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G. Patlewicz · SciRah

Researcher profile · Semantic Scholar

G. Patlewicz

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G. Patlewicz — researcher profile on SciRah

h-index: 56
Works: 212
Citations: 13K

Most-cited papers

A New OECD Definition for Per- and Polyfluoroalkyl Substances.
Zhan-Yun Wang, A. Buser, I. Cousins, Silvia Demattio +8 more
2021Environmental Science and Technology489 citations
Semantic Scholar
The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency.
R. Thomas, T. Bahadori, Timothy J. Buckley, J. Cowden +38 more
2019Toxicological Sciences322 citations Open access
Semantic Scholar
GRADE Guidelines 30: the GRADE approach to assessing the certainty of modeled evidence—An overview in the context of health decision-making
J. Brożek, Carlos Canelo-Aybar, E. Akl, J. Bowen +40 more
2020Journal of Clinical Epidemiology282 citations Open access
Semantic Scholar
In silico toxicology protocols
G. Myatt, Ernst Ahlberg, Y. Akahori, D. Allen +80 more
2018Regulatory toxicology and pharmacology : RTP195 citations Open access
Semantic Scholar
Bioactivity Profiling of Per- and Polyfluoroalkyl Substances (PFAS) Identifies Potential Toxicity Pathways Related to Molecular Structure.
K. Houck, G. Patlewicz, A. Richard, A. Williams +6 more
2021Toxicology115 citations Open access
Semantic Scholar
A Chemical Category-Based Prioritization Approach for Selecting 75 Per- and Polyfluoroalkyl Substances (PFAS) for Tiered Toxicity and Toxicokinetic Testing
G. Patlewicz, A. Richard, A. Williams, C. Grulke +8 more
2019Environmental Health Perspectives90 citations Open access
Semantic Scholar
Internationalization of Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology
C. Rovida, T. Barton-Maclaren, E. Benfenati, F. Caloni +27 more
2020ALTEX89 citations Open access
Semantic Scholar
CATMoS: Collaborative Acute Toxicity Modeling Suite
K. Mansouri, A. Karmaus, Jeremy M. Fitzpatrick, G. Patlewicz +98 more
2021Environmental Health Perspectives88 citations Open access
Semantic Scholar
Pathway-Based Predictive Approaches for Non-Animal Assessment of Acute Inhalation Hazard Determination
A. Clippinger, D. Allen, H. Behrsing, K. BéruBé +31 more
2018Toxicology in Vitro85 citations Open access
Semantic Scholar
Predictive Models for Acute Oral Systemic Toxicity: A Workshop to Bridge the Gap from Research to Regulation
N. Kleinstreuer, A. Karmaus, K. Mansouri, D. Allen +2 more
2018Computational Toxicology77 citations Open access
Semantic Scholar
Assembly and Curation of Lists of Per- and Polyfluoroalkyl Substances (PFAS) to Support Environmental Science Research
A. Williams, Linda G. T. Gaines, C. Grulke, Charles N. Lowe +6 more
2022Frontiers in Environmental Science69 citations Open access
Semantic Scholar
Generalized Read-Across (GenRA): A workflow implemented into the EPA CompTox Chemicals Dashboard.
G. Helman, Imran Shah, Antony Williams, J. Edwards +2 more
2019ALTEX63 citations Open access
Semantic Scholar
Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies
A. Karmaus, K. Mansouri, Kimberly To, B. Blake +6 more
2022Toxicological Sciences60 citations Open access
Semantic Scholar
Navigating through the minefield of read-across frameworks: A commentary perspective
G. Patlewicz, M. Cronin, G. Helman, J. Lambert +2 more
201858 citations Open access
Semantic Scholar
Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) In Vitro Toxicity Testing for Developmental Neurotoxicity.
K. Carstens, Theresa F Freudenrich, Kathleen A. Wallace, Seline Choo +9 more
2023Chemical Research in Toxicology55 citations Open access
Semantic Scholar
Systematic Evidence Map for Over One Hundred and Fifty Per- and Polyfluoroalkyl Substances (PFAS)
L. Carlson, M. Angrish, A. Shirke, E. Radke +23 more
2022Environmental Health Perspectives53 citations Open access
Semantic Scholar
NAM-supported read-across: From case studies to regulatory guidance in safety assessment.
C. Rovida, S. Escher, M. Herzler, S. H. Bennekou +10 more
2021ALTEX48 citations Open access
Semantic Scholar
Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a Risk-Based Prioritization Approach for thousands of chemicals.
G. Patlewicz, J. Wambaugh, S. Felter, T. Simon +1 more
2018Computational Toxicology40 citations Open access
Semantic Scholar
Non‐animal assessment of skin sensitization hazard: Is an integrated testing strategy needed, and if so what should be integrated?
D. Roberts, G. Patlewicz
2018Journal of Applied Toxicology39 citations Open access
Semantic Scholar
Evaluation of Existing QSAR Models and Structural Alerts and Development of New Ensemble Models for Genotoxicity Using a Newly Compiled Experimental Dataset.
Prachi Pradeep, R. Judson, D. DeMarini, N. Keshava +7 more
2021Computational Toxicology37 citations Open access
Semantic Scholar
Using Chemical Structure Information to Develop Predictive Models for In Vitro Toxicokinetic Parameters to Inform High-throughput Risk-assessment.
Prachi Pradeep, G. Patlewicz, Robert G. Pearce, J. Wambaugh +2 more
2020Computational Toxicology35 citations Open access
Semantic Scholar
Exploring Current Read-across Applications and Needs Among Selected U.S. Federal Agencies
G. Patlewicz, L. Lizarraga, D. Rua, D. Allen +14 more
2019Regulatory toxicology and pharmacology : RTP35 citations Open access
Semantic Scholar
Towards systematic read-across using Generalised Read-Across (GenRA).
G. Patlewicz, Imran Shah
2022Computational Toxicology33 citations Open access
Semantic Scholar
Advancing the science of a read-across framework for evaluation of data-poor chemicals incorporating systematic and new approach methods.
L. Lizarraga, G. Suter, J. Lambert, G. Patlewicz +3 more
2022Regulatory toxicology and pharmacology : RTP31 citations
Semantic Scholar
Predicting estrogen receptor activation by a group of substituted phenols: An integrated approach to testing and assessment case study.
Francina Webster, M. Gagne, G. Patlewicz, Prachi Pradeep +3 more
2019Regulatory toxicology and pharmacology : RTP28 citations Open access
Semantic Scholar
A New CSRML Structure-Based Fingerprint Method for Profiling and Categorizing Per- and Polyfluoroalkyl Substances (PFAS)
A. Richard, Ryan R. Lougee, M. Adams, Hannah Hidle +6 more
2023Chemical Research in Toxicology27 citations Open access
Semantic Scholar
Towards reproducible structure-based chemical categories for PFAS to inform and evaluate toxicity and toxicokinetic testing.
G. Patlewicz, A. Richard, A. Williams, R. Judson +1 more
2022Computational Toxicology26 citations Open access
Semantic Scholar
Implementing In Vitro Bioactivity Data to Modernize Priority Setting of Chemical Inventories
Marc A. Beal, M. Gagne, S. Kulkarni, G. Patlewicz +2 more
2021ALTEX26 citations Open access
Semantic Scholar
Comparing the performance and coverage of selected in silico (liver) metabolism tools relative to reported studies in the literature to inform analogue selection in read-across: A case study.
M. Boyce, Brian Meyer, C. Grulke, L. Lizarraga +1 more
2021Computational Toxicology26 citations Open access
Semantic Scholar
Identification of novel activators of the metal responsive transcription factor (MTF-1) using a gene expression biomarker in a microarray compendium.
Abigail C. Jackson, Jie Liu, Beena Vallanat, Carlton P. Jones +3 more
2020Metallomics25 citations Open access
Semantic Scholar
Extending the Generalised Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance.
G. Helman, Imran Shah, G. Patlewicz
2018Computational Toxicology24 citations Open access
Semantic Scholar
Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study.
Tia Tate, J. Wambaugh, G. Patlewicz, Imran Shah
2021Computational Toxicology23 citations Open access
Semantic Scholar
Evaluating potential refinements to existing Threshold of Toxicological Concern (TTC) values for environmentally-relevant compounds.
M. Nelms, Prachi Pradeep, G. Patlewicz
2019Regulatory toxicology and pharmacology : RTP23 citations Open access
Semantic Scholar
Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods
C. Zwickl, Jessica C. Graham, R. Jolly, A. Bassan +39 more
2022Computational Toxicology21 citations Open access
Semantic Scholar
Evaluation of 147 Perfluoroalkyl Substances for Immunotoxic and Other (Patho)physiological Activities through Phenotypic Screening of Human Primary Cells
K. Houck, K. P. Friedman, M. Feshuk, G. Patlewicz +6 more
2022ALTEX19 citations Open access
Semantic Scholar
A scheme to evaluate structural alerts to predict toxicity – Assessing confidence by characterising uncertainties
M. Cronin, F. Bauer, Mark Bonnell, Bruno Campos +9 more
2022Regulatory toxicology and pharmacology : RTP19 citations Open access
Semantic Scholar
Transitioning the Generalised Read-Across approach (GenRA) to quantitative predictions: A case study using acute oral toxicity data.
G. Helman, Imran Shah, G. Patlewicz
2019Computational Toxicology19 citations Open access
Semantic Scholar
Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis
M. Boyce, K. Favela, J. Bonzo, Alex Chao +10 more
2023Frontiers in Toxicology18 citations Open access
Semantic Scholar
Derivation of New Threshold of Toxicological Concern Values for Exposure via Inhalation for Environmentally-Relevant Chemicals
M. Nelms, G. Patlewicz
2020Frontiers in Toxicology18 citations Open access
Semantic Scholar
An evaluation of the performance of selected (Q)SARs/expert systems for predicting acute oral toxicity
M. Nelms, A. Karmaus, G. Patlewicz
2020Computational Toxicology18 citations Open access
Semantic Scholar
Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities.
Imran Shah, J. Bundy, Bryant A. Chambers, L. Everett +5 more
2022Chemical Research in Toxicology16 citations Open access
Semantic Scholar
Erratum: CATMoS: Collaborative Acute Toxicity Modeling Suite
K. Mansouri, A. Karmaus, Jeremy M. Fitzpatrick, G. Patlewicz +98 more
2021Environmental Health Perspectives16 citations Open access
Semantic Scholar
“In Litero” Screening: Retrospective Evaluation of Clinical Evidence to Establish a Reference List of Human Chemical Respiratory Sensitizers
Jessica Ponder, R. Rajagopal, M. Singal, Nancy C. Baker +4 more
2022Frontiers in Toxicology15 citations Open access
Semantic Scholar
Generalized Read-Across prediction using genra-py
Imran Shah, Tia Tate, G. Patlewicz
2021Bioinform.15 citations Open access
Semantic Scholar
Integrating data gap filling techniques: A case study predicting TEFs for neurotoxicity TEQs to facilitate the hazard assessment of polychlorinated biphenyls
Prachi Pradeep, L. Carlson, R. Judson, G. Lehmann +1 more
2019Regulatory toxicology and pharmacology : RTP15 citations Open access
Semantic Scholar
A Mechanistic Framework for Integrating Chemical Structure and High-Throughput Screening Results to Improve Toxicity Predictions.
M. Nelms, C. Mellor, S. Enoch, R. Judson +5 more
2018Computational Toxicology15 citations Open access
Semantic Scholar
Quantitative prediction of repeat dose toxicity values using GenRA.
G. Helman, G. Patlewicz, Imran Shah
2019Regulatory toxicology and pharmacology : RTP14 citations Open access
Semantic Scholar
A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS)
R. Judson, Doris Smith, Michael J. Devito, J. Wambaugh +11 more
2024Toxics13 citations Open access
Semantic Scholar
Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research
K. Roell, Lauren E Koval, Rebecca R. Boyles, G. Patlewicz +7 more
2022Frontiers in Toxicology12 citations Open access
Semantic Scholar
Identification of Branched and Linear Forms of PFOA and Potential Precursors: A User-Friendly SMILES Structure-based Approach
A. Richard, Hannah Hidle, G. Patlewicz, A. Williams
2022Frontiers in Environmental Science12 citations Open access
Semantic Scholar

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