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Timothy Schappe · SciRah

Researcher profile · Semantic Scholar

Timothy Schappe

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Timothy Schappe — researcher profile on SciRah

h-index: 24
Works: 66
Citations: 3,172

Most-cited papers

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
R. Romee, M. Rosario, M. Berrien-Elliott, J. Wagner +14 more
2016Science Translational Medicine847 citations Open access
Semantic Scholar
CD56bright NK cells exhibit potent antitumor responses following IL-15 priming
J. Wagner, M. Rosario, R. Romee, M. Berrien-Elliott +16 more
2017Journal of Clinical Investigation271 citations Open access
Semantic Scholar
Variants in the CD36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol.
L. Love-Gregory, R. Sherva, Lingwei Sun, J. Wasson +8 more
2008Human Molecular Genetics203 citations Open access
Semantic Scholar
CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas.
Margery Gang, Nancy D. Marin, Pamela Wong, C. Neal +17 more
2020Blood194 citations Open access
Semantic Scholar
Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile.
L. Love-Gregory, R. Sherva, Timothy Schappe, Jian-Shen Qi +4 more
2011Human Molecular Genetics159 citations Open access
Semantic Scholar
The IL-15-based ALT-803 complex enhances FcγRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas
M. Rosario, Bai Liu, Lin Kong, Lynne I. Collins +17 more
2015Clinical Cancer Research139 citations Open access
Semantic Scholar
Donor Memory-like NK cells Persist and Induce Remissions in Pediatric Patients with Relapsed AML after Transplant.
J. Bednarski, Clare Zimmerman, M. Berrien-Elliott, J. Foltz +20 more
2021Blood134 citations Open access
Semantic Scholar
Combining AFM13, a bispecific CD30/CD16 antibody, with cytokine-activated cord blood-derived NK cells facilitates CAR-like responses against CD30+ malignancies
L. Kerbauy, Nancy D. Marin, Mecit Kaplan, P. Banerjee +39 more
2021Clinical Cancer Research126 citations Open access
Semantic Scholar
Multidimensional analyses of donor memory-like NK cells reveal new associations with response after adoptive immunotherapy for leukemia
M. Berrien-Elliott, A. Cashen, Celia C. Cubitt, C. Neal +22 more
2020Cancer Discovery118 citations Open access
Semantic Scholar
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia
M. Berrien-Elliott, J. Foltz, D. Russler-Germain, C. Neal +36 more
2022Science Translational Medicine105 citations Open access
Semantic Scholar
Genetic Ablation of Calcium-independent Phospholipase A2γ Prevents Obesity and Insulin Resistance during High Fat Feeding by Mitochondrial Uncoupling and Increased Adipocyte Fatty Acid Oxidation*
D. J. Mancuso, H. Sims, Kui Yang, M. Kiebish +11 more
2010Journal of Biological Chemistry85 citations Open access
Semantic Scholar
A fusion protein complex that combines IL12, IL15, and IL18 signaling to induce memory-like NK cells for cancer immunotherapy
M. Becker-Hapak, N. Shrestha, Ethan McClain, Michael J. Dee +28 more
2021Cancer immunology research62 citations Open access
Semantic Scholar
Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity
J. Wagner, Pamela Wong, Timothy Schappe, M. Berrien-Elliott +14 more
2020Cell Reports60 citations Open access
Semantic Scholar
The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β
Clarissa S. Craft, T. Pietka, Timothy Schappe, T. Coleman +4 more
2014Diabetes58 citations Open access
Semantic Scholar
Memory-like differentiation enhances NK cell responses to melanoma
Nancy D. Marin, B. Krasnick, M. Becker-Hapak, L. Conant +16 more
2021Clinical Cancer Research54 citations Open access
Semantic Scholar
Cytokine-induced memory-like differentiation enhances unlicensed NK cell anti-leukemia and FcγRIIIa-triggered responses
J. Wagner, M. Berrien-Elliott, M. Rosario, Jeffrey W. Leong +4 more
2016Biology of Blood and Marrow Transplantation52 citations Open access
Semantic Scholar
microRNA-142 is critical for the homeostasis and function of type-1 innate lymphoid cells
M. Berrien-Elliott, Ya-Ping Sun, C. Neal, Aaron R. Ireland +20 more
2019Immunity50 citations Open access
Semantic Scholar
MicroRNA-15/16 antagonizes Myb to control natural killer cell maturation
R. Sullivan, Jeffrey W. Leong, Stephanie E. Schneider, Aaron R. Ireland +6 more
2015Journal of Immunology50 citations Open access
Semantic Scholar
T-BET and EOMES sustain mature human NK cell identity and antitumor function
Pamela Wong, J. Foltz, Li-Wei Chang, C. Neal +24 more
2023Journal of Clinical Investigation49 citations Open access
Semantic Scholar
Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation
J. Foltz, Jennifer Tran, Pamela Wong, Changxu Fan +25 more
2024Science immunology45 citations
Semantic Scholar
Phase 1 trial of N-803, an IL-15 receptor agonist, with rituximab in patients with indolent non-Hodgkin lymphoma
J. Foltz, B. Hess, V. Bachanova, N. Bartlett +22 more
2021Clinical Cancer Research39 citations Open access
Semantic Scholar
PTEN regulates natural killer cell trafficking in vivo
Jeffrey W. Leong, Stephanie E. Schneider, R. Sullivan, B. Parikh +8 more
2014Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Adipose and Muscle Tissue Profile of CD36 Transcripts in Obese Subjects Highlights the Role of CD36 in Fatty Acid Homeostasis and Insulin Resistance
T. Pietka, Timothy Schappe, Caterina Conte, E. Fabbrini +4 more
2014Diabetes Care37 citations Open access
Semantic Scholar
Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice
Niraj Shrestha, P. Chaturvedi, Xiaoyun Zhu, Michael J. Dee +34 more
2023Aging Cell24 citations Open access
Semantic Scholar
Cytokine-Induced Memory-like (ML) NK Cells Persist for > 2 Months Following Adoptive Transfer into Leukemia Patients with a MHC-Compatible Hematopoietic Cell Transplant (HCT)
J. Foltz, M. Berrien-Elliott, C. Neal, M. Foster +6 more
2019Blood23 citations
Semantic Scholar
Flow cytometry-based ex vivo murine NK cell cytotoxicity assay
Pamela Wong, J. Wagner, M. Berrien-Elliott, Timothy Schappe +1 more
2021STAR Protocols19 citations Open access
Semantic Scholar
Variants in the CD 36 gene associate with the metabolic syndrome and high-density lipoprotein cholesterol
L. Love-Gregory, R. Sherva, Lingwei Sun, J. Wasson +8 more
200817 citations
Semantic Scholar
A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells
Celia C. Cubitt, Ethan McClain, M. Becker-Hapak, J. Foltz +11 more
2022Molecular Therapy: Oncolytics16 citations Open access
Semantic Scholar
Neoantigen landscape supports feasibility of personalized cancer vaccine for follicular lymphoma
Cody A. Ramirez, M. Becker-Hapak, K. Singhal, D. Russler-Germain +29 more
2022medRxiv15 citations Open access
Semantic Scholar
Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma
Felicia Gomez, Bryan Fisk, Joshua F. McMichael, Matthew Mosior +27 more
2021medRxiv12 citations Open access
Semantic Scholar
Memory-like differentiation, tumor targeting monoclonal antibodies, and chimeric antigen receptors enhance natural killer cell responses to head and neck cancer
Miriam T. Jacobs, Pamela Wong, A. Zhou, M. Becker-Hapak +23 more
2023Clinical Cancer Research11 citations Open access
Semantic Scholar
Primary Human NK Cell Gene-Editing Reveals a Critical Role for NKG2A in Cytokine-Induced Memory-like NK Cell Responses
M. Berrien-Elliott, Wong Pamela, C. Neal, J. Wagner +5 more
2019Blood11 citations Open access
Semantic Scholar
Induced CD8α identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation
Celia C. Cubitt, Pamela Wong, Hannah K. Dorando, J. Foltz +15 more
2024Journal of Clinical Investigation10 citations Open access
Semantic Scholar
Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation
J. Bednarski, Clare Zimmerman, A. Cashen, S. Desai +6 more
2019Blood10 citations Open access
Semantic Scholar
Memory-like differentiation enhances NK cell responses against colorectal cancer
Nancy D. Marin, M. Becker-Hapak, Wilbur Song, Q. Alayo +17 more
2024Oncoimmunology9 citations Open access
Semantic Scholar
Memory-like NK cell differentiation, inhibitory NKG2A blockade, and improved recognition via antibody or CAR engineering combine to enhance NK cell attack against multiple myeloma.
Alice Y. Zhou, Nancy D. Marin, Sadia A Afrin, Pamela Wong +24 more
2025Journal of Immunology4 citations
Semantic Scholar
Human Cytokine-Induced Memory-like NK Cells Exhibit in Vivo Anti-Leukemia Activity in Xenografted NSG Mice and in Patients with Acute Myeloid Leukemia (AML)
R. Romee, Rosario Maximillian, M. Berrien-Elliott, J. Wagner +6 more
20154 citations Open access
Semantic Scholar
Cytokine-induced memory-like differentiation enhances unlicensed NK cell anti-leukemia and Fc RIIIa-triggered responses
J. Wagner, M. Berrien-Elliott, M. Rosario, Jeffrey W. Leong +4 more
20163 citations
Semantic Scholar
Donor-Derived Memory-like NK Cells for the Treatment of Children and Young Adults with Relapsed AML Following Allo-HCT
Thomas Pfeiffer, Clare Zimmerman, M. Berrien-Elliott, J. Foltz +21 more
2024Transplantation and Cellular Therapy2 citations Open access
Semantic Scholar
Combined IL-12, IL-15 and IL-18 activation induces epigenetic changes in human NK cells during the memory-like state transition
Jennifer Tran, Pamela Wong, Changxu Fan, D. Russler-Germain +7 more
2023Journal of Immunology2 citations Open access
Semantic Scholar
Cytokine-Induced Memory-like NK Cells Have a Distinct Single Cell Transcriptional Profile and Persist for Months in Adult and Pediatric Leukemia Patients after Adoptive Transfer
J. Foltz, M. Berrien-Elliott, D. Russler-Germain, C. Neal +24 more
2021Blood2 citations Open access
Semantic Scholar
Abstract 1546: The CD30/CD16A bispecific innate immune cell engager AFM13 elicits heterogeneous single-cell NK cell responses and effectively triggers memory-like (ML) NK cells
Nancy D. Marin, M. Becker-Hapak, J. Koch, M. Berrien-Elliott +10 more
2019Immunology2 citations
Semantic Scholar
NKG2A Represents an Important Immune Checkpoint for Human Cytokine-Induced Memory-like NK Cells in Patients with AML
M. Berrien-Elliott, R. Romee, J. Wagner, M. Becker-Hapak +5 more
20172 citations
Semantic Scholar
MicroRNA-146a deficiency enhances host protection against murine cytomegalovirus
Pamela Wong, Jeffrey W. Leong, Hyogon Sohn, Lily Chang +19 more
2024European Journal of Immunology1 citations
Semantic Scholar
Mechanisms of Cytokine-Induced NK Cell Therapy: IL-12/15/18 Induce a Unique Transcriptional, Epigenetic, and Functional Human NK Cell Memory Program
Jennifer Tran, J. Foltz, Pamela Wong, Changxu Fan +17 more
2023Blood1 citations Open access
Semantic Scholar
Chimeric Antigen Receptor Modified Memory-like (CAR-ML) NK Cells Exhibit Potent Responses to NK-Resistant Tumors
M. Berrien-Elliott, Margery Gang, Nancy M. Marin Agudelo, Lynne Marsala +7 more
2019Blood1 citations Open access
Semantic Scholar
Abstract 5704: Mass cytometry identifies the expansion, persistence, and immune checkpoints of adoptively transferred memory-like NK cells in patients with leukemia
M. Berrien-Elliott, J. Wagner, R. Romee, M. Becker-Hapak +7 more
2018Immunology1 citations
Semantic Scholar
Inducible T-bet deletion reveals tissue-specific requirements in NKp46+ ILC immunobiology and response to murine cytomegalovirus
Pamela Wong, Yeeun Paik, Lily Chang, Allison Burdi +21 more
2026Nature Communications0 citations Open access
Semantic Scholar
Abstract 6997: Defining mechanisms limiting NK cell function in the multiple myeloma tumor microenvironment
Sadia A Afrin, M. Becker-Hapak, Lyra Morina, Wilbur Song +13 more
2026Cancer Research0 citations
Semantic Scholar
Combination Strategies Enhance NK Cell Therapy for Multiple Myeloma (MM): Memory-like Differentiation, NKG2A Blockade, and Improved Recognition Via BCMA CAR or MM-Targeting Antibodies
Alice Y. Zhou, Nancy D. Marin, Sadia A Afrin, Pamela Wong +24 more
2025Transplantation and Cellular Therapy0 citations Open access
Semantic Scholar

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M. Berrien-Elliott — researcher profile on SciRah
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