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L. Xue · SciRah

Researcher profile · Semantic Scholar

L. Xue

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L. Xue — researcher profile on SciRah

h-index: 22
Works: 41
Citations: 3,979

Most-cited papers

Activating mutations in ALK provide a therapeutic target in neuroblastoma
Rani E. George, T. Sanda, M. Hanna, S. Fröhling +17 more
2008Nature904 citations Open access
Semantic Scholar
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)
Quan-Geng Zhang, R. Siebert, Minhong Yan, B. Hinzmann +15 more
1999Nature Genetics402 citations
Semantic Scholar
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors
H. Hara, Chitose Ishihara, A. Takeuchi, Takayuki Imanishi +12 more
2007Nature Immunology360 citations
Semantic Scholar
Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma1
Qian Zhang, P. N. Raghunath, L. Xue, M. Majewski +5 more
2002Journal of Immunology293 citations Open access
Semantic Scholar
Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis.
A. Słupianek, M. Nieborowska-Skorska, G. Hoser, A. Morrione +5 more
2001Cancer Research272 citations
Semantic Scholar
Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy
T. Webb, J. Slavish, R. George, A. T. Look +5 more
2009Expert Review of Anticancer Therapy234 citations Open access
Semantic Scholar
Targeted Inhibition of the Molecular Chaperone Hsp90 Overcomes ALK Inhibitor Resistance in Non-Small Cell Lung Cancer
J. Sang, J. Acquaviva, Julie C. Friedland, Donald L. Smith +14 more
2013Cancer Discovery215 citations Open access
Semantic Scholar
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells
L. Xue, S. Morris, C. Orihuela, E. Tuomanen +3 more
2003Nature Immunology203 citations
Semantic Scholar
The emerging normal and disease-related roles of anaplastic lymphoma kinase.
K. Pulford, L. Lamant, E. Espinos, Q. Jiang +4 more
2004Cellular and Molecular Life Sciences (CMLS)149 citations
Semantic Scholar
Role of signal transducer and activator of transcription 5 in nucleophosmin/ anaplastic lymphoma kinase-mediated malignant transformation of lymphoid cells.
Malgorzata Nieborowska‐Skorska, A. Słupianek, L. Xue, Qian Zhang +5 more
2001Cancer Research126 citations
Semantic Scholar
Alk+ CD30+ lymphomas: a distinct molecular genetic subtype of non‐hodgkin's lymphoma
S. Morris, L. Xue, Zhi-Gui Ma, M. Kinney
2001British Journal of Haematology121 citations Open access
Semantic Scholar
Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
2007Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol
A. Lasek, Jana P. Lim, C. L. Kliethermes, Karen H. Berger +10 more
2011PLoS ONE99 citations Open access
Semantic Scholar
Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis.
J. Weiss, C. Xue, Ted S. Benice, L. Xue +2 more
2012Pharmacology, Biochemistry and Behavior98 citations
Semantic Scholar
Emu-BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF-kappaB pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma.
Zhao-Yang Li, Hong-Sheng Wang, L. Xue, Dong-Mi Shin +11 more
2009Blood59 citations Open access
Semantic Scholar
Cell Type-Specific Regulation of ITAM-Mediated NF-κB Activation by the Adaptors, CARMA1 and CARD91
H. Hara, Chitose Ishihara, A. Takeuchi, L. Xue +4 more
2008Journal of Immunology51 citations Open access
Semantic Scholar
Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.
Rong-Shi Li, L. Xue, Tong Zhu, Q. Jiang +10 more
2006Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Phospholipase Cγ2 Provides Survival Signals via Bcl2 and A1 in Different Subpopulations of B Cells*
R. Wen, Yu-Hong Chen, L. Xue, James Schuman +3 more
2003Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Cell Type-Specific Regulation of ITAM-Mediated NF- B Activation by the Adaptors, CARMA1 and CARD9
H. Hara, Chitose Ishihara, A. Takeuchi, L. Xue +4 more
200839 citations
Semantic Scholar
Oncogenic protein tyrosine kinases
K. Pulford, L. Lamant, E. Espinos, Q. Jiang +4 more
2004Cellular and Molecular Life Sciences (CMLS)39 citations
Semantic Scholar
B Cell Lymphoma 10 Is Essential for FcεR-Mediated Degranulation and IL-6 Production in Mast Cells1
Yu-Hong Chen, B. Pappu, H. Zeng, L. Xue +4 more
2007Journal of Immunology27 citations Open access
Semantic Scholar
Hammerhead ribozyme-mediated cleavage of the fusion transcript NPM-ALK associated with anaplastic large-cell lymphoma.
Gabriele Hübinger, E. Wehnes, L. Xue, S. Morris +1 more
2003Experimental Hematology22 citations Open access
Semantic Scholar
T Cell Receptor-mediated Activation of CD4+CD44hi T Cells Bypasses Bcl10
H. Zeng, Yu-Hong Chen, Mei Yu, L. Xue +4 more
2008Journal of Biological Chemistry14 citations Open access
Semantic Scholar
B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells.
Yu-Hong Chen, B. Pappu, H. Zeng, L. Xue +4 more
2007Journal of Immunology12 citations
Semantic Scholar
Bcl10 is an essential regulator for A20 gene expression
Wu Xu, L. Xue, Yi Sun, A. Henry +3 more
2013Journal of physiology and biochemistry8 citations
Semantic Scholar
Bcl 10 plays a critical role in NF-B activation induced by G protein-coupled receptors
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
20077 citations
Semantic Scholar
[Detection of ROS1 gene rearrangement by FISH and analysis of its clinical features in non-small cell lung cancer patients].
Hong-Xia Cheng, L. Ye, L. Xue
2014Zhonghua zhong liu za zhi [Chinese journal of oncology]5 citations
Semantic Scholar
Preclinical activity of the Hsp90 inhibitor, ganetespib, in ALK- and ROS1-driven cancers.
D. Proia, J. Acquaviva, Q. Jiang, L. Xue +6 more
20125 citations
Semantic Scholar
[Detection of ROS1 gene rearrangement by FISH and analysis of its clinical features in non-small cell lung cancer patients].
Hong-Xia Cheng, L. Ye, L. Xue
20144 citations
Semantic Scholar
CARD 19, a novel regulator of the TAK1/NF-κB pathway in self-reactive B cells
Yongwei Zheng, Mei Yu, Yu-Hong Chen, L. Xue +5 more
2023Journal of Immunology3 citations Open access
Semantic Scholar
Erratum: Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors (Proceedings of the National Academy of Sciences of the United States of America (January 2, 2007) 1, 104, (145-150) DOI: 10.1073/pnas.0601894104)
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
20073 citations Open access
Semantic Scholar
CARD19, a Novel Negative Regulator of B-Cell Tolerance
Yongwei Zheng, Mei Yu, Yu-Hong Chen, L. Xue +6 more
2021Blood1 citations Open access
Semantic Scholar
Abstract 1930: The unknown piece of the pie: Molecular markers in triple-negative lung cancer.
B. Schweitzer, Kasey D. Lawrence, J. Handshoe, Rachel Skelton +4 more
20131 citations
Semantic Scholar
Abstract 2220: Insight ALK ScreenTM, a highly sensitive and specific RT-qPCR first-line screening assay for comprehensive detection of all oncogenic anaplastic lymphoma kinase (ALK) fusions: clinical validation
D. Hout, L. Xue, P. Choppa, J. Handshoe +4 more
20111 citations
Semantic Scholar
B-cell expansion as a precursor to splenic MZ lymphoma (MZ) and noncanonical NF-{kappa}B pathways generating marginal zone E{micro}-BCL10 mice exhibit constitutive activation of both canonical
H. Morse, M. Sangster, C. Orihuela, E. Tuomanen +8 more
20091 citations
Semantic Scholar
ROS 1 gene rearrangement and clinicopathological characteristics in Chinese NSCLC patients
Wenbo Ke, Zhi-Gao Xu, L. Xue
20160 citations
Semantic Scholar
[Construction of a repeat-free dual color fluorescent in situ hybridization probe for ROS1 gene in non-small cell lung cancer diagnosis].
Hong-Xia Cheng, L. Ye, L. Xue
20140 citations
Semantic Scholar
[Construction of a repeat-free dual color fluorescent in situ hybridization probe for ROS1 gene in non-small cell lung cancer diagnosis].
Hong-Xia Cheng, L. Ye, L. Xue
2014Zhonghua bing li xue za zhi = Chinese journal of pathology0 citations
Semantic Scholar
Initial validation of a highly sensitive RT-qPCR assay for detecting all fusions and wild-type upregulation of ALK.
David R. Hout, J. Nickols, L. Xue, M. Skokan +4 more
2011Journal of Clinical Oncology0 citations
Semantic Scholar
A method for the diagnosis and treatment of cancer between the anti-anaplastic lymphoma kinase (ALK) kinase inhibitors and compositions
斯蒂芬 W. 莫里斯, Q. Jiang, Xiao-Li Cui, L. Xue
20110 citations
Semantic Scholar
Constitutive Activation of the Canonical NF-κB Signaling Pathway and Expanded Populations of Splenic Marginal Zone B Cells Characterize Em-BCL10 Transgenic Mice.
Zhao-Yang Li, L. Xue, Dong-Mi Shin, Chen-Feng Qi +5 more
20070 citations
Semantic Scholar

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