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R. Westrick · SciRah

Researcher profile · Semantic Scholar

R. Westrick

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R. Westrick — researcher profile on SciRah

h-index: 26
Works: 71
Citations: 3,656

Most-cited papers

Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators.
J. M. Park, F. Greten, A. Wong, R. Westrick +5 more
2005Immunity344 citations Open access
Semantic Scholar
Plasminogen Activator Inhibitor-1 Regulates Tumor Growth and Angiogenesis*
G. McMahon, E. Petitclerc, S. Stefansson, Elizabeth Smith +5 more
2001Journal of Biological Chemistry289 citations Open access
Semantic Scholar
Effect of leptin on arterial thrombosis following vascular injury in mice.
P. Bodary, R. Westrick, K. Wickenheiser, Yuechen Shen +1 more
2002Journal of the American Medical Association (JAMA)246 citations
Semantic Scholar
Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice
Yanling Zhang, S. Zolov, Clement Y. Chow, S. G. Slutsky +8 more
2007Proceedings of the National Academy of Sciences of the United States of America237 citations Open access
Semantic Scholar
Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery.
D. Eitzman, R. Westrick, Zuojun Xu, Julia Tyson +1 more
2000Blood209 citations
Semantic Scholar
Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice.
D. Eitzman, R. Westrick, E. G. Nabel, David Ginsburg
2000Blood199 citations
Semantic Scholar
Murine Models of Vascular Thrombosis
R. Westrick, M. Winn, D. Eitzman
2007168 citations Open access
Semantic Scholar
Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase.
K. Mohlke, Anjali A. Purkayastha, R. Westrick, Peter L. R. Smith +3 more
1999Cell166 citations Open access
Semantic Scholar
Heme Oxygenase-1 Deficiency Accelerates Formation of Arterial Thrombosis Through Oxidative Damage to the Endothelium, Which Is Rescued by Inhaled Carbon Monoxide
A. True, M. Olive, M. Boehm, San Hong +8 more
2007Circulation Research163 citations Open access
Semantic Scholar
Deficiency of Tissue Factor Pathway Inhibitor Promotes Atherosclerosis and Thrombosis in Mice
R. Westrick, P. Bodary, Zuojun Xu, Yue-Chun Shen +2 more
2001Circulation161 citations Open access
Semantic Scholar
Spontaneous thrombosis in mice carrying the factor V Leiden mutation.
Jisong Cui, D. Eitzman, R. Westrick, P. D. Christie +9 more
2000Blood153 citations
Semantic Scholar
Heparin cofactor II inhibits arterial thrombosis after endothelial injury.
Li He, C. P. Vicente, R. Westrick, D. Eitzman +1 more
2002Journal of Clinical Investigation143 citations Open access
Semantic Scholar
The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival.
Kristiann M. Dougherty, Julia M. Pearson, A. Yang, R. Westrick +2 more
1999Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
Murine models of vascular thrombosis (Eitzman series).
R. Westrick, M. Winn, D. Eitzman
2007Arteriosclerosis, Thrombosis and Vascular Biology108 citations
Semantic Scholar
Atherosclerosis progression in LDL receptor-deficient and apolipoprotein E-deficient mice is independent of genetic alterations in plasminogen activator inhibitor-1.
H. Sjöland, D. Eitzman, David Gordon, R. Westrick +2 more
2000Arteriosclerosis, Thrombosis and Vascular Biology99 citations Open access
Semantic Scholar
Hyperlipidemia promotes thrombosis after injury to atherosclerotic vessels in apolipoprotein E-deficient mice.
D. Eitzman, R. Westrick, Zuo-Jun J. Xu, Julia Tyson +1 more
2000Arteriosclerosis, Thrombosis and Vascular Biology98 citations Open access
Semantic Scholar
Lethal Perinatal Thrombosis in Mice Resulting From the Interaction of Tissue Factor Pathway Inhibitor Deficiency and Factor V Leiden
D. Eitzman, R. Westrick, Xiao-Ming Bi, Sara L. Manning +3 more
2002Circulation86 citations Open access
Semantic Scholar
Plasminogen activator inhibitor-1 in vascular thrombosis.
R. Westrick, D. Eitzman
2007Current Drug Targets77 citations
Semantic Scholar
Homozygosity for Factor V Leiden Leads to Enhanced Thrombosis and Atherosclerosis in Mice
D. Eitzman, R. Westrick, Yue-Chun Shen, P. Bodary +4 more
2005Circulation73 citations Open access
Semantic Scholar
A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.
K. Mohlke, William C. Nichols, R. Westrick, Edward K. Novak +3 more
1996Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Fatal hemorrhage in mice lacking γ-glutamyl carboxylase
A. Zhu, Hong-Min Sun, R. M. Raymond, B. Furie +5 more
200758 citations Open access
Semantic Scholar
The Glycocalyx Protects Erythrocyte-Bound Tissue-Type Plasminogen Activator from Enzymatic Inhibition
K. Ganguly, J. Murciano, R. Westrick, J. Leferovich +2 more
2007Journal of Pharmacology and Experimental Therapeutics51 citations
Semantic Scholar
Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
R. Sood, M. Zogg, R. Westrick, Yi-He Guo +5 more
2007Journal of Experimental Medicine48 citations Open access
Semantic Scholar
Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase.
A. Zhu, Hong-Min Sun, R. Raymond, B. Furie +5 more
2007Blood33 citations
Semantic Scholar
The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele
J. Johnsen, G. Levy, R. Westrick, P. Tucker +1 more
2008Mammalian Genome28 citations Open access
Semantic Scholar
Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele
R. Westrick, K. Mohlke, Lindsey M. Korepta, A. Yang +5 more
2010Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Modifier genes for disorders of thrombosis and hemostasis
R. Westrick, D. Ginsburg
2009Journal of Thrombosis and Haemostasis21 citations Open access
Semantic Scholar
Pulmonary Fibrosis Is Increased in Mice Carrying the Factor V Leiden Mutation following Bleomycin Injury
Zuo-Jun J. Xu, R. Westrick, Yue-Chun Shen, D. Eitzman
2001Thrombosis and Haemostasis21 citations
Semantic Scholar
A coagulation defect arising from heterozygous premature termination of tissue factor.
S. Schulman, Emale El-Darzi, Mary H. C. Florido, M. Friesen +13 more
2020Journal of Clinical Investigation18 citations Open access
Semantic Scholar
Tissue factor pathway inhibitor is required for cerebrovascular development in mice.
S. Maroney, R. Westrick, A. Cleuren, Nicholas D. Martinez +5 more
2020Blood16 citations Open access
Semantic Scholar
Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth
R. Westrick, Lisa Payne Røjkjær, A. Yang, M. Roh +2 more
2020Journal of Thrombosis and Haemostasis16 citations Open access
Semantic Scholar
Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci
R. Westrick, Kärt Tomberg, Amy E. Siebert, Guo-Jing Zhu +14 more
2017Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
Thrombus stability explains the factor V Leiden paradox: a mouse model.
S. Shaya, R. Westrick, Peter L. Gross
2019Blood Advances12 citations Open access
Semantic Scholar
Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.
K. Mohlke, Anjali A. Purkayastha, R. Westrick, D. Ginsburg
1998Genomics12 citations
Semantic Scholar
Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice
Kärt Tomberg, R. Khoriaty, R. Westrick, H. Fairfield +5 more
2016PLoS ONE11 citations Open access
Semantic Scholar
Intratumoural haematopoietic stem and progenitor cell differentiation into M2 macrophages facilitates the regrowth of solid tumours after radiation therapy
Tyler M. Parsons, K. Buelow, Alaa Hanna, Marisa A. Brake +6 more
2021British Journal of Cancer8 citations Open access
Semantic Scholar
Platelets: context dependent vascular protectors or mediators of disease
R. Westrick, G. Fredman
2015Arteriosclerosis, Thrombosis and Vascular Biology8 citations Open access
Semantic Scholar
Vascular Photochemical Injury in the Mouse
D. Eitzman, R. Westrick
20017 citations Open access
Semantic Scholar
Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse
Kärt Tomberg, R. Westrick, E. Kotnik, D. Siemieniak +4 more
2017bioRxiv6 citations Open access
Semantic Scholar
Genetic Analysis of Human RNA Binding Motif Protein 48 (RBM48) Reveals an Essential Role in U12-Type Intron Splicing.
Amy E. Siebert, Jacob Corll, J. P. Gronevelt, L. Levine +10 more
2022Genetics5 citations Open access
Semantic Scholar
atherosclerosis progression in the mouse carotid artery Plasminogen activator inhibitor-1 deficiency protects against
D. Eitzman, R. Westrick, Zuo-Jun J. Xu, Julia Tyson +1 more
20105 citations
Semantic Scholar
A Sensitized Genome-Wide ENU Mutagenesis Screen in the Mouse to Identify Genetic Modifiers of Thrombosis.
R. Westrick, Sara L. Manning, Sarah L. Dobies, A. Peterson +3 more
20045 citations
Semantic Scholar
Identification of Genomic Loci Regulating Platelet Plasminogen Activator Inhibitor-1 in Mice
Amy E. Siebert, Marisa A. Brake, S. Verbeek, Alexander J. Johnston +12 more
2023Journal of Thrombosis and Haemostasis3 citations
Semantic Scholar
1064-182 Gene transfer of an ApoA-I mimetic peptide reduces atherosclerosis in mice
P. Bodary, Yue-Chun Shen, R. Westrick, N. Lalwani +3 more
20043 citations Open access
Semantic Scholar
The factor V Leiden mutation results in the in vivo loss of a critical FV anticoagulant function
R. Westrick, Hong-Min Sun, D. Eitzman, Sara L. Manning +4 more
20033 citations Open access
Semantic Scholar
Evolutionary Conservation and Essential Function of Human and Maize RNA Binding Motif Protein 48 (RBM48) in U12-Type Intron Splicing
Amy E. Siebert, Jacob Corll, J. Paige Gronevelt, L. Levine +8 more
2020bioRxiv2 citations Open access
Semantic Scholar
Identification of Regulatory Loci for Megakaryocyte and Hepatocyte Coagulation Factor V Expression in Mice
Adrianna M. Jurek, Kailey MacFadyen, Marisa A. Brake, L. Ivanciu +2 more
2025bioRxiv1 citations Open access
Semantic Scholar
Whole-Exome Sequencing to Identify Mutations in Thrombosis Modifier Genes Isolated From a Factor V Leiden-Dependent Sensitized ENU Suppressor Screen in the Mouse
R. Westrick, Guo-Jing Zhu, Ji-Shu Xu, A. Cleuren +6 more
20111 citations
Semantic Scholar
A Sensitized ENU Mutagenesis Screen for Thrombosis Modifiers Identifies Suppressor Variants in Non-mutagenized Parental Generations Due to Antithrombotic Selective Pressures
Marisa A. Brake, A. Cleuren, S. Torres, M. van der Ent +11 more
2026bioRxiv0 citations
Semantic Scholar
PB3121 Identification of Significant Sex Specific F5 Expression Differences in Mice
Adrianna Richards, Kailey MacFadyen, Caitlin Schneider, Marisa Brake +2 more
2026Research and Practice in Thrombosis and Haemostasis0 citations Open access
Semantic Scholar

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