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J. Bednarski · SciRah

Researcher profile · Semantic Scholar

J. Bednarski

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J. Bednarski — researcher profile on SciRah

h-index: 26
Works: 106
Citations: 2,650

Most-cited papers

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner
P. Collins, Caitlin E. Purman, Sofia I. Porter, Vincent Nganga +7 more
2020Nature Communications195 citations Open access
Semantic Scholar
SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.
É. Haddad, B. Logan, Linda M. Griffith, R. Buckley +61 more
2018Blood154 citations Open access
Semantic Scholar
A Novel Secreted Protein, MYR1, Is Central to Toxoplasma’s Manipulation of Host Cells
Magdalena Franco, Michael W. Panas, Nicole D. Marino, M. W. Lee +6 more
2016mBio153 citations Open access
Semantic Scholar
H2AX Prevents CtIP-Mediated DNA End Resection and Aberrant Repair in G1-Phase Lymphocytes
Beth A. Helmink, Anthony T. Tubbs, Yair Dorsett, J. Bednarski +7 more
2010Nature138 citations Open access
Semantic Scholar
Donor Memory-like NK cells Persist and Induce Remissions in Pediatric Patients with Relapsed AML after Transplant.
J. Bednarski, Clare Zimmerman, M. Berrien-Elliott, J. Foltz +20 more
2021Blood134 citations Open access
Semantic Scholar
At the intersection of DNA damage and immune responses
J. Bednarski, B. Sleckman
2019Nature reviews. Immunology133 citations Open access
Semantic Scholar
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
Beth A. Helmink, Andrea L. Bredemeyer, Baeck-seung Lee, Ching‐Yu Huang +7 more
2009Journal of Experimental Medicine100 citations Open access
Semantic Scholar
Cell circuits between B cell progenitors and IL-7+ mesenchymal progenitor cells control B cell development
Chris Fistonich, S. Zehentmeier, J. Bednarski, Runfeng Miao +3 more
2018Journal of Experimental Medicine87 citations Open access
Semantic Scholar
Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain-of-function.
Jahnavi Aluri, Alicia Bach, Saara Kaviany, Luana Chiquetto Paracatu +32 more
2020Blood77 citations Open access
Semantic Scholar
Measuring the impact of newborn screening on survival after hematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium
Monica S. Thakar, B. Logan, J. Puck, Elizabeth A. Dunn +61 more
2023The Lancet70 citations Open access
Semantic Scholar
Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation
E. Gapud, Yair Dorsett, B. Yin, E. Callen +9 more
2011Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma
Olivia I. Koues, Rodney A. Kowalewski, Li-Wei Chang, Sarah C. Pyfrom +8 more
2014Immunity64 citations Open access
Semantic Scholar
Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey
Alice Y. Chan, J. Leiding, Xue-Rong Liu, B. Logan +56 more
2020Frontiers in Immunology63 citations Open access
Semantic Scholar
Lymphocyte Development: Integration of DNA Damage Response Signaling
J. Bednarski, B. Sleckman
2012Advances in Immunology56 citations Open access
Semantic Scholar
RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation
J. Bednarski, Andrew Nickless, Deepta Bhattacharya, Rupesh H. Amin +2 more
2012Journal of Experimental Medicine51 citations Open access
Semantic Scholar
RAG-mediated DNA double-strand breaks activate a cell type–specific checkpoint to inhibit pre–B cell receptor signals
J. Bednarski, R. Pandey, Emily Schulte, Lynn S. White +11 more
2016Journal of Experimental Medicine46 citations Open access
Semantic Scholar
Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation
J. Foltz, Jennifer Tran, Pamela Wong, Changxu Fan +25 more
2024Science immunology45 citations
Semantic Scholar
Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine.
J. Bednarski, R. Warner, Tharaknath Rao, F. Leonetti +6 more
2003Arthritis & Rheumatism45 citations Open access
Semantic Scholar
Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers
M. Dorsey, N. Wright, Natalia Chaimowitz, B. D. Dávila Saldaña +55 more
2020Journal of Clinical Immunology44 citations Open access
Semantic Scholar
Outcomes Following Treatment for Adenosine Deaminase Deficient Severe Combined Immunodeficiency: A Report from the PIDTC.
G. Cuvelier, B. Logan, S. Prockop, R. Buckley +46 more
2022Blood40 citations Open access
Semantic Scholar
The Ataxia Telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements
Natalie C. Steinel, Baeck-seung Lee, Anthony T. Tubbs, J. Bednarski +5 more
2013Journal of Experimental Medicine40 citations Open access
Semantic Scholar
The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions
C. Dvorak, Elie Haddad, J. Heimall, Elizabeth A. Dunn +47 more
2022Journal of Allergy and Clinical Immunology33 citations Open access
Semantic Scholar
Safety of Probiotics Among High-Risk Pediatric Hematopoietic Stem Cell Transplant Recipients
Arhanti Sadanand, J. Newland, J. Bednarski
2019Infectious Disease and Therapy33 citations Open access
Semantic Scholar
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment
Michael D. Keller, P. Hanley, Yueh-Yun Chi, Paibel I Aguayo-Hiraldo +45 more
2024Nature Communications26 citations Open access
Semantic Scholar
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling
Zev J. Greenberg, Darlene A. Monlish, Rachel L. Bartnett, Yihu Yang +4 more
2019Journal of Immunology23 citations Open access
Semantic Scholar
Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
Sanghyun P. Kim, S. Srivatsan, Monique Chavez, C. Shirai +9 more
2021Cell Reports22 citations Open access
Semantic Scholar
Genotype, Oxidase Status, and Preceding Infection or Autoinflammation Do Not Affect Allogeneic HCT Outcomes for CGD.
J. Leiding, Danielle E. Arnold, S. Parikh, B. Logan +65 more
2023Blood20 citations Open access
Semantic Scholar
RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex
Deepti Soodgupta, Lynn S. White, Wei Yang, R. Johnston +6 more
2019Cell Reports20 citations Open access
Semantic Scholar
Immune Reconstitution in Pediatric Patients Following Hematopoietic Cell Transplant for Non-malignant Disorders
Sima T. Bhatt, J. Bednarski
2020Frontiers in Immunology19 citations Open access
Semantic Scholar
A Novel Benzodiazepine Increases the Sensitivity of B Cells to Receptor Stimulation with Synergistic Effects on Calcium Signaling and Apoptosis*
J. Bednarski, C. Lyssiotis, R. Roush, Anthony E. Boitano +2 more
2004Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Post-Transplant Late Complications Increase Over Time for Patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) Landmark Study
H. Eissa, Monica S. Thakar, Ami J. Shah, Brent R. Logan +54 more
2023Journal of Allergy and Clinical Immunology15 citations Open access
Semantic Scholar
Immunological Findings and Clinical Outcomes of Infants With Positive Newborn Screening for Severe Combined Immunodeficiency From a Tertiary Care Center in the U.S.
V. Mantravadi, J. Bednarski, M. Ritter, H. Gu +4 more
2021Frontiers in Immunology15 citations Open access
Semantic Scholar
A single‐center experience using alemtuzumab, fludarabine, melphalan, and thiotepa as conditioning for transplantation in pediatric patients with chronic granulomatous disease
Sima T. Bhatt, G. Schulz, M. Hente, Ashley Slater +3 more
2020Pediatric Blood & Cancer14 citations
Semantic Scholar
Immune Reconstitution and Infection Patterns after Early Alemtuzumab and Reduced Intensity Transplantation for Nonmalignant Disorders in Pediatric Patients.
Sima T. Bhatt, J. Bednarski, J. Berg, K. Trinkaus +21 more
2019Biology of Blood and Marrow Transplantation14 citations Open access
Semantic Scholar
Incidence and treatment of hemophagocytic lymphohistiocytosis in hospitalized children with Ehrlichia infection
S. Cabler, P. Hogan, Stephanie A. Fritz, J. Bednarski +1 more
2020Pediatric Blood & Cancer12 citations
Semantic Scholar
Integrated signaling in developing lymphocytes
J. Bednarski, B. Sleckman
2012Cell Cycle12 citations Open access
Semantic Scholar
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Beth A. Helmink, Anthony T. Tubbs, Yair Dorsett, J. Bednarski +7 more
2011Nature11 citations Open access
Semantic Scholar
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress
Dylan Fingerman, David R. O’Leary, A. R. Hansen, Thi Tran +16 more
2023bioRxiv10 citations Open access
Semantic Scholar
Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation
J. Bednarski, Clare Zimmerman, A. Cashen, S. Desai +6 more
2019Blood10 citations Open access
Semantic Scholar
Omenn Syndrome Presenting with Striking Erythroderma and Extreme Lymphocytosis in a Newborn
R. Zafar, A. V. Ver Heul, A. Beigelman, J. Bednarski +4 more
2017Pediatric dermatology10 citations
Semantic Scholar
Maternal T cell engraftment interferes with HLA typing in severe combined immune deficiency
Chang Liu, B. Duffy, J. Bednarski, Cecelia Calhoun +4 more
2016American Journal of Clinical Pathology10 citations Open access
Semantic Scholar
Nuclease‐independent functions of RAG1 direct distinct DNA damage responses in B cells
R. Johnston, Brendan Mathias, Stephanie J Crowley, Haley Schmidt +4 more
2022EMBO Reports9 citations Open access
Semantic Scholar
Letermovir as cytomegalovirus prophylaxis in children undergoing allogeneic hematopoietic cell transplantation
Thomas Pfeiffer, Christine R. Lockowitz, S. Shenoy, Melissa Mavers +3 more
2024Bone Marrow Transplantation8 citations
Semantic Scholar
MYSM1 attenuates DNA damage signals triggered by physiologic and genotoxic DNA breaks
Brendan Mathias, David R. O’Leary, Nermina Saucier, Faiz Ahmad +9 more
2023Journal of Allergy and Clinical Immunology8 citations Open access
Semantic Scholar
Recovery from COVID-19 in a Child with Chronic Granulomatous Disease and T Cell Lymphopenia
V. Mantravadi, Suong T. Nguyen, S. Morley, J. Bednarski +2 more
2020Journal of Clinical Immunology8 citations Open access
Semantic Scholar
Hematopoietic KIT D816Y mutation presenting as in utero aggressive systemic mastocytosis with response to midostaurin.
Dayne H. Voelker, J. Bednarski, Elizabeth L Nieman, M. Carter +1 more
2022Journal of Allergy and Clinical Immunology: In Practice7 citations
Semantic Scholar
Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia
Roshini S. Abraham, Amrita Basu, J. Heimall, Elizabeth A. Dunn +53 more
2024Clinical Immunology6 citations Open access
Semantic Scholar
A Case of Severe Combined Immunodeficiency Missed by Newborn Screening
M. Kitcharoensakkul, Jahnavi Aluri, Ibrahim Elsharkawi, Ashley L. Steed +4 more
2021Journal of Clinical Immunology6 citations Open access
Semantic Scholar
Pediatric Necrobiotic Xanthogranuloma as a Novel Phenotype of IKAROS Gain of Function
R. Guess, George J. Harocopos, J. Bednarski, Lynn M Hassmann +1 more
2023Journal of Clinical Immunology4 citations Open access
Semantic Scholar
Bclaf1 Promotes Maintenance and Self-Renewal of Fetal Hematopoietic Stem Cells
Lynn S. White, Deepti Soodgupta, R. Johnston, Jeffrey A. Magee +1 more
2018Blood4 citations Open access
Semantic Scholar

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