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G. Fredman · SciRah

Researcher profile · Semantic Scholar

G. Fredman

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G. Fredman — researcher profile on SciRah

h-index: 37
Works: 73
Citations: 7,747

Most-cited papers

Infection Regulates Pro-Resolving Mediators that Lower Antibiotic Requirements
N. Chiang, G. Fredman, F. Bäckhed, Sungwhan F. Oh +3 more
2012Nature658 citations Open access
Semantic Scholar
Inflammation and its resolution as determinants of acute coronary syndromes
P. Libby, I. Tabas, G. Fredman, E. Fisher
2014Circulation Research490 citations Open access
Semantic Scholar
An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques
G. Fredman, Jason Hellmann, J. Proto, G. Kuriakose +8 more
2016Nature Communications390 citations Open access
Semantic Scholar
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
A. Ariel, G. Fredman, Yee-Ping Sun, A. Kantarcı +3 more
2006Nature Immunology378 citations Open access
Semantic Scholar
Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice
G. Fredman, N. Kamaly, Stefano Spolitu, Jaclyn Milton +6 more
2015Science Translational Medicine339 citations Open access
Semantic Scholar
MicroRNAs in resolution of acute inflammation: identification of novel resolvin Dl‐miRNA circuits
A. Recchiuti, S. Krishnamoorthy, G. Fredman, N. Chiang +1 more
2011The FASEB Journal315 citations Open access
Semantic Scholar
Resolvin D Series and Protectin D1 Mitigate Acute Kidney Injury1
J. Duffield, Song Hong, V. Vaidya, Yan Lu +3 more
2006Journal of Immunology311 citations Open access
Semantic Scholar
Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.
Giovanna Leoni, P. Neumann, N. Kamaly, Miguel Quirós +15 more
2015Journal of Clinical Investigation306 citations Open access
Semantic Scholar
Mechanisms and Consequences of Defective Efferocytosis in Atherosclerosis
Arif Yurdagul, Amanda C. Doran, Bi-Shuang Cai, G. Fredman +1 more
2018Frontiers in Cardiovascular Medicine277 citations Open access
Semantic Scholar
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.
S. Krishnamoorthy, A. Recchiuti, N. Chiang, G. Fredman +1 more
2012American Journal of Pathology275 citations Open access
Semantic Scholar
The Docosatriene Protectin D1 Is Produced by TH2 Skewing and Promotes Human T Cell Apoptosis via Lipid Raft Clustering*
A. Ariel, Pin Li, Wei Wang, Wang-Xian Tang +4 more
2005Journal of Biological Chemistry255 citations Open access
Semantic Scholar
Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets.
M. Donà, G. Fredman, J. Schwab, N. Chiang +5 more
2008Blood241 citations Open access
Semantic Scholar
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
Bi-Shuang Cai, E. Thorp, Amanda C. Doran, Manikandan Subramanian +5 more
2016Proceedings of the National Academy of Sciences of the United States of America232 citations Open access
Semantic Scholar
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis
Bi-Shuang Cai, E. Thorp, Amanda C. Doran, Brian E. Sansbury +5 more
2017Journal of Clinical Investigation229 citations Open access
Semantic Scholar
Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis
N. Kamaly, G. Fredman, Jhalique Jane R. Fojas, Manikandan Subramanian +15 more
2016ACS Nano208 citations Open access
Semantic Scholar
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles
N. Kamaly, G. Fredman, Manikandan Subramanian, Suresh Gadde +6 more
2013Proceedings of the National Academy of Sciences of the United States of America200 citations Open access
Semantic Scholar
Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway
G. Fredman, L. Ozcan, Stefano Spolitu, Jason Hellmann +3 more
2014Proceedings of the National Academy of Sciences of the United States of America191 citations Open access
Semantic Scholar
Resolvin E2 formation and impact in inflammation-resolution
Sungwhan F. Oh, M. Donà, G. Fredman, S. Krishnamoorthy +2 more
2012Journal of Immunology185 citations Open access
Semantic Scholar
Boosting Inflammation Resolution in Atherosclerosis: The Next Frontier for Therapy.
G. Fredman, I. Tabas
2017American Journal of Pathology176 citations Open access
Semantic Scholar
Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution
G. Fredman, C. N. Serhan
2011Biochemical Journal166 citations Open access
Semantic Scholar
Novel Pro-resolving Aspirin-Triggered DHA Pathway
C. Serhan, G. Fredman, Rong Yang, S. Karamnov +5 more
2011Chemistry and Biology163 citations Open access
Semantic Scholar
Impaired Phagocytosis in Localized Aggressive Periodontitis: Rescue by Resolvin E1
G. Fredman, Sungwhan F. Oh, S. Ayilavarapu, H. Hasturk +2 more
2011PLoS ONE158 citations Open access
Semantic Scholar
Self-Limited versus Delayed Resolution of Acute Inflammation: Temporal Regulation of Pro-Resolving Mediators and MicroRNA
G. Fredman, Yongsheng Li, Jesmond Dalli, Nan Chiang +1 more
2012Scientific Reports126 citations Open access
Semantic Scholar
Resolvin E1 and Chemokine-like Receptor 1 ChemR23 Mediate Bone Preservation
Li Gao, D. Faibish, G. Fredman, B. Herrera +4 more
2012Journal of Immunology121 citations Open access
Semantic Scholar
Novel aspirin-triggered Neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke
N. Bazan, Tiffany N. Eady, Larissa Khoutorova, Kristal D. Atkins +11 more
2012Experimental Neurology118 citations Open access
Semantic Scholar
Resolvin D1 promotes the targeting and clearance of necroptotic cells
Brennan D. Gerlach, Michael Marinello, J. Heinz, Nicholas Rymut +11 more
2019Cell Death and Differentiation117 citations Open access
Semantic Scholar
Anesthetics Impact the Resolution of Inflammation
N. Chiang, J. Schwab, G. Fredman, K. Kasuga +2 more
2008PLoS ONE111 citations Open access
Semantic Scholar
CAMKII&ggr; suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis
Amanda C. Doran, L. Ozcan, Bi-Shuang Cai, Ze Zheng +8 more
2017Journal of Clinical Investigation103 citations Open access
Semantic Scholar
Resolvin E1 Regulates ADP Activation of Human Platelets
G. Fredman, T. Van Dyke, Charles N. Serhan
2010Arteriosclerosis, Thrombosis and Vascular Biology102 citations Open access
Semantic Scholar
Resolvin D1 promotes efferocytosis in aging by limiting senescent cell-induced MerTK cleavage
Nicholas Rymut, J. Heinz, Sudeshna Sadhu, Zeinab F. Hosseini +6 more
2019The FASEB Journal97 citations Open access
Semantic Scholar
Specialized pro-resolving mediators in cardiovascular diseases
G. Fredman, Matthew Spite
2017Molecular Aspects of Medicine85 citations Open access
Semantic Scholar
Decoding Functional Metabolomics with Docosahexaenoyl Ethanolamide (DHEA) Identifies Novel Bioactive Signals*
Rong Yang, G. Fredman, S. Krishnamoorthy, Nitin Agrawal +3 more
2011Journal of Biological Chemistry85 citations Open access
Semantic Scholar
Diabetes-Induced Oxidative Stress Is Mediated by Ca2+-Independent Phospholipase A2 in Neutrophils
S. Ayilavarapu, A. Kantarcı, G. Fredman, Oya Turkoglu +6 more
2010Journal of Immunology83 citations Open access
Semantic Scholar
Resolvin D1 enhances necroptotic cell clearance through promoting macrophage fatty acid oxidation and oxidative phosphorylation
Zeinab F. Hosseini, Michael Marinello, Christa Decker, Brian E. Sansbury +6 more
2021Arteriosclerosis, Thrombosis and Vascular Biology68 citations Open access
Semantic Scholar
Atherosclerosis is a Major Human Killer and Non-resolving Inflammation is a Prime Suspect.
G. Fredman, K. MacNamara
2021Cardiovascular Research45 citations Open access
Semantic Scholar
Radiation-induced macrophage senescence impairs resolution programs and drives cardiovascular inflammation
Sudeshna Sadhu, Christa Decker, Brian E. Sansbury, Michael Marinello +12 more
2021Journal of Immunology42 citations Open access
Semantic Scholar
Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.
Canan Kasikara, M. Schilperoort, Brennan D. Gerlach, Chenyi Xue +9 more
2021Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice
Nina Martino, R. B. Ramos, Shu-Han Lu, K. Leyden +6 more
2020bioRxiv33 citations Open access
Semantic Scholar
Pro-Resolving Ligands Orchestrate Phagocytosis
Christa Decker, Sudeshna Sadhu, G. Fredman
2021Frontiers in Immunology24 citations Open access
Semantic Scholar
Recent advances in the role of immunity in atherosclerosis.
G. Fredman, Matthew Spite
2013Circulation Research23 citations Open access
Semantic Scholar
Can Inflammation-Resolution Provide Clues to Treat Patients According to Their Plaque Phenotype?
G. Fredman
2019Frontiers in Pharmacology19 citations Open access
Semantic Scholar
Common Therapeutic Targets in Cardiometabolic Disease
G. Fredman, L. Ozcan, I. Tabas
2014Science Translational Medicine18 citations Open access
Semantic Scholar
Sex differences in the effects of high fat diet on underlying neuropathology in a mouse model of VCID
Charly Abi-Ghanem, A. Salinero, David Kordit, F. Mansour +11 more
2023Biology of Sex Differences17 citations Open access
Semantic Scholar
DELineating resolution of inflammation
G. Fredman
2018Nature Immunology17 citations
Semantic Scholar
Resolving atherosclerosis and Alzheimer disease
G. Fredman
2019Nature Reviews Cardiology16 citations
Semantic Scholar
Pro-resolution therapeutics for cardiovascular diseases.
J. Heinz, Michael Marinello, G. Fredman
2017Prostaglandins & other lipid mediators15 citations
Semantic Scholar
IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock
J. Howard, Julianne N. P. Smith, G. Fredman, K. MacNamara
2021Stem Cell Reports12 citations Open access
Semantic Scholar
Insights into the role of the resolvin D2-GPR18 signaling axis in cardiovascular physiology and disease.
Matthew Spite, G. Fredman
2023Advances in Pharmacology11 citations
Semantic Scholar
The inflamed sputum in lower respiratory tract infection: l‐lactate levels are correlated to neutrophil accumulation
G. Fredman, M. Kolpen, F. B. Hertz, P. T. Petersen +5 more
2019Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)11 citations Open access
Semantic Scholar
Devouring atherosclerotic plaques
G. Fredman
2020Nature Nanotechnology10 citations
Semantic Scholar

Frequent co-authors

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C. Serhan×14
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C. Serhan — researcher profile on SciRah
I. Tabas×13
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I. Tabas — researcher profile on SciRah
Matthew Spite×11
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Matthew Spite — researcher profile on SciRah
N. Chiang×6
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N. Chiang — researcher profile on SciRah

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Sudeshna Sadhu — researcher profile on SciRah

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T. Van Dyke — researcher profile on SciRah

Brian E. Sansbury×5

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Brian E. Sansbury — researcher profile on SciRah

Michael Marinello×5

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Michael Marinello — researcher profile on SciRah

G. Kuriakose×4

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G. Kuriakose — researcher profile on SciRah

B. Dorweiler×4

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B. Dorweiler — researcher profile on SciRah

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N. Kamaly — researcher profile on SciRah

S. Krishnamoorthy×4

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S. Krishnamoorthy — researcher profile on SciRah