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Yu-Ling Wu · SciRah

Researcher profile · Semantic Scholar

Yu-Ling Wu

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Yu-Ling Wu — researcher profile on SciRah

h-index: 20
Works: 42
Citations: 1,347

Most-cited papers

Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults
Xiang-Qing Yu, G. Robbie, Yu-Ling Wu, Mark T. Esser +5 more
2016Antimicrobial Agents and Chemotherapy129 citations Open access
Semantic Scholar
First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors
J. Bendell, P. Lorusso, M. Overman, A. Noonan +20 more
2023Cancer Immunology and Immunotherapy122 citations Open access
Semantic Scholar
Wnt/β‐Catenin Signaling Pathway Upregulates c‐Myc Expression to Promote Cell Proliferation of P19 Teratocarcinoma Cells
Shuai Zhang, Yi Li, Yu-Ling Wu, K. Shi +2 more
2012The Anatomical Record100 citations Open access
Semantic Scholar
Pharmacokinetics of Anti-hepcidin Monoclonal Antibody Ab 12B9m and Hepcidin in Cynomolgus Monkeys
Jim J. Xiao, W. Krzyzanski, Yow-Ming C. Wang, Hong-Yan Li +5 more
2010AAPS Journal84 citations Open access
Semantic Scholar
Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial.
B. François, H. Jafri, J. Chastre, M. Sánchez-García +27 more
2021Lancet. Infectious Diseases (Print)77 citations Open access
Semantic Scholar
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients: a randomised controlled trial
J. Chastre, B. François, M. Bourgeois, A. Komnos +34 more
2022Critical Care73 citations Open access
Semantic Scholar
Submicron Size Particles of a Murine Monoclonal Antibody Are More Immunogenic Than Soluble Oligomers or Micron Size Particles Upon Subcutaneous Administration in Mice.
G. Kijanka, Jared S. Bee, Samuel Korman, Yu-Ling Wu +4 more
2018Journal of Pharmacy and Science70 citations Open access
Semantic Scholar
Safety, efficacy and pharmacodynamics (PD) of MEDI9447 (oleclumab) alone or in combination with durvalumab in advanced colorectal cancer (CRC) or pancreatic cancer (panc).
M. Overman, P. LoRusso, J. Strickler, S. Patel +15 more
201862 citations
Semantic Scholar
Drug Target Interference in Immunogenicity Assays: Recommendations and Mitigation Strategies
Z. Zhong, A. Clements-Egan, B. Gorovits, M. Maia +4 more
2017AAPS Journal61 citations Open access
Semantic Scholar
Application of multi-factorial design of experiments to successfully optimize immunoassays for robust measurements of therapeutic proteins.
C. Ray, Vimal Patel, Judy Y Shih, Chris R Macaraeg +5 more
2009Journal of Pharmaceutical and Biomedical Analysis52 citations
Semantic Scholar
Characterization of Alpha-Toxin hla Gene Variants, Alpha-Toxin Expression Levels, and Levels of Antibody to Alpha-Toxin in Hemodialysis and Postsurgical Patients with Staphylococcus aureus Bacteremia
B. Sharma-Kuinkel, Yu-Ling Wu, D. Tabor, Ho-Yin S. Mok +13 more
2014Journal of Clinical Microbiology51 citations Open access
Semantic Scholar
Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893
D. Tabor, Li Yu, Ho-Yin S. Mok, C. Tkaczyk +8 more
2016Antimicrobial Agents and Chemotherapy48 citations Open access
Semantic Scholar
Safety and clinical activity of intratumoral MEDI9197 alone and in combination with durvalumab and/or palliative radiation therapy in patients with advanced solid tumors
L. Siu, J. Brody, Shilpa Gupta, A. Marabelle +15 more
2020Journal for ImmunoTherapy of Cancer41 citations Open access
Semantic Scholar
Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis
Xiang Guo, B. Higgs, A. Bay-Jensen, Yu-Ling Wu +7 more
2018Rheumatology37 citations
Semantic Scholar
Sensitive Colorimetric Detection of Interleukin-6 via Lateral Flow Assay Incorporated Silver Amplification Method
M. Rahbar, Yu-Ling Wu, J. Subramony, Guo-Zhen Liu
2021Frontiers in Bioengineering and Biotechnology35 citations Open access
Semantic Scholar
Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development.
Masood U. Khan, R. Bowsher, M. Cameron, V. Devanarayan +9 more
2015Bioanalysis35 citations
Semantic Scholar
Neutralizing Antibody Validation Testing and Reporting Harmonization
H. Myler, J. Pedras-Vasconcelos, T. Lester, F. Civoli +42 more
2023AAPS Journal27 citations Open access
Semantic Scholar
Characterisation of anti‐alpha toxin antibody levels and colonisation status after administration of an investigational human monoclonal antibody, MEDI4893, against Staphylococcus aureus alpha toxin
A. Ruzin, Yu-Ling Wu, Li Yu, Xiang-Qing Yu +8 more
2018Clinical & Translational Immunology27 citations Open access
Semantic Scholar
Correlation of screening and confirmatory results in tiered immunogenicity testing by solution-phase bridging assays.
R. Kubiak, Lan-Ju Zhang, Jian-Chun Zhang, Yuan Zhu +13 more
2013Journal of Pharmaceutical and Biomedical Analysis27 citations
Semantic Scholar
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies
A. Dippel, Austin Gallegos, V. Aleti, Arnita S. Barnes +28 more
2022mAbs21 citations Open access
Semantic Scholar
Prevalence of IgG and Neutralizing Antibodies against Staphylococcus aureus Alpha-Toxin in Healthy Human Subjects and Diverse Patient Populations
Yu-Ling Wu, Xu Liu, Ahmad Akhgar, Jia J. Li +6 more
2017Infection and Immunity21 citations Open access
Semantic Scholar
Tartrate-resistant acid phosphatase (TRACP 5b): a biomarker of bone resorption rate in support of drug development: modification, validation and application of the BoneTRAP kit assay.
Yu-Ling Wu, Jean W. Lee, Lennie Uy, Bassam Abosaleem +3 more
2009Journal of Pharmaceutical and Biomedical Analysis19 citations
Semantic Scholar
An electrochemiluminescence (ECL)-based assay for the specific detection of anti-drug antibodies of the IgE isotype.
Yu-Ling Wu, Xu Liu, Yan Chen, Robert M. Woods +5 more
2013Journal of Pharmaceutical and Biomedical Analysis17 citations
Semantic Scholar
Abstract CT091: Safety and pharmacodynamic activity of MEDI9197, a TLR 7/8 agonist, administered intratumorally in subjects with solid tumors
Shilpa Gupta, J. Grilley-Olson, D. Hong, A. Marabelle +13 more
2017Clinical Trials15 citations
Semantic Scholar
Pharmacological profile of MEDI-551, a novel anti-CD19 antibody, in human CD19 transgenic mice.
S. Gallagher, S. Turman, I. Yusuf, Ahmad Akhgar +4 more
2016International Immunopharmacology15 citations
Semantic Scholar
A Neutralizing Antibody Assay Based on a Reporter of Antibody-Dependent Cell-Mediated Cytotoxicity
Yu-Ling Wu, Jia J. Li, Hyun Jun Kim, Xu Liu +7 more
2015AAPS Journal15 citations Open access
Semantic Scholar
Enhanced Pharmacokinetic Bioanalysis of Antibody–drug Conjugates using Hybrid Immunoaffinity Capture and Microflow LC-MS/MS
Moo-jin Suh, Joshua B. Powers, C. Daniels, Yu-Ling Wu
2023AAPS Journal14 citations
Semantic Scholar
Monoclonal Antibody Dimers Induced by Low pH, Heat, or Light Exposure Are Not Immunogenic Upon Subcutaneous Administration in a Mouse Model.
G. Kijanka, Jared S. Bee, M. Schenerman, Samuel Korman +3 more
2019Journal of Pharmacy and Science14 citations Open access
Semantic Scholar
Abstract 1538: Levels and enzyme activity of CD73 in primary samples from cancer patients
Qi-Hui Huang, N. Durham, Erin Sult, Yu-Ling Wu +8 more
201513 citations
Semantic Scholar
Selection of a Ligand-Binding Neutralizing Antibody Assay for Benralizumab: Comparison with an Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) Cell-Based Assay
Yu-Ling Wu, Ahmad Akhgar, Jia J. Li, Bin-Bing Yu +4 more
2018AAPS Journal11 citations Open access
Semantic Scholar
Tezepelumab decreases matrix remodelling and inflammatory pathways in patients with asthma
S. Sridhar, Wei Zhao, Tuyet-Hang Pham, J. Kearley +5 more
2019Airway pharmacology and treatment10 citations
Semantic Scholar
2839. Efficacy, Pharmacokinetics (PK), and Safety Profile of Suvratoxumab (MEDI4893), a Staphylococcus aureus Alpha Toxin (AT)-Neutralizing Human Monoclonal Antibody in Mechanically Ventilated Patients in Intensive Care Units; Results of the Phase 2 SAATELLITE Study Conducted by the Public-Private C
B. François, M. S. Sánchez García, P. Eggimann, P. Dequin +18 more
2019Open Forum Infectious Diseases5 citations Open access
Semantic Scholar
ATG13 is involved in immune response of pathogen invasion in blood clam Tegillarca granosa
Yu-Ling Wu, Guosheng Liu, Zengpeng Li, Ming-Liang Chen +1 more
2023Frontiers in Veterinary Science3 citations Open access
Semantic Scholar
Fit‐for‐Purpose Method Validation and Assays for Biomarker Characterization to Support Drug Development
Jean W. Lee, Yu-Ling Wu, Jin Wang
2010Biomarkers in Drug Discovery and Development2 citations
Semantic Scholar
Abstract A37: Evaluation of eDHFR/iTag PET reporter gene immunogenicity and application in GPC3 CAR T cells
M. Sellmyer, Iris K. Lee, Kyle K. Kuszpit, Jyoti Roy +13 more
2022Cancer immunology research1 citations
Semantic Scholar
Preclinical Characterization of an Antibody–Drug Conjugate Targeting CS-1 and the Identification of Uncharacterized Populations of CS-1–Positive Cells
Ruo-Yan Chen, Saravanan Rajan, Michael G. Overstreet, Elaine M. Hurt +17 more
2020Molecular Cancer Therapeutics0 citations Open access
Semantic Scholar
1557. Population Pharmacokinetics of Suvratoxumab (MEDI4893), an Extended Half-life Staphylococcus aureus Alpha Toxin-Neutralizing Human Monoclonal Antibody, in Healthy Adults and Patients on Mechanical Ventilation in Intensive Care Units
V. Pierre, B. François, M. Hernandez‐Illas, M. S. Sánchez García +19 more
2019Open Forum Infectious Diseases0 citations Open access
Semantic Scholar
Staphylococcus aureus Alpha Toxin Expression is Highly Conserved in MSSA and MRSA Hospital Respiratory Isolates Collected from an International Surveillance Study
D. Tabor, Li Yu, Ho-Yin S. Mok, Bret R. Sellman +8 more
20150 citations Open access
Semantic Scholar
Abstract 2425: Nucleosomal DNA assay development and utility as PoP biomarker.
Xiao-Qing Shi, Hai-Feng Bao, Yu-Ling Wu, Xiao-Ru Chen +3 more
20130 citations
Semantic Scholar
Wnt／β-catenin信号通路在胚胎癌细胞增殖中作用及机制研究
Shuai Zhang, Yi Li, Yu-Ling Wu, K. Shi +2 more
20110 citations
Semantic Scholar
EXPRESSIONS OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 IN MOUSE ENDOMETRIUM DURING EARLY PREGNANCY
Yu-Ling Wu
20080 citations
Semantic Scholar
Effect of calcitonin on development and differentiation of mouse blastocyst {\sl in vitro}
Fuwu Wang, Yu-Ling Wu, Shang-Ming Liu, Xiao-Li Zhang +3 more
20050 citations
Semantic Scholar

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Mark T. Esser×9
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A. Ruzin×6
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Ho-Yin S. Mok×5

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