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Ligia I. Bastea · SciRah

Researcher profile · Semantic Scholar

Ligia I. Bastea

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Ligia I. Bastea — researcher profile on SciRah

h-index: 16
Works: 26
Citations: 1,021

Most-cited papers

Alzheimer’s risk factors age, APOE genotype, and sex drive distinct molecular pathways
Na Zhao, Ying-Xue Ren, Yu Yamazaki, Wen-Hui Qiao +28 more
2020Neuron193 citations Open access
Semantic Scholar
Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function
Chia-Chen Liu, Jing Zhao, Yuan Fu, Yasuteru Inoue +36 more
2022Nature Neuroscience150 citations Open access
Semantic Scholar
Presence of Interleukin-13 at pancreatic ADM/PanIN lesions alters macrophage populations and mediates pancreatic tumorigenesis
Geou-Yarh Liou, Ligia I. Bastea, Alicia K Fleming, Heike R. Döppler +5 more
2017Cell Reports111 citations Open access
Semantic Scholar
Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia
Na Zhao, Wen-Hui Qiao, Fuyao Li, Ying-Xue Ren +27 more
2022Journal of Experimental Medicine93 citations Open access
Semantic Scholar
Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4*
S. J. Spratley, Ligia I. Bastea, Heike R. Döppler, K. Mizuno +1 more
2011Journal of Biological Chemistry72 citations Open access
Semantic Scholar
CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions
Veethika Pandey, Alicia Fleming-Martinez, Ligia I. Bastea, Heike R Doeppler +4 more
2021eLife64 citations Open access
Semantic Scholar
Protein Kinase D1 Maintains the Epithelial Phenotype by Inducing a DNA-Bound, Inactive SNAI1 Transcriptional Repressor Complex
Ligia I. Bastea, Heike R. Döppler, Bolanle Balogun, P. Storz
2012PLoS ONE49 citations Open access
Semantic Scholar
Protein Kinase D Isoforms Differentially Modulate Cofilin-Driven Directed Cell Migration
Heike R. Döppler, Ligia I. Bastea, Sahra Borgés, S. J. Spratley +2 more
2014PLoS ONE41 citations Open access
Semantic Scholar
Protein Kinase D1-mediated Phosphorylations Regulate Vasodilator-stimulated Phosphoprotein (VASP) Localization and Cell Migration*
Heike R. Döppler, Ligia I. Bastea, Laura J. Lewis-Tuffin, P. Anastasiadis +1 more
2013Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Pomalidomide alters pancreatic macrophage populations to generate an immune-responsive environment at precancerous and cancerous lesions
Ligia I. Bastea, Geou-Yarh Liou, Veethika Pandey, Alicia K Fleming +8 more
2019Cancer Research29 citations Open access
Semantic Scholar
Protein Kinase D-mediated phosphorylation at serine 99 regulates localization of p21-activated kinase 4
Ligia I. Bastea, Heike R. Döppler, Sarah E Pearce, N. Durand +2 more
2013Biochemical Journal25 citations Open access
Semantic Scholar
Neuregulin Mediates F-actin-driven Cell Migration through Inhibition of Protein Kinase D1 via Rac1 Protein*
Heike R. Döppler, Ligia I. Bastea, T. Eiseler, P. Storz
2012Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Sangivamycin and its derivatives inhibit Haspin-Histone H3-survivin signaling and induce pancreatic cancer cell death
Ligia I. Bastea, Laeticia Hollant, Heike R. Döppler, Elizabeth M. Reid +1 more
2019Scientific Reports23 citations Open access
Semantic Scholar
The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer
Heike R. Döppler, Richard Panayiotou, Elizabeth M. Reid, Willibroad Maimo +2 more
2016Scientific Reports23 citations Open access
Semantic Scholar
Ym1+ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, B. Edenfield +2 more
2022iScience20 citations Open access
Semantic Scholar
Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells
Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, B. Edenfield +4 more
2021iScience16 citations Open access
Semantic Scholar
The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma
Heike R. Döppler, Ligia I. Bastea, Sahra Borgés, X. Geiger +1 more
2015OncoTarget14 citations Open access
Semantic Scholar
Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ
N. Durand, Ligia I. Bastea, J. Long, Heike R. Döppler +2 more
2016Scientific Reports11 citations Open access
Semantic Scholar
Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
Geou-Yarh Liou, Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea +1 more
2023iScience10 citations Open access
Semantic Scholar
Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion
N. Durand, Ligia I. Bastea, Heike R. Döppler, T. Eiseler +1 more
2017Scientific Reports9 citations Open access
Semantic Scholar
The phosphorylation status of PIP5K1C at serine 448 can be predictive for invasive ductal carcinoma of the breast
N. Durand, Sahra Borgés, Tavia Hall, Ligia I. Bastea +5 more
2018OncoTarget6 citations Open access
Semantic Scholar
Kallikrein related peptidases 7 and 10 and their substrate desmoglein 3 are upregulated in early stage pancreatic cancerous lesions
Jillian Eisenhauer, Ryan A Argo, Alicia K. Fleming Martinez, Emir Maldosevic +7 more
2026Scientific Reports1 citations Open access
Semantic Scholar
Downregulation of Sod2 increases atypical flat lesions and dysplasia to advance pancreatic ductal adenocarcinoma
Alicia K. Fleming Martinez, Heike R. Döppler, Ryan A Argo, Ligia I. Bastea +3 more
2025Molecular Cancer1 citations Open access
Semantic Scholar
A vaccination strategy to prevent coxsackie virus B3-induced development of pancreatic cancer.
Veethika Pandey, Heike R Doeppler, Ligia I. Bastea, Alicia K. Fleming Martinez +5 more
2025JCI Insight0 citations Open access
Semantic Scholar
Coxsackievirus and adenovirus receptor expression facilitates enteroviral infections to drive the development of pancreatic cancer
Ligia I. Bastea, Xiang Liu, Alicia K Fleming, Veethika Pandey +10 more
2024Nature Communications0 citations Open access
Semantic Scholar
Abstract A59: Crosstalk of different macrophage populations with pancreatic acinar or PanIN cells and contribution to development of pancreatic cancer
Geou-Yarh Liou, Heike R Doeppler, Ligia I. Bastea, P. Storz
20160 citations
Semantic Scholar

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Heike R. Döppler×19
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