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J. Koch · SciRah

Researcher profile · Semantic Scholar

J. Koch

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J. Koch — researcher profile on SciRah

h-index: 40
Works: 118
Citations: 4,743

Most-cited papers

TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy
Z. Grada, M. Hegde, T. Byrd, D. Shaffer +11 more
2013Molecular Therapy: Nucleic Acids443 citations Open access
Semantic Scholar
Activating natural cytotoxicity receptors of natural killer cells in cancer and infection.
J. Koch, A. Steinle, C. Watzl, O. Mandelboim
2013Trends in immunology316 citations
Semantic Scholar
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing.
Danijela Koppers-Lalic, E. Reits, M. Ressing, Andrea D. Lipińska +11 more
2005Proceedings of the National Academy of Sciences of the United States of America211 citations Open access
Semantic Scholar
Functional Dissection of the Transmembrane Domains of the Transporter Associated with Antigen Processing (TAP)*
J. Koch, Renate Guntrum, Susanne Heintke, Christoph Kyritsis +1 more
2004Journal of Biological Chemistry169 citations Open access
Semantic Scholar
TEM8/ANTXR1-specific CAR T cells as a targeted therapy for triple-negative breast cancer
T. Byrd, Kristen Fousek, A. Pignata, C. Szot +21 more
2017Cancer Research136 citations Open access
Semantic Scholar
Combining AFM13, a bispecific CD30/CD16 antibody, with cytokine-activated cord blood-derived NK cells facilitates CAR-like responses against CD30+ malignancies
L. Kerbauy, Nancy D. Marin, Mecit Kaplan, P. Banerjee +39 more
2021Clinical Cancer Research126 citations Open access
Semantic Scholar
RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation.
O. N. Kuvardina, J. Herglotz, S. Kolodziej, N. Kohrs +14 more
2015Blood123 citations Open access
Semantic Scholar
New prospects on the NKG2D/NKG2DL system for oncology
E. Ullrich, J. Koch, A. Cerwenka, A. Steinle
2013Oncoimmunology122 citations Open access
Semantic Scholar
CD16A Activation of NK Cells Promotes NK Cell Proliferation and Memory-Like Cytotoxicity against Cancer Cells
J. Pahl, J. Koch, Jana-Julia Götz, A. Arnold +5 more
2018Cancer immunology research120 citations Open access
Semantic Scholar
The C Terminus of the Alb3 Membrane Insertase Recruits cpSRP43 to the Thylakoid Membrane*
S. Falk, S. Ravaud, J. Koch, I. Sinning
2009Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Varicellovirus UL49.5 Proteins Differentially Affect the Function of the Transporter Associated with Antigen Processing, TAP
Danijela Koppers-Lalic, M. Verweij, Andrea D. Lipińska, Ying Wang +16 more
2008PLoS Pathogens92 citations Open access
Semantic Scholar
Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids
Ariane Giannattasio, Sandra Weil, S. Kloess, Nariman Ansari +5 more
2015BMC Cancer87 citations Open access
Semantic Scholar
IL‐2‐activated haploidentical NK cells restore NKG2D‐mediated NK‐cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA
S. Kloess, S. Huenecke, Daniel Piechulek, R. Esser +10 more
2010European Journal of Immunology87 citations Open access
Semantic Scholar
Mechanisms of Tumor and Viral Immune Escape from Natural Killer Cell-Mediated Surveillance
A. Groth, S. Klöss, Elke Pogge von Strandmann, U. Koehl +1 more
2011Journal of Innate Immunity78 citations
Semantic Scholar
Structure and Dynamics of Membrane-associated ICP47, a Viral Inhibitor of the MHC I Antigen-processing Machinery*
C. Aisenbrey, C. Sizun, J. Koch, M. Herget +3 more
2006Journal of Biological Chemistry71 citations Open access
Semantic Scholar
BAG-6, a jack of all trades in health and disease
Janina Binici, J. Koch
2013Cellular and Molecular Life Sciences68 citations
Semantic Scholar
Preclinical evaluation of AFM24, a novel CD16A-specific innate immune cell engager targeting EGFR-positive tumors
S. Wingert, U. Reusch, S. Knackmuss, M. Kluge +12 more
2021mAbs65 citations Open access
Semantic Scholar
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers.
S. Pinto, J. Pahl, A. Schottelius, P. Carter +1 more
2022Trends in immunology62 citations Open access
Semantic Scholar
Redirected optimized cell killing (ROCK®): A highly versatile multispecific fit-for-purpose antibody platform for engaging innate immunity
Kristina Ellwanger, U. Reusch, Ivica Fucek, S. Wingert +8 more
2019mAbs58 citations Open access
Semantic Scholar
Regulatory properties and interaction of the C- and N-terminal domains of BetP, an osmoregulated betaine transporter from Corynebacterium glutamicum.
Vera Ott, J. Koch, Kira Späte, S. Morbach +1 more
2008Biochemistry56 citations
Semantic Scholar
Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma
Sandra Weil, Stefanie Memmer, A. Lechner, V. Huppert +13 more
2017Frontiers in Immunology52 citations Open access
Semantic Scholar
Increased sMICA and TGFβ1 levels in HNSCC patients impair NKG2D-dependent functionality of activated NK cells
S. Klöss, N. Chambron, Tanja Gardlowski, L. Arseniev +5 more
2015Oncoimmunology51 citations Open access
Semantic Scholar
NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients
S. Rusakiewicz, A. Perier, M. Semeraro, J. Pitt +40 more
2017Oncoimmunology48 citations Open access
Semantic Scholar
The Varicellovirus-Encoded TAP Inhibitor UL49.5 Regulates the Presentation of CTL Epitopes by Qa-1b1
T. van Hall, Sandra Laban, Danijela Koppers-Lalic, J. Koch +4 more
2007Journal of Immunology48 citations
Semantic Scholar
Identification of two interaction sites in SecY that are important for the functional interaction with SecA.
E. O. van der Sluis, N. Nouwen, J. Koch, J. de Keyzer +3 more
2006Journal of Molecular Biology48 citations Open access
Semantic Scholar
Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity.
C. Wichmann, Y. Becker, L. Chen-Wichmann, V. Vogel +8 more
2010Blood47 citations
Semantic Scholar
Membrane Topology of the Transporter Associated with Antigen Processing (TAP1) within an Assembled Functional Peptide-loading Complex*
S. Schrodt, J. Koch, R. Tampé
2006Journal of Biological Chemistry47 citations Open access
Semantic Scholar
A Soluble Fragment of the Tumor Antigen BCL2-associated Athanogene 6 (BAG-6) Is Essential and Sufficient for Inhibition of NKp30 Receptor-dependent Cytotoxicity of Natural Killer Cells*
Janina Binici, Jessica Hartmann, J. Herrmann, C. Schreiber +7 more
2013Journal of Biological Chemistry46 citations Open access
Semantic Scholar
The first N‐terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding
J. Koch, Renate Guntrum, R. Tampé
2006FEBS Letters46 citations Open access
Semantic Scholar
Natural killer and dendritic cells collaborate in the immune response induced by the vaccine against uterine cervical cancer
I. Langers, V. Renoux, A. Reschner, A. Touzé +5 more
2014European Journal of Immunology45 citations Open access
Semantic Scholar
The Stalk Domain and the Glycosylation Status of the Activating Natural Killer Cell Receptor NKp30 Are Important for Ligand Binding*
Jessica Hartmann, Thuy Tran, Janina Kaudeer, K. Oberle +11 more
2012Journal of Biological Chemistry45 citations Open access
Semantic Scholar
A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors
Jessica Hartmann, Robert C. Münch, Ruth-Therese Freiling, Irene C Schneider +6 more
2018Molecular Therapy: Methods & Clinical Development44 citations Open access
Semantic Scholar
Cetuximab Reconstitutes Pro-Inflammatory Cytokine Secretions and Tumor-Infiltrating Capabilities of sMICA-Inhibited NK Cells in HNSCC Tumor Spheroids
S. Klöss, N. Chambron, Tanja Gardlowski, Sandra Weil +7 more
2015Frontiers in Immunology41 citations Open access
Semantic Scholar
Generation of an HFRS patient‐derived neutralizing recombinant antibody to Hantaan virus G1 protein and definition of the neutralizing domain
M. Liang, M. Mahler, J. Koch, Yan Ji +3 more
2003Journal of Medical Virology41 citations
Semantic Scholar
Epstein-Barr Viral BNLF2a Protein Hijacks the Tail-anchored Protein Insertion Machinery to Block Antigen Processing by the Transport Complex TAP*
A. Wycisk, Jia-Chen Lin, Sandra Loch, K. Hobohm +6 more
2011Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Peptides as drugs: from screening to application.
U. Dietrich, R. Dürr, J. Koch
2013Current Pharmaceutical Biotechnology38 citations
Semantic Scholar
Peptide mimotopes recognized by antibodies cetuximab and matuzumab induce a functionally equivalent anti-EGFR immune response
C. Hartmann, N. Müller, A. Blaukat, J. Koch +2 more
2010Oncogene38 citations
Semantic Scholar
The Varicellovirus UL49.5 Protein Blocks the Transporter Associated with Antigen Processing (TAP) by Inhibiting Essential Conformational Transitions in the 6+6 Transmembrane TAP Core Complex1
M. Verweij, Danijela Koppers-Lalic, Sandra Loch, F. Klauschies +9 more
2008Journal of Immunology38 citations Open access
Semantic Scholar
Signaling of a Varicelloviral Factor across the Endoplasmic Reticulum Membrane Induces Destruction of the Peptide-loading Complex and Immune Evasion*
Sandra Loch, F. Klauschies, Christian Schölz, M. Verweij +3 more
2008Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses.
M. Verweij, Andrea D. Lipińska, Danijela Koppers-Lalic, Edwin Quinten +6 more
2011Molecular Immunology34 citations
Semantic Scholar
Engineering ATPase Activity in the Isolated ABC Cassette of Human TAP1*
R. Ernst, J. Koch, Carsten Horn, R. Tampé +1 more
2006Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Inhibition of HIV‐1 by a Peptide Ligand of the Genomic RNA Packaging Signal Ψ
J. Dietz, J. Koch, Ajit Kaur, C. Raja +12 more
2008ChemMedChem33 citations
Semantic Scholar
Preclinical Characterization of AFM26, a Novel B Cell Maturation Antigen (BCMA)-Directed Tetravalent Bispecific Antibody for High Affinity Retargeting of NK Cells Against Myeloma
T. Ross, U. Reusch, S. Wingert, T. Haneke +15 more
2018Blood30 citations Open access
Semantic Scholar
Functional Characterization of Two scFv-Fc Antibodies from an HIV Controller Selected on Soluble HIV-1 Env Complexes: A Neutralizing V3- and a Trimer-Specific gp41 Antibody
Maria Trott, S. Weiss, Sascha Antoni, J. Koch +3 more
2014PLoS ONE30 citations Open access
Semantic Scholar
Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1.
Gabriele Plewnia, Katrin Schulze, C. Hunte, R. Tampé +1 more
2007Journal of Molecular Biology25 citations
Semantic Scholar
Natural killer cells in HIV-1 infection: a double-edged sword.
Jessica Funke, R. Dürr, U. Dietrich, J. Koch
2011AIDS Reviews24 citations
Semantic Scholar
Recombinant Antibodies to Arm Cytotoxic Lymphocytes in Cancer Immunotherapy
J. Koch, M. Tesar
2017Transfusion Medicine and Hemotherapy23 citations Open access
Semantic Scholar
Single residue within the antigen translocation complex TAP controls the epitope repertoire by stabilizing a receptive conformation
Christoph Baldauf, S. Schrodt, M. Herget, J. Koch +1 more
2010Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain.
Katharina Krauskopf, J. Gebel, S. Kazemi, M. Tuppi +6 more
2018Structure22 citations Open access
Semantic Scholar
Exploring the minimal functional unit of the transporter associated with antigen processing
J. Koch, Renate Guntrum, R. Tampé
2005FEBS Letters21 citations
Semantic Scholar

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A. Steinle — researcher profile on SciRah

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M. Ressing — researcher profile on SciRah

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E. Rajkovic — researcher profile on SciRah

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Sandra Loch — researcher profile on SciRah

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