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Mecit Kaplan · SciRah

Researcher profile · Semantic Scholar

Mecit Kaplan

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Mecit Kaplan — researcher profile on SciRah

h-index: 19
Works: 44
Citations: 3,629

Most-cited papers

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
En-Li Liu, D. Marin, P. Banerjee, H. Macapinlac +23 more
2020New England Journal of Medicine1,827 citations Open access
Semantic Scholar
Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial
David Marin, Ye Li, R. Başar, H. Rafei +32 more
2024Nature Medicine449 citations Open access
Semantic Scholar
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.
May Daher, R. Başar, Elif Gokdemir, Natalia Baran +51 more
2020Blood257 citations Open access
Semantic Scholar
Targeting the αv integrin-TGF-β axis improves natural killer cell function against glioblastoma stem cells.
Hila Shaim, M. Shanley, R. Başar, May Daher +46 more
2021Journal of Clinical Investigation186 citations Open access
Semantic Scholar
Combining AFM13, a bispecific CD30/CD16 antibody, with cytokine-activated cord blood-derived NK cells facilitates CAR-like responses against CD30+ malignancies
L. Kerbauy, Nancy D. Marin, Mecit Kaplan, P. Banerjee +39 more
2021Clinical Cancer Research126 citations Open access
Semantic Scholar
Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering
Li Li, Vakul Mohanty, Jin-Zhuang Dou, Yuefan Huang +26 more
2023Science Advances112 citations Open access
Semantic Scholar
Blinatumomab Maintenance After Allogeneic Hematopoietic Cell Transplantation for B-lineage Acute Lymphoblastic Leukemia.
Mahmoud R. Gaballa, P. Banerjee, D. Milton, Xian-Li Jiang +25 more
2021Blood84 citations Open access
Semantic Scholar
Allogeneic NK cells with a bispecific innate cell engager in refractory relapsed lymphoma: a phase 1 trial
Y. Nieto, P. Banerjee, I. Kaur, R. Başar +32 more
2025Nature Medicine79 citations Open access
Semantic Scholar
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia
Natalia Baran, A. Lodi, Yogesh Dhungana, Shelley M. Herbrich +51 more
2022Nature Communications60 citations Open access
Semantic Scholar
GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells
En-Li Liu, S. Ang, L. Kerbauy, R. Başar +22 more
2021Frontiers in Immunology58 citations Open access
Semantic Scholar
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells
H. Rafei, R. Başar, S. Acharya, Yu-Sung Hsu +54 more
2025Nature57 citations
Semantic Scholar
CD28 costimulation augments CAR signaling in NK cells via the LCK/CD3ζ/ZAP70 signaling axis
S. Acharya, R. Başar, May Daher, H. Rafei +43 more
2024Cancer Discovery52 citations
Semantic Scholar
A novel immature natural killer cell subpopulation predicts relapse after cord blood transplantation.
Li Li, Han Chen, D. Marin, Y. Xi +24 more
2019Blood Advances37 citations Open access
Semantic Scholar
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML
Bijender Kumar, A. Singh, R. Başar, N. Uprety +46 more
2024Science Translational Medicine36 citations Open access
Semantic Scholar
Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells.
R. Başar, May Daher, N. Uprety, Elif Gokdemir +34 more
2020Blood Advances31 citations Open access
Semantic Scholar
A Phase Two Study of High Dose Blinatumomab in Richter’s Syndrome
P. Thompson, Xian-Li Jiang, P. Banerjee, R. Başar +11 more
2022Leukemia29 citations Open access
Semantic Scholar
Innate Cell Engager (ICE®) AFM13 Combined with Preactivated and Expanded (P+E) Cord Blood (CB)-Derived Natural Killer (NK) Cells for Patients with Refractory CD30-Positive Lymphomas: Final Results
Y. Nieto, P. Banerjee, I. Kaur, L. Griffin +20 more
2023Blood23 citations
Semantic Scholar
Anti–miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response
M. Dragomir, Enrique Fuentes-Mattei, M. Winkle, K. Okubo +35 more
2023Journal of Clinical Investigation22 citations Open access
Semantic Scholar
Innate Cell Engager AFM13 Combined with Preactivated and Expanded Cord Blood-Derived NK Cells for Patients with Double Refractory CD30+ Lymphoma
Y. Nieto, P. Banerjee, I. Kaur, L. Griffin +19 more
2022Blood21 citations Open access
Semantic Scholar
Blinatumomab Is Well Tolerated Maintenance Therapy Following Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia
P. Kebriaei, P. Banerjee, C. Ganesh, Mecit Kaplan +11 more
2019Biology of Blood and Marrow Transplantation16 citations Open access
Semantic Scholar
Abstract CT003: Innate cell engager (ICE®) AFM13 combined with preactivated and expanded cord blood (CB)-derived NK cells for patients with refractory/relapsed CD30+ lymphoma
Y. Nieto, Pinaki Banerjee, I. Kaur, R. Bassett +16 more
2022Cancer Research13 citations
Semantic Scholar
Cord Blood NK Cells Engineered to Express a Humanized CD123-Targeted Chimeric Antigen Receptor (CAR) and IL-15 As Off-the-Shelf Therapy for Acute Myeloid Leukemia
L. Kerbauy, S. Ang, En-Li Liu, P. Banerjee +18 more
201713 citations
Semantic Scholar
Targeting T-Cell Lymphoma Using CD70-Directed Cord Blood-Derived CAR-NK Cells
H. Rafei, R. Başar, S. Acharya, Patrick Zhang +25 more
2023Blood10 citations
Semantic Scholar
Overcoming CD226-related immune evasion in acute myeloid leukemia with CD38 CAR-engineered NK cells
Luciana Melo-Garcia, Achintyan Gangadharan, P. Banerjee, Ye Li +19 more
2025Cell Reports9 citations Open access
Semantic Scholar
Metabolic Engineering and Comparative Performance Studies of Synechocystis sp. PCC 6803 Strains for Effective Utilization of Xylose
Saurabh Ranade, Yan Zhang, Mecit Kaplan, Waqar Majeed +1 more
2015Frontiers in Microbiology9 citations Open access
Semantic Scholar
DAP10 Co-Stimulation Imparts Memory-like Features to CD5 Targeting Cord Blood Derived CAR-NK Cells
R. Başar, May Daher, N. Uprety, Emily Ensley +30 more
2023Blood6 citations Open access
Semantic Scholar
Inhibition of the αv integrin-TGF-β axis improves natural killer cell function against glioblastoma stem cells
Hila Shaim, M. Sanabria, R. Başar, Fang Wang +43 more
2020bioRxiv5 citations Open access
Semantic Scholar
Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor
Natalia Baran, A. Lodi, Yogesh Dhungana, Shannon R. Sweeney +46 more
20204 citations
Semantic Scholar
Engineered cord blood megakaryocytes evade killing by allogeneic T-cells for refractory thrombocytopenia
B. Kumar, V. Afshar-Kharghan, M. Mendt, R. Sackstein +20 more
2022Frontiers in Immunology2 citations Open access
Semantic Scholar
CIS checkpoint deletion enhances the fitness of cord blood derived natural killer cells transduced with a chimeric antigen receptor
May Daher, R. Başar, Elif Gokdemir, Natalia Baran +50 more
2020bioRxiv2 citations Open access
Semantic Scholar
Combining CAR Engineering and CIS Checkpoint Deletion in NK Cells for the Treatment of B Cell Hematologic Malignancies
May Daher, R. Başar, Elif Gokdemir, Natalia Baran +21 more
2019Blood2 citations Open access
Semantic Scholar
Author Correction: Allogeneic NK cells with a bispecific innate cell engager in refractory relapsed lymphoma: a phase 1 trial
Y. Nieto, P. Banerjee, I. Kaur, R. Başar +32 more
2025Nature Medicine1 citations Open access
Semantic Scholar
Large Scale Manufacturing of GMP Grade Cord Blood Derived Megakaryocytes for Chemotherapy Induced Thrombocytopenia
Hila Shaim, M. Mendt, Hani Lee, Bijender Kumar +16 more
2024Blood1 citations
Semantic Scholar
Epigenetic Scarring Leads to Irreversible NK Cell Dysfunction in Myeloid Malignancies
Bijender Kumar, A. Singh, R. Başar, N. Uprety +33 more
2023Blood1 citations Open access
Semantic Scholar
NK Cell Dysfunction in CLL Is Mediated through SHP-1 Signaling and Is Associated with Poor Prognosis
Hila Shaim, H. Rafei, Mecit Kaplan, R. Başar +23 more
2023Blood1 citations Open access
Semantic Scholar
Cord Blood Derived Natural Killer Cells Loaded with a Tetravalent Bispecific Antibody Construct (AFM13) As Off-the-Shelf Cell Therapy for CD30+ Malignancies
L. Kerbauy, Mecit Kaplan, P. Banerjee, F. Lim +17 more
2018Blood1 citations Open access
Semantic Scholar
Evaluation of T Cell Compartment By Mass Cytometry Reveals Distinct Patterns of Expression of Exhaustion Markers in Chronic Lymphocytic Leukemia
M. Muftuoglu, Li Li, D. Mak, Jared K. Burks +25 more
20171 citations
Semantic Scholar
Abstract 142: A universal multi-receptor NK cell platform engineered for synergistic combination with antibody and T-cell engager therapies.
R. Başar, Bin Liu, N. Uprety, Francia Reyes Silva +24 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 5194: Oncolytic virus infected tumors drive AP-1 and IRF signaling in NK cells to sustain anti tumor activity
Hila Shaim, Cheryl Jiang, M. Shanley, H. Rafei +40 more
2026Cancer Research0 citations
Semantic Scholar
Long-term follow-up: blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia.
Jennifer Miatech, D. Milton, Mahmoud R. Gaballa, P. Banerjee +25 more
2026Haematologica0 citations Open access
Semantic Scholar
Abstract 6396: CREM is a regulatory checkpoint of CAR and IL-15 signaling in NK cells
H. Rafei, R. Başar, S. Acharya, Yu-Sung Hsu +46 more
2025Cancer Research0 citations
Semantic Scholar
GMP compliant CRISPR/Cas9 gene editing of B2 microglobulin in cord blood derived megakaryocytes and platelets for patients with refractory thrombocytopenia
Hila Shaim, M. Mendt, Hani Lee, Bijender Kumar +16 more
2025Blood0 citations
Semantic Scholar
531 AFM13-targeted blood and cord-blood-derived memory-like NK cells as therapy for CD30+ malignancies
L. Kerbauy, Nancy D. Marin, Mecit Kaplan, P. Banerjee +36 more
20200 citations Open access
Semantic Scholar
Next Generation CRISPR Gene-Edited and Off-the-Shelf Virus-Specific T-Cells for the Immunocompromised Patient
R. Başar, May Daher, N. Uprety, Elif Gokdemir +20 more
2019Blood0 citations
Semantic Scholar

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