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J. Cavarelli · SciRah

Researcher profile · Semantic Scholar

J. Cavarelli

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J. Cavarelli — researcher profile on SciRah

h-index: 32
Works: 134
Citations: 3,737

Most-cited papers

Translationally controlled tumor protein is a target of tumor reversion.
M. Tuynder, G. Fiucci, S. Prieur, A. Lespagnol +9 more
2004Proceedings of the National Academy of Sciences of the United States of America244 citations Open access
Semantic Scholar
TCTP protects from apoptotic cell death by antagonizing bax function
Laurent Susini, S. Besse, D. Duflaut, A. Lespagnol +11 more
2008Cell Death and Differentiation215 citations
Semantic Scholar
Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins
K. Zanier, S. Charbonnier, Abdellahi ould M’hamed ould Sidi, A. McEwen +11 more
2013Science198 citations Open access
Semantic Scholar
Functional insights from structures of coactivator‐associated arginine methyltransferase 1 domains
N. Troffer‐Charlier, V. Cura, P. Hassenboehler, D. Moras +1 more
2007EMBO Journal160 citations Open access
Semantic Scholar
Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni
M. Marek, S. Kannan, Alexander-Thomas Hauser, Marina Moraes Mourão +13 more
2013PLoS Pathogens155 citations Open access
Semantic Scholar
FFAT motif phosphorylation controls formation and lipid transfer function of inter‐organelle contacts
T. Di Mattia, Arthur Martinet, S. Ikhlef, A. McEwen +12 more
2020EMBO Journal122 citations Open access
Semantic Scholar
Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.
Elisabeth-Maria Bissinger, R. Heinke, Astrid Spannhoff, A. Eberlin +8 more
2011Bioorganic & Medicinal Chemistry109 citations Open access
Semantic Scholar
On the Structure and Function of the Phytoene Desaturase CRTI from Pantoea ananatis, a Membrane-Peripheral and FAD-Dependent Oxidase/Isomerase
Patrick Schaub, Qiu-Ju Yu, Sandra Gemmecker, P. Poussin-Courmontagne +6 more
2012PLoS ONE87 citations Open access
Semantic Scholar
The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26
Marie-Laure Diebold, M. Koch, Erin Loeliger, V. Cura +3 more
2010EMBO Journal73 citations Open access
Semantic Scholar
Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni.
D. Stolfa, M. Marek, Julien Lancelot, Alexander-Thomas Hauser +10 more
2014Journal of Molecular Biology69 citations Open access
Semantic Scholar
Crystal structure of the V-region of Streptococcus mutans antigen I/II at 2.4 A resolution suggests a sugar preformed binding site.
N. Troffer‐Charlier, J. Ogier, D. Moras, J. Cavarelli
2002Journal of Molecular Biology69 citations
Semantic Scholar
Noncanonical Tandem SH2 Enables Interaction of Elongation Factor Spt6 with RNA Polymerase II*
Marie-Laure Diebold, Erin Loeliger, M. Koch, F. Winston +2 more
2010Journal of Biological Chemistry65 citations Open access
Semantic Scholar
Structural basis for group A trichothiodystrophy
Denis E. Kainov, M. Vitorino, J. Cavarelli, A. Poterszman +1 more
2008Nature Structural &Molecular Biology62 citations
Semantic Scholar
TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL
S. Thébault, Morgane Agez, Xiao-Ke Chi, J. Stojko +19 more
2016Scientific Reports49 citations Open access
Semantic Scholar
Structural insight into arginine methylation by the mouse protein arginine methyltransferase 7: a zinc finger freezes the mimic of the dimeric state into a single active site.
V. Cura, N. Troffer‐Charlier, Jean-Marie Würtz, L. Bonnefond +1 more
2014Acta Crystallographica Section D: Biological Crystallography43 citations
Semantic Scholar
Structure, Activity and Function of the PRMT2 Protein Arginine Methyltransferase
V. Cura, J. Cavarelli
2021Life41 citations Open access
Semantic Scholar
Transition state mimics are valuable mechanistic probes for structural studies with the arginine methyltransferase CARM1
M. V. van Haren, N. Marechal, N. Troffer‐Charlier, Agostino Cianciulli +3 more
2017Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors
V. Cura, N. Marechal, N. Troffer‐Charlier, J. Strub +5 more
2017The FEBS Journal32 citations Open access
Semantic Scholar
Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors
L. Halby, N. Marechal, Dany Pechalrieu, V. Cura +15 more
2018Philosophical Transactions of the Royal Society B: Biological Sciences29 citations Open access
Semantic Scholar
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach
Giulia Iannelli, Ciro Milite, N. Marechal, V. Cura +11 more
2022Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1
S. Castellano, Astrid Spannhoff, Ciro Milite, F. Dal Piaz +12 more
2012Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Functional insights from high resolution structures of mouse protein arginine methyltransferase 6.
L. Bonnefond, J. Stojko, J. Mailliot, N. Troffer‐Charlier +4 more
2015Journal of Structural Biology25 citations
Semantic Scholar
Structure of the Elongator cofactor complex Kti11/Kti13 provides insight into the role of Kti13 in Elongator‐dependent tRNA modification
O. Kolaj-Robin, A. McEwen, J. Cavarelli, B. Séraphin
2015The FEBS Journal25 citations Open access
Semantic Scholar
Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus.
Tian-Wei Lin, J. Cavarelli, John E. Johnson
2003Virology24 citations Open access
Semantic Scholar
Biochemical and NMR Mapping of the Interface between CREB-binding Protein and Ligand Binding Domains of Nuclear Receptor
Fabrice A. C. Klein, R. Atkinson, N. Potier, D. Moras +1 more
2005Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Crystal structure, biochemical and genetic characterization of yeast and E. cuniculi TAF(II)5 N-terminal domain: implications for TFIID assembly.
C. Romier, Nicole James, C. Birck, J. Cavarelli +3 more
2007Journal of Molecular Biology21 citations Open access
Semantic Scholar
Crucial Role of the HIGH-loop Lysine for the Catalytic Activity of Arginyl-tRNA Synthetase*
S. Sekine, A. Shimada, O. Nureki, J. Cavarelli +3 more
2001Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Mutation and evolution of the magnesium-binding site of a class II aminoacyl-tRNA synthetase.
L. Ador, Sophie Jaeger, Renaud Geslain, Franck Martin +2 more
2004Biochemistry17 citations
Semantic Scholar
SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation
Anne-Sophie Gribling-Burrer, Michael Leichter, Laurence Wurth, A. Huttin +7 more
2017Nucleic Acids Research15 citations Open access
Semantic Scholar
Structural insights into transcription complexes.
I. Berger, A. G. Blanco, R. Boelens, J. Cavarelli +8 more
2011Journal of Structural Biology15 citations Open access
Semantic Scholar
Limited set of amino acid residues in a class Ia aminoacyl-tRNA synthetase is crucial for tRNA binding.
Renaud Geslain, G. Bey, J. Cavarelli, G. Eriani
2003Biochemistry13 citations
Semantic Scholar
Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation.
E. Salomon, Marjorie Schmitt, E. Mouray, A. McEwen +8 more
2020Bioorganic chemistry (Print)12 citations Open access
Semantic Scholar
Expression, purification, crystallization and preliminary crystallographic study of isolated modules of the mouse coactivator-associated arginine methyltransferase 1.
N. Troffer‐Charlier, V. Cura, P. Hassenboehler, D. Moras +1 more
2007Acta Crystallographica. Section F : Structural Biology and Crystallization Communications10 citations Open access
Semantic Scholar
The structure of an Iws 1 / Spt 6 complex reveals an interaction domain conserved in TFIIS , Elongin A and Med 26 Marie -
Lauren P. Diebold, M. Koch, Erin Loeliger, V. Cura +3 more
20109 citations
Semantic Scholar
Cloning, expression, purification and preliminary X-ray crystallographic analysis of mouse protein arginine methyltransferase 7.
V. Cura, N. Troffer‐Charlier, Marie Lambert, L. Bonnefond +1 more
2014Acta Crystallographica Section F Structural Biology Communications8 citations Open access
Semantic Scholar
Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis
G. Peng, A. McEwen, V. Olieric, C. Schmitt +3 more
2017Proteins: Structure, Function, and Bioinformatics7 citations
Semantic Scholar
Crystal structure of the V-region of Streptococcus mutans antigen I/II
N. Troffer‐Charlier, J. Ogier, D. Moras, J. Cavarelli
20027 citations
Semantic Scholar
Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors
Yurui Zhang, N. Marechal, M. V. van Haren, N. Troffer‐Charlier +3 more
2021ChemBioChem6 citations Open access
Semantic Scholar
Structure determination of the minimal complex between Tfb5 and Tfb2, two subunits of the yeast transcription/DNA-repair factor TFIIH: a retrospective study.
Denis E. Kainov, V. Cura, M. Vitorino, Hélène Nierengarten +4 more
2010Acta Crystallographica Section D: Biological Crystallography5 citations
Semantic Scholar
Crystallization and preliminary crystallographic analysis of eukaryotic transcription and mRNA export factor Iws1 from Encephalitozoon cuniculi.
M. Koch, Marie-Laure Diebold, J. Cavarelli, C. Romier
2010Acta Crystallographica. Section F : Structural Biology and Crystallization Communications5 citations Open access
Semantic Scholar
Structural Biology of Epigenetic Targets
C. Romier, Jean-Marie Würtz, J. Renaud, J. Cavarelli
20094 citations
Semantic Scholar
A Direct Assay for Measuring the Activity and Inhibition of Coactivator-Associated Arginine Methyltransferase 1
Yurui Zhang, M. V. van Haren, N. Marechal, N. Troffer‐Charlier +3 more
2022Biochemistry3 citations Open access
Semantic Scholar
Pushing induced fit to its limits: tRNA-dependent active site assembly in class I aminoacyl-tRNA synthetases.
J. Cavarelli
2003Structure3 citations Open access
Semantic Scholar
The 2.2 A crystal structure of the catalytic domain of coactivator-associated arginine methyl transferase I(CARM1,142-478), in complex with S-adenosyl homocysteine
N. Troffer‐Charlier, V. Cura, P. Hassenboehler, D. Moras +1 more
20072 citations
Semantic Scholar
CRYSTAL STRUCTURE OF HUMAN MYELOPEROXIDASE AT 1.7 ANGSTROMS RESOLUTION
L. Bonnefond, J. Cavarelli
20151 citations
Semantic Scholar
Crystal structure of full-length Bovine Papillomavirus oncoprotein E6 in complex with LD1 motif of paxillin at 2.3A resolution
J. Cavarelli
20111 citations
Semantic Scholar
Expression, purification, and characterization of a new heterotetramer structure of leucyl-tRNA synthetase from Aquifex aeolicus in Escherichia coli.
N. Olieric, G. Bey, Hélène Nierengarten, En-Duo Wang +3 more
2006Protein Expression and Purification1 citations
Semantic Scholar
A suite of macrocyclic peptide inhibitors and substrate probes for arginine methyltransferases
Ryoji Yoshisada, Yurui Zhang, Elwin Janssen, C. Bouchard +15 more
2026Chemical Science0 citations Open access
Semantic Scholar
Crystal structure of mouse CARM1 in complex with histone H3_13-31 K18
N. Marechal, V. Cura, N. Troffer‐Charlier, L. Bonnefond +1 more
20210 citations
Semantic Scholar
Crystal structure of mouse CARM1 in complex with histone H3_13-22 K18 acetylated
N. Marechal, V. Cura, N. Troffer‐Charlier, L. Bonnefond +1 more
20210 citations
Semantic Scholar

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