Researcher profile · Semantic Scholar

Guoping Fu

h-index: 15
Works: 39
Citations: 934

Most-cited papers

Isolation of Methyl Parathion-Degrading Strain M6 and Cloning of the Methyl Parathion Hydrolase Gene
Cui Zhongli, Shun-Peng Li, Guoping Fu
2001Applied and Environmental Microbiology272 citations Open access
Semantic Scholar
Phospholipase Cγ1 is essential for T cell development, activation, and tolerance
Guoping Fu, Yu-Hong Chen, Mei Yu, Andrew Podd +10 more
2010Journal of Experimental Medicine111 citations Open access
Semantic Scholar
CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance
Yu-Hong Chen, Mei Yu, Yongwei Zheng, Guoping Fu +11 more
2019Nature Communications80 citations Open access
Semantic Scholar
Expression, purification, and characterization of a novel methyl parathion hydrolase.
Guoping Fu, Z. Cui, Ting-Ting Huang, Shun-Peng Li
2004Protein Expression and Purification57 citations
Semantic Scholar
An important role of phospholipase Cγ1 in pre‐B‐cell development and allelic exclusion
R. Wen, Yu-Hong Chen, James Schuman, Guoping Fu +4 more
2004EMBO Journal47 citations Open access
Semantic Scholar
PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development
Mei Yu, Yu-Hong Chen, H. Zeng, Yongwei Zheng +11 more
2017Nature Communications45 citations Open access
Semantic Scholar
Phosphorylation of Bcl10 Negatively Regulates T-Cell Receptor-Mediated NF-κB Activation
H. Zeng, Lie Di, Guoping Fu, Yu-Hong Chen +4 more
2007Molecular and Cellular Biology39 citations Open access
Semantic Scholar
Essential Role of Phospholipase Cγ2 in Early B-Cell Development and Myc-Mediated Lymphomagenesis
R. Wen, Yu-Hong Chen, L. Bai, Guoping Fu +7 more
2006Molecular and Cellular Biology36 citations Open access
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Phospholipase Cγ2 plays a role in T-cell receptor signal transduction and T-cell selection
Guoping Fu, Yu-Hong Chen, James Schuman, De-Min Wang +1 more
2012Journal of Immunology34 citations Open access
Semantic Scholar
Phospholipase Cγ2 Mediates RANKL-stimulated Lymph Node Organogenesis and Osteoclastogenesis*
Ya-Bing Chen, Xiao-Hong Wang, Lie Di, Guoping Fu +12 more
2008Journal of Biological Chemistry28 citations Open access
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Kras is critical for B cell lymphopoiesis
Yu-Hong Chen, Yongwei Zheng, Xiaona You, Mei Yu +8 more
2016Journal of Immunology27 citations Open access
Semantic Scholar
The adhesion molecule PECAM-1 enhances the TGFβ-mediated inhibition of T cell function
D. Newman, Guoping Fu, Tamara Adams, W. Cui +3 more
2016Science Signaling26 citations Open access
Semantic Scholar
Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells
D. Newman, Guoping Fu, L. McOlash, David M. Schauder +6 more
2018Journal of Leukocyte Biology21 citations Open access
Semantic Scholar
Critical role of Bcl10 in BAFF-regulated NF-κB activation and survival of anergic B cells
Mei Yu, Yu-Hong Chen, Yinghong He, Andrew Podd +6 more
2012Journal of Immunology17 citations Open access
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Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation
Zhengqi Wang, Tamisha Y. Vaughan, Wandi Zhu, Yu-Hong Chen +10 more
2019Frontiers in Immunology15 citations Open access
Semantic Scholar
Exosomes from human urine-derived stem cells carry NRF1 to alleviate bladder fibrosis via regulating miR-301b-3p/TGFβR1 pathway
Jun-Wei Wu, Xin-Xin Wang, Guoping Fu, Yiyuan Feng +8 more
2022Molecular and Cellular Biochemistry10 citations
Semantic Scholar
A lineage-specific requirement for YY1 polycomb group protein function in early T cell development.
Anna L. F. V. Assumpcao, Guoping Fu, Deependra K Singh, Zhanping Lu +5 more
2021Development10 citations Open access
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Generation of PECAM-1 (CD31) Conditional Knockout Mice
Huiying Zhi, T. Kanaji, Guoping Fu, D. Newman +1 more
2019Genesis9 citations Open access
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Phospholipase Cγ1 is required for pre-TCR signal transduction and pre-T cell development
Guoping Fu, Mei Yu, Yu-Hong Chen, Yongwei Zheng +4 more
2016European Journal of Immunology9 citations Open access
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Deep phosphotyrosine characterisation of primary murine T cells using Broad Spectrum Optimisation of Selective Triggering
Aurora Callahan, Yu-Chua Xien, Alijah A Griffith, T. Hildebrandt +4 more
2024Proteomics8 citations Open access
Semantic Scholar
Kras-deficient T cells attenuate graft-versus-host disease but retain graft-versus-leukemia activity
Lan Luo, Yu-Hong Chen, Xiao Chen, Yongwei Zheng +13 more
2020Journal of Immunology7 citations Open access
Semantic Scholar
A Lineage-Specific Requirement for YY1 Polycomb Group Protein Function in Early T Cell Development
Anna Luiza Facchetti Vinhaes Assumpcao, Guoping Fu, Zhanping Lu, Ashley Kuehnl +2 more
20206 citations Open access
Semantic Scholar
Cloned antibodies from patients with heparin-induced thrombocytopenia (HIT) provide new clues to HIT pathogenesis.
Wen Zhu, Yongwei Zheng, Mei Yu, Yaling Wu +10 more
2022Blood4 citations Open access
Semantic Scholar
Evaluation of nestin or osterix promoter-driven cre/loxp system in studying the biological functions of murine osteoblastic cells.
Xin-Lin Su, Mei Yu, G. Qiu, Yongwei Zheng +10 more
2016American journal of translational research4 citations
Semantic Scholar
CARD 19, a novel regulator of the TAK1/NF-κB pathway in self-reactive B cells
Yongwei Zheng, Mei Yu, Yu-Hong Chen, L. Xue +5 more
2023Journal of Immunology3 citations Open access
Semantic Scholar
Massive Cerebral Air Embolism With Very Early Cortical Laminar Necrosis.
Lingjia Xu, Li Ma, Guoping Fu
2022Stroke2 citations Open access
Semantic Scholar
Novel role of platelet endothelial cell adhesion molecule-1 (PECAM-1) in facilitating TGF-beta-mediated inhibition of T cell function
D. Newman, Tamara Adams, V. Arumugam, Theresa Bluemn +2 more
2015Journal of Immunotherapy for Cancer2 citations Open access
Semantic Scholar
The mutation of DBC2 in breast cancer patients from the Han ethnic group in Eastern China.
Guoping Fu, Haixin Wang, Hongmei Wu, Mei Wang
2014Hematology/Oncology and Stem Cell Therapy2 citations Open access
Semantic Scholar
Mouse primary T cell phosphotyrosine proteomics enabled by BOOST
Yu-Chua Xien, K. Callahan, Alijah A Griffith, T. Hildebrandt +4 more
2022bioRxiv1 citations Open access
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CARD19, a Novel Negative Regulator of B-Cell Tolerance
Yongwei Zheng, Mei Yu, Yu-Hong Chen, L. Xue +6 more
2021Blood1 citations Open access
Semantic Scholar
Kras Is Critical for CD8 T Cell Antiviral Function
Yu-Hong Chen, Yongwei Zheng, Xiaona You, G. Xin +8 more
20151 citations
Semantic Scholar
Targeting pathogenic alloantibody generation using a chimeric HPA-1a-containing fc fusion protein: A novel treatment for fetal and neonatal alloimmune thrombocytopenia (FNAIT)
Hui-Ying Zhi, Cathy Paddock, Guoping Fu, Jie-Qing Zhu +3 more
2025Blood0 citations
Semantic Scholar
HIT antibodies activate platelets by interacting with a negatively charged epitope on human PF4
Guoping Fu, Daniel Villalobos, De-Min Wang, R. Wen
2025Blood0 citations
Semantic Scholar
Gab3 Plays an Essential Role in CD8 + T-Cell Expansion through Regulating IL-2-Mediated Activation of PI3K/AKT/mTOR and Erk/FoxO Pathways
Guoping Fu, Yongwei Zheng, Gang Xin, Zhengqi Wang +4 more
2023Blood0 citations
Semantic Scholar
CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia
Huiying Zhi, Guoping Fu, R. Wen, De-Min Wang +2 more
2022Blood0 citations Open access
Semantic Scholar
Kras Is Critical for B Cell Lymphopoiesis
Yongwei Zheng, Yu-Hong Chen, Xiaona You, Mei Yu +7 more
20150 citations Open access
Semantic Scholar
AICD, activation-induced cell death; DAG, diacylglycerol; DP, double- positive; IP 3 ,
Guoping Fu, Yu-Hong Chen, Mei Yu, Andrew Podd +10 more
20100 citations
Semantic Scholar
Research advances of EpCAM gene and tumor
Guoping Fu
20090 citations
Semantic Scholar
Phosphorylation of Bcl10 Negatively Regulates T-Cell Receptor-Mediated NF- (cid:2) B Activation (cid:1)
H. Zeng, Lie Di, Guoping Fu, Yu-Hong Chen +4 more
20070 citations
Semantic Scholar

Yongwei Zheng

×12

Wen Zhu×11

James Schuman×5

Lie Di×5

Yinghong He×4

W. Cui×4

D. Newman×4

H. Zeng×4