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W. Casey · SciRah

Researcher profile · Semantic Scholar

W. Casey

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W. Casey — researcher profile on SciRah

h-index: 34
Works: 112
Citations: 3,895

Most-cited papers

Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model.
P. Browne, R. Judson, W. Casey, N. Kleinstreuer +1 more
2015Environmental Science and Technology268 citations
Semantic Scholar
A framework for establishing scientific confidence in new approach methodologies
A. J. van der Zalm, J. Barroso, P. Browne, W. Casey +6 more
2022Archives of Toxicology207 citations Open access
Semantic Scholar
An evaluation framework for new approach methodologies (NAMs) for human health safety assessment.
Stanley T. Parish, M. Aschner, W. Casey, M. Corvaro +9 more
2020Regulatory toxicology and pharmacology : RTP195 citations Open access
Semantic Scholar
Development and Validation of a Computational Model for Androgen Receptor Activity
N. Kleinstreuer, P. Ceger, Eric D. Watt, Matt T. Martin +10 more
2016Chemical Research in Toxicology195 citations Open access
Semantic Scholar
The US Federal Tox21 Program: A Strategic and Operational Plan for Continued Leadership
Russell S. Thomas, R. Paules, A. Simeonov, S. Fitzpatrick +3 more
2018ALTEX194 citations Open access
Semantic Scholar
Non-Animal Methods to Predict Skin Sensitization (II): an assessment of defined approaches
N. Kleinstreuer, S. Hoffmann, N. Alépée, D. Allen +17 more
2018Critical Reviews in Toxicology191 citations Open access
Semantic Scholar
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway
Ruili Huang, S. Sakamuru, Matt T. Martin, David M. Reif +18 more
2014Scientific Reports158 citations Open access
Semantic Scholar
Open-source QSAR models for pKa prediction using multiple machine learning approaches
K. Mansouri, Neal F. Cariello, A. Korotcov, Valery Tkachenko +6 more
2019Journal of Cheminformatics146 citations Open access
Semantic Scholar
In Silico Prediction of Physicochemical Properties of Environmental Chemicals Using Molecular Fingerprints and Machine Learning
Q. Zang, K. Mansouri, A. Williams, R. Judson +3 more
2017Journal of Chemical Information and Modeling146 citations Open access
Semantic Scholar
A Curated Database of Rodent Uterotrophic Bioactivity
N. Kleinstreuer, P. Ceger, D. Allen, J. Strickland +3 more
2015Environmental Health Perspectives117 citations Open access
Semantic Scholar
Application of Adverse Outcome Pathways to U.S. EPA’s Endocrine Disruptor Screening Program
P. Browne, P. Noyes, W. Casey, D. Dix
2017Environmental Health Perspectives104 citations Open access
Semantic Scholar
Integrated Decision Strategies for Skin Sensitization Hazard
J. Strickland, Q. Zang, N. Kleinstreuer, M. Paris +7 more
2016Journal of Applied Toxicology95 citations Open access
Semantic Scholar
Status of Acute Systemic Toxicity Testing Requirements and Data Uses by U.S. Regulatory Agencies
J. Strickland, A. Clippinger, Jeffrey Brown, D. Allen +11 more
2018Regulatory toxicology and pharmacology : RTP90 citations Open access
Semantic Scholar
CATMoS: Collaborative Acute Toxicity Modeling Suite
K. Mansouri, A. Karmaus, Jeremy M. Fitzpatrick, G. Patlewicz +98 more
2021Environmental Health Perspectives88 citations Open access
Semantic Scholar
Advancing Toxicology Research Using In Vivo High Throughput Toxicology with Small Fish Models
Antonio Planchart, C. Mattingly, D. Allen, P. Ceger +14 more
2016ALTEX87 citations Open access
Semantic Scholar
Pathway-Based Predictive Approaches for Non-Animal Assessment of Acute Inhalation Hazard Determination
A. Clippinger, D. Allen, H. Behrsing, K. BéruBé +31 more
2018Toxicology in Vitro85 citations Open access
Semantic Scholar
High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions
Caitlin Lynch, S. Sakamuru, Masato Ooka, Ruili Huang +11 more
2023Annual Review of Pharmacology and Toxicology66 citations Open access
Semantic Scholar
Alternative Approaches for Identifying Acute Systemic Toxicity: Moving from Research to Regulatory Testing
J. Hamm, Kristie Sullivan, A. Clippinger, J. Strickland +20 more
2017Toxicology in Vitro65 citations Open access
Semantic Scholar
Multivariate Models for Prediction of Human Skin Sensitization Hazard
J. Strickland, Q. Zang, M. Paris, D. M. Lehmann +6 more
2016Journal of Applied Toxicology64 citations Open access
Semantic Scholar
An Integrated Chemical Environment with tools for chemical safety testing
S. Bell, J. Abedini, P. Ceger, X. Chang +13 more
2020Toxicology in Vitro61 citations Open access
Semantic Scholar
Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods
S. Casati, K. Aschberger, J. Barroso, W. Casey +12 more
2017Archives of Toxicology61 citations Open access
Semantic Scholar
Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies
A. Karmaus, K. Mansouri, Kimberly To, B. Blake +6 more
2022Toxicological Sciences60 citations Open access
Semantic Scholar
Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials
A. Clippinger, A. Ahluwalia, D. Allen, J. Bonner +13 more
2016Archives of Toxicology56 citations Open access
Semantic Scholar
Adverse Outcome Pathways: From Research to Regulation Scientific Workshop Report
N. Kleinstreuer, Kristie Sullivan, D. Allen, Stephen W. Edwards +7 more
2016Regulatory toxicology and pharmacology : RTP55 citations Open access
Semantic Scholar
Prediction of skin sensitization potency using machine learning approaches
Q. Zang, M. Paris, D. M. Lehmann, S. Bell +6 more
2017Journal of Applied Toxicology53 citations Open access
Semantic Scholar
Application of new approach methodologies: ICE tools to support chemical evaluations
J. Abedini, Bethany Cook, S. Bell, X. Chang +12 more
202148 citations Open access
Semantic Scholar
Validation of Alternative In Vitro Methods to Animal Testing: Concepts, Challenges, Processes and Tools.
C. Griesinger, B. Desprez, S. Coecke, W. Casey +1 more
2016Advances in Experimental Medicine and Biology48 citations
Semantic Scholar
An Integrated Chemical Environment to Support 21st-Century Toxicology
S. Bell, Jason R. Phillips, Alexander Sedykh, Arpit Tandon +8 more
2017Environmental Health Perspectives46 citations Open access
Semantic Scholar
Assessing chemical carcinogenicity: hazard identification, classification, and risk assessment. Insight from a Toxicology Forum state-of-the-science workshop
S. Felter, Virunya S Bhat, P. Botham, D. Bussard +6 more
2021Critical Reviews in Toxicology40 citations Open access
Semantic Scholar
Rethinking chronic toxicity and carcinogenicity assessment for agrochemicals project (ReCAAP): A reporting framework to support a weight of evidence safety assessment without long-term rodent bioassays.
G. Hilton, C. Adcock, G. Akerman, J. Baldassari +17 more
2022Regulatory toxicology and pharmacology : RTP39 citations Open access
Semantic Scholar
Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals
W. Casey, X. Chang, D. Allen, P. Ceger +7 more
2018Environmental Health Perspectives35 citations Open access
Semantic Scholar
Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation.
H. Prior, P. Baldrick, S. Beken, H. Booler +36 more
2020Regulatory toxicology and pharmacology : RTP34 citations Open access
Semantic Scholar
Reflections on the progress towards non-animal methods for acute toxicity testing of chemicals.
H. Prior, W. Casey, I. Kimber, M. Whelan +1 more
2019Regulatory toxicology and pharmacology : RTP34 citations Open access
Semantic Scholar
Identifying Environmental Chemicals as Agonists of the Androgen Receptor by Using a Quantitative High-throughput Screening Platform
Caitlin Lynch, S. Sakamuru, Ruili Huang, D. Stavreva +9 more
2017Toxicology33 citations Open access
Semantic Scholar
Recommendations toward a human pathway-based approach to disease research.
L. Marshall, C. Austin, W. Casey, S. Fitzpatrick +1 more
2018Drug Discovery Today29 citations Open access
Semantic Scholar
Development of a curated Hershberger database.
P. Browne, N. Kleinstreuer, P. Ceger, C. Deisenroth +5 more
2018Reproductive Toxicology29 citations Open access
Semantic Scholar
Lessons learned, challenges, and opportunities: the U.S. Endocrine Disruptor Screening Program.
D. Juberg, S. Borghoff, R. Becker, W. Casey +22 more
2014ALTEX29 citations Open access
Semantic Scholar
A new path forward: the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and National Toxicology Program's Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM).
W. Casey, A. Jacobs, E. Maull, J. Matheson +2 more
2015Journal of the American Association for Laboratory Animal Science28 citations
Semantic Scholar
International Regulatory Uses of Acute Systemic Toxicity Data and Integration of New Approach Methodologies
J. Strickland, Esther M. Haugabrooks, D. Allen, L. Balottin +12 more
2023Critical Reviews in Toxicology27 citations Open access
Semantic Scholar
United States regulatory requirements for skin and eye irritation testing
N. Choksi, J. Truax, Adrienne Layton, J. Matheson +11 more
2018Cutaneous and Ocular Toxicology25 citations Open access
Semantic Scholar
Application of Reverse Dosimetry to Compare In Vitro and In Vivo Estrogen Receptor Activity
X. Chang, N. Kleinstreuer, P. Ceger, Jui-Hua Hsieh +2 more
201525 citations
Semantic Scholar
Open source software implementation of an integrated testing strategy for skin sensitization potency based on a Bayesian network.
Jason R. Pirone, Marjolein V. Smith, N. Kleinstreuer, T. Burns +6 more
2014ALTEX21 citations Open access
Semantic Scholar
International Harmonization and Cooperation in the Validation of Alternative Methods.
J. Barroso, Ilkyu Ahn, C. Caldeira, P. Carmichael +24 more
2016Advances in Experimental Medicine and Biology20 citations
Semantic Scholar
A robotic MCF-7:WS8 cell proliferation assay to detect agonist and antagonist estrogenic activity.
Chun Z. Yang, W. Casey, M. Stoner, G. Kollessery +2 more
2014Toxicological Sciences20 citations Open access
Semantic Scholar
Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite
K. Mansouri, A. Karmaus, Jeremy M. Fitzpatrick, G. Patlewicz +98 more
2021Environmental Health Perspectives16 citations Open access
Semantic Scholar
A global initiative to refine acute inhalation studies through the use of 'evident toxicity' as an endpoint: Towards adoption of the fixed concentration procedure.
F. Sewell, I. Ragan, T. Marczylo, Brian P. Anderson +17 more
2015Regulatory toxicology and pharmacology : RTP16 citations Open access
Semantic Scholar
In vitro to in vivo extrapolation for high throughput prioritization and decision making
S. Bell, Xiaoqing Chang, J. Wambaugh, D. Allen +20 more
2017Toxicology in Vitro15 citations Open access
Semantic Scholar
Systems Biology for Organotypic Cell Cultures
S. Grego, E. Dougherty, Francis J. Alexander, S. Auerbach +18 more
2016ALTEX15 citations Open access
Semantic Scholar
Report on the international workshop on alternatives to the murine histamine sensitization test (HIST) for acellular pertussis vaccines: state of the science and the path forward.
R. Isbrucker, J. Arciniega, R. Mcfarland, J. Chapsal +14 more
2014Biologicals (Print)14 citations
Semantic Scholar
Advances in the Development and Validation of Test Methods in the United States
W. Casey
2016Toxicological Research13 citations Open access
Semantic Scholar

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N. Kleinstreuer×26
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J. Strickland×14
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P. Ceger×8
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A. Lowit — researcher profile on SciRah

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A. Clippinger×6

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A. Clippinger — researcher profile on SciRah

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N. Choksi — researcher profile on SciRah