stimulated release of peptides and proteins from chondroitin 4-sulphate hydrogels.
M. Jensen, Pernille Birch Hansen, S. Murdan, S. Frokjaer +1 more
2002European Journal of Pharmaceutical Sciences83 citations
Semantic Scholar
Prediction of the association state of insulin using spectral parameters.
V. Uversky, L. Garriques, I. Millett, S. Frokjaer +3 more
2003Journal of Pharmacy and Science80 citations
Semantic Scholar
Interfacial adsorption of insulin conformational changes and reversibility of adsorption.
S. Mollmann, L. Jorgensen, J. Bukrinsky, U. Elofsson +2 more
2006European Journal of Pharmaceutical Sciences77 citations Open access
Semantic Scholar
Optimized conditions for MDCK permeability and turbidimetric solubility studies using compounds representative of BCS classes I-IV.
M. Taub, L. Kristensen, S. Frokjaer
2002European Journal of Pharmaceutical Sciences77 citations
Semantic Scholar
Liposomes for phospholipase A2 triggered siRNA release: preparation and in vitro test.
C. Foged, Hanne M Nielsen, S. Frokjaer
2007International journal of pharmaceutics59 citations
Semantic Scholar
Study on the binding of Thioflavin T to beta-sheet-rich and non-beta-sheet cavities.
M. Groenning, L. Olsen, M. van de Weert, J. Flink +2 more
2007Journal of Structural Biology58 citations
Semantic Scholar
Release of chemical permeation enhancers from drug-in-adhesive transdermal patches.
M. H. Qvist, U. Hoeck, B. Kreilgaard, F. Madsen +1 more
2002International journal of pharmaceutics57 citations
Semantic Scholar
Complex Coacervation of Lysozyme and Heparin: Complex Characterization and Protein Stability
M. van de Weert, M. Andersen, S. Frokjaer
2004Pharmaceutical Research56 citations
Semantic Scholar
Displacement of Adsorbed Insulin by Tween 80 Monitored Using Total Internal Reflection Fluorescence and Ellipsometry
S. Mollmann, U. Elofsson, J. Bukrinsky, S. Frokjaer
2005Pharmaceutical Research55 citations
Semantic Scholar
Drug delivery by phospholipase A(2) degradable liposomes.
J. Davidsen, C. Vermehren, S. Frokjaer, O. G. Mouritsen +1 more
2001International journal of pharmaceutics54 citations
Semantic Scholar
Adsorption of human insulin and AspB28 insulin on a PTFE-like surface.
S. Mollmann, J. Bukrinsky, S. Frokjaer, U. Elofsson
2005Journal of Colloid and Interface Science52 citations
Semantic Scholar
Cellular uptake and membrane-destabilising properties of alpha-peptide/beta-peptoid chimeras: lessons for the design of new cell-penetrating peptides.
C. Foged, H. Franzyk, S. Bahrami, S. Frokjaer +3 more
2008Biochimica et Biophysica Acta50 citations Open access
Semantic Scholar
Predicting Drug Absorption from Molecular Surface Properties Based on Molecular Dynamics Simulations
Lene Hjorth Krarup, I. Christensen, L. Hovgaard, S. Frokjaer
1998Pharmaceutical Research50 citations
Semantic Scholar
Probing structural changes of proteins incorporated into water-in-oil emulsions.
L. Jorgensen, M. van de Weert, C. Vermehren, S. Bjerregaard +1 more
2004Journal of Pharmacy and Science47 citations
Semantic Scholar
Human peptide transporters: therapeutic applications
C. U. Nielsen, B. Brodin, F. Jørgensen, S. Frokjaer +1 more
200244 citations
Semantic Scholar
Characterisation and physical stability of PEGylated glucagon.
Pernille Stigsnaes, S. Frokjaer, S. Bjerregaard, M. van de Weert +2 more
2007International journal of pharmaceutics42 citations Open access
Semantic Scholar
Data-enriched edible pharmaceuticals (DEEP) of medical cannabis by inkjet printing.
Heidi Öblom, C. Cornett, J. Bøtker, S. Frokjaer +4 more
2020International journal of pharmaceutics41 citations Open access
Semantic Scholar
Factors of importance for a successful delivery system for proteins
M. van de Weert, L. Jorgensen, Eva Horn Moeller, S. Frokjaer
2005Expert Opinion on Drug Delivery41 citations
Semantic Scholar
In-depth evaluation of Gly-Sar transport parameters as a function of culture time in the Caco-2 cell model.
Silvina A Bravo, C. U. Nielsen, J. Amstrup, S. Frokjaer +1 more
2004European Journal of Pharmaceutical Sciences40 citations
Semantic Scholar
Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity.
N. Knudsen, L. Jorgensen, Jens Hansen, C. Vermehren +2 more
2011International journal of pharmaceutics39 citations
Semantic Scholar
Chemical and Thermal Stability of Insulin: Effects of Zinc and Ligand Binding to the Insulin Zinc-Hexamer
Kasper Huus, S. Havelund, H. Olsen, M. van de Weert +1 more
2006Pharmaceutical Research35 citations
Semantic Scholar
Effects of sucrose on rFVIIa aggregation and methionine oxidation.
S. Soenderkaer, J. Carpenter, M. van de Weert, L. L. Hansen +2 more
2004European Journal of Pharmaceutical Sciences35 citations
Semantic Scholar
Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces.
Charlotte Pinholt, J. Bukrinsky, Susanne Hostrup, S. Frokjaer +2 more
2011European journal of pharmaceutics and biopharmaceutics34 citations Open access
Semantic Scholar
Phase behavior and nanoscale structure of phospholipid membranes incorporated with acylated C14-peptides.
T. Pedersen, T. Kaasgaard, M. Jensen, S. Frokjaer +2 more
2005Biophysical Journal34 citations Open access
Semantic Scholar
Delivery aspects of small peptides and substrates for peptide transporters.
B. Steffansen, C. U. Nielsen, S. Frokjaer
2005European journal of pharmaceutics and biopharmaceutics34 citations
Semantic Scholar
Lung surfactant as a drug delivery system.
C. Vermehren, S. Frokjaer, T. Aurstad, Jens Hansen
2006International journal of pharmaceutics33 citations
Semantic Scholar
Ligand binding and thermostability of different allosteric states of the insulin zinc-hexamer.
Kasper Huus, S. Havelund, H. Olsen, B. Sigurskjold +2 more
2006Biochemistry29 citations
Semantic Scholar
Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism.
Anne Engelbrecht Thomsen, G. Friedrichsen, Arne Hagsten Sørensen, R. Andersen +5 more
2003Journal of Controlled Release27 citations Open access
Semantic Scholar
Transport Characteristics of L-Carnosine and the Anticancer Derivative 4-Toluenesulfonylureido-Carnosine in a Human Epithelial Cell Line
C. U. Nielsen, C. Supuran, A. Scozzafava, S. Frokjaer +2 more
2002Pharmaceutical Research26 citations
Semantic Scholar
Influence of glycosylation on the adsorption of Thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces.
Charlotte Pinholt, M. Fanø, C. Wiberg, Susanne Hostrup +4 more
2010European Journal of Pharmaceutical Sciences21 citations Open access
Semantic Scholar
Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2.
Silvina A Bravo, C. U. Nielsen, J. Amstrup, S. Frokjaer +1 more
2004AJP - Renal Physiology20 citations
Semantic Scholar
The effect of mutations on the structure of insulin fibrils studied by Fourier transform infrared (FTIR) spectroscopy and electron microscopy.
L. Garriques, S. Frokjaer, J. Carpenter, J. Brange
2002Journal of Pharmacy and Science20 citations
Semantic Scholar
Kinetics of Insulin Adsorption at the Oil–Water Interface and Diffusion Properties of Adsorbed Layers Monitored Using Fluorescence Correlation Spectroscopy
Jesper Donsmark, L. Jorgensen, S. Mollmann, S. Frokjaer +1 more
2006Pharmaceutical Research18 citations
Semantic Scholar
Influence of acylation on the adsorption of GLP-2 to hydrophobic surfaces.
Charlotte Pinholt, Sebastian J Kapp, J. Bukrinsky, Susanne Hostrup +3 more
2013International journal of pharmaceutics17 citations Open access
Semantic Scholar
Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin α₂β₁ receptor.
N. Knudsen, R. Schiffelers, L. Jorgensen, Jens Hansen +2 more
2012International journal of pharmaceutics17 citations
Semantic Scholar

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