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R. Mattson · SciRah

Researcher profile · Semantic Scholar

R. Mattson

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R. Mattson — researcher profile on SciRah

h-index: 18
Works: 87
Citations: 883

Most-cited papers

An improved method for reductive alkylation of amines using titanium(IV) isopropoxide and sodium cyanoborohydride
R. Mattson, K. Pham, David J. Leuck, K. Cowen
1990158 citations
Semantic Scholar
Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde
H. King, Zhaoxing Meng, D. Denhart, R. Mattson +4 more
2005107 citations
Semantic Scholar
A strategy to minimize reactive metabolite formation: discovery of (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a potent, orally bioavailable corticotropin-releasing factor-1 receptor antagonist.
Richard A. Hartz, Vijay T. Ahuja, X. Zhuo, R. Mattson +20 more
2009Journal of Medicinal Chemistry48 citations Open access
Semantic Scholar
Conformationally restricted homotryptamines 3. Indole tetrahydropyridines and cyclohexenylamines as selective serotonin reuptake inhibitors.
J. Deskus, J. Epperson, C. Sloan, J. A. Cipollina +11 more
2007Bioorganic & Medicinal Chemistry Letters35 citations Open access
Semantic Scholar
Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists.
Richard A. Hartz, Vijay T. Ahuja, A. Arvanitis, M. Rafalski +26 more
2009Journal of Medicinal Chemistry33 citations Open access
Semantic Scholar
In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.
Richard A. Hartz, Vijay T. Ahuja, M. Rafalski, W. Schmitz +20 more
2009Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
Aminotriazine 5-HT7 antagonists.
R. Mattson, D. Denhart, J. D. Catt, M. F. Dee +15 more
2004Bioorganic & Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Ortho-directed lithiation in .pi.-deficient diazinyl heterocycles
R. Mattson, C. Sloan
199029 citations
Semantic Scholar
Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors.
D. Denhart, J. Deskus, Jonathan L. Ditta, Qi Gao +10 more
2009Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors.
R. Mattson, J. D. Catt, D. Denhart, J. Deskus +11 more
2005Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Catalytic asymmetric diazoacetate cyclopropanation of 1-tosyl-3-vinylindoles. A route to conformationally restricted homotryptamines.
L. Marcin, D. Denhart, R. Mattson
2005Organic Letters25 citations Open access
Semantic Scholar
Indanyl piperazines as melatonergic MT2 selective agents.
R. Mattson, J. D. Catt, Daniel J. Keavy, C. Sloan +7 more
2003Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
ORTHO-DIRECTED LITHIATION OF 3,4-(ALKYLENEDIOXY)HALOBENZENES WITH LDA AND LITMP. THE FIRST ORTHO LITHIATION OF AN IODOBENZENE
R. Mattson, C. Sloan, C. C. Lockhart, J. D. Catt +2 more
199923 citations
Semantic Scholar
Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs).
W. Schmitz, D. Denhart, Allison B Brenner, Jonathan L. Ditta +4 more
2005Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130.
M. Taber, R. N. Wright, T. Molski, W. Clarke +4 more
2005Pharmacology, Biochemistry and Behavior20 citations
Semantic Scholar
Bivalent indoles exhibiting serotonergic binding affinity
Karen L Leboulluec, R. Mattson, C. D. Mahle, Rachel T. McGovern +2 more
199519 citations
Semantic Scholar
Potential CRF1R PET imaging agents: N-fluoroalkyl-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-alkylpyrazolo[1,5-a][1,3,5]triazin-4-amines.
Dmitry Zuev, R. Mattson, Hong Huang, Gail K. Mattson +9 more
2011Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
SYNTHESIS OF SUBSTITUTED 2-AMINO-3-(ALKYL OR ARYL)SULFONYLPYRROLES
R. Mattson, Li-Chang Wang, J. W. Sowell
198018 citations
Semantic Scholar
Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor.
H. King, D. Denhart, J. Deskus, Jonathan L. Ditta +12 more
2007Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides.
J. Epperson, M. Bruce, J. D. Catt, J. Deskus +10 more
2004Bioorganic & Medicinal Chemistry15 citations
Semantic Scholar
Synthesis and Evaluation of Candidate PET Radioligands for Corticotropin-Releasing Factor Type-1 Receptors
N. Lodge, Yu-wen Li, Frederick T. Chin, D. Dischino +13 more
2014Nuclear Medicine and Biology14 citations Open access
Semantic Scholar
Diaminopyrimidine and diaminopyridine 5-HT7 ligands.
D. Denhart, A. Purandare, J. D. Catt, H. King +7 more
2004Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Development of a presynaptic 5-HT1A antagonist.
R. Mattson, J. D. Catt, C. Sloan, Qi Gao +7 more
2003Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Chapter 4. Agents for the Treatment of Cognitive Disorders
R. Mattson, S. Moon
198811 citations
Semantic Scholar
Regression analysis of post-CHF flow boiling data
R. Mattson, K. Condie, S. Bengston, C. Obenchain
197411 citations
Semantic Scholar
A photographic study of subcooled flow boiling and the boiling crisis in Freon-113
R. Mattson, F. G. Hammitt
197211 citations
Semantic Scholar
Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.
H. King, Zhaoxing Meng, J. Deskus, C. Sloan +10 more
2010Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
Surgical approach to anterior scalenectomy.
R. Mattson
2004Hand Clinics10 citations
Semantic Scholar
Ligand conformation has a definitive effect on 5-HT1A and serotonin reuptake affinity.
Kenneth M. Boy, M. F. Dee, J. Yevich, J. Torrente +4 more
2004Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Synthesis and hSERT activity of homotryptamine analogs. Part 6: [3+2] dipolar cycloaddition of 3-vinylindoles.
L. Marcin, R. Mattson, Qi Gao, Dedong Wu +3 more
2010Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Synthesis of substituted pyrrolo[2,3-D]pyrimidine-2,4-diones
S. R. Etson, R. Mattson, J. Sowell
19798 citations
Semantic Scholar
[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents.
J. Deskus, D. Dischino, R. Mattson, Jonathan L. Ditta +23 more
2012Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Potential CRF1R PET imaging agents: 1-fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones.
D. Denhart, Dmitry Zuev, Jonathan L. Ditta, Richard A. Hartz +10 more
2013Bioorganic & Medicinal Chemistry Letters4 citations Open access
Semantic Scholar
Heterocyclic aminopyrrolidine derivatives as melatoninergic agents.
Li-Qiang Sun, Jie Chen, R. Mattson, J. Epperson +12 more
2004Bioorganic & Medicinal Chemistry Letters4 citations
Semantic Scholar
Statistical regression analysis of experimental data for flow film boiling heat transfer
D. Slaughterbeck, W. Vesely, L. J. Ybarrondo, K. Condie +1 more
19734 citations
Semantic Scholar
Condensation of enolates with O-ethyl pyrrolidonium salts: an alternative to the orthoamide condensation
R. Mattson, J. Sowell, T. Bryson
19853 citations
Semantic Scholar
Conformationally restricted homotryptamines. Part 6: indole-5-cycloalkyl methylamines as selective serotonin reuptake inhibitors.
Jonathan L. Ditta, D. Denhart, J. Deskus, J. Epperson +9 more
2013Bioorganic & Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
Corrections to In Vitro Intrinsic Clearance-Based Optimization of N3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
Richard A. Hartz, Vijay T. Ahuja, M. Rafalski, W. Schmitz +20 more
20092 citations
Semantic Scholar
In vivo disposition and in vitro metabolism of an anxiolytic compound, BMS-184111, in rats.
Krishnasway Yeleswaram, K. Volk, R. Rourick, J. D. Catt +3 more
1995Research Communications in Molecular Pathology and Pharmacology2 citations
Semantic Scholar
Bivalent Indoles Exhibiting Serotonergic Binding Affinity.
Karen L Leboulluec, R. Mattson, C. D. Mahle, Rachel T. McGovern +2 more
19952 citations
Semantic Scholar
Evaluation of 99mTc-labeled iminodiacetic acid derivatives of substituted 2-aminopyrroles as hepatobiliary imaging agents in rats II.
Bernard W. Graham, Carl M. Dejuliis, R. Mattson, J. Sowell
1980Journal of Pharmacy and Science2 citations
Semantic Scholar
A new product concept for improvement of industrial waters.
W. T. Robinson, R. Mattson
1968Journal - Water Pollution Control Federation2 citations
Semantic Scholar
Synthesis of radio‐iodinated melatonergic agents
D. Dischino, R. Mattson, M. Ogan, Michael F. Parker +1 more
20021 citations
Semantic Scholar
ortho‐Directed Lithiation of 3,4‐(Alkylenedioxy)halobenzens with LDA and LiTMP. The First ortho Lithiation of an Iodobenzene.
R. Mattson, C. Sloan, C. C. Lockhart, J. D. Catt +2 more
20001 citations
Semantic Scholar
SYNTHESIS OF SUBSTITUTED PYRROLO(2,3-D)PYRIMIDINE-2,4-DIONES
S. R. Etson, R. Mattson, J. W. Sen. Sowell
19801 citations
Semantic Scholar
" Alleviation of Jet Lag by Melatonin : Pre liminary Results of Controlled Double Blind Trial
Dervatives AS Melatonergics, R. Mattson, G. Johnson
20170 citations
Semantic Scholar
Synthesis and hSERT Activity of Homotryptamine Analogues. Part 6. [3 + 2] Dipolar Cycloaddition of 3-Vinylindoles.
L. Marcin, R. Mattson, Qi Gao, Dedong Wu +3 more
20100 citations Open access
Semantic Scholar
Synthesis of BMS-594726
H. King, Zhaoxing Meng, D. Denhart, R. Mattson +4 more
20060 citations
Semantic Scholar
Enantioselective synthesis of a highly potent selective serotonin reuptake inhibitor. An application of imidazolidinone catalysis to the alkylation of indoles with an alpha,beta-disubstituted alpha,beta-unsaturated aldehyde.
H. King, Zhaoxing Meng, D. Denhart, R. Mattson +4 more
2005Organic Letters0 citations
Semantic Scholar
Development of a Presynaptic 5-HT1A Antagonist (I).
R. Mattson
20030 citations
Semantic Scholar

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