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M. Kuziora · SciRah

Researcher profile · Semantic Scholar

M. Kuziora

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M. Kuziora — researcher profile on SciRah

h-index: 11
Works: 32
Citations: 1,181

Most-cited papers

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
Daniel K. Wells, M. Buuren, Kristen K. Dang, Vanessa M. Hubbard-Lucey +141 more
2020Cell495 citations Open access
Semantic Scholar
Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab
R. Raja, M. Kuziora, Philip Z. Brohawn, B. Higgs +3 more
2018Clinical Cancer Research224 citations Open access
Semantic Scholar
A Blood-based Assay for Assessment of Tumor Mutational Burden in First-line Metastatic NSCLC Treatment: Results from the MYSTIC Study
H. Si, M. Kuziora, K. Quinn, E. Helman +11 more
2020Clinical Cancer Research94 citations
Semantic Scholar
Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis
K. Steele, Tze-Heng Tan, R. Korn, Karma Dacosta +12 more
2018Journal of Immunotherapy for Cancer87 citations Open access
Semantic Scholar
OA04.07 Mutations Associated with Sensitivity or Resistance to Immunotherapy in mNSCLC: Analysis from the MYSTIC Trial
N. Rizvi, B. Cho, N. Reinmuth, K. Lee +12 more
2019Journal of Thoracic Oncology54 citations Open access
Semantic Scholar
Baseline Plasma Cell Gene Signature Predicts Improvement in Systemic Sclerosis Skin Scores Following Treatment With Inebilizumab (MEDI‐551) and Correlates With Disease Activity in Systemic Lupus Erythematosus and Chronic Obstructive Pulmonary Disease
K. Streicher, S. Sridhar, M. Kuziora, C. Morehouse +7 more
2018Arthritis & Rheumatology40 citations
Semantic Scholar
Inhibition of mast cells: a novel mechanism by which nintedanib may elicit anti-fibrotic effects
C. Overed-Sayer, Elena Miranda, R. Dunmore, Elena Liarte Marin +12 more
2020Thorax39 citations Open access
Semantic Scholar
Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis
Xiang Guo, B. Higgs, A. Bay-Jensen, Yu-Ling Wu +7 more
2018Rheumatology37 citations
Semantic Scholar
HERC5 is a prognostic biomarker for post-liver transplant recurrent human hepatocellular carcinoma
Feng Xue, B. Higgs, Jiaqi Huang, C. Morehouse +15 more
2015Journal of Translational Medicine32 citations Open access
Semantic Scholar
Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation CD 4 + T-Cell Profiles and Peripheral Blood Ex-Vivo Responses to T-Cell Directed Stimulation Delineate COPD Phenotypes
M. Roberts, B. Higgs, P. Brohawn, F. Pilataxi +4 more
201512 citations
Semantic Scholar
Biologic and clinical relevance of an IFNG mRNA signature (IFNGS) and PD-L1 protein expression in tumor and immune cells in urothelial cancer (UC) patients (pts) treated with durvalumab (D).
C. Bais, M. Kuziora, C. Morehouse, B. Higgs +12 more
201711 citations
Semantic Scholar
Association of early reduction in circulating tumor DNA (ctDNA) with improved progression-free survival (PFS) and overall survival (OS) of patients (pts) with urothelial bladder cancer (UBC) treated with durvalumab (D).
M. Kuziora, B. Higgs, Philip Z. Brohawn, R. Raja +2 more
201711 citations
Semantic Scholar
BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data
Wei Zhu, M. Kuziora, T. Creasy, Z. Lai +10 more
2015Nucleic Acids Research11 citations Open access
Semantic Scholar
A Randomized Phase 2 Study of MEDI0680 in Combination With Durvalumab Versus Nivolumab Monotherapy in Patients With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
M. Voss, A. Azad, A. Hansen, J. Gray +9 more
2022Clinical Cancer Research10 citations Open access
Semantic Scholar
Abstract 582: Circulating tumor DNA (ctDNA) variant allele frequencies are reduced in responders to durvalumab and low baseline variant allele frequencies are associated with improved overall survival in NSCLC patients
M. Kuziora, B. Higgs, Philip Z. Brohawn, R. Raja +1 more
20177 citations
Semantic Scholar
Gene expression analysis of tumor biopsies from a trial of durvalumab to identify subsets of NSCLC with shared immune pathways.
K. Streicher, C. Morehouse, Y. Sebastian, M. Kuziora +2 more
20175 citations
Semantic Scholar
Abstract 2299: Misclassification of clonal hematopoietic mutations as tumor-derived confound accurate ctDNA-response assessment in patients with metastatic non-small-cell lung cancer: analyses from the phase 3 MYSTIC trial
C. Abbosh, M. Kuziora, D. Stetson, Z. Lai +9 more
2023Cancer Research4 citations
Semantic Scholar
Effect of tralokinumab on serum periostin and IgE levels in uncontrolled severe asthma
K. Ranade, S. Manetz, M. Liang, Rozanne Lee +3 more
20154 citations
Semantic Scholar
Integrating Genomics into Drug Discovery and Development: Challenges and Aspirations
R. Raja, Young S. Lee, K. Streicher, James Conway +9 more
2017Pharmaceutical Medicine3 citations
Semantic Scholar
A plasma-based assay for assessment of tumour mutational burden in patients with metastatic non-small cell lung cancer in the first-line treatment setting: Results from the MYSTIC study
H. Si, M. Kuziora, E. Helman, K. Quinn +4 more
2019European Journal of Cancer2 citations
Semantic Scholar
Early reduction in circulating tumor DNA (ctDNA) and survival in gastric cancer patients (pts) treated with durvalumab (D), tremelimumab (T), or durvalumab in combination with tremelimumab (D+T).
Philip Z. Brohawn, B. Higgs, M. Kuziora, J. Englert +1 more
20182 citations
Semantic Scholar
1264P Early circulating tumour DNA (ctDNA) dynamics for predicting and monitoring response to immunotherapy (IO) vs chemotherapy (CT) in patients with 1L metastatic (m) NSCLC: Analyses from the phase III MYSTIC trial
S. Peters, N. Rizvi, M. Kuziora, Z. Lai +8 more
2021Annals of Oncology1 citations Open access
Semantic Scholar
Dipeptidyl peptidase-4 (DPP-4) may predict response to tralokinumab in patients with asthma
K. Ranade, M. Kuziora, Tuyet-Hang Pham, G. Damera +10 more
20161 citations
Semantic Scholar
Abstract 3197: Blockade of regulatory signaling pathways reduces immunosuppression in the PDAC tumor microenvironment
L. Greenlees, Li Cheng, Bilal Omar, Yelena Lazdun +6 more
2022Cancer Research0 citations
Semantic Scholar
Mutationen sind assoziiert mit einer Sensitivität oder Resistenz gegenüber einer Immuntherapie beim metastasierten NSCLC: eine Analyse aus der MYSTIC-Studie
A. Rittmeyer, N. Rizvi, B. Cho, K. Lee +13 more
2020Pneumologie0 citations
Semantic Scholar
Abstract B55: Exploratory biomarker analyses of tumor and peripheral blood samples from the phase I durvalumab plus gefitinib trial in EGFR-mutated NSCLC
Tammie C. Yeh, H. Angell, V. Rowlands, E. V. Jones +10 more
20200 citations
Semantic Scholar
Abstract 693: Deep learning analysis of circulating tumor DNA identified a pan-tumor molecular subtype with enhanced response to durvalumab (anti-PDL1)
Song Wu, S. Sridhar, H. Si, M. Kuziora +7 more
2019Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
IFNγ mRNA signature (IFNγ sig), circulating tumor DNA (ctDNA), and survival in NSCLC or urothelial cancer (UC) treated with durvalumab (D).
B. Higgs, C. Morehouse, M. Kuziora, Philip Z. Brohawn +5 more
20180 citations
Semantic Scholar
Abstract 5390: microRNA signature of T cell exhaustion
L. Greenlees, M. Kuziora, Y. Sebastian, T. Creasy +7 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Integrating Genomics into Drug Discovery and Development: Challenges and Aspirations
R. Raja, Y. S. Lee, K. Streicher, James Conway +9 more
2017Pharmaceutical Medicine0 citations
Semantic Scholar
Abstract 4851: BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality in somatic mosaicism using copy number ratio and allele frequency
Wei Zhu, M. Kuziora, C. Morehouse, Tian-wei Zhang +10 more
20150 citations
Semantic Scholar
A microRNA Signature Predicts Response to Anti-CD19 Therapy (MEDI-551) in B-Cell Malignancies
K. Streicher, Philip Z. Brohawn, M. Kuziora, F. Pilataxi +7 more
20140 citations
Semantic Scholar

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