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A. Pandyra · SciRah

Researcher profile · Semantic Scholar

A. Pandyra

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A. Pandyra — researcher profile on SciRah

h-index: 24
Works: 91
Citations: 2,200

Most-cited papers

Dysregulation of the mevalonate pathway promotes transformation
James W. Clendening, A. Pandyra, P. Boutros, Samah El Ghamrasni +7 more
2010Proceedings of the National Academy of Sciences of the United States of America406 citations Open access
Semantic Scholar
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.
Hai-Feng C. Xu, M. Grusdat, A. Pandyra, Robin Polz +15 more
2014Immunity223 citations Open access
Semantic Scholar
Conjugated Bilirubin Triggers Anemia by Inducing Erythrocyte Death
Elisabeth Lang, S. Gatidis, N. Freise, Hans H. Bock +20 more
2014Hepatology115 citations Open access
Semantic Scholar
Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma.
James W. Clendening, A. Pandyra, Zhi-Hua Li, P. Boutros +5 more
2010Blood102 citations
Semantic Scholar
An intact gut microbiome protects genetically predisposed mice against leukemia.
Carolina Vicente-Dueñas, S. Janssen, M. Oldenburg, F. Auer +19 more
2020Blood96 citations Open access
Semantic Scholar
Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop.
A. Pandyra, P. Mullen, M. Kalkat, Rosemary Yu +7 more
2014Cancer Research95 citations
Semantic Scholar
IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV
M. Grusdat, D. Mcilwain, Hai-Feng C. Xu, V. I. Pozdeev +21 more
2014Cell Death and Differentiation80 citations Open access
Semantic Scholar
Involvement of Toso in activation of monocytes, macrophages, and granulocytes
K. Lang, P. Lang, A. Meryk, A. Pandyra +23 more
2013Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
Semantic Scholar
Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death
A. Pandyra, P. Mullen, C. Goard, Elke Ericson +12 more
2015OncoTarget63 citations Open access
Semantic Scholar
Phosphate Homeostasis, Inflammation and the Regulation of FGF-23
F. Lang, C. Leibrock, A. Pandyra, C. Stournaras +2 more
2018Kidney & Blood Pressure Research62 citations Open access
Semantic Scholar
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17
S. K. Maney, D. Mcilwain, Robin Polz, A. Pandyra +17 more
2015Science Signaling62 citations Open access
Semantic Scholar
Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
Prashant V. Shinde, Hai-Feng C. Xu, S. K. Maney, A. Kloetgen +25 more
2017Journal of Virology55 citations Open access
Semantic Scholar
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
V. Khairnar, V. Duhan, S. K. Maney, N. Honke +24 more
2015Nature Communications52 citations Open access
Semantic Scholar
Reactive oxygen species delay control of lymphocytic choriomeningitis virus
P.-A. Lang, H.-C. Xu, M. Grusdat, D. Mcilwain +16 more
2013Cell Death and Differentiation52 citations Open access
Semantic Scholar
Repurposing the serotonin agonist Tegaserod as an anticancer agent in melanoma: molecular mechanisms and clinical implications
Wei Liu, P. Stachura, Hai-Feng C. Xu, Nikkitha Umesh Ganesh +8 more
2020Journal of experimental & clinical cancer research : CR31 citations Open access
Semantic Scholar
B Cell‐Mediated Maintenance of Cluster of Differentiation 169–Positive Cells Is Critical for Liver Regeneration
K. Behnke, Yuan Zhuang, Hai-Feng C. Xu, Balamurugan Sundaram +14 more
2018Hepatology30 citations Open access
Semantic Scholar
Arenavirus Induced CCL5 Expression Causes NK Cell-Mediated Melanoma Regression
H. Bhat, G. Zaun, T. Hamdan, Judith Lang +24 more
2020Frontiers in Immunology29 citations Open access
Semantic Scholar
Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection.
Hai-Feng C. Xu, Jun Huang, A. Pandyra, Elisabeth Lang +8 more
2017Cell Reports29 citations Open access
Semantic Scholar
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression
H. Kalkavan, P. Sharma, S. Kasper, I. Helfrich +25 more
2017Nature Communications29 citations Open access
Semantic Scholar
A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control
S. Namineni, Tracy O'Connor, Suzanne Faure-Dupuy, P. Johansen +37 more
2020Zeitschrift für Gastroenterologie - German Journal of Gastroenterology26 citations Open access
Semantic Scholar
Deficiency of the B Cell-Activating Factor Receptor Results in Limited CD169+ Macrophage Function during Viral Infection
Hai-Feng C. Xu, Jun Huang, V. Khairnar, V. Duhan +21 more
2015Journal of Virology26 citations Open access
Semantic Scholar
NK Cells Regulate CD8+ T Cell Mediated Autoimmunity
P. Lang, Sarah Q. Crome, Hai-Feng C. Xu, K. Lang +15 more
2020Frontiers in Cellular and Infection Microbiology25 citations Open access
Semantic Scholar
Senescent Tumor CD8+ T Cells: Mechanisms of Induction and Challenges to Immunotherapy
Wei Liu, P. Stachura, Hai-Feng C. Xu, S. Bhatia +3 more
2020Cancers24 citations Open access
Semantic Scholar
SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
P. Sharma, V. Khairnar, I. Madunić, Y. Singh +7 more
2017Cellular Physiology and Biochemistry24 citations Open access
Semantic Scholar
Regiochemical switching in Diels-Alder cycloadditions by change in oxidation state of removable diene sulfur substituents. Synthesis of carbazoles by sequential heteroannulation and Diels-Alder cycloaddition.
T. G. Back, A. Pandyra, J. Wulff
2003Journal of Organic Chemistry24 citations
Semantic Scholar
Glucose transport in lymphocytes
F. Lang, Y. Singh, M. Salker, Ke Ma +3 more
2020Pflügers Archiv: European Journal of Physiology23 citations
Semantic Scholar
iRhom2 inhibits bile duct obstruction–induced liver fibrosis
Balamurugan Sundaram, K. Behnke, Andrea Belancic, Mazin A. Al-Salihi +21 more
2019Science Signaling23 citations
Semantic Scholar
Co-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells
M. Vogt, N. Dienstbier, Julian Schliehe-Diecks, K. Scharov +19 more
2023Cell Death and Disease21 citations Open access
Semantic Scholar
Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death
Joseph Longo, A. Pandyra, P. Stachura, M. Minden +2 more
2020Molecular Oncology21 citations Open access
Semantic Scholar
Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury
Yuan Zhuang, Hai-Feng C. Xu, Prashant V. Shinde, J. Warfsmann +18 more
2019Gut20 citations Open access
Semantic Scholar
BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
Wei Liu, P. Stachura, Hai-Feng C. Xu, R. Váraljai +16 more
2021Cancer Research19 citations Open access
Semantic Scholar
Slow viral propagation during initial phase of infection leads to viral persistence in mice
Hai-Feng C. Xu, Rui-Feng Wang, Prashant V. Shinde, Lara Walotka +11 more
2021Communications Biology18 citations Open access
Semantic Scholar
MYC activity is negatively regulated by a C-terminal lysine cluster
A. R. Wasylishen, M. Kalkat, S. S. Kim, A. Pandyra +7 more
2014Oncogene18 citations
Semantic Scholar
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
Anfei Huang, Prashant V. Shinde, Jun Huang, T. Senff +10 more
2019JCI Insight17 citations Open access
Semantic Scholar
Reply to Honjo et al.: Functional relevant expression of Toso on granulocytes
K. Lang, P. Lang, A. Meryk, A. Pandyra +3 more
2013Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2
Julia Werner, R. Kronberg, P. Stachura, P. Ostermann +8 more
2021Viruses15 citations Open access
Semantic Scholar
Arenaviruses: Old viruses present new solutions for cancer therapy
P. Stachura, Olivia Stencel, Zhe Lu, A. Borkhardt +1 more
2023Frontiers in Immunology14 citations Open access
Semantic Scholar
Targeting tumor cell metabolism via the mevalonate pathway: Two hits are better than one
A. Pandyra, L. Penn
2014Molecular & Cellular Oncology12 citations Open access
Semantic Scholar
Combination Silencer RNA (siRNA) Targeting Bcl-2 Antagonizes siRNA against Thymidylate Synthase in Human Tumor Cell Lines
A. Pandyra, R. Berg, M. Vincent, J. Koropatnick
2007Journal of Pharmacology and Experimental Therapeutics11 citations
Semantic Scholar
A brain organoid/ALL coculture model reveals the AP-1 pathway as critically associated with CNS involvement of BCP-ALL
P. Gebing, Stefanos Loizou, S. Hänsch, Julian Schliehe-Diecks +16 more
2024Blood Advances10 citations Open access
Semantic Scholar
Deciphering the Therapeutic Potential of Novel Pentyloxyamide-Based Class I, IIb HDAC Inhibitors against Therapy-Resistant Leukemia.
Fabian Fischer, Julian Schliehe-Diecks, J.-W. Tu, T. Gangnus +19 more
2024Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
Communicator-Driven Data Preprocessing Improves Deep Transfer Learning of Histopathological Prediction of Pancreatic Ductal Adenocarcinoma
R. Kronberg, L. Haeberle, Melanie Pfaus, Hai-Feng C. Xu +7 more
2022Cancers10 citations Open access
Semantic Scholar
Isotope‐labeled vibrational circular dichroism studies of calmodulin and its interactions with ligands
A. Pandyra, A. Yamniuk, V. Andrushchenko, H. Wieser +1 more
2005Biopolymers10 citations
Semantic Scholar
Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors
P. Stachura, W. Liu, Hai-Feng C. Xu, Agnès Wlodarczyk +12 more
2023Molecular Cancer9 citations Open access
Semantic Scholar
Single MHC‐I Expression Promotes Virus‐Induced Liver Immunopathology
Hai-Feng C. Xu, Jun Huang, A. Pandyra, Piyush Pandey +14 more
2022Hepatology Communications9 citations Open access
Semantic Scholar
A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers
Ersen Kameri, V. Jepsen, P. Stachura, Nadine Rüchel +10 more
2025Frontiers in Public Health7 citations Open access
Semantic Scholar
RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production
S. K. Maney, Hai-Feng C. Xu, Jun Huang, A. Pandyra +16 more
2016Cellular Physiology and Biochemistry7 citations Open access
Semantic Scholar
Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL
P. Stachura, Zhe Lu, R. Kronberg, Hai-Feng C. Xu +11 more
2025Cell Death and Disease6 citations Open access
Semantic Scholar
High-Affinity-Mediated Viral Entry Triggers Innate Affinity Escape Resulting in Type I IFN Resistance and Impaired T Cell Immunity.
Hai-Feng C. Xu, Piyush Pandey, Harry A. Ward, M. Gorzkiewicz +10 more
2024Journal of Immunology6 citations Open access
Semantic Scholar
Integrative multi-omics reveals two biologically distinct groups of pilocytic astrocytoma
D. Picard, J. Felsberg, M. Langini, P. Stachura +21 more
2023Acta Neuropathologica6 citations Open access
Semantic Scholar

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