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Yih-Leong Chang · SciRah

Researcher profile · Semantic Scholar

Yih-Leong Chang

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Yih-Leong Chang — researcher profile on SciRah

h-index: 56
Works: 312
Citations: 11K

Most-cited papers

The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients
Shang-Gin Wu, Yi-Nan Liu, Meng-Feng Tsai, Yih-Leong Chang +5 more
2016OncoTarget238 citations Open access
Semantic Scholar
Identification of a novel FN1–FGFR1 genetic fusion as a frequent event in phosphaturic mesenchymal tumour
Jen-Chieh Lee, Y. Jeng, Sheng-Yao Su, Chen-Tu Wu +12 more
2015Journal of Pathology150 citations
Semantic Scholar
Outcomes in patients with non-small-cell lung cancer and acquired Thr790Met mutation treated with osimertinib: a genomic study.
Chia-Chi Lin, J. Shih, Chong-Jen Yu, Chao-Chi Ho +10 more
2017The Lancet Respiratory Medicine141 citations
Semantic Scholar
M1 macrophages decrease in the deciduae from normal pregnancies but not from spontaneous abortions or unexplained recurrent spontaneous abortions.
Fang-Yu Tsao, Ming-Yih Wu, Yih-Leong Chang, Chen-Tu Wu +1 more
2017Journal of the Formosan Medical Association = Taiwan yi zhi124 citations Open access
Semantic Scholar
A new prognostic histopathologic classification of nasopharyngeal carcinoma
Hai-Yun Wang, Yih-Leong Chang, Ka F. To, J. Hwang +34 more
2016Chinese journal of cancer122 citations Open access
Semantic Scholar
Programmed cell death-ligand 1 expression is associated with a favourable immune microenvironment and better overall survival in stage I pulmonary squamous cell carcinoma.
Ching-Yao Yang, Mong-Wei Lin, Yih-Leong Chang, Chen-Tu Wu +1 more
2016European Journal of Cancer121 citations
Semantic Scholar
High co-expression of PD-L1 and HIF-1α correlates with tumour necrosis in pulmonary pleomorphic carcinoma.
Yih-Leong Chang, Ching-Yao Yang, Mong-Wei Lin, Chen-Tu Wu +1 more
2016European Journal of Cancer110 citations
Semantic Scholar
SOX10-positive salivary gland tumors: a growing list, including mammary analogue secretory carcinoma of the salivary gland, sialoblastoma, low-grade salivary duct carcinoma, basal cell adenoma/adenocarcinoma, and a subgroup of mucoepidermoid carcinoma.
Min-Shu Hsieh, Yi-Hsuan Lee, Yih-Leong Chang
2016Human Pathology110 citations
Semantic Scholar
Analysis of Protein Stability by the Cycloheximide Chase Assay
Shih-Han Kao, Wen-Lung Wang, Chi-Yuan Chen, Yih-Leong Chang +7 more
2015Bio-protocol102 citations Open access
Semantic Scholar
PD-L1 is highly expressed in lung lymphoepithelioma-like carcinoma: A potential rationale for immunotherapy.
Yih-Leong Chang, Ching-Yao Yang, Mong-Wei Lin, Chen-Tu Wu +1 more
2015Lung Cancer99 citations
Semantic Scholar
Association between programmed death-ligand 1 expression, immune microenvironments, and clinical outcomes in epidermal growth factor receptor mutant lung adenocarcinoma patients treated with tyrosine kinase inhibitors.
Ching-Yao Yang, Wei-Yu Liao, Chao-Chi Ho, Kuan-Yu Chen +13 more
2019European Journal of Cancer86 citations
Semantic Scholar
Clinical and the Prognostic Characteristics of Lung Adenocarcinoma Patients with ROS1 Fusion in Comparison with Other Driver Mutations in East Asian Populations
Yen-Fu Chen, Min-Shu Hsieh, Shang-Gin Wu, Yih-Leong Chang +7 more
2014Journal of Thoracic Oncology80 citations Open access
Semantic Scholar
Efficacy of Pemetrexed‐Based Chemotherapy in Patients with ROS1 Fusion–Positive Lung Adenocarcinoma Compared with in Patients Harboring Other Driver Mutations in East Asian Populations
Yen-Fu Chen, Min-Shu Hsieh, Shang-Gin Wu, Yih-Leong Chang +4 more
2016Journal of Thoracic Oncology78 citations Open access
Semantic Scholar
Associations among pretreatment tumor necrosis and the expression of HIF-1α and PD-L1 in advanced oral squamous cell carcinoma and the prognostic impact thereof.
Tseng-Cheng Chen, Chen-Tu Wu, Cheng-Ping Wang, Wan-Lun Hsu +4 more
2015Oral Oncology74 citations
Semantic Scholar
A clinicopathological analysis of 153 acral melanomas and the relevance of mechanical stress
Y. Sheen, Yi-Hua Liao, Ming-Hsien Lin, Jau-Shiuh Chen +5 more
2017Scientific Reports61 citations Open access
Semantic Scholar
Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C.
Tzu-Hua Chang, Meng-Feng Tsai, C. Gow, Shang-Gin Wu +9 more
2017Cancer Letters57 citations
Semantic Scholar
The Role of PIK3CA Mutations among Lung Adenocarcinoma Patients with Primary and Acquired Resistance to EGFR Tyrosine Kinase Inhibition
Shang-Gin Wu, Yih-Leong Chang, Chong-Jen Yu, Pan-Chyr Yang +1 more
2016Scientific Reports56 citations Open access
Semantic Scholar
Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors
Shang-Gin Wu, Yih-Leong Chang, Chong-Jen Yu, Pan-Chyr Yang +1 more
2017ERJ Open Research54 citations Open access
Semantic Scholar
Acquired resistance to EGFR tyrosine kinase inhibitors is mediated by the reactivation of STC2/JUN/AXL signaling in lung cancer
Yi-Nan Liu, Meng-Feng Tsai, Shang-Gin Wu, Tzu-Hua Chang +4 more
2019International Journal of Cancer53 citations Open access
Semantic Scholar
High PD-L1 expression is associated with stage IV disease and poorer overall survival in 186 cases of small cell lung cancers
Yih-Leong Chang, Ching-Yao Yang, Yen-Lin Huang, Chen-Tu Wu +1 more
2017OncoTarget49 citations Open access
Semantic Scholar
Tumor PD-L1 Expression and Clinical Outcomes in Advanced-stage Non-Small Cell Lung Cancer Patients Treated with Nivolumab or Pembrolizumab: Real-World Data in Taiwan
Shu-Yung Lin, Ching-Yao Yang, Bin-Chi Liao, Chao-Chi Ho +12 more
2018Journal of Cancer48 citations Open access
Semantic Scholar
Reevaluation of MAML2 fusion-negative mucoepidermoid carcinoma: a subgroup being actually hyalinizing clear cell carcinoma of the salivary gland with EWSR1 translocation.
Min-Shu Hsieh, Hsu-Ang Wang, Yi-Hsuan Lee, Jenq-Yuh Ko +1 more
2017Human Pathology48 citations
Semantic Scholar
DUSP1 Expression Induced by HDAC1 Inhibition Mediates Gefitinib Sensitivity in Non–Small Cell Lung Cancers
Yun-Tao Lin, Yu-Chin Lin, J. Shih, Wei-Jan Huang +3 more
2015Clinical Cancer Research45 citations
Semantic Scholar
Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Pei-Fang Hung, T. Hong, Che-Chang Chang, Chung-Lieh Hung +8 more
2019Journal of experimental & clinical cancer research : CR44 citations Open access
Semantic Scholar
A Web‐Based Virtual Microscopy Platform for Improving Academic Performance in Histology and Pathology Laboratory Courses: A Pilot Study
Bai-Chin Lee, Sung-Tsang Hsieh, Yih-Leong Chang, Fen-Yu Tseng +7 more
2019Anatomical Sciences Education43 citations
Semantic Scholar
The immunologic advantage of recurrent nasopharyngeal carcinoma from the viewpoint of Galectin-9/Tim-3-related changes in the tumour microenvironment
Tseng-Cheng Chen, Chao-Hsien Chen, Cheng-Ping Wang, Pei-Hsuan Lin +5 more
2017Scientific Reports43 citations Open access
Semantic Scholar
Papillary-cystic pattern is characteristic in mammary analogue secretory carcinomas but is rarely observed in acinic cell carcinomas of the salivary gland
Min-Shu Hsieh, Y. Chou, Shin-Joe Yeh, Yih-Leong Chang
2015Virchows Archiv42 citations
Semantic Scholar
Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference
Ting-Chun Kuo, Kuo-Yen Huang, Shuenn-Chen Yang, Sean Wu +7 more
2020Molecular Therapy: Oncolytics41 citations Open access
Semantic Scholar
Shisa3 is associated with prolonged survival through promoting β-catenin degradation in lung cancer.
Chun-Chieh Chen, Hsuan-Yu Chen, K. Su, Q. Hong +12 more
2014American Journal of Respiratory and Critical Care Medicine39 citations
Semantic Scholar
Regular screening of esophageal cancer for 248 newly diagnosed hypopharyngeal squamous cell carcinoma by unsedated transnasal esophagogastroduodenoscopy.
Yen-Chieh Huang, Yi-Chia Lee, Ping-Huei Tseng, Tseng-Cheng Chen +7 more
2016Oral Oncology36 citations
Semantic Scholar
Circulating mRNA Profiling in Esophageal Squamous Cell Carcinoma Identifies FAM84B As A Biomarker In Predicting Pathological Response to Neoadjuvant Chemoradiation
F. Hsu, Jason Chia-Hsien Cheng, Yih-Leong Chang, Jang-Ming Lee +2 more
2015Scientific Reports32 citations Open access
Semantic Scholar
Rising incidence of HPV positive oropharyngeal cancer in Taiwan between 1999 and 2014 where betel nut chewing is common
Cheng-Ping Wang, Tseng-Cheng Chen, Wan-Lun Hsu, J. Hsiao +9 more
2022BMC Cancer31 citations Open access
Semantic Scholar
Prognostic significance of tumor-infiltrating lymphocytes in patients with operable tongue cancer
Wan-Yu Chen, Chen-Tu Wu, Chun-Wei Wang, Keng-Hsueh Lan +5 more
2018Radiation Oncology30 citations Open access
Semantic Scholar
MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma
Lu-Kai Wang, Szu-Hua Pan, Yih-Leong Chang, Pei-Fang Hung +9 more
2015OncoTarget30 citations Open access
Semantic Scholar
New Aspects of the Clinicopathology and Genetic Profile of Metachronous Multiple Lung Cancers
Chen-Tu Wu, Mong-Wei Lin, Min-Shu Hsieh, Shuenn-Wen Kuo +1 more
2014Annals of Surgery29 citations
Semantic Scholar
Clinical characteristics and treatment outcome of oropharyngeal squamous cell carcinoma in an endemic betel quid region
Tseng-Cheng Chen, Chen-Tu Wu, Jenq-Yuh Ko, Tsung-Lin Yang +3 more
2020Scientific Reports26 citations Open access
Semantic Scholar
Association of Programmed Death-Ligand 1 Expression with Fusion Variants and Clinical Outcomes in Patients with Anaplastic Lymphoma Kinase-Positive Lung Adenocarcinoma Receiving Crizotinib.
Ching-Yao Yang, Wei-Yu Liao, Chao-Chi Ho, Kuan-Yu Chen +14 more
2020The Oncologist25 citations Open access
Semantic Scholar
Impact of dysplastic surgical margins for patients with oral squamous cell carcinoma.
Tseng-Cheng Chen, H. Chang, Tsung-Lin Yang, P. Lou +3 more
2019Oral Oncology25 citations
Semantic Scholar
Vorinostat combined with brigatinib overcomes acquired resistance in EGFR-C797S-mutated lung cancer.
Chia-Yi Lin, Kuo-Yen Huang, Yi-Chun Lin, Shuenn-Chen Yang +9 more
2021Cancer Letters23 citations
Semantic Scholar
BRAF mutation may have different prognostic implications in early- and late-stage colorectal cancer
Kuo-Hsing Chen, Yu-Lin Lin, J. Liau, Jia-Huei Tsai +8 more
2016Medical Oncology23 citations
Semantic Scholar
Histologic Transformation in a Patient with Lung Cancer Treated with Chemotherapy and Pembrolizumab.
Chia-Lin Hsu, Kuan-Yu Chen, Shuenn-Wen Kuo, Yih-Leong Chang
2017Journal of Thoracic Oncology22 citations Open access
Semantic Scholar
IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer
Shang-Gin Wu, Tzu-Hua Chang, Meng-Feng Tsai, Yi-Nan Liu +4 more
2019Cancers21 citations Open access
Semantic Scholar
Clinicopathological features and prognosis of patients with de novo versus nevus-associated melanoma in Taiwan
Y. Sheen, Yi-Hua Liao, Ming-Hsien Lin, Jau-Shiuh Chen +4 more
2017PLoS ONE20 citations Open access
Semantic Scholar
Assessment of D-methionine protecting cisplatin-induced otolith toxicity by vestibular-evoked myogenic potential tests, ATPase activities and oxidative state in guinea pigs.
Wu-Chia Lo, Chih-Ming Chang, Li-Jen Liao, Chi-Te Wang +3 more
2015Neurotoxicology and Teratology20 citations
Semantic Scholar
Lymph Node Ratio Predicts Recurrence and Survival for Patients with Resectable Stage 4 Hypopharyngeal Cancer
Wu-Chia Lo, Chen-Tu Wu, Cheng-Ping Wang, Tsung-Lin Yang +3 more
2017Annals of Surgical Oncology19 citations
Semantic Scholar
Clinicopathology and Genetic Profile of Synchronous Multiple Small Adenocarcinomas: Implication for Surgical Treatment of an Uncommon Lung Malignancy
Mong-Wei Lin, Chen-Tu Wu, Shuenn-Wen Kuo, Yih-Leong Chang +1 more
2014Annals of Surgical Oncology18 citations
Semantic Scholar
Clinical Outcomes of Up-front Surgery Versus Surgery After Induction Chemotherapy for Thymoma and Thymic Carcinoma: A Retrospective Study.
Wei-Li Ma, Chia-Chi Lin, F. Hsu, Jang-Ming Lee +6 more
2019Clinical Lung Cancer17 citations
Semantic Scholar
The Effect of Radiotherapy on Ultrasound-Guided Fine Needle Aspiration Biopsy and the Ultrasound Characteristics of Neck Lymph Nodes in Oral Cancer Patients after Primary Treatment
Wu-Chia Lo, P. Cheng, Chi-Te Wang, P. Shueng +3 more
2016PLoS ONE17 citations Open access
Semantic Scholar
Improved prognosis with induction chemotherapy in pathological complete responders after trimodality treatment for esophageal squamous cell carcinoma: Hypothesis generating for adjuvant treatment.
Shao-Lun Lu, F. Hsu, Chiao-Ling Tsai, Jang-Ming Lee +6 more
2019European Journal of Surgical Oncology16 citations
Semantic Scholar
The Differences in Clinicopathologic and Prognostic Characteristics Between Surgically Resected Peripheral and Central Lung Squamous Cell Carcinoma
Mong-Wei Lin, Yen-Lin Huang, Ching-Yao Yang, Shuenn-Wen Kuo +2 more
2018Annals of Surgical Oncology16 citations
Semantic Scholar

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J. Shih×14
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