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A. Leutz · SciRah

Researcher profile · Semantic Scholar

A. Leutz

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A. Leutz — researcher profile on SciRah

h-index: 51
Works: 150
Citations: 10K

Most-cited papers

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
Ann-Marie E. Bröske, Lena Vockentanz, S. Kharazi, Matthew R. Huska +11 more
2009Nature Genetics496 citations
Semantic Scholar
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
H. Bourbon, A. Aguilera, A. Ansari, F. Asturias +43 more
2004Molecules and Cells291 citations Open access
Semantic Scholar
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells.
Bérengère de Laval, Julien Maurizio, P. Kandalla, G. Brisou +13 more
2020Cell Stem Cell279 citations Open access
Semantic Scholar
Genomic Characterization of Murine Monocytes Reveals C/EBP&bgr; Transcription Factor Dependence of Ly6C− Cells
A. Mildner, Jörg Schönheit, A. Giladi, Eyal David +8 more
2017Immunity268 citations Open access
Semantic Scholar
Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth
D. Simmons, D. Natale, V. Bégay, M. Hughes +2 more
2008Development257 citations Open access
Semantic Scholar
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
F. Rosenbauer, B. Owens, Li Yu, Joseph R. Tumang +13 more
2006Nature Genetics255 citations
Semantic Scholar
Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
M. Scheller, J. Huelsken, F. Rosenbauer, M. Taketo +3 more
2006Nature Immunology246 citations Open access
Semantic Scholar
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.
Grégoire Jeannet, M. Scheller, L. Scarpellino, S. Duboux +8 more
2008Blood240 citations Open access
Semantic Scholar
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
M. Scheller, J. Huelsken, F. Rosenbauer, M. Taketo +3 more
2006Nature Immunology219 citations
Semantic Scholar
Ras induces mediator complex exchange on C/EBP beta.
Xian-Ming Mo, E. Kowenz-Leutz, Hong Xu, A. Leutz
2004Molecules and Cells194 citations Open access
Semantic Scholar
Upstream open reading frames: Molecular switches in (patho)physiology
K. Wethmar, J. J. Smink, A. Leutz
2010Bioessays191 citations Open access
Semantic Scholar
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas.
F. Jundt, Nina Raetzel, Christine Müller, C. Calkhoven +5 more
2005Blood147 citations
Semantic Scholar
Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB
J. J. Smink, V. Bégay, T. Schoenmaker, E. Sterneck +2 more
2009EMBO Journal143 citations Open access
Semantic Scholar
PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.
Jörg Schönheit, Christiane Kuhl, M. L. Gebhardt, Francisco Fernández Klett +9 more
2013Cell Reports122 citations Open access
Semantic Scholar
SIRT1 regulates macrophage self‐renewal
F. Imperatore, Julien Maurizio, Stephanie Vargas-Aguilar, C. Busch +8 more
2017EMBO Journal121 citations Open access
Semantic Scholar
Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation
A. Giladi, L. K. Wagner, Han-Jie Li, Dorothea Dörr +9 more
2020Nature Immunology109 citations
Semantic Scholar
Crosstalk between C/EBPβ phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
E. Kowenz-Leutz, O. Pless, G. Dittmar, M. Knoblich +1 more
2010EMBO Journal107 citations Open access
Semantic Scholar
G9a-mediated Lysine Methylation Alters the Function of CCAAT/Enhancer-binding Protein-β*
O. Pless, E. Kowenz-Leutz, M. Knoblich, J. Lausen +3 more
2008Journal of Biological Chemistry105 citations Open access
Semantic Scholar
C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals.
K. Wethmar, V. Bégay, J. J. Smink, K. Zaragoza +4 more
2010Genes & Development101 citations Open access
Semantic Scholar
The CCAAT Enhancer-binding Protein α (C/EBPα) Requires a SWI/SNF Complex for Proliferation Arrest*
Christine Müller, C. Calkhoven, Xiaojin Sha, A. Leutz
2004Journal of Biological Chemistry98 citations Open access
Semantic Scholar
uORFdb—a comprehensive literature database on eukaryotic uORF biology
K. Wethmar, A. Barbosa-Silva, Miguel Andrade, A. Leutz
2013Nucleic Acids Res.81 citations Open access
Semantic Scholar
Essential Requirement of CCAAT/Enhancer Binding Proteins in Embryogenesis
V. Bégay, J. J. Smink, A. Leutz
2004Molecular and Cellular Biology81 citations Open access
Semantic Scholar
Translational control of SCL-isoform expression in hematopoietic lineage choice.
C. Calkhoven, C. Muller, R. Martin, Goradz Krosl +3 more
2003Genes & Development80 citations Open access
Semantic Scholar
Histone H3 tail positioning and acetylation by the c-Myb but not the v-Myb DNA-binding SANT domain.
Xian-Ming Mo, E. Kowenz-Leutz, Y. Laumonnier, Hong Xu +1 more
2005Genes & Development73 citations Open access
Semantic Scholar
Loss-of-function uORF mutations in human malignancies
J. Schulz, N. Mah, M. Neuenschwander, Tabea G. Kischka +13 more
2018Scientific Reports57 citations Open access
Semantic Scholar
Long-term, multilineage hematopoiesis occurs in the combined absence of -catenin and -catenin
Grégoire Jeannet, M. Scheller, L. Scarpellino, S. Duboux +8 more
200755 citations
Semantic Scholar
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells.
Bérengère de Laval, Julien Maurizio, P. Kandalla, G. Brisou +13 more
2020Cell Stem Cell52 citations Open access
Semantic Scholar
The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest.
Christine Müller, C. Calkhoven, Xiaojin Sha, A. Leutz
2004Journal of Biological Chemistry48 citations
Semantic Scholar
C/EBP-Induced Transdifferentiation Reveals Granulocyte-Macrophage Precursor-like Plasticity of B Cells
B. Cirovic, Jörg Schönheit, E. Kowenz-Leutz, Jeļena Ivanovska +4 more
2017Stem Cell Reports47 citations Open access
Semantic Scholar
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model
R. Schwarzer, N. Nickel, Julia Godau, B. Willie +7 more
2014Blood Cancer Journal47 citations Open access
Semantic Scholar
Cross talk between Wnt/β-catenin and Irf8 in leukemia progression and drug resistance
M. Scheller, Jörg Schönheit, Karin Zimmermann, U. Leser +2 more
2013Journal of Experimental Medicine46 citations Open access
Semantic Scholar
C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages
Dorothea Dörr, B. Obermayer, J. Weiner, Karin Zimmermann +12 more
2022Science immunology43 citations
Semantic Scholar
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC‐STAMP
Nadine Courtial, J. J. Smink, Olga N. Kuvardina, A. Leutz +2 more
2012The FASEB Journal43 citations
Semantic Scholar
Rapamycin and the transcription factor C/EBPβ as a switch in osteoclast differentiation: implications for lytic bone diseases
J. J. Smink, A. Leutz
2009Journal of molecular medicine43 citations Open access
Semantic Scholar
Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice
Laura M. Zidek, T. Ackermann, Götz Hartleben, Sabrina Eichwald +8 more
2015EMBO Reports41 citations Open access
Semantic Scholar
Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis
V. Bégay, J. J. Smink, C. Loddenkemper, Karin Zimmermann +7 more
2014Journal of molecular medicine38 citations Open access
Semantic Scholar
PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ
G. Dittmar, Daniel Perez Hernandez, E. Kowenz-Leutz, Marieluise Kirchner +9 more
2019iScience37 citations Open access
Semantic Scholar
Repression of Transcriptional Activity of C/EBPα by E2F-Dimerization Partner Complexes
K. Zaragoza, V. Bégay, A. Schuetz, U. Heinemann +1 more
2010Molecular and Cellular Biology37 citations Open access
Semantic Scholar
C/EBPβ regulates homeostatic and oncogenic gastric cell proliferation
G. Regalo, Susann Förster, C. Resende, Bianca Bauer +6 more
2016Journal of molecular medicine36 citations Open access
Semantic Scholar
Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs
A. Leutz, O. Pless, M. Lappe, G. Dittmar +1 more
2011Transcription36 citations Open access
Semantic Scholar
Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis
J. J. Smink, P. Tunn, A. Leutz
2011Journal of molecular medicine33 citations
Semantic Scholar
Comprehensive translational control of tyrosine kinase expression by upstream open reading frames
K. Wethmar, J. Schulz, E. M. Muro, S. Talyan +2 more
2015Oncogene32 citations Open access
Semantic Scholar
Instruction of mesenchymal cell fate by the transcription factor C/EBPβ.
J. J. Smink, A. Leutz
2012Gene32 citations
Semantic Scholar
Lymphoid to Myeloid Cell Trans-Differentiation Is Determined by C/EBPβ Structure and Post-Translational Modifications
B. Stoilova, E. Kowenz-Leutz, M. Scheller, A. Leutz
2013PLoS ONE28 citations Open access
Semantic Scholar
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis
A. Rousselle, Janis Sonnemann, K. Amann, A. Mildner +8 more
2022Annals of the Rheumatic Diseases27 citations Open access
Semantic Scholar
The transcription factor C/EBPβ orchestrates dendritic cell maturation and functionality under homeostatic and malignant conditions
Florian Scholz, M. Grau, Lutz Menzel, Annika Graband +6 more
2020Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
Deficiency in mTORC 1-controlled C / EBP beta-mRNA translation improves metabolic health in mice
Laura M. Zidek, T. Ackermann, Götz Hartleben, Sabrina Eichwald +8 more
201522 citations
Semantic Scholar
The C/EBPβ LIP isoform rescues loss of C/EBPβ function in the mouse
V. Bégay, C. Baumeier, Karin Zimmermann, A. Heuser +1 more
2018Scientific Reports21 citations Open access
Semantic Scholar
C/EBP b D uORF mice—a genetic model for uORF-mediated translational control in mammals
K. Wethmar, V. Bégay, J. J. Smink, K. Zaragoza +4 more
200921 citations
Semantic Scholar
Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia
G. Regalo, A. Leutz
2013EMBO Molecular Medicine20 citations Open access
Semantic Scholar

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