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B. Puig · SciRah

Researcher profile · Semantic Scholar

B. Puig

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B. Puig — researcher profile on SciRah

h-index: 36
Works: 86
Citations: 4,522

Most-cited papers

Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies.
I. Ferrer, T. Gómez-Isla, B. Puig, M. Freixes +3 more
2005Current Alzheimer Research314 citations
Semantic Scholar
Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex
V. Martín, Noemí Fabelo, G. Santpere, B. Puig +3 more
2010Journal of Alzheimer's Disease266 citations Open access
Semantic Scholar
Phosphorylated Map Kinase (ERK1, ERK2) Expression is Associated with Early Tau Deposition in Neurones and Glial Cells, but not with Increased Nuclear DNA Vulnerability and Cell Death, in Alzheimer Disease, Pick's Disease, Progressive Supranuclear Palsy and Corticobasal Degeneration
I. Ferrer, R. Blanco, M. Carmona, R. Ribera +6 more
2001Brain Pathology232 citations Open access
Semantic Scholar
Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in neurons and glial cells in tauopathies
I. Ferrer, R. Blanco, M. Carmona, B. Puig
2001Journal of neural transmission203 citations
Semantic Scholar
Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
I. Ferrer, M. Barrachina, B. Puig
2002Acta Neuropathologica196 citations
Semantic Scholar
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.
Elena M. Ribé, Mar Pérez, B. Puig, I. Gich +15 more
2005Neurobiology of Disease176 citations Open access
Semantic Scholar
Brain Protein Preservation Largely Depends on the Postmortem Storage Temperature: Implications for Study of Proteins in Human Neurologic Diseases and Management of Brain Banks: A BrainNet Europe Study
I. Ferrer, G. Santpere, T. Arzberger, J. Bell +12 more
2007Journal of Neuropathology and Experimental Neurology173 citations Open access
Semantic Scholar
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.
I. Ferrer, M. Barrachina, B. Puig, M. M. de Lagrán +3 more
2005Neurobiology of Disease169 citations Open access
Semantic Scholar
Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies
I. Ferrer, R. Blanco, M. Carmona, B. Puig +3 more
2001Journal of neural transmission161 citations
Semantic Scholar
CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression
Enja Schneider, Riekje Winzer, A. Rissiek, Isabell Ricklefs +16 more
2021Nature Communications132 citations Open access
Semantic Scholar
Molecular Communication of a Dying Neuron in Stroke
B. Puig, S. Brenna, T. Magnus
2018International Journal of Molecular Sciences131 citations Open access
Semantic Scholar
Lack of a-disintegrin-and-metalloproteinase ADAM10 leads to intracellular accumulation and loss of shedding of the cellular prion protein in vivo
H. Altmeppen, Johannes Prox, B. Puig, M. Kluth +8 more
2011Molecular Neurodegeneration113 citations Open access
Semantic Scholar
Prion protein expression in senile plaques in Alzheimer's disease
I. Ferrer, R. Blanco, M. Carmona, B. Puig +3 more
2000Acta Neuropathologica104 citations
Semantic Scholar
VDAC and ERalpha interaction in caveolae from human cortex is altered in Alzheimer's disease.
C. Ramírez, Miriam González, M. Díaz, R. Alonso +5 more
2009Molecular and cellular neurosciences97 citations
Semantic Scholar
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
S. Brenna, H. Altmeppen, B. Mohammadi, B. Rissiek +9 more
2020Journal of Extracellular Vesicles96 citations Open access
Semantic Scholar
Proteolytic processing of the prion protein in health and disease.
H. Altmeppen, B. Puig, F. Dohler, Dana Thurm +3 more
2012American Journal of Neurodegenerative Disease96 citations
Semantic Scholar
Expression of stress‐activated kinases c‐Jun N‐terminal kinase (SAPK/JNK‐P) and p38 kinase (p38‐P), and tau hyperphosphorylation in neurites surrounding βA plaques in APP Tg2576 mice
B. Puig, Teresa Gomez-Isla, Elena M. Ribé, M. Cuadrado +3 more
2004Neuropathology and Applied Neurobiology94 citations
Semantic Scholar
Multiple cervical artery dissections
J. Zarranz, Isidro Ferrer, E. Lezcano, M. I. Forcadas +13 more
2005Neurology90 citations Open access
Semantic Scholar
The sheddase ADAM10 is a potent modulator of prion disease
H. Altmeppen, Johannes Prox, S. Krasemann, B. Puig +10 more
2015eLife83 citations Open access
Semantic Scholar
Deposition of Hyperphosphorylated Tau in Cerebellum of PS1 E280A Alzheimer's Disease
D. Sepulveda-Falla, J. Matschke, C. Bernreuther, C. Hagel +8 more
2011Brain Pathology81 citations Open access
Semantic Scholar
Abnormal Sp1 transcription factor expression in Alzheimer disease and tauopathies.
G. Santpere, M. Nieto, B. Puig, I. Ferrer
2006Neuroscience Letters72 citations
Semantic Scholar
Active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates are differentially expressed following systemic administration of kainic acid to the adult rat
Isidro Ferrer, R. Blanco, Margarita Carmona, B. Puig +2 more
2002Acta Neuropathologica71 citations
Semantic Scholar
Prion protein deposition and abnormal synaptic protein expression in the cerebellum in Creutzfeldt-Jakob disease.
Isidro Ferrer, B. Puig, R. Blanco, E. Martí
2000Neuroscience71 citations
Semantic Scholar
Phosphorylated Protein Kinases Associated with Neuronal and Glial Tau Deposits in Argyrophilic Grain Disease
Isidro Ferrer, M. Barrachina, Markus Tolnay, M. Rey +4 more
2003Brain Pathology65 citations Open access
Semantic Scholar
Primary progressive aphasia as the initial manifestation of corticobasal degeneration and unusual tauopathies
I. Ferrer, I. Hernández, M. Boada, A. Llorente +4 more
2003Acta Neuropathologica65 citations
Semantic Scholar
Generation and Function of Non-cell-bound CD73 in Inflammation
Enja Schneider, A. Rissiek, Riekje Winzer, B. Puig +5 more
2019Frontiers in Immunology60 citations Open access
Semantic Scholar
Clusterin solubility and aggregation in Creutzfeldt-Jakob disease
M. Freixes, B. Puig, Agustín Rodríguez, Benjamín Torrejón-Escribano +2 more
2004Acta Neuropathologica54 citations
Semantic Scholar
A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer’s disease
D. Sepulveda-Falla, L. Chávez-Gutiérrez, E. Portelius, J. I. Velez +12 more
2020Acta Neuropathologica52 citations Open access
Semantic Scholar
The GPI-anchoring of PrP
B. Puig, H. Altmeppen, M. Glatzel
2014Prion52 citations Open access
Semantic Scholar
Roles of endoproteolytic α‐cleavage and shedding of the prion protein in neurodegeneration
Hermann C. Altmeppen, Johannes Prox, B. Puig, F. Dohler +3 more
2013The FEBS Journal52 citations Open access
Semantic Scholar
Phosphorylated c‐MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration
Isidro Ferrer, R. Blanco, Margarita Carmona, B. Puig
2001Neuropathology and Applied Neurobiology52 citations
Semantic Scholar
Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat.
B. Puig, Isidro Ferrer
2002Neuroscience Letters50 citations
Semantic Scholar
Fas and Fas ligand expression in Alzheimer's disease
Isidro Ferrer, B. Puig, Jerzy Krupinski, Margarita Carmona +1 more
2001Acta Neuropathologica49 citations
Semantic Scholar
Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein
Luise Linsenmeier, B. Mohammadi, S. Wetzel, B. Puig +9 more
2018Molecular Neurodegeneration45 citations Open access
Semantic Scholar
GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice
B. Puig, H. Altmeppen, Luise Linsenmeier, Karima Chakroun +6 more
2019PLoS Pathogens38 citations Open access
Semantic Scholar
Cell death signaling in the cerebellum in Creutzfeldt-Jakob disease
B. Puig, Isidro Ferrer
2001Acta Neuropathologica37 citations
Semantic Scholar
Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains
Isidro Ferrer, M. Barrachina, B. Puig
2002Acta Neuropathologica35 citations
Semantic Scholar
Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective
S. Brenna, C. Krisp, H. Altmeppen, T. Magnus +1 more
2021International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
Cleaved caspase-3, caspase-7 and poly (ADP-ribose) polymerase are complementarily but differentially expressed in human medulloblastomas.
B. Puig, A. Tortosa, Isidro Ferrer
2001Neuroscience Letters32 citations
Semantic Scholar
Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice
B. Puig, H. Altmeppen, S. Ulbrich, Luise Linsenmeier +6 more
2016Scientific Reports31 citations Open access
Semantic Scholar
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies
Luise Linsenmeier, B. Mohammadi, M. Shafiq, K. Frontzek +30 more
2021Science Advances28 citations Open access
Semantic Scholar
Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick’s disease
B. Puig, F. Viñals, I. Ferrer
2004Acta Neuropathologica28 citations
Semantic Scholar
Release of VAMP5‐positive extracellular vesicles by retinal Müller glia in vivo
V. Demais, Anne Pohl, K. Wunderlich, Anna M. Pfaller +8 more
2022bioRxiv25 citations Open access
Semantic Scholar
N-Glycans and Glycosylphosphatidylinositol-Anchor Act on Polarized Sorting of Mouse PrPC in Madin-Darby Canine Kidney Cells
B. Puig, H. Altmeppen, Dana Thurm, M. Geissen +3 more
2011PLoS ONE25 citations Open access
Semantic Scholar
Amyloid-β deposition in the cerebral cortex in Dementia with Lewy bodies is accompanied by a relative increase in AβPP mRNA isoforms containing the Kunitz protease inhibitor
M. Barrachina, E. Dalfo, B. Puig, N. Vidal +3 more
200524 citations
Semantic Scholar
GluR2/3, NMDAε1 and GABAA receptors in Creutzfeldt-Jakob disease
Isidro Ferrer, B. Puig
2003Acta Neuropathologica24 citations
Semantic Scholar
Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease
M. Shafiq, Saima Zafar, Neelam Younas, Aneeqa Noor +7 more
2021Molecular Neurodegeneration22 citations Open access
Semantic Scholar
Low molecular weight species of tau in Alzheimer's disease are dependent on tau phosphorylation sites but not on delayed post-mortem delay in tissue processing.
G. Santpere, B. Puig, I. Ferrer
2006Neuroscience Letters22 citations
Semantic Scholar
Metabotropic glutamate receptor/phospholipase C pathway: a vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex.
Agustín Rodríguez, M. Freixes, E. Dalfo, Mairena Martín +2 more
2005Neuroscience21 citations
Semantic Scholar
Ubiquitin-negative mini-pick-like bodies in the dentate gyrus in p301l tauopathy
I. Ferrer, I. Hernández, B. Puig, María Jesús Rey +3 more
2004Journal of Alzheimer's Disease21 citations Open access
Semantic Scholar

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