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Geou-Yarh Liou · SciRah

Researcher profile · Semantic Scholar

Geou-Yarh Liou

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Geou-Yarh Liou — researcher profile on SciRah

h-index: 21
Works: 53
Citations: 5,651

Most-cited papers

Reactive oxygen species in cancer
Geou-Yarh Liou, P. Storz
2010Free radical research3,114 citations Open access
Semantic Scholar
EGF Receptor is Required for KRAS-induced Pancreatic Tumorigenesis
Christine M. Ardito, B. Grüner, Kenneth K. Takeuchi, Clara Lubeseder-Martellato +22 more
2012Cancer Cell521 citations Open access
Semantic Scholar
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
Geou-Yarh Liou, Heike R. Döppler, B. Necela, Murli Krishna +3 more
2013Journal of Cell Biology287 citations Open access
Semantic Scholar
Mutant Kras-induced mitochondrial oxidative stress in acinar cells upregulates EGFR signaling to drive formation of pancreatic precancerous lesions
Geou-Yarh Liou, Heike R. Döppler, Kathleen E. DelGiorno, Lizhi Zhang +4 more
2016Cell Reports232 citations Open access
Semantic Scholar
Transcription Repressor Slug Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
J. Shih, Meng-Feng Tsai, Tzu-Hua Chang, Yih-Leong Chang +11 more
2005Clinical Cancer Research222 citations
Semantic Scholar
Mutant Kras-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions
Geou-Yarh Liou, Heike R. Döppler, B. Necela, B. Edenfield +3 more
2014Cancer Discovery187 citations Open access
Semantic Scholar
CD133 as a Regulator of Cancer Metastasis through the Cancer Stem Cells
Geou-Yarh Liou
2018International Journal of Biochemistry and Cell Biology122 citations Open access
Semantic Scholar
Presence of Interleukin-13 at pancreatic ADM/PanIN lesions alters macrophage populations and mediates pancreatic tumorigenesis
Geou-Yarh Liou, Ligia I. Bastea, Alicia K Fleming, Heike R. Döppler +5 more
2017Cell Reports111 citations Open access
Semantic Scholar
Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia
Geou-Yarh Liou, Heike R. Döppler, U. Braun, Richard Panayiotou +8 more
2015Nature Communications99 citations Open access
Semantic Scholar
NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar–Ductal Transdifferentiation in the Pancreas
N. Chen, Garima Singh, A. Koenig, Geou-Yarh Liou +11 more
2015Gastroenterology93 citations Open access
Semantic Scholar
Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity.
Show-Mei Chuang, Geou-Yarh Liou, Jia-Ling Yang
2000Carcinogenesis91 citations Open access
Semantic Scholar
Macrophage Cytokines Enhance Cell Proliferation of Normal Prostate Epithelial Cells through Activation of ERK and Akt
T. Dang, Geou-Yarh Liou
2018Scientific Reports62 citations Open access
Semantic Scholar
Detecting Reactive Oxygen Species by Immunohistochemistry
Geou-Yarh Liou, P. Storz
2015Methods in molecular biology51 citations Open access
Semantic Scholar
Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity
Heike R. Döppler, Geou-Yarh Liou, P. Storz
2013PLoS ONE43 citations Open access
Semantic Scholar
NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation
E. Hessmann, Jin-San Zhang, N. Chen, Marie C. Hasselluhn +5 more
2015Stem Cells International42 citations Open access
Semantic Scholar
Glycogen synthase kinase-3β ablation limits pancreatitis induced acinar-to-ductal metaplasia.
L. Ding, Geou-Yarh Liou, D. Schmitt, P. Storz +2 more
2017Journal of Pathology33 citations Open access
Semantic Scholar
Impact of Immune Cells in the Tumor Microenvironment of Prostate Cancer Metastasis
Justin K. Messex, Geou-Yarh Liou
2023Life32 citations Open access
Semantic Scholar
Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer
Geou-Yarh Liou, P. Storz
2015Oncoscience31 citations Open access
Semantic Scholar
Macrophages Cytokine Spp1 Increases Growth of Prostate Intraepithelial Neoplasia to Promote Prostate Tumor Progression
Justin K. Messex, Crystal J. Byrd, Mikalah U. Thomas, Geou-Yarh Liou
2022International Journal of Molecular Sciences30 citations Open access
Semantic Scholar
Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions
Ligia I. Bastea, Geou-Yarh Liou, Veethika Pandey, Alicia K Fleming +8 more
2019Cancer Research29 citations Open access
Semantic Scholar
Diagnostic Bioliquid Markers for Pancreatic Cancer: What We Have vs. What We Need
Geou-Yarh Liou, Crystal J. Byrd
2023Cancers24 citations Open access
Semantic Scholar
Targeting BTK Signaling in the Microenvironment of Solid Tumors as a Feasible Cancer Therapy Option
Justin K. Messex, Geou-Yarh Liou
2021Cancers21 citations Open access
Semantic Scholar
Ym1+ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, B. Edenfield +2 more
2022iScience20 citations Open access
Semantic Scholar
Inflammatory Cytokine Signaling during Development of Pancreatic and Prostate Cancers
Geou-Yarh Liou
2017Journal of Immunological Research18 citations Open access
Semantic Scholar
Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, B. Edenfield +4 more
2021iScience16 citations Open access
Semantic Scholar
Generation of Hydrogen Peroxide and Downstream Protein Kinase D1 Signaling Is a Common Feature of Inducers of Pancreatic Acinar-to-Ductal Metaplasia
Heike R. Döppler, Geou-Yarh Liou, P. Storz
2022Antioxidants15 citations Open access
Semantic Scholar
Macrophages Expedite Cell Proliferation of Prostate Intraepithelial Neoplasia through Their Downstream Target ERK
Mikalah U. Thomas, Justin K. Messex, T. Dang, S. Abdulkadir +2 more
2020The FEBS Journal15 citations Open access
Semantic Scholar
Signaling of Macrophages that Contours the Tumor Microenvironment for Promoting Cancer Development
Justin K. Messex, Crystal J. Byrd, Geou-Yarh Liou
2020Cells15 citations Open access
Semantic Scholar
Oncogenic Kras-Mediated Cytokine CCL15 Regulates Pancreatic Cancer Cell Migration and Invasion through ROS
Justin K. Messex, Kiyah L A Adams, W. Hawkins, D. DeNardo +3 more
2022Cancers14 citations Open access
Semantic Scholar
Paracrine Secretion of TGF-β by Ductal Cells Promotes Acinar-to-Ductal Metaplasia in Cultured Human Exocrine Pancreas Tissues
Naoki Akanuma, Jun Liu, Geou-Yarh Liou, Xue Yin +5 more
2017Pancreas13 citations Open access
Semantic Scholar
Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
Geou-Yarh Liou, Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea +1 more
2023iScience10 citations Open access
Semantic Scholar
Involvement of Reactive Oxygen Species in Prostate Cancer and Its Disparity in African Descendants
Geou-Yarh Liou, Reauxqkwuanzyiia C’lay-Pettis, Sravankumar Kavuri
2024International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases
Geou-Yarh Liou, Crystal J. Byrd, P. Storz, Justin K. Messex
2024International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
New biochemical approaches towards understanding the Parkinson's disease-associated kinase, LRRK2.
Geou-Yarh Liou, K. Gallo
2009Biochemical Journal9 citations
Semantic Scholar
Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.
Geou-Yarh Liou, Hua Zhang, E. Miller, S. Seibold +2 more
2010Biochemical Journal8 citations
Semantic Scholar
Protein kinase D enzymes – novel kinase targets in pancreatic cancer
Geou-Yarh Liou, P. Storz
2015Expert Review of Gastroenterology & Hepatology6 citations Open access
Semantic Scholar
Increased Levels of Oxidative Stress in Human Prostate Intraepithelial Neoplasia and Prostate Cancer: Evidence from 4-Hydroxyneonal Detection and Its Implications
Geou-Yarh Liou, Woojung Kim, T. Hobbs
2025Antioxidants2 citations Open access
Semantic Scholar
A bright future for protein kinase D1 as a drug target to prevent or treat pancreatic cancer
Geou-Yarh Liou, P. Storz, M. Leitges
2016Molecular & Cellular Oncology2 citations Open access
Semantic Scholar
Pancreatic oncogenic signaling cascades converge at Protein Kinase D1
Geou-Yarh Liou, M. Leitges, P. Storz
2015Cell Cycle1 citations Open access
Semantic Scholar
Cytokines IL-6, IL-10, and CCL5 Secreted by Infiltrating B Cells Promote Cell Migration of Human Prostate Cancer Cell Lines
Crystal J. Byrd, M. Evans, Woojung Kim, Quintera Knight +1 more
2026Oncology Research0 citations Open access
Semantic Scholar
Abstract 5325: Cytokine CCL9, new downstream target of oncogene Kras to modulate acinar-to-ductal metaplasia during pancreatic cancer initiation
Geou-Yarh Liou, Justin K. Messex, Crystal J. Byrd
2024Cancer Research0 citations
Semantic Scholar
Abstract 637: Cytokine CCL9 mediates oncogenic Kras-induced pancreatic acinar-to-ductal metaplasia through ROS
Geou-Yarh Liou, Justin K. Messex, Kiyah L A Adams
2023Cancer Research0 citations
Semantic Scholar
Abstract 3631: Infiltrating Bruton’s tyrosine kinase expressed B cells effects on prostate cancer metastasis
Crystal J. Byrd, Geou-Yarh Liou
2023Cancer Research0 citations
Semantic Scholar
Catching pancreatic cancer early: the promise of affordable biomarkers to regularly screen high-risk individuals
Geou-Yarh Liou
2023Translational Gastroenterology and Hepatology0 citations Open access
Semantic Scholar
Abstract A59: Crosstalk of different macrophage populations with pancreatic acinar or PanIN cells and contribution to development of pancreatic cancer
Geou-Yarh Liou, Heike R Doeppler, Ligia I. Bastea, P. Storz
20160 citations
Semantic Scholar
Strategies to Target Pancreatic Cancer
Geou-Yarh Liou, P. Storz
20160 citations
Semantic Scholar
Abstract PR01: Oncogenic Kras-induced mitochondrial oxidative stress in pancreatic acini modulates the formation of precancerous lesions through autocrine EGFR signaling
Geou-Yarh Liou, Heike R Doeppler, Kathleen E. DelGirono, H. Crawford +2 more
20160 citations
Semantic Scholar
Abstract LB-342: Macrophage-secreted cytokines drive acinar-to-ductal metaplasia of the pancreas.
Geou-Yarh Liou, Heike R Doeppler, P. Storz
20130 citations
Semantic Scholar
Elevated expression of EGFL7 in pancreatitis induces acinar-to-ductal metaplasia of the pancreas
Geou-Yarh Liou, P. Storz
20130 citations
Semantic Scholar
Abstract 1123: Transforming growth factor α signaling in pancreatic acinar-to-ductal metaplasia
Geou-Yarh Liou, P. Storz
20110 citations
Semantic Scholar

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