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K. Wucherpfennig · SciRah

Researcher profile · Semantic Scholar

K. Wucherpfennig

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K. Wucherpfennig — researcher profile on SciRah

h-index: 97
Works: 316
Citations: 39K

Most-cited papers

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
Peng Jiang, Sheng-Qing Gu, D. Pan, Jing-Xin Fu +11 more
2018Nature Medicine4,429 citations Open access
Semantic Scholar
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
D. Keskin, Annabelle J Anandappa, Jing Sun, I. Tirosh +47 more
2018Nature1,268 citations Open access
Semantic Scholar
Radiotherapy induces responses of lung cancer to CTLA-4 blockade
S. Formenti, N. Rudqvist, E. Golden, B. Cooper +14 more
2018Nature Medicine818 citations Open access
Semantic Scholar
A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing
D. Pan, A. Kobayashi, Peng Jiang, L. D. de Andrade +12 more
2018Science764 citations Open access
Semantic Scholar
A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
Livnat Jerby-Arnon, P. Shah, Michael S. Cuoco, C. Rodman +48 more
2018Cell763 citations Open access
Semantic Scholar
MHC-II neoantigens shape tumor immunity and response to immunotherapy
Elise Alspach, D. Lussier, Alexander P. Miceli, Ilya Kizhvatov +19 more
2019Nature756 citations Open access
Semantic Scholar
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
M. Filbin, I. Tirosh, V. Hovestadt, McKenzie L Shaw +45 more
2018Science595 citations Open access
Semantic Scholar
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma
T. Hara, Rony Chanoch-Myers, N. Mathewson, Chad Myskiw +17 more
2021Cancer Cell506 citations Open access
Semantic Scholar
Personal Neoantigen Vaccines Induce Persistent Memory T Cell Responses and Epitope Spreading in Patients with Melanoma
Zhuting Hu, Donna E. Leet, R. Allesøe, G. Oliveira +37 more
2021Nature Medicine493 citations Open access
Semantic Scholar
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell–driven tumor immunity
Lucas Ferrari de Andrade, Rong-En Tay, D. Pan, Adrienne M. Luoma +13 more
2018Science420 citations Open access
Semantic Scholar
Inhibitory CD161 Receptor Identified in Glioma-infiltrating T cells by Single Cell Analysis
N. Mathewson, O. Ashenberg, I. Tirosh, S. Gritsch +36 more
2021Cell377 citations Open access
Semantic Scholar
Tissue-resident Memory and Circulating T cells are Early Responders to Pre-surgical Cancer Immunotherapy
Adrienne M. Luoma, Sheng-Bao Suo, Yi-Fan Wang, L. Gunasti +19 more
2022Cell360 citations Open access
Semantic Scholar
A facile approach to enhance antigen response for personalized cancer vaccination
Aileen W. Li, Miguel C. Sobral, Soumya Badrinath, Youngjin Choi +9 more
2018Nature Materials347 citations Open access
Semantic Scholar
Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma: A Phase 2 Open-Label Randomized Clinical Trial.
J. Schoenfeld, G. Hanna, V. Jo, B. Rawal +22 more
2020JAMA Oncology335 citations Open access
Semantic Scholar
Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient
Neil McCarthy, E. Manieri, E. Storm, A. Saadatpour +11 more
2020Cell Stem Cell311 citations Open access
Semantic Scholar
Quiescent cancer cells resist T cell attack by forming an immunosuppressive niche
P. Baldominos, Alex Barbera-Mourelle, O. Barreiro, Yu Huang +23 more
2022Cell273 citations Open access
Semantic Scholar
Understanding and Treating the Inflammatory Adverse Events of Cancer Immunotherapy
M. Dougan, Adrienne M. Luoma, S. Dougan, K. Wucherpfennig
2021Cell273 citations Open access
Semantic Scholar
Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function
G. Notarangelo, J. Spinelli, Elizabeth M. Perez, G. Baker +20 more
2022Science250 citations Open access
Semantic Scholar
Clinical trial links oncolytic immunoactivation to survival in glioblastoma
Alexander L. Ling, Isaac H. Solomon, Ana Montalvo Landivar, Hiroshi Nakashima +57 more
2023Nature249 citations Open access
Semantic Scholar
Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion
Chris J. Frangieh, Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger-Schuller +18 more
2021Nature Genetics242 citations Open access
Semantic Scholar
T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes
T. Kula, M. Dezfulian, Charlotte I. Wang, Nouran S. Abdelfattah +4 more
2019Cell232 citations Open access
Semantic Scholar
Ascl2-dependent cell dedifferentiation drives regeneration of ablated intestinal stem cells
Kazutaka Murata, U. Jadhav, Shariq Madha, J. V. van Es +6 more
2020Cell Stem Cell222 citations Open access
Semantic Scholar
Systematic Investigation of Cytokine Signaling Activity at the Tissue and Single-Cell Level
Peng Jiang, Yu Zhang, B. Ru, Yuan Yang +8 more
2021Nature Methods211 citations Open access
Semantic Scholar
Designing Cancer Immunotherapies That Engage T Cells and NK Cells
O. Kyrysyuk, K. Wucherpfennig
2022Annual Review of Immunology209 citations Open access
Semantic Scholar
Integrin αvβ6 – TGFβ – SOX4 Pathway Drives Immune Evasion in Triple-negative Breast Cancer
A. Bagati, Sushil Kumar, Peng Jiang, Jason W Pyrdol +12 more
2020Cancer Cell199 citations Open access
Semantic Scholar
Augmenting NK Cell-Based Immunotherapy by Targeting Mitochondrial Apoptosis
Rongqing Pan, J. Ryan, D. Pan, K. Wucherpfennig +1 more
2022Cell184 citations Open access
Semantic Scholar
FAP delineates heterogeneous and functionally divergent stromal cells in immune-excluded breast tumors
V. Cremasco, Jillian L. Astarita, Angelo L Grauel, Shilpa Keerthivasan +16 more
2018Cancer immunology research166 citations Open access
Semantic Scholar
Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer
Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid +35 more
2020Molecules and Cells163 citations Open access
Semantic Scholar
MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets
X. Qiu, N. Boufaied, Tarek Hallal, Avery Feit +31 more
2021Nature Communications145 citations Open access
Semantic Scholar
Metabolic labeling and targeted modulation of dendritic cells
Hua Wang, Miguel C. Sobral, David K. Y. Zhang, Adam N. Cartwright +6 more
2020Nature Materials142 citations Open access
Semantic Scholar
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
M. Janiszewska, D. Tabassum, Z. Castaño, Simona Cristea +20 more
2019Nature Cell Biology140 citations Open access
Semantic Scholar
Landscape of B cell immunity and related immune evasion in human cancers
Xi-Hao Hu, Jian Zhang, Jin Wang, Jing-Xin Fu +16 more
2019Nature Genetics137 citations Open access
Semantic Scholar
A vaccine targeting resistant tumours by dual T cell plus NK cell attack
Soumya Badrinath, Maxence O. Dellacherie, Aileen W. Li, Shi-Wei Zheng +13 more
2022Nature136 citations Open access
Semantic Scholar
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
J. Gojo, B. Englinger, Li Jiang, Jens-Martin Hübner +37 more
2020Cancer Cell135 citations Open access
Semantic Scholar
Discovery of specialized NK cell populations infiltrating human melanoma metastases.
L. D. de Andrade, Yu-Heng Lu, Adrienne M. Luoma, Yoshinaga Ito +5 more
2019JCI Insight122 citations Open access
Semantic Scholar
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Livnat Jerby-Arnon, C. Neftel, M. Shore, Hannah R. Weisman +46 more
2021Nature Medicine120 citations Open access
Semantic Scholar
Inhibition of CDK4/6 promotes CD8 T cell memory formation
Max Heckler, Lestat R. Ali, E. Clancy-Thompson, Li Qiang +20 more
2021Cancer Discovery109 citations Open access
Semantic Scholar
Engineered MBP-specific human Tregs ameliorate MOG-induced EAE through IL-2-triggered inhibition of effector T cells
Y. Kim, Ai-Hong Zhang, Jeongheon Yoon, William E. Culp +3 more
2018Journal of Autoimmunity106 citations Open access
Semantic Scholar
Inhibition of MICA and MICB Shedding Elicits NK cell–mediated Immunity against Tumors Resistant to Cytotoxic T cells
L. D. de Andrade, Sushil Kumar, Adrienne M. Luoma, Yoshinaga Ito +5 more
2020Cancer immunology research104 citations Open access
Semantic Scholar
Mechanical checkpoint regulates monocyte differentiation in fibrotic niches
K. Vining, A. Marneth, Kwasi Adu-Berchie, Joshua M. Grolman +11 more
2022Nature Materials84 citations Open access
Semantic Scholar
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
Jennifer Y. Ge, Shaokun Shu, Mijung Kwon, B. Jovanovic +17 more
2020Nature Communications81 citations Open access
Semantic Scholar
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
P. Ho, Johannes C. Melms, Meri Rogava, Chris J. Frangieh +29 more
2023Cancer Cell78 citations Open access
Semantic Scholar
Mechanism of EBV inducing anti-tumour immunity and its therapeutic use
I. Choi, Zhe Wang, Q. Ke, Min Hong +11 more
2020Nature77 citations Open access
Semantic Scholar
CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor cells and T cells
Sushil Kumar, Ze-Xian Zeng, A. Bagati, Rong-En Tay +18 more
2021Cancer Discovery76 citations Open access
Semantic Scholar
Replicational Dilution of H3K27me3 in Mammalian Cells and the Role of Poised Promoters
U. Jadhav, E. Manieri, Kodandaramireddy Nalapareddy, Shariq Madha +4 more
2020Molecules and Cells66 citations Open access
Semantic Scholar
Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma
P. Ott, Zhuting Hu, D. Keskin, S. Shukla +36 more
2018Nature65 citations Open access
Semantic Scholar
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
J. Grootjans, N. Krupka, S. Hosomi, J. D. Matute +27 more
2019Science60 citations Open access
Semantic Scholar
Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
Rong-En Tay, Olamide Olawoyin, P. Cejas, Ying-Tian Xie +8 more
2020Journal of Experimental Medicine57 citations Open access
Semantic Scholar
Cytokine conjugation to enhance T cell therapy
Yutong Liu, Kwasi Adu-Berchie, Joshua M. Brockman, Matthew J. Pezone +6 more
2022Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
cIAP1/2 antagonism eliminates MHC class I negative tumors through T cell-dependent reprogramming of mononuclear phagocytes
Kevin Roehle, Li Qiang, Katherine S. Ventre, D. Heid +25 more
2021Science Translational Medicine50 citations Open access
Semantic Scholar

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