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F. Viñals · SciRah

Researcher profile · Semantic Scholar

F. Viñals

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F. Viñals — researcher profile on SciRah

h-index: 41
Works: 94
Citations: 7,873

Most-cited papers

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
M. Páez-Ribes, Elizabeth Allen, James Hudock, Takaaki Takeda +6 more
2009Cancer Cell2,445 citations Open access
Semantic Scholar
Recent advances in cancer therapy: an overview.
A. Urruticoechea, R. Alemany, J. Balart, A. Villanueva +2 more
2010Current pharmaceutical design443 citations
Semantic Scholar
p42/p44 MAP Kinase Module Plays a Key Role in the Transcriptional Regulation of the Vascular Endothelial Growth Factor Gene in Fibroblasts*
J. Milanini, F. Viñals, J. Pouysségur, G. Pagès
1998Journal of Biological Chemistry334 citations Open access
Semantic Scholar
Phosphorylated Map Kinase (ERK1, ERK2) Expression is Associated with Early Tau Deposition in Neurones and Glial Cells, but not with Increased Nuclear DNA Vulnerability and Cell Death, in Alzheimer Disease, Pick's Disease, Progressive Supranuclear Palsy and Corticobasal Degeneration
I. Ferrer, R. Blanco, M. Carmona, R. Ribera +6 more
2001Brain Pathology232 citations Open access
Semantic Scholar
Phosphatidylinositol 3-Kinase Inhibitors Block Differentiation of Skeletal Muscle Cells*
P. Kaliman, F. Viñals, X. Testar, M. Palacín +1 more
1996Journal of Biological Chemistry210 citations Open access
Semantic Scholar
Signaling angiogenesis via p42/p44 MAP kinase and hypoxia.
E. Berra, J. Milanini, D. Richard, M. le Gall +5 more
2000Biochemical Pharmacology205 citations
Semantic Scholar
RANK induces epithelial-mesenchymal transition and stemness in human mammary epithelial cells and promotes tumorigenesis and metastasis.
M. Palafox, I. Ferrer, Pasquale Pellegrini, S. Vila +10 more
2012Cancer Research193 citations
Semantic Scholar
A1 Adenosine Receptors Accumulate in Neurodegenerative Structures in Alzheimer's Disease and Mediate Both Amyloid Precursor Protein Processing and Tau Phosphorylation and Translocation
Ester Angulo, V. Casadó, J. Mallol, E. Canela +4 more
2003Brain Pathology187 citations Open access
Semantic Scholar
Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability*
Andrés Méndez-Lucas, P. Hyroššová, L. Novellasdemunt, F. Viñals +1 more
2014Journal of Biological Chemistry174 citations Open access
Semantic Scholar
p70 S6 Kinase-mediated Protein Synthesis Is a Critical Step for Vascular Endothelial Cell Proliferation*
F. Viñals, J. Chambard, J. Pouysségur
1999Journal of Biological Chemistry169 citations Open access
Semantic Scholar
Signaling Angiogenesis via p42/p44 MAP Kinase Cascade
G. Pagès, J. Milanini, D. Richard, E. Berra +3 more
2000Annals of the New York Academy of Sciences140 citations
Semantic Scholar
MPP+ increases α-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells
Cristina Gómez-Santos, I. Ferrer, J. Reiriz, F. Viñals +2 more
2002138 citations
Semantic Scholar
Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP‐2
F. Viñals, Teresa López-Rovira, J. L. Rosa, F. Ventura
2002FEBS Letters135 citations
Semantic Scholar
BMP‐2 decreases Mash1 stability by increasing Id1 expression
F. Viñals, J. Reiriz, S. Ambrosio, R. Bartrons +2 more
2004EMBO Journal117 citations Open access
Semantic Scholar
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect
Paula Lopez-Serra, M. Marcilla, A. Villanueva, A. Ramos-Fernández +24 more
2014Nature Communications115 citations Open access
Semantic Scholar
Confluence of Vascular Endothelial Cells Induces Cell Cycle Exit by Inhibiting p42/p44 Mitogen-Activated Protein Kinase Activity
F. Viñals, J. Pouysségur
1999Molecular and Cellular Biology112 citations Open access
Semantic Scholar
Resistance to Antiangiogenic Therapies by Metabolic Symbiosis in Renal Cell Carcinoma PDX Models and Patients
Gabriela Jiménez-Valerio, M. Martínez-Lozano, Nicklas Bassani, A. Vidal +8 more
2016Cell Reports109 citations Open access
Semantic Scholar
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
Helena Serra, I. Chivite, Ana Angulo-Urarte, Adriana Soler +16 more
2015Nature Communications104 citations Open access
Semantic Scholar
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility
Ana Angulo-Urarte, P. Casado, Sandra D. Castillo, Piotr Kobialka +17 more
2018Nature Communications101 citations Open access
Semantic Scholar
Filamin B Plays a Key Role in Vascular Endothelial Growth Factor-induced Endothelial Cell Motility through Its Interaction with Rac-1 and Vav-2*
B. Del Valle-Pérez, V. Martínez, Cristina Lacasa-Salavert, A. Figueras +6 more
2010Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Lurbinectedin (PM01183), a New DNA Minor Groove Binder, Inhibits Growth of Orthotopic Primary Graft of Cisplatin-Resistant Epithelial Ovarian Cancer
A. Vidal, Clara Muñoz, M. Guillén, J. Moretó +20 more
2012Clinical Cancer Research94 citations Open access
Semantic Scholar
Metronomic chemotherapy following the maximum tolerated dose is an effective anti‐tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells
M. Vives, Mireia M. Ginestà, Kristina Gracova, M. Graupera +5 more
2013International Journal of Cancer88 citations
Semantic Scholar
Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling.
F. Viñals, J. Pouysségur
2001Molecular and Cellular Biology85 citations
Semantic Scholar
CDK-mediated activation of the SCFFBXO28 ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Diana Cepeda, Hwee-Fang Ng, H. Sharifi, S. Mahmoudi +26 more
2013EMBO Molecular Medicine83 citations Open access
Semantic Scholar
Myogenesis and MyoD Down-regulate Sp1
F. Viñals, C. Fandos, T. Santalucía, Josep Ferré +3 more
1997Journal of Biological Chemistry82 citations Open access
Semantic Scholar
ALK1 Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K Activation
Elisenda Alsina-Sanchís, Yaiza García-Ibáñez, Ana M. Figueiredo, Carla Riera-Domingo +8 more
2018Arteriosclerosis, Thrombosis and Vascular Biology77 citations Open access
Semantic Scholar
Antiangiogenic effect of gemcitabine following metronomic administration in a pancreas cancer model
B. Laquente, C. Lacasa, M. Ginestà, O. Casanovas +6 more
2008Molecular Cancer Therapeutics72 citations Open access
Semantic Scholar
Prodigiosin induces the proapoptotic gene NAG-1 via glycogen synthase kinase-3β activity in human breast cancer cells
V. Soto-Cerrato, F. Viñals, J. R. Lambert, J. A. Kelly +1 more
2007Molecular Cancer Therapeutics71 citations
Semantic Scholar
Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat
Isidro Ferrer, R. Blanco, Margarita Carmona, B. Puig +2 more
2002Acta Neuropathologica71 citations
Semantic Scholar
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells.
Cristina Gómez-Santos, I. Ferrer, J. Reiriz, F. Viñals +2 more
2002Brain Research70 citations
Semantic Scholar
Sunitinib Inhibits Tumor Growth and Synergizes with Cisplatin in Orthotopic Models of Cisplatin-Sensitive and Cisplatin-Resistant Human Testicular Germ Cell Tumors
W. Castillo-Ávila, J. Piulats, Xavier García del Muro, A. Vidal +7 more
2009Clinical Cancer Research68 citations Open access
Semantic Scholar
Metronomic chemotherapy: an antiangiogenic scheduling
B. Laquente, F. Viñals, J. Germá
2007Clinical and Translational Oncology67 citations
Semantic Scholar
Molecular mechanisms involved in the adenosine A1 and A2A receptor‐induced neuronal differentiation in neuroblastoma cells and striatal primary cultures
M. Canals, Ester Angulo, V. Casadó, E. Canela +10 more
2005Journal of Neurochemistry67 citations Open access
Semantic Scholar
Factors Involved in GLUT-1 Glucose Transporter Gene Transcription in Cardiac Muscle*
T. Santalucía, K. Boheler, N. Brand, Una Sahye +6 more
1999Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors
Álvaro Lahiguera, P. Hyroššová, A. Figueras, Diana Garzón +21 more
2020EMBO Molecular Medicine61 citations Open access
Semantic Scholar
PI3K (Phosphatidylinositol 3-Kinase) Activation and Endothelial Cell Proliferation in Patients with Hemorrhagic Hereditary Telangiectasia Type 1
A. Iriarte, A. Figueras, P. Cerdà, J. M. Mora +4 more
2019Cells52 citations Open access
Semantic Scholar
The TGFβ pathway stimulates ovarian cancer cell proliferation by increasing IGF1R levels
Elisenda Alsina-Sanchís, A. Figueras, Álvaro Lahiguera, A. Vidal +4 more
2016International Journal of Cancer52 citations Open access
Semantic Scholar
The anticancer agent prodigiosin induces p21WAF1/CIP1 expression via transforming growth factor-beta receptor pathway.
V. Soto-Cerrato, F. Viñals, J. R. Lambert, R. Pérez-Tomás
2007Biochemical Pharmacology50 citations
Semantic Scholar
Myogenin Protein Stability Is Decreased by BMP-2 through a Mechanism Implicating Id1*
F. Viñals, F. Ventura
2004Journal of Biological Chemistry47 citations Open access
Semantic Scholar
A Role for CXCR4 in Peritoneal and Hematogenous Ovarian Cancer Dissemination
A. Figueras, Elisenda Alsina-Sanchís, Álvaro Lahiguera, M. Abreu +8 more
2017Molecular Cancer Therapeutics41 citations
Semantic Scholar
Induction of the Sry-related factor SOX6 contributes to bone morphogenetic protein-2-induced chondroblastic differentiation of C3H10T1/2 cells.
R. Fernández-Lloris, F. Viñals, Teresa López-Rovira, V. Harley +3 more
2003Molecular Endocrinology41 citations Open access
Semantic Scholar
Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2
J. García-Cano, Susana Sánchez-Tena, Joan Sala-Gaston, A. Figueras +4 more
2019Molecular Oncology40 citations Open access
Semantic Scholar
Therapeutic benefit of selective inhibition of p110α PI3-kinase in pancreatic neuroendocrine tumors
Adriana Soler, Ana M. Figueiredo, P. Castel, Laura Martín +7 more
2016Clinical Cancer Research38 citations Open access
Semantic Scholar
Regulation of ubiquitous 6‐phosphofructo‐2‐kinase by the ubiquitin‐proteasome proteolytic pathway during myogenic C2C12 cell differentiation
Lluı́s Riera, M. Obach, Àurea Navarro-Sabaté, Joan Duran +5 more
2003FEBS Letters38 citations
Semantic Scholar
Molecular mechanisms behind the resistance of cisplatin in germ cell tumours
J. M. Piulats, L. Jiménez, Xavier García del Muro, A. Villanueva +2 more
2009Clinical and Translational Oncology36 citations
Semantic Scholar
BMP‐2 regulation of PTHrP and osteoclastogenic factors during osteoblast differentiation of C2C12 cells
Antonio R. G. Susperregui, F. Viñals, P. W. Ho, M. T. Gillespie +2 more
2008Journal of Cellular Physiology36 citations Open access
Semantic Scholar
The impact of KRAS mutations on VEGF-A production and tumour vascular network
A. Figueras, M. Arbós, M. Quiles, F. Viñals +2 more
2013BMC Cancer35 citations Open access
Semantic Scholar
Disruption of GLUT1 glucose carrier trafficking in L6E9 and Sol8 myoblasts by the phosphatidylinositol 3-kinase inhibitor wortmannin.
P. Kaliman, F. Viñals, X. Testar, M. Palacín +1 more
1995Biochemical Journal35 citations Open access
Semantic Scholar
System A transport activity is stimulated in skeletal muscle in response to diabetes
A. Gumà, C. Mora, T. Santalucía, F. Viñals +3 more
1992FEBS Letters32 citations Open access
Semantic Scholar
Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick’s disease
B. Puig, F. Viñals, I. Ferrer
2004Acta Neuropathologica28 citations
Semantic Scholar

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M. Palacín — researcher profile on SciRah

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