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K. Gallo · SciRah

Researcher profile · Semantic Scholar

K. Gallo

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K. Gallo — researcher profile on SciRah

h-index: 24
Works: 62
Citations: 2,810

Most-cited papers

LRRK2 in Parkinson's disease: protein domains and functional insights.
I. Mata, W. Wedemeyer, M. Farrer, Julie P. Taylor +1 more
2006Trends in Neurosciences513 citations
Semantic Scholar
Signalling: Mixed-lineage kinase control of JNK and p38 MAPK pathways
K. Gallo, G. Johnson
2002Nature reviews. Molecular cell biology402 citations
Semantic Scholar
RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP.
G. Gaudino, A. Follenzi, L. Naldini, Chiara Collesi +4 more
1994EMBO Journal320 citations Open access
Semantic Scholar
The Mixed Lineage Kinase SPRK Phosphorylates and Activates the Stress-activated Protein Kinase Activator, SEK-1*
A. Rana, K. Gallo, P. Godowski, Shu-ichi Hirai +4 more
1996Journal of Biological Chemistry226 citations Open access
Semantic Scholar
Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.
K. Gallo, M. Mark, David T. Scadden, Zhengyu Wang +2 more
1994Journal of Biological Chemistry126 citations Open access
Semantic Scholar
MLK3 regulates paxillin phosphorylation in chemokine-mediated breast cancer cell migration and invasion to drive metastasis.
Jian Chen, K. Gallo
2012Cancer Research87 citations Open access
Semantic Scholar
Autoinhibition of Mixed Lineage Kinase 3 through Its Src Homology 3 Domain*
Hua Zhang, K. Gallo
2001Journal of Biological Chemistry83 citations Open access
Semantic Scholar
Cdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylation.
B. Böck, Panayiotis O. Vacratsis, Erion Qamirani, K. Gallo
2000Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Cdc42 Induces Activation Loop Phosphorylation and Membrane Targeting of Mixed Lineage Kinase 3*
Yan Du, B. Böck, Karen A. Schachter, Mary Chao +1 more
2005Journal of Biological Chemistry79 citations Open access
Semantic Scholar
E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration
D. Hollern, Matthew R. Swiatnicki, J. Rennhack, Sean A. Misek +5 more
2019Scientific Reports78 citations Open access
Semantic Scholar
MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells
Jian Chen, E. Miller, K. Gallo
2010Oncogene78 citations
Semantic Scholar
Hsp90/p50cdc37 Is Required for Mixed-lineage Kinase (MLK) 3 Signaling*
Hua Zhang, Wei Wu, Yan Du, S. J. Santos +4 more
2004Journal of Biological Chemistry66 citations Open access
Semantic Scholar
MLK3 regulates FRA-1 and MMPs to drive invasion and transendothelial migration in triple-negative breast cancer cells
Chotirat Rattanasinchai, B. Llewellyn, S. Conrad, K. Gallo
2017Oncogenesis54 citations Open access
Semantic Scholar
Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells
Sean A. Misek, K. Appleton, T. Dexheimer, Erika M. Lisabeth +4 more
2019Oncogene53 citations Open access
Semantic Scholar
Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters
M. Sudhakaran, M. Parra, Hayden Stoub, K. Gallo +1 more
2020Biochemical Pharmacology50 citations Open access
Semantic Scholar
The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis
Christopher J. Occhiuto, J. Moerland, Ana S. Leal, K. Gallo +1 more
2023Molecules and Cells43 citations Open access
Semantic Scholar
MLK3 Signaling in Cancer Invasion
Chotirat Rattanasinchai, K. Gallo
2016Cancers43 citations Open access
Semantic Scholar
The 18-kDa Translocator Protein (TSPO) Disrupts Mammary Epithelial Morphogenesis and Promotes Breast Cancer Cell Migration
Xiaoting Wu, K. Gallo
2013PLoS ONE42 citations Open access
Semantic Scholar
Dynamic Positive Feedback Phosphorylation of Mixed Lineage Kinase 3 by JNK Reversibly Regulates Its Distribution to Triton-soluble Domains*
Karen A. Schachter, Yan Du, A. Lin, K. Gallo
2006Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Identification of in vivo phosphorylation sites of MLK3 by mass spectrometry and phosphopeptide mapping.
Panayiotis O. Vacratsis, B. Phinney, D. Gage, K. Gallo
2002Biochemistry39 citations
Semantic Scholar
Targeting HSP90 to halt neurodegeneration.
K. Gallo
2006Chemistry and Biology32 citations Open access
Semantic Scholar
Solid-phase synthesis, separation, and stereochemical aspects of P-chiral methane- and 4,4'-dimethoxytriphenylmethanephosphonate analogs of oligodeoxyribonucleotides
W. Stec, G. Zon, W. Egan, R. Byrd +2 more
198531 citations
Semantic Scholar
Phosphorylation of golgin-160 by mixed lineage kinase 3
Hyukjin Cha, Barbara L. Smith, K. Gallo, C. Machamer +1 more
2004Journal of Cell Science29 citations Open access
Semantic Scholar
EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion
Sean A. Misek, Jian Chen, Laura E Schroeder, Chotirat Rattanasinchai +3 more
2017Molecular Cancer Research26 citations
Semantic Scholar
Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation.
K. Gallo, Edmund Ellsworth, Hayden Stoub, S. Conrad
2019Pharmacology and Therapeutics19 citations Open access
Semantic Scholar
Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis
Li-Min Wang, K. Gallo, S. Conrad
2013OncoTarget19 citations Open access
Semantic Scholar
Loss of MLK3 signaling impedes ulcer healing by modulating MAPK signaling in mouse intestinal mucosa.
P. Kovalenko, Lyudmyla Kunovska, Jing Chen, K. Gallo +1 more
2012American Journal of Physiology - Gastrointestinal and Liver Physiology19 citations Open access
Semantic Scholar
Endothelin-1 Enriched Tumor Phenotype Predicts Breast Cancer Recurrence
D. Tamkus, A. Sikorskii, K. Gallo, D. Wiese +5 more
2013ISRN Oncology15 citations Open access
Semantic Scholar
Synthesis and Antitumor Activity of Cyclophosphamide Analogues.
S. M. Ludeman, V. L. Boyd, J. B. Regan, K. Gallo +2 more
198615 citations
Semantic Scholar
Ibrutinib Blocks YAP1 Activation and Reverses BRAF Inhibitor Resistance in Melanoma Cells
Sean A. Misek, Patrick A. Newbury, E. Chekalin, S. Paithankar +4 more
2020Molecular Pharmacology10 citations Open access
Semantic Scholar
Inhibition of the Myocardin-Related Transcription Factor Pathway Increases Efficacy of Trametinib in NRAS-Mutant Melanoma Cell Lines
K. Appleton, C. Palsuledesai, Sean A. Misek, Maja K. Blake +4 more
2019bioRxiv10 citations Open access
Semantic Scholar
Cdc42-induced Activation of the Mixed-Lineage Kinase SPRKin Vivo
B. Böck, Panayiotis O. Vacratsis, Erion Qamirani, K. Gallo
2000Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Exploring structural effects in a new class of NRF2 inhibitors.
Zhilin Hou, Lizbeth Lockwood, Di Zhang, Christopher J. Occhiuto +6 more
2023RSC Medicinal Chemistry9 citations Open access
Semantic Scholar
New biochemical approaches towards understanding the Parkinson's disease-associated kinase, LRRK2.
Geou-Yarh Liou, K. Gallo
2009Biochemical Journal9 citations
Semantic Scholar
Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.
Geou-Yarh Liou, Hua Zhang, E. Miller, S. Seibold +2 more
2010Biochemical Journal8 citations
Semantic Scholar
Inhibition of MLK3 Decreases Proliferation and Increases Antiproliferative Activity of Epidermal Growth Factor Receptor (EGFR) Inhibitor in Pancreatic Cancer Cell Lines
S. Chandana, C. Leece, K. Gallo, B. Madhukar +1 more
20087 citations Open access
Semantic Scholar
Synthesis of reactive metabolite-analogues of cyclophosphamide for comparisons of NMR kinetic parameters and anticancer screening data.
S. M. Ludeman, V. L. Boyd, J. B. Regan, K. Gallo +2 more
1986Drugs under experimental and clinical research7 citations
Semantic Scholar
BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
Sean A. Misek, Bardees M. Foda, T. Dexheimer, M. Akram +4 more
2021bioRxiv6 citations Open access
Semantic Scholar
Inhibition of the Rho/MRTF pathway improves the response of BRAF-resistant melanoma to PD1/PDL1 blockade
Bardees M. Foda, Sean A. Misek, K. Gallo, R. Neubig
2023bioRxiv5 citations Open access
Semantic Scholar
Mixed lineage kinase 3 inhibits phorbol myristoyl acetate-induced DNA synthesis but not osteopontin expression in rat mesangial cells
N. Parameswaran, Carolyn S. Hall, B. Böck, H. Sparks +2 more
2002Molecular and Cellular Biochemistry3 citations
Semantic Scholar
Fast atom bombardment mass spectra ofO-isopropyl oligodeoxyribonucleotide triesters
L. R. Phillips, K. Gallo, G. Zon, W. Stec +1 more
19853 citations
Semantic Scholar
Rho-mediated MRTF and YAP1 activation contributes to BRAF inhibitor resistance in Sox9High/Sox10Low melanoma cells.
Sean A. Misek, K. Appleton, T. Dexheimer, E. Lisabeth +4 more
20182 citations Open access
Semantic Scholar
Mixed Lineage Kinase 3 Inhibits Platelet-Derived Growth Factor-Stimulated DNA Synthesis and Matrix mRNA Expression in Mesangial Cells
N. Parameswaran, Carolyn S. Hall, Barbara Boeck, H. Sparks +2 more
2002Cellular Physiology and Biochemistry2 citations
Semantic Scholar
Fast atom bombardment mass spectra of O‐isopropyl oligodeoxyribonucleotide triesters
L. R. Phillips, K. Gallo, G. Zon, W. Stec +1 more
19852 citations
Semantic Scholar
Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells
Sean A. Misek, K. Appleton, T. Dexheimer, Erika M. Lisabeth +4 more
2018bioRxiv1 citations Open access
Semantic Scholar
Abstract 2374: Mixed-Lineage Kinase 3 signals through the FRA1-MMP1 axis to drive triple-negative breast cancer invasion and transendothelial migration
Chotirat Rattanasinchai, B. Llewellyn, S. Conrad, K. Gallo
20171 citations
Semantic Scholar
P2-03-06: Endothelin-1/Endothelin A Receptor Signalling in Breast Cancer.
D. Tamkus, C. Leece, K. Gallo, B. Madhukar +1 more
20111 citations
Semantic Scholar
Targeting HSP 90 to Halt Neurodegeneration
K. Gallo
20061 citations
Semantic Scholar
Abstract B07: Rho-mediated gene transcription promotes BRAFi resistance in de-differentiated melanoma cells
Sean A. Misek, K. Appleton, T. Dexheimer, E. Lisabeth +4 more
2020Cancer Research0 citations
Semantic Scholar
Abstract 5895: Targeting RhoA-regulated gene transcription in drug-resistant melanoma
Sean A. Misek, K. Gallo, R. Neubig
2017Experimental and Molecular Therapeutics0 citations
Semantic Scholar

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