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E. Canela · SciRah

Researcher profile · Semantic Scholar

E. Canela

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E. Canela — researcher profile on SciRah

h-index: 64
Works: 218
Citations: 11K

Most-cited papers

Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in Brain*
Lucía Callén, E. Moreno, P. Barroso-Chinea, D. Moreno-Delgado +8 more
2012Journal of Biological Chemistry230 citations Open access
Semantic Scholar
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors
X. Viñals, E. Moreno, L. Lanfumey, A. Cordomí +11 more
2015PLoS Biology188 citations Open access
Semantic Scholar
Binding and Signaling Studies Disclose a Potential Allosteric Site for Cannabidiol in Cannabinoid CB2 Receptors
E. Martínez-Pinilla, K. Varani, Irene Reyes-Resina, Edgar Angelats +9 more
2017Frontiers in Pharmacology186 citations Open access
Semantic Scholar
Direct involvement of σ-1 receptors in the dopamine D1 receptor-mediated effects of cocaine
Gemma Navarro, E. Moreno, Marisol Aymerich, D. Marcellino +10 more
2010Proceedings of the National Academy of Sciences of the United States of America173 citations Open access
Semantic Scholar
Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer
J. Bonaventura, Gemma Navarro, Verònica Casadó-Anguera, Karima Azdad +11 more
2015Proceedings of the National Academy of Sciences of the United States of America162 citations Open access
Semantic Scholar
Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors
C. Ferrada, E. Moreno, V. Casadó, G. Bongers +7 more
2009British Journal of Pharmacology162 citations Open access
Semantic Scholar
Circadian-Related Heteromerization of Adrenergic and Dopamine D4 Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland
Sergio González, D. Moreno-Delgado, E. Moreno, Kamil Pérez‐Capote +9 more
2012PLoS Biology161 citations Open access
Semantic Scholar
Striatal Pre- and Postsynaptic Profile of Adenosine A2A Receptor Antagonists
M. Orrù, J. Bakešová, Marc Brugarolas, César Quiroz +8 more
2011PLoS ONE145 citations Open access
Semantic Scholar
Cocaine Inhibits Dopamine D2 Receptor Signaling via Sigma-1-D2 Receptor Heteromers
Gemma Navarro, E. Moreno, J. Bonaventura, Marc Brugarolas +10 more
2013PLoS ONE142 citations Open access
Semantic Scholar
Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes
G. Navarro, K. Varani, Irene Reyes-Resina, Verónica Sánchez de Medina +9 more
2018Frontiers in Pharmacology141 citations Open access
Semantic Scholar
THEMED ISSUE: CANNABINOIDS REVIEW Adenosine–cannabinoid receptor interactions. Implications for striatal functionbph_723 443..453
S. Ferré, C. Lluis, Zuzana Justinova, César Quiroz +5 more
2010137 citations
Semantic Scholar
Functional Selectivity of Allosteric Interactions within G Protein–Coupled Receptor Oligomers: The Dopamine D1-D3 Receptor Heterotetramer
X. Guitart, G. Navarro, E. Moreno, Hideaki Yano +11 more
2014Molecular Pharmacology123 citations Open access
Semantic Scholar
Dopamine D1-histamine H3 Receptor Heteromers Provide a Selective Link to MAPK Signaling in GABAergic Neurons of the Direct Striatal Pathway*
E. Moreno, Hanne M. Hoffmann, Marta González-Sepúlveda, G. Navarro +11 more
2010Journal of Biological Chemistry122 citations Open access
Semantic Scholar
Receptor-heteromer mediated regulation of endocannabinoid signaling in activated microglia. Role of CB1 and CB2 receptors and relevance for Alzheimer's disease and levodopa-induced dyskinesia.
Gemma Navarro, D. Borroto-Escuela, Edgar Angelats, Íñigo Etayo +10 more
2018Brain, behavior, and immunity118 citations
Semantic Scholar
Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase
Gemma Navarro, A. Cordomí, Verònica Casadó-Anguera, E. Moreno +8 more
2018Nature Communications118 citations Open access
Semantic Scholar
Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer.
E. Pérez‐Gómez, C. Andradas, S. Blasco-Benito, M. Caffarel +28 more
2015Journal of the National Cancer Institute115 citations Open access
Semantic Scholar
The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?
E. Moreno, M. Čavić, A. Krivokuća, V. Casadó +1 more
2019Frontiers in Pharmacology111 citations Open access
Semantic Scholar
Interactions between Intracellular Domains as Key Determinants of the Quaternary Structure and Function of Receptor Heteromers*
Gemma Navarro, S. Ferré, A. Cordomí, E. Moreno +10 more
2010Journal of Biological Chemistry111 citations Open access
Semantic Scholar
Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs
Gemma Navarro, A. Cordomí, M. Zelman-Femiak, Marc Brugarolas +12 more
2016BMC Biology109 citations Open access
Semantic Scholar
Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling*
E. Moreno, C. Andradas, Mireia Medrano, M. Caffarel +11 more
2014Journal of Biological Chemistry104 citations Open access
Semantic Scholar
GPCR homomers and heteromers: A better choice as targets for drug development than GPCR monomers?
V. Casadó, Antonio Cortés, J. Mallol, Kamil Pérez‐Capote +4 more
2009Pharmacology and Therapeutics97 citations Open access
Semantic Scholar
L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus.
J. Bonaventura, A. J. Rico, E. Moreno, S. Sierra +15 more
2014Neuropharmacology89 citations
Semantic Scholar
L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies.
A. Pinna, J. Bonaventura, Daniel Farré, Marta Sánchez +14 more
2014Experimental Neurology85 citations
Semantic Scholar
Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain
Gemma Navarro, A. Cordomí, Marc Brugarolas, E. Moreno +11 more
2018BMC Biology84 citations Open access
Semantic Scholar
Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins
E. Moreno, Júlia Canet, Eduard Gracia, C. Lluis +4 more
2018Frontiers in Pharmacology73 citations Open access
Semantic Scholar
Moonlighting Adenosine Deaminase: A Target Protein for Drug Development
Antonio Cortés, Eduard Gracia, E. Moreno, J. Mallol +3 more
2015Medicinal research reviews (Print)72 citations
Semantic Scholar
Orexin–Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine
Gemma Navarro, César Quiroz, D. Moreno-Delgado, A. Sierakowiak +14 more
2015Journal of Neuroscience72 citations Open access
Semantic Scholar
Molecular and functional interaction between GPR18 and cannabinoid CB2 G‐protein‐coupled receptors. Relevance in neurodegenerative diseases
Irene Reyes-Resina, Gemma Navarro, D. Aguinaga, E. Canela +6 more
2018Biochemical Pharmacology69 citations Open access
Semantic Scholar
Cocaine Disrupts Histamine H3 Receptor Modulation of Dopamine D1 Receptor Signaling: σ1-D1-H3 Receptor Complexes as Key Targets for Reducing Cocaine's Effects
E. Moreno, D. Moreno-Delgado, G. Navarro, Hanne M. Hoffmann +13 more
2014Journal of Neuroscience66 citations Open access
Semantic Scholar
Interactions between Calmodulin, Adenosine A2A, and Dopamine D2 Receptors*
Gemma Navarro, Marisol Aymerich, D. Marcellino, Antonio Cortés +10 more
2009Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Stronger Dopamine D1 Receptor-Mediated Neurotransmission in Dyskinesia
Daniel Farré, A. Muñoz, E. Moreno, Irene Reyes-Resina +12 more
2015Molecular Neurobiology65 citations
Semantic Scholar
Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum
E. Moreno, A. Chiarlone, Mireia Medrano, M. Puigdellívol +19 more
2017Neuropsychopharmacology64 citations Open access
Semantic Scholar
Adenosine A2A Receptors and A2A Receptor Heteromers as Key Players in Striatal Function
S. Ferré, César Quiroz, M. Orrù, X. Guitart +6 more
2011Frontiers in Neuroanatomy59 citations Open access
Semantic Scholar
Therapeutic targeting of HER2–CB2R heteromers in HER2-positive breast cancer
S. Blasco-Benito, E. Moreno, M. Seijo-Vila, I. Tundidor +19 more
2019Proceedings of the National Academy of Sciences of the United States of America57 citations Open access
Semantic Scholar
Potentiation of cannabinoid signaling in microglia by adenosine A2A receptor antagonists
R. Franco, Irene Reyes-Resina, D. Aguinaga, Alejandro Lillo +10 more
2019Glia56 citations
Semantic Scholar
The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors
Eduard Gracia, Daniel Farré, Antonio Cortés, Carles Ferrer-Costa +8 more
2013The FASEB Journal55 citations Open access
Semantic Scholar
Targeting the dopamine D3 receptor: an overview of drug design strategies
Antonio Cortés, E. Moreno, M. Rodríguez-Ruiz, E. Canela +1 more
2016Expert Opinion on Drug Discovery54 citations
Semantic Scholar
G Protein-Coupled Receptor Heteromers as New Targets for Drug Development
S. Ferré, Gemma Navarro, V. Casadó, Antonio Cortés +4 more
2010Progress in Molecular Biology and Translational Science52 citations Open access
Semantic Scholar
Heteroreceptor Complexes Formed by Dopamine D1, Histamine H3, and N-Methyl-D-Aspartate Glutamate Receptors as Targets to Prevent Neuronal Death in Alzheimer’s Disease
M. Rodríguez-Ruiz, E. Moreno, D. Moreno-Delgado, Gemma Navarro +7 more
2017Molecular Neurobiology51 citations Open access
Semantic Scholar
Intracellular Calcium Levels Determine Differential Modulations of Allosteric Interactions within G Protein-Coupled Receptor Heteromers
G. Navarro, D. Aguinaga, E. Moreno, Johannes Hradsky +10 more
2014Chemistry and Biology51 citations Open access
Semantic Scholar
A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase.
Eduard Gracia, Kamil Pérez‐Capote, E. Moreno, Jana Barkešová +6 more
2011Biochemical Journal48 citations Open access
Semantic Scholar
Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.
V. Casadó, C. Ferrada, J. Bonaventura, Eduard Gracia +5 more
2009Biochemical Pharmacology46 citations Open access
Semantic Scholar
Adenosine A1-Dopamine D1 Receptor Heteromers Control the Excitability of the Spinal Motoneuron
Marla Rivera-Oliver, E. Moreno, Yocasta Alvarez-Bagnarol, Christian Ayala-Santiago +7 more
2018Molecular Neurobiology45 citations Open access
Semantic Scholar
A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons*
Gemma Navarro, D. Aguinaga, Edgar Angelats, Mireia Medrano +8 more
2016Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells
L. Galindo, E. Moreno, Fernando López-Armenta, D. Guinart +12 more
2018Molecular Neurobiology40 citations Open access
Semantic Scholar
Dopamine-galanin receptor heteromers modulate cholinergic neurotransmission in the rat ventral hippocampus
E. Moreno, S. Vaz, N. Cai, C. Ferrada +10 more
2011Journal of Neuroscience38 citations Open access
Semantic Scholar
Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area
E. Moreno, César Quiroz, W. Rea, N. Cai +6 more
2017Journal of Neuroscience36 citations Open access
Semantic Scholar
Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens
X. Guitart, E. Moreno, W. Rea, Marta Sánchez-Soto +10 more
2019Molecular Neurobiology33 citations Open access
Semantic Scholar
Cannabinoid receptors CB 1 and CB 2 form functional heteromers in the brain #
Lucía Callén, E. Moreno, P. Barroso-Chinea, D. Moreno-Delgado +8 more
201232 citations
Semantic Scholar
The Interplay between Cancer Biology and the Endocannabinoid System—Significance for Cancer Risk, Prognosis and Response to Treatment
E. Moreno, M. Čavić, A. Krivokuća, E. Canela
2020Cancers30 citations Open access
Semantic Scholar

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V. Casadó×39
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V. Casadó — researcher profile on SciRah
C. Lluis×37
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C. Lluis — researcher profile on SciRah
E. Moreno×36
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E. Moreno — researcher profile on SciRah
Antonio Cortés×34
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Antonio Cortés — researcher profile on SciRah

×29

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J. Mallol — researcher profile on SciRah

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R. Franco — researcher profile on SciRah

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S. Ferré — researcher profile on SciRah

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P. McCormick — researcher profile on SciRah

Gemma Navarro×20

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Gemma Navarro — researcher profile on SciRah

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J. Lanciego — researcher profile on SciRah

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D. Aguinaga — researcher profile on SciRah

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César Quiroz — researcher profile on SciRah