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A. Lasek · SciRah

Researcher profile · Semantic Scholar

A. Lasek

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A. Lasek — researcher profile on SciRah

h-index: 29
Works: 90
Citations: 2,431

Most-cited papers

Expression profiling of primary non-small cell lung cancer for target identification
J. Heighway, T. Knapp, Lenetta Boyce, S. Brennand +7 more
2002Oncogene156 citations
Semantic Scholar
Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine.
A. Karpf, A. Lasek, T. O. Ririe, Adrianne N. Hanks +2 more
2004Molecular Pharmacology149 citations
Semantic Scholar
Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms.
A. Rothenfluh, Robert J Threlkeld, R. J. Bainton, L. Tsai +2 more
2006Cell132 citations Open access
Semantic Scholar
An Evolutionary Conserved Role for Anaplastic Lymphoma Kinase in Behavioral Responses to Ethanol
A. Lasek, Jana P. Lim, C. L. Kliethermes, Karen H. Berger +10 more
2011PLoS ONE99 citations Open access
Semantic Scholar
Ovarian Hormones Contribute to High Levels of Binge-Like Drinking by Female Mice
R. Satta, Elisa R. Hilderbrand, A. Lasek
2018Alcoholism: Clinical and Experimental Research92 citations Open access
Semantic Scholar
Estradiol increases the sensitivity of ventral tegmental area dopamine neurons to dopamine and ethanol
B. Vandegrift, Chang You, R. Satta, M. Brodie +1 more
2017PLoS ONE92 citations Open access
Semantic Scholar
Repeated Binge Drinking Increases Perineuronal Nets in the Insular Cortex
Hu Chen, D. He, A. Lasek
2015Alcoholism: Clinical and Experimental Research79 citations Open access
Semantic Scholar
Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice
A. Lasek, P. Janak, L. He, Jennifer L. Whistler +1 more
2007Genes, Brain and Behavior78 citations
Semantic Scholar
Perineuronal nets in the insula regulate aversion-resistant alcohol drinking
Hu Chen, A. Lasek
2018bioRxiv73 citations Open access
Semantic Scholar
Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents
R. Harris, M. Bajo, R. Bell, Y. Blednov +16 more
2016Journal of Neuroscience73 citations Open access
Semantic Scholar
Releasing Addiction Memories Trapped in Perineuronal Nets
A. Lasek, Hu Chen, Wei‐Yang Chen
2017Trends in Genetics63 citations Open access
Semantic Scholar
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
J. P. Bohnsack, Huai-Bo Zhang, Gabriela M Wandling, D. He +3 more
2022Science Advances60 citations Open access
Semantic Scholar
Effects of Ethanol on Brain Extracellular Matrix: Implications for Alcohol Use Disorder
A. Lasek
2016Alcoholism: Clinical and Experimental Research59 citations Open access
Semantic Scholar
Sex differences in cocaine conditioned place preference in C57BL/6J mice
Elisa R. Hilderbrand, A. Lasek
2014NeuroReport55 citations Open access
Semantic Scholar
The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Alleviates Depression-Like Behavior and Normalizes Epigenetic Changes in the Hippocampus During Ethanol Withdrawal
Wei‐Yang Chen, Huai-Bo Zhang, Eleonora Gatta, Elizabeth J. Glover +2 more
2019Alcohol54 citations Open access
Semantic Scholar
Drosophila, a genetic model system to study cocaine-related behaviors: A review with focus on LIM-only proteins
U. Heberlein, L. Tsai, D. Kapfhamer, A. Lasek
2008Neuropharmacology53 citations Open access
Semantic Scholar
Studying Sex Differences in Animal Models of Addiction: An Emphasis on Alcohol-Related Behaviors
Elisa R. Hilderbrand, A. Lasek
2017ACS Chemical Neuroscience51 citations Open access
Semantic Scholar
Estrogen Receptor α Regulates Ethanol Excitation of Ventral Tegmental Area Neurons and Binge Drinking in Female Mice
B. Vandegrift, Elisa R. Hilderbrand, R. Satta, Rex Tai +7 more
2019Journal of Neuroscience49 citations Open access
Semantic Scholar
Amygdala protein kinase C epsilon regulates corticotropin‐releasing factor and anxiety‐like behavior
H. Lesscher, T. McMahon, A. Lasek, Wen-Hai Chou +3 more
2008Genes, Brain and Behavior45 citations Open access
Semantic Scholar
Lmo Genes Regulate Behavioral Responses to Ethanol in Drosophila melanogaster and the Mouse
A. Lasek, Francesco Giorgetti, Karen H. Berger, Stacy Tayor +1 more
2011Alcoholism: Clinical and Experimental Research44 citations Open access
Semantic Scholar
Reducing alcohol drinking of alcohol-preferring (P) and high-alcohol drinking (HAD1) rats by targeting phosphodiesterase-4 (PDE4)
Kelle M. Franklin, S. R. Hauser, A. Lasek, J. McClintick +3 more
2015Psychopharmacology43 citations Open access
Semantic Scholar
Estrogen Receptor β in the Nucleus Accumbens Regulates the Rewarding Properties of Cocaine in Female Mice
R. Satta, B. Certa, D. He, A. Lasek
2017International Journal of Neuropsychopharmacology40 citations Open access
Semantic Scholar
The Small G Protein H-Ras In The Mesolimbic System Is A Molecular Gateway To Alcohol Seeking and Excessive Drinking Behaviors
S. Ben Hamida, J. Neasta, A. Lasek, Viktor N. Kharazia +4 more
2012Journal of Neuroscience37 citations Open access
Semantic Scholar
Alk Is a Transcriptional Target of LMO4 and ERα that Promotes Cocaine Sensitization and Reward
A. Lasek, Julie Gesch, Francesco Giorgetti, Viktor N. Kharazia +1 more
2011Journal of Neuroscience36 citations Open access
Semantic Scholar
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer
Yunlong Lu, Lauren M. Gutgesell, R. Xiong, Jiong Zhao +16 more
2019Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
Estradiol enhances ethanol reward in female mice through activation of ERα and ERβ
Elisa R. Hilderbrand, A. Lasek
2018Hormones and Behavior34 citations Open access
Semantic Scholar
Defining the role of corticotropin releasing factor binding protein in alcohol consumption
C. Haass-Koffler, Andrea Henry, G. Melkus, J. Simms +11 more
2016Translational Psychiatry34 citations Open access
Semantic Scholar
Anaplastic lymphoma kinase (ALK) regulates binge-like drinking and dopamine receptor sensitivity in the ventral tegmental area
John W. Dutton, Hu Chen, Chang You, M. Brodie +1 more
2016Addiction Biology34 citations Open access
Semantic Scholar
Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice
J. Truitt, Y. Blednov, Jillian M. Benavidez, Mendy Black +8 more
2016eNeuro32 citations Open access
Semantic Scholar
Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure
Wei‐Yang Chen, Hu Chen, Kana Hamada, Eleonora Gatta +8 more
2021Translational Psychiatry29 citations Open access
Semantic Scholar
Development of Inhibitors of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) as Candidates for CNS disorders
M. Pastor, Rosalía Fernández-Calle, Bruno Di Geronimo, Marta Vicente-Rodríguez +10 more
2017European journal of medicinal chemistry29 citations Open access
Semantic Scholar
Ethanol acts on KCNK13 potassium channels in the ventral tegmental area to increase firing rate and modulate binge–like drinking
Chang You, A. Savarese, B. Vandegrift, D. He +3 more
2018Neuropharmacology24 citations Open access
Semantic Scholar
Involvement of purinergic P2X4 receptors in alcohol intake of high-alcohol-drinking (HAD) rats
Kelle M. Franklin, S. R. Hauser, A. Lasek, R. Bell +1 more
2015Alcoholism: Clinical and Experimental Research24 citations Open access
Semantic Scholar
Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol
Rosalía Fernández-Calle, Marta Vicente-Rodríguez, M. Pastor, Esther Gramage +8 more
2018Neuropharmacology23 citations Open access
Semantic Scholar
Anaplastic Lymphoma Kinase Is a Regulator of Alcohol Consumption and Excitatory Synaptic Plasticity in the Nucleus Accumbens Shell
R. Mangieri, Esther Y. Maier, Tavanna R. Buske, A. Lasek +1 more
2017Frontiers in Pharmacology23 citations Open access
Semantic Scholar
Dependence-induced ethanol drinking and GABA neurotransmission are altered in Alk deficient mice
P. Schweitzer, C. Cates-Gatto, F. Varodayan, T. Nadav +3 more
2016Neuropharmacology23 citations Open access
Semantic Scholar
Knockdown of ventral tegmental area mu-opioid receptors in rats prevents effects of social defeat stress: Implications for amphetamine cross-sensitization, social avoidance, weight regulation and expression of brain-derived neurotrophic factor
Caitlin Johnston, Dan Herschel, A. Lasek, R. Hammer +1 more
2015Neuropharmacology22 citations Open access
Semantic Scholar
Ethanol activates Midkine and Anaplastic lymphoma kinase signaling in neuroblastoma cells and in the brain
D. He, Hu Chen, H. Muramatsu, A. Lasek
2015Journal of Neurochemistry21 citations Open access
Semantic Scholar
Sexually dimorphic role for insular perineuronal nets in aversion-resistant alcohol consumption
Luana Martins de Carvalho, Hu Chen, Mason Sutter, A. Lasek
2023Frontiers in Psychiatry20 citations Open access
Semantic Scholar
Epigenetic Mechanisms Underlying Stress-Induced Depression
L. D. de Carvalho, Wei‐Yang Chen, A. Lasek
2020International review of neurobiology20 citations Open access
Semantic Scholar
Lmo4 in the Basolateral Complex of the Amygdala Modulates Fear Learning
Rajani Maiya, Viktor N. Kharazia, A. Lasek, U. Heberlein
2012PLoS ONE19 citations Open access
Semantic Scholar
Estrogen modulates reward prediction errors and reinforcement learning
Carla E. M. Golden, Audrey C. Martin, Daljit Kaur, Andrew Mah +6 more
2025Nature Neuroscience18 citations Open access
Semantic Scholar
Estrogenic regulation of perineuronal nets in the mouse insular cortex and hippocampus
R. Nguyen, Razia Rahyab, A. Deshpande, E. Legge +5 more
2025Neuropharmacology17 citations
Semantic Scholar
Regulation of anxiety-like behavior and Crhr1 expression in the basolateral amygdala by LMO3
A. Savarese, A. Lasek
2018Psychoneuroendocrinology16 citations Open access
Semantic Scholar
Binge-Like Ethanol Drinking Activates ALK Signaling and Increases the Expression of STAT3 Target Genes in the Mouse Hippocampus and Prefrontal Cortex
Kana Hamada, Laura B. Ferguson, R. Mayfield, H. Krishnan +2 more
2021Genes, Brain and Behavior15 citations Open access
Semantic Scholar
Anaplastic Lymphoma Kinase Regulates Internalization of the Dopamine D2 Receptor
D. He, A. Lasek
2019Molecular Pharmacology14 citations Open access
Semantic Scholar
Multidimensional Top-Down Proteomics of Brain Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
Hae-Min Park, R. Satta, Roderick G Davis, Y. Goo +11 more
2019Journal of Proteome Research14 citations Open access
Semantic Scholar
Modulation of stress-, pain-, and alcohol-related behaviors by perineuronal nets
J. Aguilar, A. Lasek
2024Neurobiology of Stress13 citations Open access
Semantic Scholar
Receptor Tyrosine Kinases as Therapeutic Targets for Alcohol Use Disorder
Kana Hamada, A. Lasek
2019Neurotherapeutics13 citations Open access
Semantic Scholar
Midkine in the Mouse Ventral Tegmental Area Limits Ethanol Intake and Ccl2 Gene Expression
Hu Chen, D. He, A. Lasek
2017Genes, Brain and Behavior13 citations Open access
Semantic Scholar

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Hu Chen×10
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D. He×9
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U. Heberlein×7
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R. Satta×5
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Elisa R. Hilderbrand

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Chang You — researcher profile on SciRah

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Wei‐Yang Chen×4

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