Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

F. Cattaruzza · SciRah

Researcher profile · Semantic Scholar

F. Cattaruzza

Share profile

F. Cattaruzza — researcher profile on SciRah

h-index: 21
Works: 66
Citations: 2,242

Most-cited papers

The TGR5 receptor mediates bile acid-induced itch and analgesia.
F. Alemi, Edwin Kwon, D. Poole, T. Lieu +14 more
2013Journal of Clinical Investigation357 citations Open access
Semantic Scholar
THE RECEPTOR TGR5 MEDIATES THE PROKINETIC ACTIONS OF INTESTINAL BILE ACIDS AND IS REQUIRED FOR NORMAL DEFECATION IN MICE
F. Alemi, D. Poole, Jonathan Chiu, K. Schoonjans +4 more
2012Gastroenterology343 citations Open access
Semantic Scholar
EXPRESSION AND FUNCTION OF THE BILE ACID RECEPTOR GPBAR1 (TGR5) IN THE MURINE ENTERIC NERVOUS SYSTEM
D. Poole, Cody B. Godfrey, F. Cattaruzza, G. Cottrell +4 more
2010Neurogastroenterology and Motility210 citations Open access
Semantic Scholar
WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death
M. Fischer, B. Cancilla, V. P. Yeung, F. Cattaruzza +13 more
2017Science Advances133 citations Open access
Semantic Scholar
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.
F. Cattaruzza, I. Spreadbury, M. Miranda-Morales, E. Grady +2 more
2010American Journal of Physiology - Gastrointestinal and Liver Physiology126 citations Open access
Semantic Scholar
Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice.
E. Ceppa, F. Cattaruzza, Victoria Lyo, S. Amadesi +8 more
2010American Journal of Physiology - Gastrointestinal and Liver Physiology101 citations Open access
Semantic Scholar
Cathepsin S is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-dependent Mechanism in Mice
F. Cattaruzza, Victoria Lyo, E. Jones, David Pham +7 more
2011Gastroenterology99 citations Open access
Semantic Scholar
Precision-activated T-cell engagers targeting HER2 or EGFR and CD3 mitigate on-target, off-tumor toxicity for immunotherapy in solid tumors
F. Cattaruzza, A. Nazeer, Milton To, M. Hammond +13 more
2023Nature Cancer86 citations Open access
Semantic Scholar
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
D. Poole, J. Pelayo, F. Cattaruzza, Y. Kuo +6 more
2011Gastroenterology85 citations Open access
Semantic Scholar
Brain-gut interactions increase peripheral nociceptive signaling in mice with postinfectious irritable bowel syndrome.
Charles Ibeakanma, F. Ochoa-Cortes, M. Miranda-Morales, T. Mcdonald +8 more
2011Gastroenterology84 citations Open access
Semantic Scholar
Pungent General Anesthetics Activate Transient Receptor Potential-A1 to Produce Hyperalgesia and Neurogenic Bronchoconstriction
Helge Eilers, F. Cattaruzza, R. Nassini, S. Materazzi +6 more
2010Anesthesiology64 citations Open access
Semantic Scholar
Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents.
F. Cattaruzza, N. Cenac, E. Barocelli, M. Impicciatore +3 more
2006American Journal of Pathology62 citations Open access
Semantic Scholar
Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice.
F. Cattaruzza, Cali Johnson, Alan Leggit, E. Grady +9 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology55 citations Open access
Semantic Scholar
The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice.
E. Barocelli, V. Ballabeni, P. Ghizzardi, F. Cattaruzza +3 more
2006Nitric oxide52 citations
Semantic Scholar
RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations
Marcus M. Fischer, V. P. Yeung, F. Cattaruzza, Rajaa A. Hussein +10 more
2017Scientific Reports51 citations Open access
Semantic Scholar
Active cathepsins B, L, and S in murine and human pancreatitis.
Victoria Lyo, F. Cattaruzza, Tyson N. Kim, Austin W. Walker +9 more
2012American Journal of Physiology - Gastrointestinal and Liver Physiology41 citations Open access
Semantic Scholar
Serine proteases mediate inflammatory pain in acute pancreatitis.
E. Ceppa, Victoria Lyo, E. Grady, W. Knecht +5 more
2011American Journal of Physiology - Gastrointestinal and Liver Physiology41 citations Open access
Semantic Scholar
Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography
M. J. Page, A. Lourenço, Tovo David, Aaron M. LeBeau +5 more
2015Nature Communications38 citations Open access
Semantic Scholar
Endothelin‐converting enzyme 1 promotes re‐sensitization of neurokinin 1 receptor‐dependent neurogenic inflammation
F. Cattaruzza, G. Cottrell, N. Vaksman, N. Bunnett
2009British Journal of Pharmacology35 citations Open access
Semantic Scholar
Serine proteases and protease‐activated receptor 2 mediate the proinflammatory and algesic actions of diverse stimulants
F. Cattaruzza, S. Amadesi, Johan F. Carlsson, Jane E. Murphy +6 more
2014British Journal of Pharmacology31 citations Open access
Semantic Scholar
Endothelin-converting Enzyme 1 and β-Arrestins Exert Spatiotemporal Control of Substance P-induced Inflammatory Signals*
D. Jensen, M. Halls, Jane E. Murphy, M. Canals +6 more
2014Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Phase 1b study of WNT inhibitor vantictumab (VAN, human monoclonal antibody) with nab-paclitaxel (Nab-P) and gemcitabine (G) in patients (pts) with previously untreated stage IV pancreatic cancer (PC)
W. Messersmith, S. J. Cohen, S. Shahda, H. Lenz +14 more
201620 citations Open access
Semantic Scholar
Phase Ib: Preliminary clinical activity and immune activation for NKTR-262 [TLR 7/8 agonist] plus NKTR-214 [CD122-biased agonist] in patients (pts) with locally advanced or metastatic solid tumors (REVEAL Phase Ib/II Trial).
A. Diab, M. Marcondes, B. Kotzin, M. Tagliaferri +13 more
2019Journal of Clinical Oncology16 citations
Semantic Scholar
Arresting inflammation: contributions of plasma membrane and endosomal signalling to neuropeptide-driven inflammatory disease.
F. Cattaruzza, D. Poole, N. Bunnett
2013Biochemical Society Transactions15 citations
Semantic Scholar
Phase 1b of WNT inhibitor ipafricept (IPA, decoy receptor for WNT ligands) with carboplatin (C) and paclitaxel (P) in recurrent platinum-sensitive ovarian cancer (OC).
R. O'Cearbhaill, D. Mcmeekin, G. Mantia-Smaldone, C. Gunderson +9 more
201614 citations
Semantic Scholar
Evidence for the involvement of 5-HT2A receptors in mild mesenteric ischemia/reperfusion dysfunctions in mice.
S. Bertoni, P. Ghizzardi, F. Cattaruzza, V. Ballabeni +4 more
2007Pharmacological Research13 citations
Semantic Scholar
Abstract 3376: HER2-XPAT and EGFR-XPAT: Pro-drug T-cell engagers (TCEs) engineered to address on-target, off-tumor toxicity with potent efficacy in vitro and in vivo and large safety margins in NHP
F. Cattaruzza, A. Nazeer, Z. Lange, M. Hammond +5 more
2020Immunology7 citations
Semantic Scholar
Abstract 4233: Wnt pathway antagonist ipafricept (FZD8-Fc, OMP-54F28) inhibits tumor growth and reduces tumor-initiating cell frequency in ovarian patient-derived xenograft models
M. Fischer, W. Yen, Chunhua Zheng, Randall Henner +8 more
20156 citations
Semantic Scholar
Abstract 5627: Anti-TIGIT biomarker study: Inhibition of TIGIT induces loss of Tregs from tumors and requires effector function for tumor growth inhibition
G. Argast, B. Cancilla, F. Cattaruzza, P. Yeung +15 more
2018Clinical research5 citations
Semantic Scholar
Abstract P193: AMX-818, a novel prodrug HER2-XPAT T-cell engager (TCE) with potent T cell activation, proteolytic cleavage and efficacy in xenograft tumors, and wide safety margins in NHP (Non Human Primate)
Milton To, P. Yeung, Michael Fox, M. Hammond +13 more
2021Poster Presentations - Proffered Abstracts3 citations
Semantic Scholar
Abstract 599: Pharmacodynamic biomarkers for anti-TIGIT treatment and prevalence of TIGIT expression in multiple solid tumor types
F. Cattaruzza, P. Yeung, Min Wang, A. Brunner +10 more
20173 citations
Semantic Scholar
Abstract 4652: Effects of anti-DLL4 treatment on non-small cell lung cancer (NSCLC) human xenograft tumors
A. Brunner, F. Cattaruzza, W. Yen, P. Yeung +10 more
20163 citations
Semantic Scholar
Abstract 3129: Predictive biomarker identification for response to vantictumab (OMP-18R5; anti-Frizzled) using primary patient-derived human pancreatic tumor xenografts
Chun Zhang, F. Cattaruzza, P. Yeung, W. Yen +10 more
20163 citations
Semantic Scholar
512 The Transient Receptor Potential (Trp) Ion Channels TRPA1 and TRPV4 Mediate Inflammatory Pain in the Pancreas
E. Ceppa, F. Cattaruzza, S. Amadesi, N. Vaksman +4 more
20083 citations
Semantic Scholar
Abstract A030: Biomarker study of vantictumab plus paclitaxel in HER2- breast cancer patients
Chun Zhang, W. Henner, Min Wang, F. Cattaruzza +8 more
20182 citations
Semantic Scholar
Rational combination therapy in young vs older patients with advanced colorectal cancer (CRC).
A. Capasso, T. Pitts, J. Tentler, P. Klauck +8 more
20172 citations
Semantic Scholar
Abstract 404: Development of a RSPO3 CLIA-validated assay as a predictive biomarker for response to anti-RSPO3 antibody treatment in patients with solid tumors
Chun Zhang, Yu-Wang Liu, Min Wang, G. O'young +15 more
20162 citations
Semantic Scholar
Abstract 4367: Discovery and evaluation of pharmacodynamic and predictive biomarkers for anti-RSPO3, a treatment that reduces tumor growth and cancer stem cell frequency in patient derived xenograft tumor models
F. Cattaruzza, P. Yeung, W. Yen, A. Brunner +9 more
20152 citations
Semantic Scholar
Abstract A30: Predictive and pharmacodynamic biomarkers of vantictumab (OMP-18R5; anti-Frizzled) in non-small cell lung cancer
Chun Zhang, F. Cattaruzza, P. Yeung, W. Yen +8 more
20152 citations
Semantic Scholar
Abstract 2576: Enhanced antitumor efficacy by sequential application of Wnt pathway antagonists in combination with taxanes
W. Yen, M. Fischer, B. Cancilla, F. Cattaruzza +5 more
20152 citations
Semantic Scholar
Cysteine Proteases in Supernatants From Colonic Biopsies Obtained From Diarrhea-Predominant IBS Patients Evoke Sustained Hyperexcitability of Colonic Dorsal Root Ganglia Neurons
Jeff Overington, Charles Ibeakanma, F. Ochoa-Cortes, N. Bunnett +2 more
20112 citations Open access
Semantic Scholar
Abstract 1824: HER2-XPAT, a novel protease-activatable T-cell engager (TCE) with potent T-cell activation and efficacy in solid tumors and large safety margins in non-human primate (NHP)
F. Cattaruzza, A. Nazeer, Z. Lange, C. Koski +7 more
2021Immunology1 citations
Semantic Scholar
Abstract PS17-11: Her2-xpat, a novel protease-activatable prodrug t-cell engager (tce), exhibits potent t-cell activation and efficacy in her2 tumors, yielding large predicted safety margins based on non-human primate (nhp)
F. Cattaruzza, A. Nazeer, Z. Lange, C. Koski +6 more
20211 citations
Semantic Scholar
1060P HER2-XPAT, a novel protease-activatable pro-drug T-cell engager (TCE), engineered to address on-target, off tumour toxicity and provide large predicted safety margins in non-human primate (NHP)
F. Cattaruzza, A. Nazeer, Z. Lange, C. Koski +6 more
2020Annals of Oncology1 citations Open access
Semantic Scholar
Abstract P3-07-57: Development of a 6-gene qPCR RUO-validated assay as a predictive biomarker for response of vantictumab (OMP-18R5; anti-frizzled) in HER2- breast cancer patients
Chun Zhang, G. O'young, K. Wikstrom, T. Davison +12 more
20161 citations
Semantic Scholar
Mediators of Chronic Stress and Tissue Proteases Interact to Potentiate the Excitability of Colonic Nociceptive Dorsal Root Ganglia Neurons in a Model of Post-Infectious IBS
Charles Ibeakanma, F. Ochoa-Cortes, I. Spreadbury, Todd G. McDonald +5 more
20111 citations Open access
Semantic Scholar
613 HER2-XPAT, a novel protease-activatable prodrug T cell engager (TCE), with potent T-cell activation and efficacy in solid tumors and large predicted safety margins in non-human primate (NHP)
F. Cattaruzza, A. Nazeer, Z. Lange, C. Koski +6 more
20200 citations Open access
Semantic Scholar
1062P EGFR-XPAT, a novel pro-drug T-cell engager (TCEs) engineered to address on-target, off-tumour toxicity and an orthogonal approach for cancer immunotherapy in EGFR, KRAS/BRAF cancers
B. Irving, A. Nazeer, F. Cattaruzza, Z. Lange +6 more
20200 citations Open access
Semantic Scholar
Abstract 3826: GITRL-Fc biomarker and mechanism study: GITRL-Fc reduces Treg frequency in tumors and requires effector function for inhibition of tumor growth
G. Argast, B. Cancilla, F. Cattaruzza, P. Yeung +14 more
2018Immunology0 citations
Semantic Scholar
Abstract 5621: Prevalence of GITR expression and pharmacodynamic (PD) biomarkers in syngeneic tumor models treated by a GITR agonist (GITRL-Fc)
Min Wang, F. Cattaruzza, P. Yeung, A. Brunner +12 more
20170 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

N. Bunnett×18
Invite
N. Bunnett — researcher profile on SciRah
A. Kapoun×16
Invite
A. Kapoun — researcher profile on SciRah
P. Yeung×15
Invite
P. Yeung — researcher profile on SciRah
J. Lewicki×13
Invite
J. Lewicki — researcher profile on SciRah

×12

Invite

T. Hoey — researcher profile on SciRah

B. Cancilla×11

Invite

B. Cancilla — researcher profile on SciRah

Invite

A. Gurney — researcher profile on SciRah

Invite

Min Wang — researcher profile on SciRah

Invite

W. Yen — researcher profile on SciRah

Invite

G. O'young — researcher profile on SciRah

Invite

M. Fischer — researcher profile on SciRah

Invite

A. Brunner — researcher profile on SciRah