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H. Zeng · SciRah

Researcher profile · Semantic Scholar

H. Zeng

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H. Zeng — researcher profile on SciRah

h-index: 28
Works: 77
Citations: 4,079

Most-cited papers

mTORC1 couples immune signals and metabolic programming to establish Treg cell function
H. Zeng, Kai Yang, Caryn M. Cloer, G. Neale +2 more
2013Nature766 citations Open access
Semantic Scholar
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic programming
Kai Yang, Sharad Shrestha, H. Zeng, Peer W. F. Karmaus +5 more
2013Immunity393 citations Open access
Semantic Scholar
mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
H. Zeng, Sivan Cohen, C. Guy, Sharad Shrestha +11 more
2016Immunity320 citations Open access
Semantic Scholar
Metabolism as a guiding force for immunity
Jonathan Jung, H. Zeng, Tiffany Horng
2019Nature Cell Biology304 citations
Semantic Scholar
Metabolic control of regulatory T cell development and function
H. Zeng, Hong-Bo Chi
2014Trends in immunology270 citations Open access
Semantic Scholar
Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation.
T. Yokosuka, Wakana Kobayashi, M. Takamatsu, K. Sakata-Sogawa +5 more
2010Immunity197 citations Open access
Semantic Scholar
mTOR signaling in the differentiation and function of regulatory and effector T cells
H. Zeng, Hong-Bo Chi
2017Current Opinion in Immunology176 citations Open access
Semantic Scholar
mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis
Nicole M. Chapman, H. Zeng, Thanh-Long M. Nguyen, Yan-Yan Wang +6 more
2018Nature Communications175 citations Open access
Semantic Scholar
Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells.
Xiao-Peng Wu, H. Zeng, Xianming Zhang, Ying-Yue Zhao +5 more
2004American Journal of Pathology167 citations Open access
Semantic Scholar
Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
2007Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
mTOR and lymphocyte cell metabolism
H. Zeng, Hong-Bo Chi
2013Current Opinion in Immunology97 citations Open access
Semantic Scholar
Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells
Yan-Yan Wang, Gong-Hua Huang, H. Zeng, Kai Yang +2 more
2013Proceedings of the National Academy of Sciences of the United States of America89 citations Open access
Semantic Scholar
Homeostasis and transitional activation of regulatory T cells require c-Myc
J. Saravia, H. Zeng, Yogesh Dhungana, Daniel Bastardo Blanco +10 more
2020Science Advances82 citations Open access
Semantic Scholar
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis
Zeng-Di Zhang, Zan Huang, B. Ong, Chinmayi Sahu +2 more
2019Haematologica62 citations Open access
Semantic Scholar
Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity
Xian Zhou, Xingxing Zhu, Chao-Fan Li, Yan-Feng Li +7 more
2020bioRxiv58 citations Open access
Semantic Scholar
Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector Treg cells
Wei Su, Nicole M. Chapman, Jun Wei, H. Zeng +9 more
2020Cell Metabolism54 citations Open access
Semantic Scholar
mTOR and metabolic regulation of conventional and regulatory T cells
Chao-Hong Liu, Nicole M. Chapman, Peer W. F. Karmaus, H. Zeng +1 more
2015Journal of Leukocyte Biology52 citations Open access
Semantic Scholar
Fatty acid metabolism in adaptive immunity
Xian Zhou, Xingxing Zhu, H. Zeng
2021The FEBS Journal49 citations Open access
Semantic Scholar
Bcl10 Plays a Divergent Role in NK Cell-Mediated Cytotoxicity and Cytokine Generation1
Subramaniam Malarkannan, J. Regunathan, Hai-Yan Chu, Snježana Kutleša +4 more
2007Journal of Immunology49 citations
Semantic Scholar
PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development
Mei Yu, Yu-Hong Chen, H. Zeng, Yongwei Zheng +11 more
2017Nature Communications45 citations Open access
Semantic Scholar
Nuclear Export of the NF-κB Inhibitor IκBα Is Required for Proper B Cell and Secondary Lymphoid Tissue Formation
S. Wuerzberger-Davis, Yu-Hong Chen, David T. Yang, J. Kearns +11 more
2011Immunity45 citations Open access
Semantic Scholar
mTOR signaling in immune cells and its implications for cancer immunotherapy.
H. Zeng
2017Cancer Letters44 citations
Semantic Scholar
Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7–driven B lymphopoiesis
H. Zeng, Mei Yu, Hai-Yan Tan, Yuxin Li +9 more
2018Science Advances41 citations Open access
Semantic Scholar
The interplay between regulatory T cells and metabolism in immune regulation
H. Zeng, Hong-Bo Chi
2013Oncoimmunology40 citations Open access
Semantic Scholar
Phosphorylation of Bcl10 Negatively Regulates T-Cell Receptor-Mediated NF-κB Activation
H. Zeng, Lie Di, Guoping Fu, Yu-Hong Chen +4 more
2007Molecular and Cellular Biology39 citations Open access
Semantic Scholar
Essential Role of Phospholipase Cγ2 in Early B-Cell Development and Myc-Mediated Lymphomagenesis
R. Wen, Yu-Hong Chen, L. Bai, Guoping Fu +7 more
2006Molecular and Cellular Biology36 citations Open access
Semantic Scholar
Antigen Specific Humoral and Cellular Immunity Following SARS-CoV-2 Vaccination in ANCA-Associated Vasculitis Patients Receiving B-Cell Depleting Therapy
P. Marty, V. V. Van Keulen, C. Erskine, Maleeha Shah +13 more
2022Frontiers in Immunology29 citations Open access
Semantic Scholar
Alternative 3' UTR polyadenylation of Bzw1 transcripts display differential translation efficiency and tissue-specific expression.
Mingyan Yu, Hai-Bo Sha, Yan Gao, H. Zeng +2 more
2006Biochemical and Biophysical Research Communications - BBRC29 citations
Semantic Scholar
mTOR signaling and transcriptional regulation in T lymphocytes
H. Zeng, Hong-Bo Chi
2014Transcription28 citations Open access
Semantic Scholar
B Cell Lymphoma 10 Is Essential for FcεR-Mediated Degranulation and IL-6 Production in Mast Cells1
Yu-Hong Chen, B. Pappu, H. Zeng, L. Xue +4 more
2007Journal of Immunology27 citations Open access
Semantic Scholar
HNRNPH1 is required for rhabdomyosarcoma cell growth and survival
Yan-Feng Li, J. Bakke, David B. Finkelstein, H. Zeng +2 more
2018Oncogenesis24 citations Open access
Semantic Scholar
mTOR signaling and transcriptional regulation in T lymphocytes.
H. Zeng, Hong-Bo Chi
2014Transcription21 citations
Semantic Scholar
Immune checkpoint inhibitor-induced inflammatory arthritis: a novel clinical entity with striking similarities to seronegative rheumatoid arthritis
Yuan Liu, J. Jaquith, K. Mccarthy-Fruin, Xingxing Zhu +6 more
2020Clinical Rheumatology19 citations
Semantic Scholar
Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes
L. Shi, J. Saravia, H. Zeng, N. Kalupahana +3 more
2016Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Patients with ACPA-positive and ACPA-negative rheumatoid arthritis show different serological autoantibody repertoires and autoantibody associations with disease activity
Kevin Y. Cunningham, B. Hur, Vijay K. Gupta, C. Arment +14 more
2022Scientific Reports16 citations Open access
Semantic Scholar
Mevalonate metabolism–dependent protein geranylgeranylation regulates thymocyte egress
Xing-Rong Du, H. Zeng, Shao-Feng Liu, C. Guy +4 more
2019Journal of Experimental Medicine15 citations Open access
Semantic Scholar
T Cell Receptor-mediated Activation of CD4+CD44hi T Cells Bypasses Bcl10
H. Zeng, Yu-Hong Chen, Mei Yu, L. Xue +4 more
2008Journal of Biological Chemistry14 citations Open access
Semantic Scholar
A novel humanized PD-1/PD-L1 mouse model permits direct comparison of antitumor immunity generated by FDA-approved PD-1 and PD-L1 inhibitors
Whitney Barham, Michelle A. Hsu, Xin Liu, S. Harrington +8 more
2023ImmunoHorizons12 citations Open access
Semantic Scholar
B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells.
Yu-Hong Chen, B. Pappu, H. Zeng, L. Xue +4 more
2007Journal of Immunology12 citations
Semantic Scholar
Atomic Force Microscopy Studies on DNA Structural Changes Induced by Vincristine Sulfate and Aspirin
Yi Zhu, H. Zeng, Jian-Ming Xie, Long Ba +2 more
2004Microscopy and Microanalysis12 citations
Semantic Scholar
Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
Drew Wilfahrt, Rachael L. Philips, J. Lama, M. Kizerwetter +6 more
2021eLife11 citations Open access
Semantic Scholar
mTORC2 contributes to systemic autoimmunity
Xian Zhou, Haiyu Qi, Meilu Li, Yan-Feng Li +6 more
2022Immunology10 citations Open access
Semantic Scholar
Immune responses and disease biomarker long-term changes following COVID-19 mRNA vaccination in a cohort of rheumatic disease patients
Ze-Sheng An, Gabriel Figueroa-Parra, Xian Zhou, Yan-Feng Li +12 more
2023Frontiers in Immunology8 citations Open access
Semantic Scholar
The role of Raptor in lymphocytes differentiation and function
Jianing Tang, Lu Yang, Fei Guan, Heather Miller +11 more
2023Frontiers in Immunology8 citations Open access
Semantic Scholar
Bcl 10 plays a critical role in NF-B activation induced by G protein-coupled receptors
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
20077 citations
Semantic Scholar
Erratum: Bcl10 plays a critical role in NF-κB activation induced by G protein-coupled receptors (Proceedings of the National Academy of Sciences of the United States of America (January 2, 2007) 1, 104, (145-150) DOI: 10.1073/pnas.0601894104)
Donghai Wang, Y. You, Pei-Chun Lin, L. Xue +4 more
20073 citations Open access
Semantic Scholar
Mutation in the first Ig-like domain of Kit leads to JAK2 activation and myeloproliferation in mice.
Zan Huang, Hai-Bin Ruan, Zeng-Di Zhang, Wei-Qian Chen +3 more
2014American Journal of Pathology2 citations Open access
Semantic Scholar
Resilient CD8+ T cells maintain a high cytotoxic capacity by balancing ROS via ME1 upregulation
J. Gicobi, Zhiming Mao, Grace DeFranco, Ying Li +23 more
2022bioRxiv1 citations Open access
Semantic Scholar
Metabolic sleuthing solves a rare immunodeficiency disease
H. Zeng, Hong-Bo Chi
2019Nature Immunology1 citations
Semantic Scholar
A cytokine duet regulates inflammatory bowel disease
H. Zeng
2018Science Translational Medicine1 citations
Semantic Scholar

Frequent co-authors

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De-Min Wang — researcher profile on SciRah

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Xin Lin — researcher profile on SciRah

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C. Guy — researcher profile on SciRah

Yogesh Dhungana×5

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Yogesh Dhungana — researcher profile on SciRah